Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_01217
(349 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8MKI5|CASP3_CANFA Caspase-3 precursor (CASP-3) [Contain... 82 5e-16
sp|P42574|CASP3_HUMAN Caspase-3 precursor (CASP-3) (Apopain... 80 2e-15
sp|Q5IS54|CASP3_PANTR Caspase-3 precursor (CASP-3) [Contain... 80 2e-15
sp|Q95ND5|CASP3_PIG Caspase-3 precursor (CASP-3) [Contains:... 79 2e-15
sp|Q8MJC3|CASP3_RABIT Caspase-3 precursor (CASP-3) (Apopain... 79 2e-15
sp|Q8MJU1|CASP3_FELCA Caspase-3 precursor (CASP-3) [Contain... 79 4e-15
sp|P55213|CASP3_RAT Caspase-3 precursor (CASP-3) (Apopain) ... 78 7e-15
sp|P70677|CASP3_MOUSE Caspase-3 precursor (CASP-3) (Apopain... 77 2e-14
sp|P55210|CASP7_HUMAN Caspase-7 precursor (CASP-7) (ICE-lik... 75 4e-14
sp|Q60431|CASP3_CRILO Caspase-3 precursor (CASP-3) (Apopain... 75 6e-14
>sp|Q8MKI5|CASP3_CANFA Caspase-3 precursor (CASP-3) [Contains: Caspase-3 p17 subunit;
Caspase-3 p12 subunit]
Length = 277
Score = 81.6 bits (200), Expect = 5e-16
Identities = 40/86 (46%), Positives = 51/86 (59%)
Frame = -3
Query: 347 EADVLIGYSTVPGYFSWRNSSNGSWYIQALCAEIEKYAKTEDVLHILXXXXXXXXXNFSS 168
EAD L YST PGY+SWRNS +GSW+IQ+LCA ++ YA + +HIL F S
Sbjct: 190 EADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKLYAHKLEFMHILTRVNRKVATEFES 249
Query: 167 NTGDIKSHGMIQIPSFTCMLRKKTWL 90
+ D HG QIP ML K+ +L
Sbjct: 250 FSLDSAFHGKKQIPCIVSMLTKELYL 275
>sp|P42574|CASP3_HUMAN Caspase-3 precursor (CASP-3) (Apopain) (Cysteine protease CPP32)
(Yama protein) (CPP-32) (SREBP cleavage activity 1)
(SCA-1) [Contains: Caspase-3 p17 subunit; Caspase-3 p12
subunit]
Length = 277
Score = 79.7 bits (195), Expect = 2e-15
Identities = 38/85 (44%), Positives = 50/85 (58%)
Frame = -3
Query: 347 EADVLIGYSTVPGYFSWRNSSNGSWYIQALCAEIEKYAKTEDVLHILXXXXXXXXXNFSS 168
EAD L YST PGY+SWRNS +GSW+IQ+LCA +++YA + +HIL F S
Sbjct: 190 EADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFES 249
Query: 167 NTGDIKSHGMIQIPSFTCMLRKKTW 93
+ D H QIP ML K+ +
Sbjct: 250 FSFDATFHAKKQIPCIVSMLTKELY 274
>sp|Q5IS54|CASP3_PANTR Caspase-3 precursor (CASP-3) [Contains: Caspase-3 p17 subunit;
Caspase-3 p12 subunit]
Length = 277
Score = 79.7 bits (195), Expect = 2e-15
Identities = 38/85 (44%), Positives = 50/85 (58%)
Frame = -3
Query: 347 EADVLIGYSTVPGYFSWRNSSNGSWYIQALCAEIEKYAKTEDVLHILXXXXXXXXXNFSS 168
EAD L YST PGY+SWRNS +GSW+IQ+LCA +++YA + +HIL F S
Sbjct: 190 EADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFES 249
Query: 167 NTGDIKSHGMIQIPSFTCMLRKKTW 93
+ D H QIP ML K+ +
Sbjct: 250 FSFDATFHAKKQIPCIVSMLTKELY 274
>sp|Q95ND5|CASP3_PIG Caspase-3 precursor (CASP-3) [Contains: Caspase-3 p17 subunit;
Caspase-3 p12 subunit]
Length = 277
Score = 79.3 bits (194), Expect = 2e-15
Identities = 37/85 (43%), Positives = 50/85 (58%)
Frame = -3
Query: 347 EADVLIGYSTVPGYFSWRNSSNGSWYIQALCAEIEKYAKTEDVLHILXXXXXXXXXNFSS 168
EAD L YST PGY+SWRNS +GSW+IQ+LCA +++Y +++HIL F S
Sbjct: 190 EADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAALKQYVHKLELMHILTRVNRKVAVEFES 249
Query: 167 NTGDIKSHGMIQIPSFTCMLRKKTW 93
+ D H QIP ML K+ +
Sbjct: 250 FSTDSTFHAKKQIPCIVSMLTKELY 274
>sp|Q8MJC3|CASP3_RABIT Caspase-3 precursor (CASP-3) (Apopain) (Cysteine protease CPP32)
[Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit]
Length = 277
Score = 79.3 bits (194), Expect = 2e-15
Identities = 38/85 (44%), Positives = 49/85 (57%)
Frame = -3
Query: 347 EADVLIGYSTVPGYFSWRNSSNGSWYIQALCAEIEKYAKTEDVLHILXXXXXXXXXNFSS 168
EAD L YST PGY+SWRNS GSW+IQ+LCA +++YA + +HIL F S
Sbjct: 190 EADFLYAYSTAPGYYSWRNSEEGSWFIQSLCAMLKEYAHKLEFMHILTRVNRKVATEFES 249
Query: 167 NTGDIKSHGMIQIPSFTCMLRKKTW 93
+ D H QIP ML K+ +
Sbjct: 250 YSLDATFHAKKQIPCIVSMLTKELY 274
>sp|Q8MJU1|CASP3_FELCA Caspase-3 precursor (CASP-3) [Contains: Caspase-3 p17 subunit;
Caspase-3 p12 subunit]
Length = 277
Score = 78.6 bits (192), Expect = 4e-15
Identities = 38/85 (44%), Positives = 49/85 (57%)
Frame = -3
Query: 347 EADVLIGYSTVPGYFSWRNSSNGSWYIQALCAEIEKYAKTEDVLHILXXXXXXXXXNFSS 168
EAD L YST PGY+SWRNS +GSW+IQ+LC+ + YA + +HIL F S
Sbjct: 190 EADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLRLYAHELEFMHILTRVNRKVATEFES 249
Query: 167 NTGDIKSHGMIQIPSFTCMLRKKTW 93
+ D HG QIP ML K+ +
Sbjct: 250 FSLDSAFHGKKQIPCIVSMLTKELY 274
>sp|P55213|CASP3_RAT Caspase-3 precursor (CASP-3) (Apopain) (Cysteine protease CPP32)
(Yama protein) (CPP-32) (SREBP cleavage activity 1)
(SCA-1) (LICE) (IRP) [Contains: Caspase-3 p17 subunit;
Caspase-3 p12 subunit]
Length = 277
Score = 77.8 bits (190), Expect = 7e-15
Identities = 38/85 (44%), Positives = 49/85 (57%)
Frame = -3
Query: 347 EADVLIGYSTVPGYFSWRNSSNGSWYIQALCAEIEKYAKTEDVLHILXXXXXXXXXNFSS 168
EAD L YST PGY+SWRNS +GSW+IQ+LCA ++ YA + +HIL F S
Sbjct: 190 EADFLYAYSTAPGYYSWRNSRDGSWFIQSLCAMLKLYAHKLEFMHILTRVNRKVATEFES 249
Query: 167 NTGDIKSHGMIQIPSFTCMLRKKTW 93
+ D H QIP ML K+ +
Sbjct: 250 FSLDATFHAKKQIPCIVSMLTKELY 274
>sp|P70677|CASP3_MOUSE Caspase-3 precursor (CASP-3) (Apopain) (Cysteine protease CPP32)
(Yama protein) (CPP-32) (SREBP cleavage activity 1)
(SCA-1) (LICE) [Contains: Caspase-3 p17 subunit;
Caspase-3 p12 subunit]
Length = 277
Score = 76.6 bits (187), Expect = 2e-14
Identities = 37/85 (43%), Positives = 49/85 (57%)
Frame = -3
Query: 347 EADVLIGYSTVPGYFSWRNSSNGSWYIQALCAEIEKYAKTEDVLHILXXXXXXXXXNFSS 168
EAD L YST PGY+SWRNS +GSW+IQ+LC+ ++ YA + +HIL F S
Sbjct: 190 EADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLKLYAHKLEFMHILTRVNRKVATEFES 249
Query: 167 NTGDIKSHGMIQIPSFTCMLRKKTW 93
+ D H QIP ML K+ +
Sbjct: 250 FSLDSTFHAKKQIPCIVSMLTKELY 274
>sp|P55210|CASP7_HUMAN Caspase-7 precursor (CASP-7) (ICE-like apoptotic protease 3)
(ICE-LAP3) (Apoptotic protease Mch-3) (CMH-1) [Contains:
Caspase-7 subunit p20; Caspase-7 subunit p11]
Length = 303
Score = 75.5 bits (184), Expect = 4e-14
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = -3
Query: 347 EADVLIGYSTVPGYFSWRNSSNGSWYIQALCAEIEKYAKTEDVLHILXXXXXXXXXNFSS 168
EAD L YSTVPGY+SWR+ GSW++QALC+ +E++ K +++ IL +F S
Sbjct: 216 EADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFES 275
Query: 167 NTGDIKSHGMIQIPSFTCMLRKKTW 93
+ D H QIP ML K+ +
Sbjct: 276 QSDDPHFHEKKQIPCVVSMLTKELY 300
>sp|Q60431|CASP3_CRILO Caspase-3 precursor (CASP-3) (Apopain) (Cysteine protease CPP32)
(Yama protein) (CPP-32) (SREBP cleavage activity 1)
(SCA-1) [Contains: Caspase-3 p17 subunit; Caspase-3 p12
subunit]
Length = 277
Score = 74.7 bits (182), Expect = 6e-14
Identities = 36/85 (42%), Positives = 48/85 (56%)
Frame = -3
Query: 347 EADVLIGYSTVPGYFSWRNSSNGSWYIQALCAEIEKYAKTEDVLHILXXXXXXXXXNFSS 168
EAD L YST PGY+SWRN +GSW+IQ+LC+ ++ YA + +HIL F S
Sbjct: 190 EADFLYAYSTAPGYYSWRNPKDGSWFIQSLCSMLKLYAHKLEFMHILTRVNRKVATEFES 249
Query: 167 NTGDIKSHGMIQIPSFTCMLRKKTW 93
+ D H QIP ML K+ +
Sbjct: 250 FSLDSTFHAKKQIPCIVSMLTKELY 274
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,037,954
Number of Sequences: 369166
Number of extensions: 710038
Number of successful extensions: 1535
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1529
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1535
length of database: 68,354,980
effective HSP length: 83
effective length of database: 53,021,975
effective search space used: 1696703200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)