Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_01257
(656 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P27088|XPA_XENLA DNA-repair protein complementing XP-A c... 149 5e-36
sp|Q64267|XPA_MOUSE DNA-repair protein complementing XP-A c... 144 3e-34
sp|P23025|XPA_HUMAN DNA-repair protein complementing XP-A c... 140 2e-33
sp|P27089|XPA_CHICK DNA-repair protein complementing XP-A c... 127 3e-29
sp|P28518|XPA_DROME DNA-repair protein complementing XP-A c... 117 3e-26
sp|Q64029|XPA_CRIGR DNA-repair protein complementing XP-A c... 112 8e-25
sp|P28519|RAD14_YEAST DNA repair protein RAD14 55 1e-07
sp|Q6BU94|PRP46_DEBHA Pre-mRNA splicing factor PRP46 (Pre-m... 32 1.1
sp|P21146|ARBK1_BOVIN Beta-adrenergic receptor kinase 1 (Be... 32 1.5
sp|Q9Z934|DNLJ_CHLPN DNA ligase (Polydeoxyribonucleotide sy... 32 1.5
>sp|P27088|XPA_XENLA DNA-repair protein complementing XP-A cells homolog (Xeroderma
pigmentosum group A complementing protein homolog)
Length = 267
Score = 149 bits (377), Expect = 5e-36
Identities = 89/198 (44%), Positives = 115/198 (58%), Gaps = 5/198 (2%)
Frame = +2
Query: 77 KELSLAERATIERNRQKALLKLEKK---RRYANINDKEIISNGSIYVDSNAGFLIDKE-I 244
K LS A RA IERNRQ+AL+ + + R Y + +DS GF I++E
Sbjct: 17 KILSAAVRAKIERNRQRALMLRQARLACRPYPTGEGISTVKAPPKVIDSGGGFFIEEEEA 76
Query: 245 ESKKVKSFYAEKSKVSENQIELKCSTCSELFFDSYLMKNFDLMVCNKCRDPD-LHKLINK 421
E + V++ + V E L C C + F DSYL +FDL VC+ CRD + HKLI +
Sbjct: 77 EEQHVENVVRQPGPVLECDY-LICEECGKDFMDSYLSNHFDLAVCDSCRDAEEKHKLITR 135
Query: 422 TTAKEIYLLNDTDLNKRKPVLKFIVKPNPKNSAWGDMKLYLEAQVAARSLEIWGSXXXXX 601
T AK+ YLL D D++KR+PVLKFI+K NP N+ WGDMKLYL+AQV RSLE+WGS
Sbjct: 136 TEAKQEYLLKDCDIDKREPVLKFILKKNPHNTHWGDMKLYLKAQVIKRSLEVWGSEEALE 195
Query: 602 XXXXXXXXXIDKMKILKY 655
DKMK K+
Sbjct: 196 EAKEVRKDNRDKMKQKKF 213
>sp|Q64267|XPA_MOUSE DNA-repair protein complementing XP-A cells homolog (Xeroderma
pigmentosum group A complementing protein homolog)
Length = 272
Score = 144 bits (362), Expect = 3e-34
Identities = 81/199 (40%), Positives = 113/199 (56%), Gaps = 7/199 (3%)
Frame = +2
Query: 80 ELSLAERATIERNRQKALLKLEKK---RRY---ANINDKEIISNGSIYVDSNAGFLIDKE 241
+L A RA++ER RQ+AL+ + + R Y A + +D+ GF++++E
Sbjct: 21 QLPAAVRASVERKRQRALMLRQARLAARPYPAAAATGGVASVKAAPKMIDTKGGFILEEE 80
Query: 242 IESKKVKSFYAEKSKVSENQIELKCSTCSELFFDSYLMKNFDLMVCNKCRDPD-LHKLIN 418
E ++ + E V E + C C + F DSYLM +FDL C+ CRD D HKLI
Sbjct: 81 EEKHEIGNIVHEPGPVMEFDYTI-CEECGKEFMDSYLMNHFDLPTCDSCRDADDKHKLIT 139
Query: 419 KTTAKEIYLLNDTDLNKRKPVLKFIVKPNPKNSAWGDMKLYLEAQVAARSLEIWGSXXXX 598
KT AK+ YLL D DL KR+P L+F+VK NP++S WGDMKLYL+ QV R+LE+WGS
Sbjct: 140 KTEAKQEYLLKDCDLEKREPALRFLVKKNPRHSQWGDMKLYLKLQVVKRALEVWGSQEAL 199
Query: 599 XXXXXXXXXXIDKMKILKY 655
+KMK K+
Sbjct: 200 EDAKEVRQENREKMKQKKF 218
>sp|P23025|XPA_HUMAN DNA-repair protein complementing XP-A cells (Xeroderma pigmentosum
group A complementing protein)
Length = 273
Score = 140 bits (354), Expect = 2e-33
Identities = 82/202 (40%), Positives = 112/202 (55%), Gaps = 10/202 (4%)
Frame = +2
Query: 80 ELSLAERATIERNRQKALLKLEKKRRYANINDKEIISNGSI--------YVDSNAGFLID 235
EL + RA+IER RQ+AL+ + + + + G + +D+ GF+++
Sbjct: 19 ELPASVRASIERKRQRALMLRQARLAARPYSATAAAATGGMANVKAAPKIIDTGGGFILE 78
Query: 236 KEIESK-KVKSFYAEKSKVSENQIELKCSTCSELFFDSYLMKNFDLMVCNKCRDPD-LHK 409
+E E + K+ + V E + C C + F DSYLM +FDL C+ CRD D HK
Sbjct: 79 EEEEEEQKIGKVVHQPGPVMEFDYVI-CEECGKEFMDSYLMNHFDLPTCDNCRDADDKHK 137
Query: 410 LINKTTAKEIYLLNDTDLNKRKPVLKFIVKPNPKNSAWGDMKLYLEAQVAARSLEIWGSX 589
LI KT AK+ YLL D DL KR+P LKFIVK NP +S WGDMKLYL+ Q+ RSLE+WGS
Sbjct: 138 LITKTEAKQEYLLKDCDLEKREPPLKFIVKKNPHHSQWGDMKLYLKLQIVKRSLEVWGSQ 197
Query: 590 XXXXXXXXXXXXXIDKMKILKY 655
+KMK K+
Sbjct: 198 EALEEAKEVRQENREKMKQKKF 219
>sp|P27089|XPA_CHICK DNA-repair protein complementing XP-A cells homolog (Xeroderma
pigmentosum group A complementing protein homolog)
Length = 267
Score = 127 bits (318), Expect = 3e-29
Identities = 76/180 (42%), Positives = 103/180 (57%), Gaps = 12/180 (6%)
Frame = +2
Query: 83 LSLAERATIERNRQKALLKLEKKRRYANINDKEIISNGSIYV-DSNAGFLIDKEIESKKV 259
+S A +ERNR++AL L + R A + G D+ GF +++E E +
Sbjct: 19 ISATALARMERNRRRALA-LRQARLAARPYPQAAAGAGPPQGRDTGGGFFLEEEEEEE-- 75
Query: 260 KSFYAEKSKVSENQIE----------LKCSTCSELFFDSYLMKNFDLMVCNKCRDP-DLH 406
E+ + +E + L C C + F DSYLM++FD C+ CRD D H
Sbjct: 76 -----EQRRAAERIVHPPAPVLQFDYLICGDCGKEFMDSYLMQHFDWATCDNCRDAEDKH 130
Query: 407 KLINKTTAKEIYLLNDTDLNKRKPVLKFIVKPNPKNSAWGDMKLYLEAQVAARSLEIWGS 586
KLI +T AKE YLL D DL+KR+PVL+FIVK NP N WGDMKLYL+ QV R+LE+WG+
Sbjct: 131 KLITRTEAKEEYLLKDCDLDKREPVLRFIVKKNPHNPRWGDMKLYLKLQVIKRALEVWGN 190
>sp|P28518|XPA_DROME DNA-repair protein complementing XP-A cells homolog (Xeroderma
pigmentosum group A complementing protein homolog)
Length = 296
Score = 117 bits (292), Expect = 3e-26
Identities = 74/205 (36%), Positives = 107/205 (52%), Gaps = 32/205 (15%)
Frame = +2
Query: 68 QMNKELSLAERATIERNRQKALLKLEKKRRYANINDKEIISN------------------ 193
+ +L+ A++A IERN+ KA E K + KE+ SN
Sbjct: 15 EKKSKLTNAQKARIERNQAKAQKLREAK--LVSHPFKELASNKEGGTHPEAALSQGSSVI 72
Query: 194 ---GSIYVDSNAGFLIDKEIESKKVKSFYAEKS-----KVSENQIEL-----KCSTCSEL 334
G+ Y+DS GFL+++ + V KS + ++ I + +C C ++
Sbjct: 73 KVQGTKYIDSGGGFLLEQPVMPTGVGPAGLNKSGEEAPPILDDAIAIPVQYEECLECGDM 132
Query: 335 FFDSYLMKNFDLMVCNKCRDPD-LHKLINKTTAKEIYLLNDTDLNKRKPVLKFIVKPNPK 511
F DSYL NF VC+KCRD D + LI +T AK YLL D D +KR+P L++I + NP
Sbjct: 133 FADSYLFNNFGHSVCDKCRDKDERYALITRTEAKAEYLLKDCDFDKREPKLRYISRKNPH 192
Query: 512 NSAWGDMKLYLEAQVAARSLEIWGS 586
N WG+MKLYL Q+ R+LE+WGS
Sbjct: 193 NVRWGEMKLYLHLQIHQRALEVWGS 217
>sp|Q64029|XPA_CRIGR DNA-repair protein complementing XP-A cells homolog (Xeroderma
pigmentosum group A complementing protein homolog)
Length = 97
Score = 112 bits (280), Expect = 8e-25
Identities = 53/82 (64%), Positives = 63/82 (76%), Gaps = 1/82 (1%)
Frame = +2
Query: 344 SYLMKNFDLMVCNKCRDPD-LHKLINKTTAKEIYLLNDTDLNKRKPVLKFIVKPNPKNSA 520
SYLM +FDL C+ CRD D HKLI KT AK+ YLL D DL KR+P L+FIVK NP++S
Sbjct: 1 SYLMNHFDLPTCDSCRDADDKHKLITKTEAKQEYLLKDCDLEKREPALRFIVKKNPRHSQ 60
Query: 521 WGDMKLYLEAQVAARSLEIWGS 586
WGDMKLYL+ QV R+LE+WGS
Sbjct: 61 WGDMKLYLKLQVVKRALEVWGS 82
>sp|P28519|RAD14_YEAST DNA repair protein RAD14
Length = 371
Score = 55.5 bits (132), Expect = 1e-07
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 16/155 (10%)
Frame = +2
Query: 167 INDKEIISNGSIYVDSNAGFLIDKEIESKKVKSFYAEKSKVSENQIEL------------ 310
IN K+ + N D + E SKK K+ K + E ++
Sbjct: 133 INPKDKLPNSDFTDDQE----FESEFGSKKQKTLQDWKKEQLERKMLYENAPPPEHISKA 188
Query: 311 -KCSTCS-ELFFDSYLMKNFDLMVCNKC--RDPDLHKLINKTTAKEIYLLNDTDLNKRKP 478
KC C + D L F L VC +C P+ + L+ KT KE Y L D +LN +
Sbjct: 189 PKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELND-ED 247
Query: 479 VLKFIVKPNPKNSAWGDMKLYLEAQVAARSLEIWG 583
+ + KPNP + + M+L++ +V A + + WG
Sbjct: 248 LFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWG 282
>sp|Q6BU94|PRP46_DEBHA Pre-mRNA splicing factor PRP46 (Pre-mRNA processing protein 46)
Length = 417
Score = 32.3 bits (72), Expect = 1.1
Identities = 17/51 (33%), Positives = 27/51 (52%)
Frame = +2
Query: 359 NFDLMVCNKCRDPDLHKLINKTTAKEIYLLNDTDLNKRKPVLKFIVKPNPK 511
NF++++ C + L +IN + KE++ +NDTDL L V N K
Sbjct: 2 NFNIIIKIICENIQLAPIINMVSYKELFNINDTDLIVPSDTLSEAVYDNSK 52
>sp|P21146|ARBK1_BOVIN Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (G-protein coupled
receptor kinase 2)
Length = 689
Score = 32.0 bits (71), Expect = 1.5
Identities = 16/46 (34%), Positives = 26/46 (56%)
Frame = +2
Query: 245 ESKKVKSFYAEKSKVSENQIELKCSTCSELFFDSYLMKNFDLMVCN 382
E+K + FY E K + + E + CS FD+Y+MK +L+ C+
Sbjct: 78 EAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMK--ELLACS 121
>sp|Q9Z934|DNLJ_CHLPN DNA ligase (Polydeoxyribonucleotide synthase [NAD+])
Length = 662
Score = 32.0 bits (71), Expect = 1.5
Identities = 15/39 (38%), Positives = 25/39 (64%)
Frame = +2
Query: 461 LNKRKPVLKFIVKPNPKNSAWGDMKLYLEAQVAARSLEI 577
+N+++ L+ + NP+N+A G +KL +VA R LEI
Sbjct: 183 INEKQQQLEKTIFANPRNAAGGTLKLLSPQEVAKRKLEI 221
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,461,794
Number of Sequences: 369166
Number of extensions: 1133776
Number of successful extensions: 3709
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3583
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3697
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5462583840
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)