Planaria EST Database


DrC_01296

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01296
         (605 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q86YT6|MIB1_HUMAN  Ubiquitin ligase protein MIB1 (Mind bo...    50   6e-06
sp|Q80SY4|MIB1_MOUSE  Ubiquitin ligase protein MIB1 (Mind bo...    49   1e-05
sp|Q6GNY1|MIB1_XENLA  Ubiquitin ligase protein MIB1 (Mind bo...    48   2e-05
sp|Q804S5|MIB1_BRARE  Ubiquitin ligase protein mib (Mind bom...    48   2e-05
sp|Q9VUX2|MIB_DROME  Ubiquitin ligase protein mind-bomb (Min...    44   2e-04
sp|Q96CA5|BIRC7_HUMAN  Baculoviral IAP repeat-containing pro...    44   4e-04
sp|Q96AX9|MIB2_HUMAN  Ubiquitin ligase protein MIB2 (Mind bo...    44   4e-04
sp|Q5ZIJ9|MIB2_CHICK  Ubiquitin ligase protein MIB2 (Mind bo...    42   0.001
sp|Q8R516|MIB2_MOUSE  Ubiquitin ligase protein MIB2 (Mind bo...    42   0.001
sp|Q68LP1|MIB2_RAT  Ubiquitin ligase protein MIB2 (Mind bomb...    42   0.001
>sp|Q86YT6|MIB1_HUMAN Ubiquitin ligase protein MIB1 (Mind bomb homolog 1) (DAPK-interacting
            protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin
            repeat domain protein 2)
          Length = 1006

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 40/159 (25%), Positives = 66/159 (41%), Gaps = 8/159 (5%)
 Frame = +2

Query: 47   IIMYLIEKGAKLDLRNNDGKTPIDCCGDDSLKIKLKNMSSEK------SQQANMKASTSE 208
            I  +L   GA L +RN  G++P+D C D +L   L     EK      S+  +M ++ SE
Sbjct: 755  IACFLAANGADLSIRNKKGQSPLDLCPDPNLCKALAKCHKEKVSGQVGSRSPSMISNDSE 814

Query: 209  LVMTKFRTISETQLATRIPNVAPVQISESVGPPVAKTXXXXXXXXXXXXXXMKDRKICII 388
              + +    S+ +  T       +       P V K                   + C++
Sbjct: 815  -TLEECMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSRTKI-----EECVV 868

Query: 389  CRDRPMNITF-GCGHM-SCDVCANNLFECHICRGPTNQK 499
            C D+   + F  CGHM +C+ CAN + +C  CR    ++
Sbjct: 869  CSDKKAAVLFQPCGHMCACENCANLMKKCVQCRAVVERR 907

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 17/40 (42%), Positives = 27/40 (67%)
 Frame = +2

Query: 362  MKDRKICIICRDRPMNITFGCGHMSCDVCANNLFECHICR 481
            +K++ +C +C DR  N+ F CGH +C +C + + EC ICR
Sbjct: 957  IKEQTMCPVCLDRLKNMIFLCGHGTCQLCGDRMSECPICR 996

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 40/175 (22%), Positives = 71/175 (40%), Gaps = 29/175 (16%)
 Frame = +2

Query: 44   EIIMYLIEKGAKLDLRNNDGKTPI-DCCGDDSLK--IKLKNMSSEKSQQANMKASTSELV 214
            +I+  L+  GAKLD+++ DG TP+ +     +L    +L++M       A  + S + L+
Sbjct: 680  QIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQDMQDVGKVDAAWEPSKNTLI 739

Query: 215  MTKFRTISETQLATRI-----PNVAPVQISESVG---------PPVAKTXXXXXXXXXXX 352
            M      +E + A  I      N A + I    G         P + K            
Sbjct: 740  MGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDLCPDPNLCKALAKCHKEKVSG 799

Query: 353  XXXMKDRKI----------CIICRDRPMNITFG-CGHM-SCDVCANNLFECHICR 481
                +   +          C++C D   +  FG CGH+ +C +C+  + +C IC+
Sbjct: 800  QVGSRSPSMISNDSETLEECMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICK 854
>sp|Q80SY4|MIB1_MOUSE Ubiquitin ligase protein MIB1 (Mind bomb homolog 1) (DAPK-interacting
            protein 1) (DIP-1)
          Length = 1006

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 40/159 (25%), Positives = 66/159 (41%), Gaps = 8/159 (5%)
 Frame = +2

Query: 47   IIMYLIEKGAKLDLRNNDGKTPIDCCGDDSLKIKLKNMSSEK------SQQANMKASTSE 208
            I  +L   GA L +RN  G++P+D C D SL   L     EK      S+  +M ++ SE
Sbjct: 755  IACFLAANGADLSIRNKKGQSPLDLCPDPSLCKALAKCHKEKVSGQVGSRSPSMISNDSE 814

Query: 209  LVMTKFRTISETQLATRIPNVAPVQISESVGPPVAKTXXXXXXXXXXXXXXMKDRKICII 388
              + +    S+ +  T       +       P V K                   + C++
Sbjct: 815  -TLEECMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSRTKI-----EECVV 868

Query: 389  CRDRPMNITF-GCGHM-SCDVCANNLFECHICRGPTNQK 499
            C D+   + F  CGHM +C+ CA+ + +C  CR    ++
Sbjct: 869  CSDKKAAVLFQPCGHMCACENCASLMKKCVQCRAVVERR 907

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 17/40 (42%), Positives = 27/40 (67%)
 Frame = +2

Query: 362  MKDRKICIICRDRPMNITFGCGHMSCDVCANNLFECHICR 481
            +K++ +C +C DR  N+ F CGH +C +C + + EC ICR
Sbjct: 957  IKEQTMCPVCLDRLKNMIFLCGHGTCQLCGDRMSECPICR 996

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 40/175 (22%), Positives = 71/175 (40%), Gaps = 29/175 (16%)
 Frame = +2

Query: 44   EIIMYLIEKGAKLDLRNNDGKTPI-DCCGDDSLK--IKLKNMSSEKSQQANMKASTSELV 214
            +I+  L+  GAKLD+++ DG TP+ +     +L    +L++M       A  + S + L+
Sbjct: 680  QIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQDMQDVGKVDAAWEPSKNTLI 739

Query: 215  MTKFRTISETQLATRI-----PNVAPVQISESVG---------PPVAKTXXXXXXXXXXX 352
            M      +E + A  I      N A + I    G         P + K            
Sbjct: 740  MGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDLCPDPSLCKALAKCHKEKVSG 799

Query: 353  XXXMKDRKI----------CIICRDRPMNITFG-CGHM-SCDVCANNLFECHICR 481
                +   +          C++C D   +  FG CGH+ +C +C+  + +C IC+
Sbjct: 800  QVGSRSPSMISNDSETLEECMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICK 854
>sp|Q6GNY1|MIB1_XENLA Ubiquitin ligase protein MIB1 (Mind bomb homolog 1)
          Length = 1011

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 17/40 (42%), Positives = 27/40 (67%)
 Frame = +2

Query: 362  MKDRKICIICRDRPMNITFGCGHMSCDVCANNLFECHICR 481
            +K++ +C +C DR  N+ F CGH +C +C + + EC ICR
Sbjct: 958  IKEQTMCPVCLDRLKNMIFMCGHGTCQLCGDRMSECPICR 997

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 36/159 (22%), Positives = 64/159 (40%), Gaps = 8/159 (5%)
 Frame = +2

Query: 47   IIMYLIEKGAKLDLRNNDGKTPIDCCGDDSLKIKLKNMSSEKSQQANMKASTSELVMTKF 226
            I  +L   GA L +RN  G++P+D C D +L   L     EKS    + + +  ++    
Sbjct: 756  IACFLAANGADLAVRNKKGQSPLDLCPDPNLCKTLAKCHKEKS-SGQVGSHSPSMINNDS 814

Query: 227  RTISETQLATRIPN------VAPVQISESVGPPVAKTXXXXXXXXXXXXXXMKDRKICII 388
             T+ E  + + +           +       P V K                   + C++
Sbjct: 815  ETLEECMVCSDLKRDTLFGPCGHIATCSLCSPRVKKCLLCKEQVQSRTKI-----EECVV 869

Query: 389  CRDRPMNITF-GCGHM-SCDVCANNLFECHICRGPTNQK 499
            C D+   + F  CGHM +C+ CA+ + +C  CR    ++
Sbjct: 870  CSDKKAAVLFQPCGHMCACENCASLMKKCVQCRAVVERR 908
>sp|Q804S5|MIB1_BRARE Ubiquitin ligase protein mib (Mind bomb protein)
          Length = 1030

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 17/40 (42%), Positives = 27/40 (67%)
 Frame = +2

Query: 362  MKDRKICIICRDRPMNITFGCGHMSCDVCANNLFECHICR 481
            +K++ +C +C DR  N+ F CGH +C +C + + EC ICR
Sbjct: 981  IKEQTMCPVCLDRLKNMIFMCGHGTCQLCGDRMSECPICR 1020

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 36/157 (22%), Positives = 63/157 (40%), Gaps = 6/157 (3%)
 Frame = +2

Query: 47   IIMYLIEKGAKLDLRNNDGKTPIDCCGDDSLKIKLKNMSSEKSQ----QANMKASTSELV 214
            I  +L   GA L +RN  G++P+D C D SL   L     EK+       +   +++   
Sbjct: 754  IACFLAANGADLTIRNKKGQSPLDLCPDPSLCKALAKCHKEKTSGQVGSRSPSLNSNNET 813

Query: 215  MTKFRTISETQLATRIPNVAPVQISESVGPPVAKTXXXXXXXXXXXXXXMKDRKICIICR 394
            + +    S+ +  T       +       P V K                   + C++C 
Sbjct: 814  LEECMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSRTKI-----EECVVCS 868

Query: 395  DRPMNITF-GCGHM-SCDVCANNLFECHICRGPTNQK 499
            D+   + F  CGHM +C+ CA+ + +C  CR    ++
Sbjct: 869  DKKAAVLFQPCGHMCACENCASLMKKCVQCRAVVERR 905
>sp|Q9VUX2|MIB_DROME Ubiquitin ligase protein mind-bomb (Mind bomb homolog) (D-mib)
          Length = 1226

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 16/40 (40%), Positives = 26/40 (65%)
 Frame = +2

Query: 362  MKDRKICIICRDRPMNITFGCGHMSCDVCANNLFECHICR 481
            +K++ +C +C DR  N+ F CGH +C +C + +  C ICR
Sbjct: 1177 IKEQTMCPVCFDRIKNMVFLCGHGTCQMCGDQIEGCPICR 1216

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 39/161 (24%), Positives = 61/161 (37%), Gaps = 16/161 (9%)
 Frame = +2

Query: 47   IIMYLIEKGAKLDLRNNDGKTPIDCCGDDSLKIKLKNMSSEK--------------SQQA 184
            I  +L   GA L L+N   +TP+D C D +L   L    +E+              S  A
Sbjct: 847  IACFLAANGADLTLKNRKQQTPLDLCPDPNLCKTLVKCYNERKTDDSELPGNVAGTSSSA 906

Query: 185  NMKASTSELVMTKFRTISETQLATRIPNVAPVQISESVGPPVAKTXXXXXXXXXXXXXXM 364
              +A++  L  +    +  + LA    +  P   S S+                      
Sbjct: 907  RARAASGSLNQSSSVNMPLSSLAAS--STFPAASSSSIFALNGIANEMSQSLHEDPPKSS 964

Query: 365  KDRKICIICRDRPMNITFG-CGHMSC-DVCANNLFECHICR 481
                 C++C D   +  F  CGH+SC + CA  + +C ICR
Sbjct: 965  ASLDECLVCSDAKRDTVFKPCGHVSCCETCAPRVKKCLICR 1005
>sp|Q96CA5|BIRC7_HUMAN Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of
           apoptosis protein) (KIAP) (Melanoma inhibitor of
           apoptosis protein) (ML-IAP) (Livin)
          Length = 298

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
 Frame = +2

Query: 362 MKDRKICIICRDRPMNITF-GCGHMSCDVCANNLFECHICRGPTNQK 499
           +++ + C +C DR ++I F  CGH+ C  CA  L  C ICR P   +
Sbjct: 246 LQEERTCKVCLDRAVSIVFVPCGHLVCAECAPGLQLCPICRAPVRSR 292
>sp|Q96AX9|MIB2_HUMAN Ubiquitin ligase protein MIB2 (Mind bomb homolog 2) (Zinc finger ZZ
            type with ankyrin repeat domain protein 1) (Skeletrophin)
            (Novelzin) (Novel zinc finger protein) (Putative
            NF-kappa-B-activating protein 002N)
          Length = 1013

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +2

Query: 362  MKDRKICIICRDRPMNITFGCGHMSCDVCANNLFECHICRGPTNQK 499
            M++R  C IC D  + + F CGH +C  C + L  C ICR P   +
Sbjct: 963  MEERITCPICIDSHIRLVFQCGHGACAPCGSALSACPICRQPIRDR 1008
>sp|Q5ZIJ9|MIB2_CHICK Ubiquitin ligase protein MIB2 (Mind bomb homolog 2)
          Length = 954

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 18/40 (45%), Positives = 23/40 (57%)
 Frame = +2

Query: 362  MKDRKICIICRDRPMNITFGCGHMSCDVCANNLFECHICR 481
            M++R  C IC D  + + F CGH SC  C+  L  C ICR
Sbjct: 904  MEERITCPICIDDQIKLVFQCGHGSCPDCSTALTVCPICR 943

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 4/155 (2%)
 Frame = +2

Query: 47   IIMYLIEKGAKLDLRNNDGKTPIDCCGDDSLKIKLKNMSSE-KSQQANMKASTSELVMTK 223
            I  YL ++GA ++  N+ GK+P+D   D  +   +K+ S + + QQ +   S     + +
Sbjct: 749  IACYLAQEGADINYANHRGKSPLDLITDGRIVQIIKDFSQKFREQQVSSDCSAITCSLRR 808

Query: 224  FRTISETQLATRIPNVA-PVQISESVGPPVAKTXXXXXXXXXXXXXXMKDRKICIICRDR 400
              T   T     + +VA P +                                C++C + 
Sbjct: 809  VHTTPNTMTNLSVSSVAVPTE--------------------------------CLVCSEL 836

Query: 401  PMNI-TFGCGH-MSCDVCANNLFECHICRGPTNQK 499
             + I  F C H + C+ C+  + +C  C+    +K
Sbjct: 837  ALLIHFFPCQHSIVCEECSRRMKKCIKCQVTITKK 871
>sp|Q8R516|MIB2_MOUSE Ubiquitin ligase protein MIB2 (Mind bomb homolog 2) (Mind bomb-2)
            (Skeletrophin) (Dystrophin-like protein) (Dyslike)
          Length = 973

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 18/46 (39%), Positives = 24/46 (52%)
 Frame = +2

Query: 362  MKDRKICIICRDRPMNITFGCGHMSCDVCANNLFECHICRGPTNQK 499
            M++R  C IC D  + + F CGH +C  C   L  C ICR P   +
Sbjct: 923  MEERITCPICIDSHIRLVFQCGHGACAPCGAALNACPICRQPIRDR 968
>sp|Q68LP1|MIB2_RAT Ubiquitin ligase protein MIB2 (Mind bomb homolog 2)
            (RBSC-skeletrophin/dystrophin-like polypeptide)
          Length = 971

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 18/46 (39%), Positives = 24/46 (52%)
 Frame = +2

Query: 362  MKDRKICIICRDRPMNITFGCGHMSCDVCANNLFECHICRGPTNQK 499
            M++R  C IC D  + + F CGH +C  C   L  C ICR P   +
Sbjct: 921  MEERITCPICIDSHIRLVFQCGHGACAPCGAALNACPICRQPIRDR 966
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,996,538
Number of Sequences: 369166
Number of extensions: 1157163
Number of successful extensions: 2937
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2779
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2934
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4699949280
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)