Planaria EST Database


DrC_01436

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01436
         (905 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q96PQ7|KLHL5_HUMAN  Kelch-like protein 5                        83   1e-15
sp|O60662|KBTBA_HUMAN  Kelch repeat and BTB domain containin...    79   1e-14
sp|Q9NR64|KLHL1_HUMAN  Kelch-like protein 1                        77   7e-14
sp|Q9JI74|KLHL1_MOUSE  Kelch-like protein 1                        77   9e-14
sp|Q9ER30|KBTBA_RAT  Kelch repeat and BTB domain containing ...    75   2e-13
sp|Q9C0H6|KLHL4_HUMAN  Kelch-like protein 4                        75   3e-13
sp|Q9D5V2|KLH10_MOUSE  Kelch-like protein 10                       74   7e-13
sp|Q6JEL3|KLH10_RAT  Kelch-like protein 10                         74   7e-13
sp|Q6JEL2|KLH10_HUMAN  Kelch-like protein 10                       73   1e-12
sp|Q9Y573|IPP_HUMAN  Actin-binding protein IPP (MIPP protein)      72   3e-12
>sp|Q96PQ7|KLHL5_HUMAN Kelch-like protein 5
          Length = 755

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 62/234 (26%), Positives = 96/234 (41%), Gaps = 4/234 (1%)
 Frame = +2

Query: 74   VTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVVTKDNVVYCAG 253
            V  +D KL  +GG  D    LN V+ Y+    +W  +PP+S    G  V   +  +Y  G
Sbjct: 509  VAVLDDKLYVVGG-RDGLKTLNTVECYNPKTKTWSVMPPMSTHRHGLGVAVLEGPMYAVG 567

Query: 254  GLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGGRDGKMFTSFSN 433
            G   G + L+  E  D    +W  +  M++        +     Y +GGRDG        
Sbjct: 568  G-HDGWSYLNTVERWDPQARQWNFVATMSTPRSTVGVAVLSGKLYAVGGRDGSSCLKSVE 626

Query: 434  CFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIP----TQGFSNLVFRFDL 601
            CFD   N W    ++    R            +Y IGG ++ P    T   S+ V R+D 
Sbjct: 627  CFDPHTNKWTLCAQM--SKRRGGVGVTTWNGLLYAIGG-HDAPASNLTSRLSDCVERYDP 683

Query: 602  QTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNKKWS 763
            +T+ W  + ++   R   G   + DKL   GG    Q    TVE ++    +W+
Sbjct: 684  KTDMWTAVASMSISRDAVGVCLLGDKLYAVGGYDG-QAYLNTVEAYDPQTNEWT 736

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 45/180 (25%), Positives = 70/180 (38%)
 Frame = +2

Query: 239 VYCAGGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGGRDGKMF 418
           ++  GG+ +     S  E  DL    W  +  MN         +  D  YV+GGRDG   
Sbjct: 469 LFAVGGMDSTKGATS-IEKYDLRTNMWTPVANMNGRRLQFGVAVLDDKLYVVGGRDGLKT 527

Query: 419 TSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQGFSNLVFRFD 598
            +   C++ +   W  +P  P                +Y +GG +      + N V R+D
Sbjct: 528 LNTVECYNPKTKTWSVMP--PMSTHRHGLGVAVLEGPMYAVGGHD---GWSYLNTVERWD 582

Query: 599 LQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNKKWSLLDDM 778
            Q  +W  +  +  PR+  G   +  KL   GG      L  +VE F+    KW+L   M
Sbjct: 583 PQARQWNFVATMSTPRSTVGVAVLSGKLYAVGGRDGSSCL-KSVECFDPHTNKWTLCAQM 641

 Score = 39.3 bits (90), Expect = 0.015
 Identities = 20/48 (41%), Positives = 27/48 (56%)
 Frame = +2

Query: 83  IDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVVT 226
           +  KL  +GG YD Q +LN V+AYD   + W ++ PL     G  VVT
Sbjct: 706 LGDKLYAVGG-YDGQAYLNTVEAYDPQTNEWTQVAPLCLGRAGACVVT 752

 Score = 38.5 bits (88), Expect = 0.026
 Identities = 31/154 (20%), Positives = 60/154 (38%)
 Frame = +2

Query: 380 TFYVIGGRDGKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEI 559
           T + +GG D     +    +D R N W   P      R            +Y++GG + +
Sbjct: 468 TLFAVGGMDSTKGATSIEKYDLRTNMW--TPVANMNGRRLQFGVAVLDDKLYVVGGRDGL 525

Query: 560 PTQGFSNLVFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELF 739
            T    N V  ++ +T+ W  +P +   R   G   ++  +   GG      L  TVE +
Sbjct: 526 KT---LNTVECYNPKTKTWSVMPPMSTHRHGLGVAVLEGPMYAVGGHDGWSYL-NTVERW 581

Query: 740 NIPNKKWSLLDDMPNVHASSTKCMADKSMFLVSG 841
           +   ++W+ +  M    ++    +    ++ V G
Sbjct: 582 DPQARQWNFVATMSTPRSTVGVAVLSGKLYAVGG 615
>sp|O60662|KBTBA_HUMAN Kelch repeat and BTB domain containing protein 10 (Kelch-related
           protein 1) (Kel-like protein 23) (Sarcosin)
          Length = 606

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 58/223 (26%), Positives = 99/223 (44%), Gaps = 7/223 (3%)
 Frame = +2

Query: 200 PAQGNIVVTKDNVVYCAGGL-----STGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNG 364
           P   + +VT+ N +Y  GGL     +      S F  LD     W  LP + S+      
Sbjct: 334 PRNHSSIVTQQNQIYVVGGLYVDEENKDQPLQSYFFQLDSIASEWVGLPPLPSARCLFGL 393

Query: 365 FIYRDTFYVIGGRDGKMFTSFSN--CFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYL 538
               D  YV+ G+D +   S  +  C+D  A  W  + K+P   +            +Y 
Sbjct: 394 GEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWNEVKKLP--IKVYGHNVISHKGMIYC 451

Query: 539 IGGLNEIPTQGFSNLVFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGL 718
           +GG  +   +  +N VF F+ +   W+ L  +  PR+ FG      K++IAGG+    GL
Sbjct: 452 LGGKTD--DKKCTNRVFIFNPKKGDWKDLAPMKIPRSMFGVAVHKGKIVIAGGVTE-DGL 508

Query: 719 AATVELFNIPNKKWSLLDDMPNVHASSTKCMADKSMFLVSGMS 847
           +A+VE F++   KW ++ + P   +S +      S++ + G +
Sbjct: 509 SASVEAFDLTTNKWDVMTEFPQERSSISLVSLAGSLYAIGGFA 551

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 52/242 (21%), Positives = 95/242 (39%), Gaps = 7/242 (2%)
 Frame = +2

Query: 8    DLSDRQCFRDFKDLPRAKAGSSVTHIDQKLITIGGIY-DKQCHLNNVDAYDVGMDS---- 172
            D ++ +C+         +  SS+     ++  +GG+Y D++     + +Y   +DS    
Sbjct: 318  DPTENECYLTALAEQIPRNHSSIVTQQNQIYVVGGLYVDEENKDQPLQSYFFQLDSIASE 377

Query: 173  WEELPPL-SNPAQGNIVVTKDNVVYCAGGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSH 349
            W  LPPL S      +    D +   AG       +L +    D    +W  + K+    
Sbjct: 378  WVGLPPLPSARCLFGLGEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWNEVKKLPIKV 437

Query: 350  FNTNGFIYRDTFYVIGGR-DGKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXX 526
            +  N   ++   Y +GG+ D K  T+    F+ +   W++L   P +             
Sbjct: 438  YGHNVISHKGMIYCLGGKTDDKKCTNRVFIFNPKKGDWKDLA--PMKIPRSMFGVAVHKG 495

Query: 527  HVYLIGGLNEIPTQGFSNLVFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGN 706
             + + GG+ E    G S  V  FDL T KW+ +    + R+     ++   L   GG   
Sbjct: 496  KIVIAGGVTE---DGLSASVEAFDLTTNKWDVMTEFPQERSSISLVSLAGSLYAIGGFAM 552

Query: 707  LQ 712
            +Q
Sbjct: 553  IQ 554
>sp|Q9NR64|KLHL1_HUMAN Kelch-like protein 1
          Length = 748

 Score = 77.0 bits (188), Expect = 7e-14
 Identities = 62/233 (26%), Positives = 92/233 (39%), Gaps = 3/233 (1%)
 Frame = +2

Query: 74   VTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVVTKDNVVYCAG 253
            V  ID KL  IGG  D    LN V+ Y+    +W  LPP+S    G  V   +  +Y  G
Sbjct: 501  VAVIDDKLFVIGG-RDGLKTLNTVECYNPKTKTWTVLPPMSTHRHGLGVTVLEGPIYAVG 559

Query: 254  GLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGGRDGKMFTSFSN 433
            G   G + L+  E  D    +W  +  M+ +             Y +GGRDG    S   
Sbjct: 560  G-HDGWSYLNTVERWDPQSQQWTFVASMSIARSTVGVAALNGKLYSVGGRDGSSCLSSME 618

Query: 434  CFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQGFSNL---VFRFDLQ 604
             +D   N W      P   R            +Y +GG +   +   S L   V R+D +
Sbjct: 619  YYDPHTNKWNMC--APMCKRRGGVGVATCDGFLYAVGGHDAPASNHCSRLLDYVERYDPK 676

Query: 605  TEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNKKWS 763
            T+ W  +  +  PR   G   + D+L   GG    Q    T+E ++    +W+
Sbjct: 677  TDTWTMVAPLSMPRDAVGVCLLGDRLYAVGGYDG-QTYLNTMESYDPQTNEWT 728

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 48/203 (23%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
 Frame = +2

Query: 239  VYCAGGLST--GMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGGRDGK 412
            +Y  GG+    G TT+  +   DL    W     MN         +  D  +VIGGRDG 
Sbjct: 461  LYAVGGMDNNKGATTIEKY---DLRTNLWIQAGMMNGRRLQFGVAVIDDKLFVIGGRDGL 517

Query: 413  MFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQGFSNLVFR 592
               +   C++ +   W  LP  P                +Y +GG +      + N V R
Sbjct: 518  KTLNTVECYNPKTKTWTVLP--PMSTHRHGLGVTVLEGPIYAVGGHD---GWSYLNTVER 572

Query: 593  FDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNKKWSLLD 772
            +D Q+++W  + ++   R+  G  A++ KL   GG      L +++E ++    KW++  
Sbjct: 573  WDPQSQQWTFVASMSIARSTVGVAALNGKLYSVGGRDGSSCL-SSMEYYDPHTNKWNMCA 631

Query: 773  DMPNVHASSTKCMADKSMFLVSG 841
             M            D  ++ V G
Sbjct: 632  PMCKRRGGVGVATCDGFLYAVGG 654

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 32/146 (21%), Positives = 59/146 (40%), Gaps = 5/146 (3%)
 Frame = +2

Query: 56   AKAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVVTKDN 235
            A++   V  ++ KL ++GG     C L++++ YD   + W    P+     G  V T D 
Sbjct: 589  ARSTVGVAALNGKLYSVGGRDGSSC-LSSMEYYDPHTNKWNMCAPMCKRRGGVGVATCDG 647

Query: 236  VVYCAGGLSTGMTT-----LSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGG 400
             +Y  GG     +      L   E  D     W ++  ++         +  D  Y +GG
Sbjct: 648  FLYAVGGHDAPASNHCSRLLDYVERYDPKTDTWTMVAPLSMPRDAVGVCLLGDRLYAVGG 707

Query: 401  RDGKMFTSFSNCFDFRANAWRNLPKI 478
             DG+ + +    +D + N W  +  +
Sbjct: 708  YDGQTYLNTMESYDPQTNEWTQMASL 733

 Score = 38.1 bits (87), Expect = 0.034
 Identities = 32/154 (20%), Positives = 61/154 (39%)
 Frame = +2

Query: 380 TFYVIGGRDGKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEI 559
           T Y +GG D     +    +D R N W     +    R            +++IGG + +
Sbjct: 460 TLYAVGGMDNNKGATTIEKYDLRTNLWIQAGMM--NGRRLQFGVAVIDDKLFVIGGRDGL 517

Query: 560 PTQGFSNLVFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELF 739
            T    N V  ++ +T+ W  LP +   R   G   ++  +   GG      L  TVE +
Sbjct: 518 KT---LNTVECYNPKTKTWTVLPPMSTHRHGLGVTVLEGPIYAVGGHDGWSYL-NTVERW 573

Query: 740 NIPNKKWSLLDDMPNVHASSTKCMADKSMFLVSG 841
           +  +++W+ +  M    ++      +  ++ V G
Sbjct: 574 DPQSQQWTFVASMSIARSTVGVAALNGKLYSVGG 607

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 19/59 (32%), Positives = 31/59 (52%)
 Frame = +2

Query: 47  LPRAKAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVV 223
           +PR   G  V  +  +L  +GG YD Q +LN +++YD   + W ++  L+    G  VV
Sbjct: 688 MPRDAVG--VCLLGDRLYAVGG-YDGQTYLNTMESYDPQTNEWTQMASLNIGRAGACVV 743
>sp|Q9JI74|KLHL1_MOUSE Kelch-like protein 1
          Length = 751

 Score = 76.6 bits (187), Expect = 9e-14
 Identities = 61/233 (26%), Positives = 93/233 (39%), Gaps = 3/233 (1%)
 Frame = +2

Query: 74   VTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVVTKDNVVYCAG 253
            V  ID KL  IGG  D    LN V+ Y+    +W  LPP+S    G  V   +  +Y  G
Sbjct: 504  VAVIDDKLFVIGG-RDGLKTLNTVECYNPKTKTWTVLPPMSTHRHGLGVTVLEGPIYAVG 562

Query: 254  GLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGGRDGKMFTSFSN 433
            G   G + L+  E  D    +W  +  M+ +             Y +GGRDG    S   
Sbjct: 563  G-HDGWSYLNTVERWDPQSQQWTYVASMSIARSTVGVAALNGKLYSVGGRDGSSCLSSME 621

Query: 434  CFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQGFSNL---VFRFDLQ 604
             +D   N W   P  P   +            +Y +GG +   +   S L   V R++ +
Sbjct: 622  YYDPHTNKWSMCP--PMCKKRGGVGVATCDGFLYAVGGHDAPASNHCSRLLDYVERYEPK 679

Query: 605  TEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNKKWS 763
            T+ W  +  +  PR   G   + D+L   GG    Q    T+E ++    +W+
Sbjct: 680  TDTWTMVAPLSMPRDAVGVCLLGDRLYAVGGYDG-QTYLNTMESYDPQTNEWT 731

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 49/203 (24%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
 Frame = +2

Query: 239  VYCAGGLST--GMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGGRDGK 412
            +Y  GG+    G TT+  +   DL    W     MN         +  D  +VIGGRDG 
Sbjct: 464  LYAVGGMDNNKGATTIEKY---DLRTNLWIQAGMMNGRRLQFGVAVIDDKLFVIGGRDGL 520

Query: 413  MFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQGFSNLVFR 592
               +   C++ +   W  LP  P                +Y +GG +      + N V R
Sbjct: 521  KTLNTVECYNPKTKTWTVLP--PMSTHRHGLGVTVLEGPIYAVGGHD---GWSYLNTVER 575

Query: 593  FDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNKKWSLLD 772
            +D Q+++W  + ++   R+  G  A++ KL   GG      L +++E ++    KWS+  
Sbjct: 576  WDPQSQQWTYVASMSIARSTVGVAALNGKLYSVGGRDGSSCL-SSMEYYDPHTNKWSMCP 634

Query: 773  DMPNVHASSTKCMADKSMFLVSG 841
             M            D  ++ V G
Sbjct: 635  PMCKKRGGVGVATCDGFLYAVGG 657

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 32/146 (21%), Positives = 60/146 (41%), Gaps = 5/146 (3%)
 Frame = +2

Query: 56   AKAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVVTKDN 235
            A++   V  ++ KL ++GG     C L++++ YD   + W   PP+     G  V T D 
Sbjct: 592  ARSTVGVAALNGKLYSVGGRDGSSC-LSSMEYYDPHTNKWSMCPPMCKKRGGVGVATCDG 650

Query: 236  VVYCAGGLSTGMTT-----LSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGG 400
             +Y  GG     +      L   E  +     W ++  ++         +  D  Y +GG
Sbjct: 651  FLYAVGGHDAPASNHCSRLLDYVERYEPKTDTWTMVAPLSMPRDAVGVCLLGDRLYAVGG 710

Query: 401  RDGKMFTSFSNCFDFRANAWRNLPKI 478
             DG+ + +    +D + N W  +  +
Sbjct: 711  YDGQTYLNTMESYDPQTNEWTQMASL 736

 Score = 37.7 bits (86), Expect = 0.045
 Identities = 32/154 (20%), Positives = 61/154 (39%)
 Frame = +2

Query: 380 TFYVIGGRDGKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEI 559
           T Y +GG D     +    +D R N W     +    R            +++IGG + +
Sbjct: 463 TLYAVGGMDNNKGATTIEKYDLRTNLWIQAGMM--NGRRLQFGVAVIDDKLFVIGGRDGL 520

Query: 560 PTQGFSNLVFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELF 739
            T    N V  ++ +T+ W  LP +   R   G   ++  +   GG      L  TVE +
Sbjct: 521 KT---LNTVECYNPKTKTWTVLPPMSTHRHGLGVTVLEGPIYAVGGHDGWSYL-NTVERW 576

Query: 740 NIPNKKWSLLDDMPNVHASSTKCMADKSMFLVSG 841
           +  +++W+ +  M    ++      +  ++ V G
Sbjct: 577 DPQSQQWTYVASMSIARSTVGVAALNGKLYSVGG 610

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 19/59 (32%), Positives = 31/59 (52%)
 Frame = +2

Query: 47  LPRAKAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVV 223
           +PR   G  V  +  +L  +GG YD Q +LN +++YD   + W ++  L+    G  VV
Sbjct: 691 MPRDAVG--VCLLGDRLYAVGG-YDGQTYLNTMESYDPQTNEWTQMASLNIGRAGACVV 746
>sp|Q9ER30|KBTBA_RAT Kelch repeat and BTB domain containing protein 10 (Kelch-related
           protein 1) (Kel-like protein 23) (Sarcosin)
          Length = 606

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 57/223 (25%), Positives = 98/223 (43%), Gaps = 7/223 (3%)
 Frame = +2

Query: 200 PAQGNIVVTKDNVVYCAGGL-----STGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNG 364
           P   + +VT+ N VY  GGL     +      S F  LD     W  LP + S+      
Sbjct: 334 PRNHSSIVTQQNQVYVVGGLYVDEENKDQPLQSYFFQLDNVSSEWVGLPPLPSARCLFGL 393

Query: 365 FIYRDTFYVIGGRDGKMFTSFSN--CFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYL 538
               D  YV+ G+D +   S  +  C+D  A  W  +  +P   +            +Y 
Sbjct: 394 GEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWSEVKNLP--IKVYGHNVISHNGMIYC 451

Query: 539 IGGLNEIPTQGFSNLVFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGL 718
           +GG  +   +  +N VF ++ +   W+ L  +  PR+ FG      K++IAGG+    GL
Sbjct: 452 LGGKTD--DKKCTNRVFIYNPKKGDWKDLAPMKTPRSMFGVAIHKGKIVIAGGVTE-DGL 508

Query: 719 AATVELFNIPNKKWSLLDDMPNVHASSTKCMADKSMFLVSGMS 847
           +A+VE F++   KW ++ + P   +S +      S++ + G +
Sbjct: 509 SASVEAFDLKTNKWEVMTEFPQERSSISLVSLAGSLYAIGGFA 551

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 32/148 (21%), Positives = 61/148 (41%), Gaps = 1/148 (0%)
 Frame = +2

Query: 47  LPRAKAGSSVTHIDQKLITIGGI-YDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVV 223
           LP A+    +  +D K+  + G     +  L++V  YD     W E+  L     G+ V+
Sbjct: 384 LPSARCLFGLGEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWSEVKNLPIKVYGHNVI 443

Query: 224 TKDNVVYCAGGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGGR 403
           + + ++YC GG +      +   + +   G W+ L  M +        I++    + GG 
Sbjct: 444 SHNGMIYCLGGKTDDKKCTNRVFIYNPKKGDWKDLAPMKTPRSMFGVAIHKGKIVIAGGV 503

Query: 404 DGKMFTSFSNCFDFRANAWRNLPKIPDE 487
                ++    FD + N W  + + P E
Sbjct: 504 TEDGLSASVEAFDLKTNKWEVMTEFPQE 531

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 48/222 (21%), Positives = 87/222 (39%), Gaps = 7/222 (3%)
 Frame = +2

Query: 68  SSVTHIDQKLITIGGIY-DKQCHLNNVDAYDVGMDS----WEELPPL-SNPAQGNIVVTK 229
           SS+     ++  +GG+Y D++     + +Y   +D+    W  LPPL S      +    
Sbjct: 338 SSIVTQQNQVYVVGGLYVDEENKDQPLQSYFFQLDNVSSEWVGLPPLPSARCLFGLGEVD 397

Query: 230 DNVVYCAGGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGGR-D 406
           D +   AG       +L +    D    +W  +  +    +  N   +    Y +GG+ D
Sbjct: 398 DKIYVVAGKDLQTEASLDSVLCYDPVAAKWSEVKNLPIKVYGHNVISHNGMIYCLGGKTD 457

Query: 407 GKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQGFSNLV 586
            K  T+    ++ +   W++L   P +              + + GG+ E    G S  V
Sbjct: 458 DKKCTNRVFIYNPKKGDWKDLA--PMKTPRSMFGVAIHKGKIVIAGGVTE---DGLSASV 512

Query: 587 FRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQ 712
             FDL+T KWE +    + R+     ++   L   GG   +Q
Sbjct: 513 EAFDLKTNKWEVMTEFPQERSSISLVSLAGSLYAIGGFAMIQ 554

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 27/123 (21%), Positives = 54/123 (43%), Gaps = 1/123 (0%)
 Frame = +2

Query: 35  DFKDLPRAKAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNP-AQG 211
           + K+LP    G +V   +  +  +GG  D +   N V  Y+     W++L P+  P +  
Sbjct: 429 EVKNLPIKVYGHNVISHNGMIYCLGGKTDDKKCTNRVFIYNPKKGDWKDLAPMKTPRSMF 488

Query: 212 NIVVTKDNVVYCAGGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYV 391
            + + K  +V   G    G++  ++ E  DL   +W+++ +      + +      + Y 
Sbjct: 489 GVAIHKGKIVIAGGVTEDGLS--ASVEAFDLKTNKWEVMTEFPQERSSISLVSLAGSLYA 546

Query: 392 IGG 400
           IGG
Sbjct: 547 IGG 549
>sp|Q9C0H6|KLHL4_HUMAN Kelch-like protein 4
          Length = 718

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 61/233 (26%), Positives = 92/233 (39%), Gaps = 4/233 (1%)
 Frame = +2

Query: 74   VTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVVTKDNVVYCAG 253
            V  ID KL  +GG  D    LN V+ ++     W  +PP+S    G  V T +  +Y  G
Sbjct: 471  VAVIDNKLYVVGG-RDGLKTLNTVECFNPVGKIWTVMPPMSTHRHGLGVATLEGPMYAVG 529

Query: 254  GLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGGRDGKMFTSFSN 433
            G   G + L+  E  D    +W  +  M++           +  Y IGGRDG        
Sbjct: 530  G-HDGWSYLNTVERWDPEGRQWNYVASMSTPRSTVGVVALNNKLYAIGGRDGSSCLKSME 588

Query: 434  CFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQG----FSNLVFRFDL 601
             FD   N W      P   R            +Y++GG ++ P        S+ V R+D 
Sbjct: 589  YFDPHTNKWSLC--APMSKRRGGVGVATYNGFLYVVGG-HDAPASNHCSRLSDCVERYDP 645

Query: 602  QTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNKKW 760
            + + W  +  +  PR       + DKL + GG      L  TVE ++    +W
Sbjct: 646  KGDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYL-NTVESYDAQRNEW 697

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 46/180 (25%), Positives = 73/180 (40%)
 Frame = +2

Query: 239 VYCAGGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGGRDGKMF 418
           +Y  GG+   M   +  E  DL    W  +  MN         +  +  YV+GGRDG   
Sbjct: 431 LYAVGGMDA-MKGTTTIEKYDLRTNSWLHIGTMNGRRLQFGVAVIDNKLYVVGGRDGLKT 489

Query: 419 TSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQGFSNLVFRFD 598
            +   CF+     W  +P  P                +Y +GG +      + N V R+D
Sbjct: 490 LNTVECFNPVGKIWTVMP--PMSTHRHGLGVATLEGPMYAVGGHD---GWSYLNTVERWD 544

Query: 599 LQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNKKWSLLDDM 778
            +  +W  + ++  PR+  G  A+++KL   GG      L  ++E F+    KWSL   M
Sbjct: 545 PEGRQWNYVASMSTPRSTVGVVALNNKLYAIGGRDGSSCL-KSMEYFDPHTNKWSLCAPM 603

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 59/277 (21%), Positives = 97/277 (35%), Gaps = 7/277 (2%)
 Frame = +2

Query: 32   RDFKDLPRAKAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQG 211
            R     PR K   S       L  +GG+ D       ++ YD+  +SW  +  ++     
Sbjct: 413  RSMMQSPRTKPRKSTVGA---LYAVGGM-DAMKGTTTIEKYDLRTNSWLHIGTMNGRRLQ 468

Query: 212  NIVVTKDNVVYCAGGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYV 391
              V   DN +Y  GG   G+ TL+  E  +     W ++P M++              Y 
Sbjct: 469  FGVAVIDNKLYVVGG-RDGLKTLNTVECFNPVGKIWTVMPPMSTHRHGLGVATLEGPMYA 527

Query: 392  IGGRDGKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQG 571
            +GG DG  + +    +D     W  +  +                 +Y IGG       G
Sbjct: 528  VGGHDGWSYLNTVERWDPEGRQWNYVASMSTP--RSTVGVVALNNKLYAIGG-----RDG 580

Query: 572  FSNL--VFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGG-----MGNLQGLAATV 730
             S L  +  FD  T KW     + K R   G    +  L + GG       +   L+  V
Sbjct: 581  SSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATYNGFLYVVGGHDAPASNHCSRLSDCV 640

Query: 731  ELFNIPNKKWSLLDDMPNVHASSTKCMADKSMFLVSG 841
            E ++     WS +  +     +   C     +++V G
Sbjct: 641  ERYDPKGDSWSTVAPLSVPRDAVAVCPLGDKLYVVGG 677

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 37/143 (25%), Positives = 59/143 (41%), Gaps = 5/143 (3%)
 Frame = +2

Query: 50  PRAKAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVVTK 229
           PR+  G  V  ++ KL  IGG     C L +++ +D   + W    P+S    G  V T 
Sbjct: 559 PRSTVG--VVALNNKLYAIGGRDGSSC-LKSMEYFDPHTNKWSLCAPMSKRRGGVGVATY 615

Query: 230 DNVVYCAGG----LSTGMTTLSN-FEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVI 394
           +  +Y  GG     S   + LS+  E  D     W  +  ++            D  YV+
Sbjct: 616 NGFLYVVGGHDAPASNHCSRLSDCVERYDPKGDSWSTVAPLSVPRDAVAVCPLGDKLYVV 675

Query: 395 GGRDGKMFTSFSNCFDFRANAWR 463
           GG DG  + +    +D + N W+
Sbjct: 676 GGYDGHTYLNTVESYDAQRNEWK 698

 Score = 35.0 bits (79), Expect = 0.29
 Identities = 18/51 (35%), Positives = 28/51 (54%)
 Frame = +2

Query: 71  SVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVV 223
           +V  +  KL  +GG YD   +LN V++YD   + W+E  P++    G  VV
Sbjct: 664 AVCPLGDKLYVVGG-YDGHTYLNTVESYDAQRNEWKEEVPVNIGRAGACVV 713
>sp|Q9D5V2|KLH10_MOUSE Kelch-like protein 10
          Length = 608

 Score = 73.6 bits (179), Expect = 7e-13
 Identities = 56/258 (21%), Positives = 105/258 (40%), Gaps = 2/258 (0%)
 Frame = +2

Query: 41   KDLPRAKAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIV 220
            ++ PRA  G++  ++   +  IGG +D   + N+V  +D    +W ++ P+ +      V
Sbjct: 325  EESPRAYHGAA--YLKGYVYIIGG-FDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSV 381

Query: 221  VTKDNVVYCAGGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGG 400
                N +Y  GG   G   L+  E  +    +W ++  M+    + +        Y+ GG
Sbjct: 382  TVLSNFIYAMGGFD-GYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGG 440

Query: 401  RDGKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQGFSN 580
             +G      +  ++  +N W  +   P   R           HVY +GG +     G + 
Sbjct: 441  FNGNECLFTAEVYNTESNQWTVIA--PMRSRRSGIGVIAYGEHVYAVGGFD-----GANR 493

Query: 581  L--VFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNK 754
            L     +      W  +P +  PR++FG   +DD L + GG          VE ++    
Sbjct: 494  LRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFT-TTFNVECYDEKTD 552

Query: 755  KWSLLDDMPNVHASSTKC 808
            +W    DM +++ S+  C
Sbjct: 553  EWYDAHDM-SIYRSALSC 569

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 32/154 (20%), Positives = 61/154 (39%)
 Frame = +2

Query: 386 YVIGGRDGKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPT 565
           + IGG  G   T+    +D RA+ W N+    +E             +VY+IGG + +  
Sbjct: 294 FAIGGWSGGSPTNAIEAYDARADRWVNV-TCEEESPRAYHGAAYLKGYVYIIGGFDSV-- 350

Query: 566 QGFSNLVFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNI 745
             + N V RFD   + W ++  +   R       + + +   GG      L  T E +  
Sbjct: 351 -DYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLSNFIYAMGGFDGYVRL-NTAERYEP 408

Query: 746 PNKKWSLLDDMPNVHASSTKCMADKSMFLVSGMS 847
              +W+L+  M    + ++       +++  G +
Sbjct: 409 ETNQWTLIAPMHEQRSDASATTLYGKVYICGGFN 442
>sp|Q6JEL3|KLH10_RAT Kelch-like protein 10
          Length = 608

 Score = 73.6 bits (179), Expect = 7e-13
 Identities = 56/258 (21%), Positives = 105/258 (40%), Gaps = 2/258 (0%)
 Frame = +2

Query: 41   KDLPRAKAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIV 220
            ++ PRA  G++  ++   +  IGG +D   + N+V  +D    +W ++ P+ +      V
Sbjct: 325  EESPRAYHGAA--YLKGYVYIIGG-FDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSV 381

Query: 221  VTKDNVVYCAGGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGG 400
                N +Y  GG   G   L+  E  +    +W ++  M+    + +        Y+ GG
Sbjct: 382  TVLSNFIYAMGGFD-GYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGG 440

Query: 401  RDGKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQGFSN 580
             +G      +  ++  +N W  +   P   R           HVY +GG +     G + 
Sbjct: 441  FNGNECLFTAEVYNTESNQWTVIA--PMRSRRSGIGVIAYGEHVYAVGGFD-----GANR 493

Query: 581  L--VFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNK 754
            L     +      W  +P +  PR++FG   +DD L + GG          VE ++    
Sbjct: 494  LRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFT-TTFNVECYDEKTD 552

Query: 755  KWSLLDDMPNVHASSTKC 808
            +W    DM +++ S+  C
Sbjct: 553  EWYDAHDM-SIYRSALSC 569

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 32/154 (20%), Positives = 61/154 (39%)
 Frame = +2

Query: 386 YVIGGRDGKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPT 565
           + IGG  G   T+    +D RA+ W N+    +E             +VY+IGG + +  
Sbjct: 294 FAIGGWSGGSPTNAIEAYDARADRWVNV-TCEEESPRAYHGAAYLKGYVYIIGGFDSV-- 350

Query: 566 QGFSNLVFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNI 745
             + N V RFD   + W ++  +   R       + + +   GG      L  T E +  
Sbjct: 351 -DYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLSNFIYAMGGFDGYVRL-NTAERYEP 408

Query: 746 PNKKWSLLDDMPNVHASSTKCMADKSMFLVSGMS 847
              +W+L+  M    + ++       +++  G +
Sbjct: 409 ETNQWTLIAPMHEQRSDASATTLYGKVYICGGFN 442
>sp|Q6JEL2|KLH10_HUMAN Kelch-like protein 10
          Length = 608

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 56/258 (21%), Positives = 105/258 (40%), Gaps = 2/258 (0%)
 Frame = +2

Query: 41   KDLPRAKAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIV 220
            ++ PRA  G++  ++   +  IGG +D   + N+V  +D    +W ++ P+ +      V
Sbjct: 325  EESPRAYHGAA--YLKGYVYIIGG-FDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSV 381

Query: 221  VTKDNVVYCAGGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGG 400
                N +Y  GG   G   L+  E  +    +W ++  M+    + +        Y+ GG
Sbjct: 382  TVLGNFIYAMGGFD-GYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGG 440

Query: 401  RDGKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQGFSN 580
             +G      +  ++  +N W  +   P   R           HVY +GG +     G + 
Sbjct: 441  FNGNECLFTAEVYNTESNQWTVIA--PMRSRRSGIGVIAYGEHVYAVGGFD-----GANR 493

Query: 581  L--VFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNK 754
            L     +      W  +P +  PR++FG   +DD L + GG          VE ++    
Sbjct: 494  LRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFT-TTFNVECYDEKTD 552

Query: 755  KWSLLDDMPNVHASSTKC 808
            +W    DM +++ S+  C
Sbjct: 553  EWYDAHDM-SIYRSALSC 569

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 32/154 (20%), Positives = 61/154 (39%)
 Frame = +2

Query: 386 YVIGGRDGKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPT 565
           + IGG  G   T+    +D RA+ W N+    +E             +VY+IGG + +  
Sbjct: 294 FAIGGWSGGSPTNAIEAYDARADRWVNV-TCEEESPRAYHGAAYLKGYVYIIGGFDSV-- 350

Query: 566 QGFSNLVFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNI 745
             + N V RFD   + W ++  +   R       + + +   GG      L  T E +  
Sbjct: 351 -DYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLGNFIYAMGGFDGYVRL-NTAERYEP 408

Query: 746 PNKKWSLLDDMPNVHASSTKCMADKSMFLVSGMS 847
              +W+L+  M    + ++       +++  G +
Sbjct: 409 ETNQWTLIAPMHEQRSDASATTLYGKVYICGGFN 442
>sp|Q9Y573|IPP_HUMAN Actin-binding protein IPP (MIPP protein)
          Length = 584

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 63/259 (24%), Positives = 108/259 (41%), Gaps = 7/259 (2%)
 Frame = +2

Query: 23   QCFRDFKDLPRAKAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNP 202
            Q +     L +A++G  VT +   +  IGG  D     +  + YD     W  +  +++P
Sbjct: 321  QYWTTVSSLHQARSGLGVTVLGGMVYAIGGEKDSMI-FDCTECYDPVTKQWTTVASMNHP 379

Query: 203  AQGNIVVTKDNVVYCAGGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDT 382
              G  V      +Y  GG   G    +  E  D    +W+++  M  S +       +  
Sbjct: 380  RCGLGVCVCYGAIYALGGW-VGAEIGNTIERFDPDENKWEVVGNMAVSRYYFGCCEMQGL 438

Query: 383  FYVIGG--RDGKMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNE 556
             YVIGG   +G    SF   +D  +  W  LP  P   R            +Y +GG NE
Sbjct: 439  IYVIGGISNEGIELRSFE-VYDPLSKRWSPLP--PMGTRRAYLGVAALNDCIYSVGGWNE 495

Query: 557  IPTQGFSNLVFRFDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGN-----LQGLA 721
              TQ   + V ++  + EKW ++ ++  PRA     A++  L ++GG  +       G  
Sbjct: 496  --TQDALHTVEKYSFEEEKWVEVASMKVPRAGMCVVAVNGLLYVSGGRSSSHDFLAPGTL 553

Query: 722  ATVELFNIPNKKWSLLDDM 778
             +VE++N  +  W+ + +M
Sbjct: 554  DSVEVYNPHSDTWTEIGNM 572

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 60/265 (22%), Positives = 95/265 (35%), Gaps = 1/265 (0%)
 Frame = +2

Query: 50   PRAKAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVVTK 229
            PR KA   +  +       GG +     L+ V+ +D     W  +  L     G  V   
Sbjct: 282  PRKKARKYLYAVGGYTRLQGGRWSDSRALSCVERFDTFSQYWTTVSSLHQARSGLGVTVL 341

Query: 230  DNVVYCAGGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGGRDG 409
              +VY  GG    M      E  D    +W  +  MN         +     Y +GG  G
Sbjct: 342  GGMVYAIGGEKDSMI-FDCTECYDPVTKQWTTVASMNHPRCGLGVCVCYGAIYALGGWVG 400

Query: 410  KMFTSFSNCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQGFSNLVF 589
                +    FD   N W  +  +                 +Y+IGG++    +G     F
Sbjct: 401  AEIGNTIERFDPDENKWEVVGNMA--VSRYYFGCCEMQGLIYVIGGISN---EGIELRSF 455

Query: 590  R-FDLQTEKWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNKKWSL 766
              +D  +++W  LP +   RA  G  A++D +   GG    Q    TVE ++   +KW  
Sbjct: 456  EVYDPLSKRWSPLPPMGTRRAYLGVAALNDCIYSVGGWNETQDALHTVEKYSFEEEKWVE 515

Query: 767  LDDMPNVHASSTKCMADKSMFLVSG 841
            +  M  V  +    +A   +  VSG
Sbjct: 516  VASM-KVPRAGMCVVAVNGLLYVSG 539

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 43/209 (20%), Positives = 76/209 (36%)
 Frame = +2

Query: 251 GGLSTGMTTLSNFEMLDLSVGRWQILPKMNSSHFNTNGFIYRDTFYVIGGRDGKMFTSFS 430
           GG  +    LS  E  D     W  +  ++ +       +     Y IGG    M    +
Sbjct: 301 GGRWSDSRALSCVERFDTFSQYWTTVSSLHQARSGLGVTVLGGMVYAIGGEKDSMIFDCT 360

Query: 431 NCFDFRANAWRNLPKIPDEYRXXXXXXXXXXXHVYLIGGLNEIPTQGFSNLVFRFDLQTE 610
            C+D     W  +  +   +             +Y +GG          N + RFD    
Sbjct: 361 ECYDPVTKQWTTVASM--NHPRCGLGVCVCYGAIYALGGWVGAE---IGNTIERFDPDEN 415

Query: 611 KWEKLPNILKPRADFGAFAIDDKLIIAGGMGNLQGLAATVELFNIPNKKWSLLDDMPNVH 790
           KWE + N+   R  FG   +   + + GG+ N      + E+++  +K+WS L  M    
Sbjct: 416 KWEVVGNMAVSRYYFGCCEMQGLIYVIGGISNEGIELRSFEVYDPLSKRWSPLPPMGTRR 475

Query: 791 ASSTKCMADKSMFLVSGMSPTGPSVNVTE 877
           A       +  ++ V G + T  +++  E
Sbjct: 476 AYLGVAALNDCIYSVGGWNETQDALHTVE 504

 Score = 36.6 bits (83), Expect = 0.099
 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
 Frame = +2

Query: 59  KAGSSVTHIDQKLITIGGIYDKQCHLNNVDAYDVGMDSWEELPPLSNPAQGNIVVTKDNV 238
           +A   V  ++  + ++GG  + Q  L+ V+ Y    + W E+  +  P  G  VV  + +
Sbjct: 475 RAYLGVAALNDCIYSVGGWNETQDALHTVEKYSFEEEKWVEVASMKVPRAGMCVVAVNGL 534

Query: 239 VYCAGGLSTGMT-----TLSNFEMLDLSVGRWQILPKMNSS 346
           +Y +GG S+        TL + E+ +     W  +  M +S
Sbjct: 535 LYVSGGRSSSHDFLAPGTLDSVEVYNPHSDTWTEIGNMITS 575
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 111,418,045
Number of Sequences: 369166
Number of extensions: 2395127
Number of successful extensions: 6432
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5660
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6089
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9174518830
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)