Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_P19
(822 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q25464|FP2_MYTGA Adhesive plaque matrix protein 2 precur... 57 5e-08
sp|P07207|NOTCH_DROME Neurogenic locus Notch protein precursor 55 2e-07
sp|Q14520|HABP2_HUMAN Hyaluronan-binding protein 2 precurso... 53 1e-06
sp|Q61982|NOTC3_MOUSE Neurogenic locus notch homolog protei... 53 1e-06
sp|Q9R172|NOTC3_RAT Neurogenic locus notch homolog protein ... 53 1e-06
sp|P31695|NOTC4_MOUSE Neurogenic locus notch homolog protei... 53 1e-06
sp|P24014|SLIT_DROME Slit protein precursor [Contains: Slit... 52 2e-06
sp|Q9UM47|NOTC3_HUMAN Neurogenic locus notch homolog protei... 52 2e-06
sp|P21783|NOTCH_XENLA Neurogenic locus notch protein homolo... 52 3e-06
sp|O57409|DLLB_BRARE Delta-like protein B precursor (DeltaB... 51 3e-06
>sp|Q25464|FP2_MYTGA Adhesive plaque matrix protein 2 precursor (Foot protein 2) (MGFP2)
(MGFP-2)
Length = 473
Score = 57.4 bits (137), Expect = 5e-08
Identities = 28/84 (33%), Positives = 41/84 (48%)
Frame = +1
Query: 16 QCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
QC+N C+ G T++C C + G+LCEK GKC G Y C+CS
Sbjct: 90 QCKNKSRCVPVGKTFKCVCRNGNFGRLCEK-NVCSPNPCKNNGKC--SPLGKTGYKCTCS 146
Query: 196 EGFTGEKCDLRIYQPCICPKNMKC 267
G+TG +C++ +P C +C
Sbjct: 147 GGYTGPRCEVHACKPNPCKNKGRC 170
Score = 55.1 bits (131), Expect = 2e-07
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Frame = +1
Query: 19 CQNNGYCINNGLT-YECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
C+N G C +G T Y+C+C+D Y G C++ G C GD Y+C C
Sbjct: 164 CKNKGRCFPDGKTGYKCRCVDGYSGPTCQENACKPNPCSNG-GTCSADKFGD--YSCECR 220
Query: 196 EGFTGEKCDLRIYQPCICPKNMKCNYSESG 285
G+ G +C+ + P C C+ SG
Sbjct: 221 PGYFGPECERYVCAPNPCKNGGICSSDGSG 250
Score = 55.1 bits (131), Expect = 2e-07
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 3/97 (3%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+N+G C+N G +Y C C Y G C + G+C+ N D + C C
Sbjct: 275 CKNSGRCVNKGSSYNCICKGGYSGPTCGE-NVCKPNPCQNRGRCYPDNSDDG-FKCRCVG 332
Query: 199 GFTGEKCDLRIYQPC---ICPKNMKCNYSESGALFSC 300
G+ G C+ + PC C KCNY +G +++C
Sbjct: 333 GYKGPTCEDK-PNPCNTKPCKNGGKCNY--NGKIYTC 366
Score = 53.9 bits (128), Expect = 5e-07
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
Frame = +1
Query: 19 CQNNGYCI--NNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACS 189
CQN G C N+ ++C+C+ Y G CE K GKC N+ K+Y C
Sbjct: 311 CQNRGRCYPDNSDDGFKCRCVGGYKGPTCEDKPNPCNTKPCKNGGKC---NYNGKIYTCK 367
Query: 190 CSEGFTGEKCDLRIYQPCICPKNMKC 267
C+ G+ G C + Y+P C + C
Sbjct: 368 CAYGWRGRHCTDKAYKPNPCVVSKPC 393
Score = 52.0 bits (123), Expect = 2e-06
Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 4/74 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE----KXXXXXXXXXXXXGKCFVQNHGDKLYAC 186
C+N G CI NG Y CKC Y G+ C K GKC + +G Y C
Sbjct: 393 CKNRGKCIWNGKAYRCKCAYGYGGRHCTKKSYKKNPCASRPCKNRGKCTDKGNG---YVC 449
Query: 187 SCSEGFTGEKCDLR 228
C+ G++G C L+
Sbjct: 450 KCARGYSGRYCSLK 463
Score = 44.3 bits (103), Expect = 4e-04
Identities = 23/84 (27%), Positives = 31/84 (36%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+ NG C G +Y+C C Y G C +C K + C C
Sbjct: 54 CKYNGVCKPRGGSYKCFCKGGYYGYNCNLKNACKPNQCKNKSRCVPVG---KTFKCVCRN 110
Query: 199 GFTGEKCDLRIYQPCICPKNMKCN 270
G G C+ + P C N KC+
Sbjct: 111 GNFGRLCEKNVCSPNPCKNNGKCS 134
>sp|P07207|NOTCH_DROME Neurogenic locus Notch protein precursor
Length = 2703
Score = 55.5 bits (132), Expect = 2e-07
Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 4/144 (2%)
Frame = +1
Query: 7 SNIQCQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYA 183
S+ CQ+ G C + + C+C+ Y G+ CE G C + +G Y
Sbjct: 796 SSNPCQHGGTCYDKLNAFSCQCMPGYTGQKCETNIDDCVTNPCGNGGTCIDKVNG---YK 852
Query: 184 CSCSEGFTGEKCDLRIYQPCI---CPKNMKCNYSESGALFSCTSENEADSSNPKSDYSNR 354
C C FTG C+ ++ PC C KC S + FSCT K Y+ R
Sbjct: 853 CVCKVPFTGRDCESKM-DPCASNRCKNEAKCTPSSNFLDFSCTC---------KLGYTGR 902
Query: 355 KVKQNWKDVSLSTTIVAAVGCMTI 426
++ + SLS+ C+ +
Sbjct: 903 YCDEDIDECSLSSPCRNGASCLNV 926
Score = 54.7 bits (130), Expect = 3e-07
Identities = 26/67 (38%), Positives = 31/67 (46%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
CQN G C +NGL+YECKC + GK CE+ G + D Y C C
Sbjct: 264 CQNGGICRSNGLSYECKCPKGFEGKNCEQNYDDCLGHLCQNGGTCIDGISD--YTCRCPP 321
Query: 199 GFTGEKC 219
FTG C
Sbjct: 322 NFTGRFC 328
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 5/80 (6%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
CQN G C+++ T+ C C+ + G CE G C + +G K CSC+
Sbjct: 497 CQNEGSCLDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCLNDGTCHDKINGFK---CSCA 553
Query: 196 EGFTGEKCDLRI----YQPC 243
GFTG +C + I QPC
Sbjct: 554 LGFTGARCQINIDDCQSQPC 573
Score = 46.6 bits (109), Expect = 8e-05
Identities = 29/101 (28%), Positives = 41/101 (40%), Gaps = 7/101 (6%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKL-----YA 183
C++NG C+N +Y C C + G CE QN G L +
Sbjct: 459 CEHNGICVNTPGSYRCNCSQGFTGPRCETNINECESHP-------CQNEGSCLDDPGTFR 511
Query: 184 CSCSEGFTGEKCDLRI--YQPCICPKNMKCNYSESGALFSC 300
C C GFTG +C++ I Q C + C+ +G SC
Sbjct: 512 CVCMPGFTGTQCEIDIDECQSNPCLNDGTCHDKINGFKCSC 552
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 3/82 (3%)
Frame = +1
Query: 7 SNIQCQNNGYCIN--NGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQ-NHGDKL 177
+++ CQN G C+ NG TY C C Y+G CE G C V +G
Sbjct: 63 TSVGCQNGGTCVTQLNGKTY-CACDSHYVGDYCEHRNPCNSMRCQNGGTCQVTFRNGRPG 121
Query: 178 YACSCSEGFTGEKCDLRIYQPC 243
+C C GF C++ + C
Sbjct: 122 ISCKCPLGFDESLCEIAVPNAC 143
Score = 45.4 bits (106), Expect = 2e-04
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
C N G CI+ Y C CL Y G C+ K C QN+ Y C C
Sbjct: 1031 CLNGGSCIDGINGYNCSCLAGYSGANCQYKLNKCDSNPCLNGATCHEQNNE---YTCHCP 1087
Query: 196 EGFTGEKC 219
GFTG++C
Sbjct: 1088 SGFTGKQC 1095
Score = 45.4 bits (106), Expect = 2e-04
Identities = 23/75 (30%), Positives = 29/75 (38%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
CQN G C + C C + + GK CE G C V + G Y C C
Sbjct: 1346 CQNGGNCNIRQSGHHCICNNGFYGKNCELSGQDCDSNPCRVGNCVVADEGFG-YRCECPR 1404
Query: 199 GFTGEKCDLRIYQPC 243
G GE C++ C
Sbjct: 1405 GTLGEHCEIDTLDEC 1419
Score = 43.9 bits (102), Expect = 5e-04
Identities = 23/72 (31%), Positives = 30/72 (41%)
Frame = +1
Query: 16 QCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
Q NNG C + G ++ C C Y G C+K G G Y C C
Sbjct: 1153 QLCNNGTCKDYGNSHVCYCSQGYAGSYCQKEIDECQSQPCQNGGTCRDLIG--AYECQCR 1210
Query: 196 EGFTGEKCDLRI 231
+GF G+ C+L I
Sbjct: 1211 QGFQGQNCELNI 1222
Score = 43.5 bits (101), Expect = 7e-04
Identities = 27/89 (30%), Positives = 34/89 (38%), Gaps = 1/89 (1%)
Frame = +1
Query: 10 NIQCQNNGYCINNGLT-YECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYAC 186
++ C N G C L Y C C + Y G+ CE C G + C
Sbjct: 145 HVTCLNGGTCQLKTLEEYTCACANGYTGERCETKNLCASSPCRNGATCTALA-GSSSFTC 203
Query: 187 SCSEGFTGEKCDLRIYQPCICPKNMKCNY 273
SC GFTG+ C I + C N C Y
Sbjct: 204 SCPPGFTGDTCSYDIEE---CQSN-PCKY 228
Score = 43.5 bits (101), Expect = 7e-04
Identities = 28/97 (28%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
CQ +G+C + +Y C+C GK CE G + G Y C C
Sbjct: 648 CQFDGHCQDRVGSYYCQCQAGTSGKNCEVNVNECHSNPCNNGATCID--GINSYKCQCVP 705
Query: 199 GFTGEKCDLRIYQPCI---CPKNMKCNYSESGALFSC 300
GFTG+ C+ + CI C N C +G C
Sbjct: 706 GFTGQHCEKNV-DECISSPCANNGVCIDQVNGYKCEC 741
Score = 43.5 bits (101), Expect = 7e-04
Identities = 22/71 (30%), Positives = 30/71 (42%)
Frame = +1
Query: 7 SNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYAC 186
++ CQN G C++ Y C C+D + GK CE G Q Y C
Sbjct: 951 ASFPCQNGGTCLDGIGDYSCLCVDGFDGKHCETDINECLSQPCQNGATCSQYVNS--YTC 1008
Query: 187 SCSEGFTGEKC 219
+C GF+G C
Sbjct: 1009 TCPLGFSGINC 1019
Score = 43.1 bits (100), Expect = 0.001
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
C+ G C+N +Y+C C Y GK C+ K G C Y C C
Sbjct: 226 CKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKPCSPSPCQNGGIC---RSNGLSYECKCP 282
Query: 196 EGFTGEKCDLRIYQPCI 246
+GF G+ C+ + Y C+
Sbjct: 283 KGFEGKNCE-QNYDDCL 298
Score = 43.1 bits (100), Expect = 0.001
Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 4/79 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+N C+N +Y C C Y G+ C G + GD Y+C C +
Sbjct: 917 CRNGASCLNVPGSYRCLCTKGYEGRDCAINTDDCASFPCQNGGTCLDGIGD--YSCLCVD 974
Query: 199 GFTGEKCDLRI----YQPC 243
GF G+ C+ I QPC
Sbjct: 975 GFDGKHCETDINECLSQPC 993
Score = 42.4 bits (98), Expect = 0.002
Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 4/79 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+N G C ++ Y C+C Y G CE GKC + + C C
Sbjct: 573 CRNRGICHDSIAGYSCECPPGYTGTSCEININDCDSNPCHRGKCIDDVNS---FKCLCDP 629
Query: 199 GFTGEKCDLRIYQ----PC 243
G+TG C +I + PC
Sbjct: 630 GYTGYICQKQINECESNPC 648
Score = 40.8 bits (94), Expect = 0.005
Identities = 24/81 (29%), Positives = 33/81 (40%), Gaps = 5/81 (6%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEK-XXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
C N CI+ +Y+C+C+ + G+ CEK G C Q +G Y C C
Sbjct: 686 CNNGATCIDGINSYKCQCVPGFTGQHCEKNVDECISSPCANNGVCIDQVNG---YKCECP 742
Query: 196 EGFTGEKC----DLRIYQPCI 246
GF C D PC+
Sbjct: 743 RGFYDAHCLSDVDECASNPCV 763
Score = 40.0 bits (92), Expect = 0.008
Identities = 24/98 (24%), Positives = 34/98 (34%), Gaps = 2/98 (2%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C NNG CI+ +EC C ++G CE Y C+C
Sbjct: 1268 CHNNGSCIDRVGGFECVCQPGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCRP 1327
Query: 199 GFTGEKCDLRI--YQPCICPKNMKCNYSESGALFSCTS 306
G G C+ ++ C CN +SG C +
Sbjct: 1328 GHMGRHCEHKVDFCAQSPCQNGGNCNIRQSGHHCICNN 1365
Score = 39.7 bits (91), Expect = 0.010
Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 3/70 (4%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE---KXXXXXXXXXXXXGKCFVQNHGDKLYACS 189
CQN G CI+ Y C+C ++ G+ C+ G HG Y+C
Sbjct: 302 CQNGGTCIDGISDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGATCTNTHGS--YSCI 359
Query: 190 CSEGFTGEKC 219
C G+ G C
Sbjct: 360 CVNGWAGLDC 369
Score = 39.7 bits (91), Expect = 0.010
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 1/71 (1%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXG-KCFVQNHGDKLYACSCS 195
C N C Y C C + GK C + G C H ++C CS
Sbjct: 1069 CLNGATCHEQNNEYTCHCPSGFTGKQCSEYVDWCGQSPCENGATCSQMKH---QFSCKCS 1125
Query: 196 EGFTGEKCDLR 228
G+TG+ CD++
Sbjct: 1126 AGWTGKLCDVQ 1136
Score = 39.3 bits (90), Expect = 0.013
Identities = 28/122 (22%), Positives = 44/122 (36%), Gaps = 5/122 (4%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
CQN G C + + + C C +G +CE G C + G + C C
Sbjct: 1230 CQNGGTCHDRVMNFSCSCPPGTMGIICEINKDDCKPGACHNNGSCIDRVGG---FECVCQ 1286
Query: 196 EGFTGEKCDLRIYQ----PCICPKNMKCNYSESGALFSCTSENEADSSNPKSDYSNRKVK 363
GF G +C+ I + PC + C + +C + K D+ +
Sbjct: 1287 PGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCRPGHMGRHCEHKVDFCAQSPC 1346
Query: 364 QN 369
QN
Sbjct: 1347 QN 1348
Score = 38.1 bits (87), Expect = 0.029
Identities = 24/86 (27%), Positives = 32/86 (37%), Gaps = 11/86 (12%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQ--NHG-----DKL 177
C+N C + CKC + GKLC+ G Q N+G
Sbjct: 1107 CENGATCSQMKHQFSCKCSAGWTGKLCDVQTISCQDAADRKGLSLRQLCNNGTCKDYGNS 1166
Query: 178 YACSCSEGFTGEKCDLRI----YQPC 243
+ C CS+G+ G C I QPC
Sbjct: 1167 HVCYCSQGYAGSYCQKEIDECQSQPC 1192
Score = 35.0 bits (79), Expect = 0.25
Identities = 31/115 (26%), Positives = 43/115 (37%), Gaps = 13/115 (11%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C CI+ ++ C+C G LC C YACSC+
Sbjct: 381 CFYGATCIDGVGSFYCQCTKGKTGLLCHLDDACTSNPCHADAICDTSPINGS-YACSCAT 439
Query: 199 GFTGEKCDLRIYQ-----PC----IC---PKNMKCNYSESGALFSC-TSENEADS 324
G+ G C I + PC IC P + +CN S+ C T+ NE +S
Sbjct: 440 GYKGVDCSEDIDECDQGSPCEHNGICVNTPGSYRCNCSQGFTGPRCETNINECES 494
Score = 33.9 bits (76), Expect = 0.55
Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 4/80 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
CQN C +Y C C + G C+ G + G Y CSC
Sbjct: 993 CQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESSCLNGGSCID--GINGYNCSCLA 1050
Query: 199 GFTGEKCDLRIYQ----PCI 246
G++G C ++ + PC+
Sbjct: 1051 GYSGANCQYKLNKCDSNPCL 1070
>sp|Q14520|HABP2_HUMAN Hyaluronan-binding protein 2 precursor (Plasma hyaluronan-binding
protein) (Hepatocyte growth factor activator-like
protein) (Factor VII-activating protease) (Factor
seven-activating protease) (FSAP) [Contains:
Hyaluronan-binding protein 2 50 kDa heavy chain;
Hyaluronan-binding protein 2 50 kDa heavy chain
alternate form; Hyaluronan-binding protein 2 27 kDa
light chain; Hyaluronan-binding protein 2 27 kDa light
chain alternate form]
Length = 560
Score = 52.8 bits (125), Expect = 1e-06
Identities = 24/101 (23%), Positives = 43/101 (42%), Gaps = 2/101 (1%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C++ G C+ +G T+ C CL + G C+K G+C + Y C C
Sbjct: 82 CEHGGDCLVHGSTFTCSCLAPFSGNKCQKVQNTCKDNPCGRGQCLI-TQSPPYYRCVCKH 140
Query: 199 GFTGEKCD--LRIYQPCICPKNMKCNYSESGALFSCTSENE 315
+TG C + + +P C C+ + + F+C ++
Sbjct: 141 PYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQ 181
>sp|Q61982|NOTC3_MOUSE Neurogenic locus notch homolog protein 3 precursor (Notch 3)
[Contains: Notch 3 extracellular truncation; Notch 3
intracellular domain]
Length = 2318
Score = 52.8 bits (125), Expect = 1e-06
Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+N C++ YEC+C + + G LCE+ G+C G ++C+C+
Sbjct: 517 CRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRCV---DGIASFSCACAP 573
Query: 199 GFTGEKCDLRI----YQPC 243
G+TG +C+ ++ QPC
Sbjct: 574 GYTGIRCESQVDECRSQPC 592
Score = 47.0 bits (110), Expect = 6e-05
Identities = 22/75 (29%), Positives = 34/75 (45%)
Frame = +1
Query: 7 SNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYAC 186
S C++ G C+N ++ C+C Y G LCE G Q+ D Y C
Sbjct: 165 SGTTCRHGGTCLNTPGSFRCQCPLGYTGLLCENPVVPCAPSPCRNGGTCRQS-SDVTYDC 223
Query: 187 SCSEGFTGEKCDLRI 231
+C GF G+ C++ +
Sbjct: 224 ACLPGFEGQNCEVNV 238
Score = 46.6 bits (109), Expect = 8e-05
Identities = 31/112 (27%), Positives = 45/112 (40%), Gaps = 12/112 (10%)
Frame = +1
Query: 1 ISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKL- 177
+ S +QC +NG C++ + C C Y G CE G C + D L
Sbjct: 1171 LDSGVQCLHNGTCVDLVGGFRCNCPPGYTGLHCE-----ADINECRPGACHAAHTRDCLQ 1225
Query: 178 -----YACSCSEGFTGEKCDLRIYQPC---ICPKNMKCNYS---ESGALFSC 300
+ C C GFTG +C + + PC C +C +S G F+C
Sbjct: 1226 DPGGHFRCVCHPGFTGPRCQIAL-SPCESQPCQHGGQCRHSLGRGGGLTFTC 1276
Score = 45.4 bits (106), Expect = 2e-04
Identities = 20/67 (29%), Positives = 30/67 (44%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
CQ G C ++G+ + C C + G CE G C ++ D+L CSC
Sbjct: 744 CQAGGTCTSDGIGFRCTCAPGFQGHQCEVLSPCTPSLCEHGGHC--ESDPDRLTVCSCPP 801
Query: 199 GFTGEKC 219
G+ G +C
Sbjct: 802 GWQGPRC 808
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
Frame = +1
Query: 16 QCQNNGYCINNGLTYECKCLDSYIGKLCEK---XXXXXXXXXXXXGKCFVQNHGDKLYAC 186
+C N G C++ TY C+C + G+ C + G CF G ++C
Sbjct: 245 RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNLLGG---HSC 301
Query: 187 SCSEGFTGEKCDLRI 231
C G+TGE C I
Sbjct: 302 VCVNGWTGESCSQNI 316
Score = 40.4 bits (93), Expect = 0.006
Identities = 27/97 (27%), Positives = 38/97 (39%), Gaps = 2/97 (2%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C++ G C+N ++ C+C Y G CE + G + C C
Sbjct: 403 CEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ--FTCICMA 460
Query: 199 GFTGEKCDLRI--YQPCICPKNMKCNYSESGALFSCT 303
GFTG C++ I Q C C +G FSCT
Sbjct: 461 GFTGTYCEVDIDECQSSPCVNGGVCKDRVNG--FSCT 495
Score = 40.4 bits (93), Expect = 0.006
Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 1/72 (1%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXG-KCFVQNHGDKLYACSCS 195
C N G C + + C C + G +C+ G KC Q G Y C C+
Sbjct: 479 CVNGGVCKDRVNGFSCTCPSGFSGSMCQLDVDECASTPCRNGAKCVDQPDG---YECRCA 535
Query: 196 EGFTGEKCDLRI 231
EGF G C+ +
Sbjct: 536 EGFEGTLCERNV 547
Score = 40.4 bits (93), Expect = 0.006
Identities = 19/67 (28%), Positives = 27/67 (40%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C N G C++ ++ C C Y G C+ G H + C+C E
Sbjct: 934 CFNGGTCVDGVSSFSCLCRPGYTGTHCQYEADPCFSRPCLHGGICNPTHPG--FECTCRE 991
Query: 199 GFTGEKC 219
GFTG +C
Sbjct: 992 GFTGSQC 998
Score = 40.4 bits (93), Expect = 0.006
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
CQ G CI+ G ++ C C + G CE + G C G Y C C
Sbjct: 1056 CQEGGKCIDKGRSHYCVCPEGRTGSHCEHEVDPCTAQPCQHGGTCRGYMGG---YVCECP 1112
Query: 196 EGFTGEKCDLRI----YQPC 243
G+ G+ C+ I QPC
Sbjct: 1113 AGYAGDSCEDNIDECASQPC 1132
Score = 39.7 bits (91), Expect = 0.010
Identities = 33/135 (24%), Positives = 46/135 (34%), Gaps = 14/135 (10%)
Frame = +1
Query: 7 SNIQCQNNGYCINNGLTYECKCLDSYIGKLCE-----------KXXXXXXXXXXXXGKCF 153
S CQN G C+ G C C + G+LC+ + GKC
Sbjct: 1006 SQAPCQNGGRCVQTGA--YCICPPGWSGRLCDIQSLPCTEAAAQMGVRLEQLCQEGGKCI 1063
Query: 154 VQNHGDKLYACSCSEGFTGEKCDLRIYQPCI---CPKNMKCNYSESGALFSCTSENEADS 324
+ + + C C EG TG C+ + PC C C G + C + DS
Sbjct: 1064 DKG---RSHYCVCPEGRTGSHCEHEV-DPCTAQPCQHGGTCRGYMGGYVCECPAGYAGDS 1119
Query: 325 SNPKSDYSNRKVKQN 369
D + QN
Sbjct: 1120 CEDNIDECASQPCQN 1134
Score = 38.5 bits (88), Expect = 0.023
Identities = 27/96 (28%), Positives = 36/96 (37%), Gaps = 2/96 (2%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+ G C++ Y C+C G CE G C G Y C C
Sbjct: 592 CRYGGKCLDLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFGVC---RDGINRYDCVCQP 648
Query: 199 GFTGEKCDLRIYQ--PCICPKNMKCNYSESGALFSC 300
GFTG C++ I + C + C E+G F C
Sbjct: 649 GFTGPLCNVEINECASSPCGEGGSCVDGENG--FHC 682
Score = 37.7 bits (86), Expect = 0.038
Identities = 28/114 (24%), Positives = 41/114 (35%), Gaps = 6/114 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYE--CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQN-HGDKLYACS 189
C N G C + + E C CL ++G+ C+ G C G ++C
Sbjct: 49 CANGGRCTHQQPSLEAACLCLPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCR 108
Query: 190 CSEGFTGEKCDLRIYQPCI---CPKNMKCNYSESGALFSCTSENEADSSNPKSD 342
C GF G C PC+ C C+ G F+C + +SD
Sbjct: 109 CLRGFQGPDCSQP--DPCVSRPCVHGAPCSVGPDGR-FACACPPGYQGQSCQSD 159
Score = 36.6 bits (83), Expect = 0.086
Identities = 21/79 (26%), Positives = 30/79 (37%), Gaps = 4/79 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C +G C N + C C Y G C++ G G ++CSC +
Sbjct: 821 CGPHGTCTNLPGNFRCICHRGYTGPFCDQDIDDCDPNPCLHGGSCQDGVGS--FSCSCLD 878
Query: 199 GFTGEKC----DLRIYQPC 243
GF G +C D + PC
Sbjct: 879 GFAGPRCARDVDECLSSPC 897
Score = 36.6 bits (83), Expect = 0.086
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 2/96 (2%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C + G C + ++ C CLD + G C + G C +H + C+C
Sbjct: 859 CLHGGSCQDGVGSFSCSCLDGFAGPRCARDVDECLSSPCGPGTC--TDHVAS-FTCACPP 915
Query: 199 GFTGEKC--DLRIYQPCICPKNMKCNYSESGALFSC 300
G+ G C DL P C C + + FSC
Sbjct: 916 GYGGFHCEIDLPDCSPSSCFNGGTC--VDGVSSFSC 949
Score = 36.2 bits (82), Expect = 0.11
Identities = 21/76 (27%), Positives = 30/76 (39%), Gaps = 5/76 (6%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKL-----YA 183
CQN G CI+ Y C C +G LCE ++G + +
Sbjct: 1132 CQNGGSCIDLVARYLCSCPPGTLGVLCEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFR 1191
Query: 184 CSCSEGFTGEKCDLRI 231
C+C G+TG C+ I
Sbjct: 1192 CNCPPGYTGLHCEADI 1207
Score = 33.9 bits (76), Expect = 0.55
Identities = 20/73 (27%), Positives = 30/73 (41%), Gaps = 6/73 (8%)
Frame = +1
Query: 19 CQNNGYCINN-----GLTYECKCLDSYIGKLCEKXXXXXXXXXXXXG-KCFVQNHGDKLY 180
CQ+ G C ++ GLT+ C C+ + G CE+ G C G +
Sbjct: 1256 CQHGGQCRHSLGRGGGLTFTCHCVPPFWGLRCERVARSCRELQCPVGIPCQQTARGPR-- 1313
Query: 181 ACSCSEGFTGEKC 219
C+C G +G C
Sbjct: 1314 -CACPPGLSGPSC 1325
Score = 33.1 bits (74), Expect = 0.95
Identities = 19/75 (25%), Positives = 28/75 (37%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C + G C +EC C + + G C+ G VQ C C
Sbjct: 972 CLHGGICNPTHPGFECTCREGFTGSQCQNPVDWCSQAPCQNGGRCVQTGA----YCICPP 1027
Query: 199 GFTGEKCDLRIYQPC 243
G++G CD++ PC
Sbjct: 1028 GWSGRLCDIQSL-PC 1041
>sp|Q9R172|NOTC3_RAT Neurogenic locus notch homolog protein 3 precursor (Notch 3)
[Contains: Notch 3 extracellular truncation; Notch 3
intracellular domain]
Length = 2319
Score = 52.8 bits (125), Expect = 1e-06
Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+N C++ YEC+C + + G LCE+ G+C G ++C+C+
Sbjct: 518 CRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRCV---DGIASFSCACAP 574
Query: 199 GFTGEKCDLRI----YQPC 243
G+TG +C+ ++ QPC
Sbjct: 575 GYTGIRCESQVDECRSQPC 593
Score = 45.8 bits (107), Expect = 1e-04
Identities = 22/71 (30%), Positives = 32/71 (45%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C++ G CIN ++ C C Y G LCE G Q+ D Y C+C
Sbjct: 170 CRHGGTCINTPGSFHCLCPLGYTGLLCENPIVPCAPSPCRNGGTCRQS-SDVTYDCACLP 228
Query: 199 GFTGEKCDLRI 231
GF G+ C++ +
Sbjct: 229 GFEGQNCEVNV 239
Score = 45.1 bits (105), Expect = 2e-04
Identities = 20/67 (29%), Positives = 30/67 (44%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
CQ G C ++G+ + C C + G CE G C ++ D+L CSC
Sbjct: 745 CQAGGTCTSDGIGFHCTCAPGFQGHQCEVLSPCTPSLCEHGGHC--ESDPDQLTVCSCPP 802
Query: 199 GFTGEKC 219
G+ G +C
Sbjct: 803 GWQGPRC 809
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 11/111 (9%)
Frame = +1
Query: 1 ISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKL- 177
+ S ++C +NG C++ + C C Y G CE G C + D L
Sbjct: 1172 LDSGLRCLHNGTCVDLVGGFRCNCPPGYTGLHCE-----ADINECRPGTCHAAHTRDCLQ 1226
Query: 178 -----YACSCSEGFTGEKCDLRIY----QPCICPKNMKCNYSESGAL-FSC 300
+ C C GFTG +C ++ QPC + + G L F+C
Sbjct: 1227 DPGGHFRCICLPGFTGPRCQTALFPCESQPCQHGGQCRPSLGRGGGLTFTC 1277
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
Frame = +1
Query: 16 QCQNNGYCINNGLTYECKCLDSYIGKLCEK---XXXXXXXXXXXXGKCFVQNHGDKLYAC 186
+C N G C++ TY C+C + G+ C + G CF G ++C
Sbjct: 246 RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNLLGG---HSC 302
Query: 187 SCSEGFTGEKCDLRI 231
C G+TGE C I
Sbjct: 303 VCVNGWTGESCSQNI 317
Score = 41.6 bits (96), Expect = 0.003
Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
C N G C++ ++ C C Y G C+ K G C + G + C+C
Sbjct: 935 CFNGGTCVDGVNSFSCLCRPGYTGTHCQYKVDPCFSRPCLHGGICNPTHSG---FECTCR 991
Query: 196 EGFTGEKC 219
EGFTG +C
Sbjct: 992 EGFTGNQC 999
Score = 40.4 bits (93), Expect = 0.006
Identities = 29/110 (26%), Positives = 42/110 (38%), Gaps = 2/110 (1%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C++ G C+N ++ C+C Y G CE + G + C C
Sbjct: 404 CEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ--FTCICMA 461
Query: 199 GFTGEKCDLRI--YQPCICPKNMKCNYSESGALFSCTSENEADSSNPKSD 342
GFTG C++ I Q C C +G FSCT + S + D
Sbjct: 462 GFTGTFCEVDIDECQSSPCVNGGVCKDRVNG--FSCTCPSGFSGSTCQLD 509
Score = 39.7 bits (91), Expect = 0.010
Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 3/94 (3%)
Frame = +1
Query: 31 GYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTG 210
G C ++ ++ C C Y G CE G V G ++C C G+TG
Sbjct: 901 GTCTDHVASFTCTCPPGYGGFHCETDLLDCSPSSCFNGGTCVD--GVNSFSCLCRPGYTG 958
Query: 211 EKCDLRIYQPCI---CPKNMKCNYSESGALFSCT 303
C ++ PC C CN + SG F CT
Sbjct: 959 THCQYKV-DPCFSRPCLHGGICNPTHSG--FECT 989
Score = 39.3 bits (90), Expect = 0.013
Identities = 29/114 (25%), Positives = 41/114 (35%), Gaps = 6/114 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYE--CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQN-HGDKLYACS 189
C N G C + + E C CL ++G+ C+ G C G ++C
Sbjct: 50 CANGGRCTHQQPSREAACLCLPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGVARFSCR 109
Query: 190 CSEGFTGEKCDLRIYQPCI---CPKNMKCNYSESGALFSCTSENEADSSNPKSD 342
C GF G C L PC C C+ G ++C N +SD
Sbjct: 110 CLRGFRGPDCSLP--DPCFSSPCAHGAPCSVGSDGR-YACACPPGYQGRNCRSD 160
Score = 38.5 bits (88), Expect = 0.023
Identities = 27/96 (28%), Positives = 36/96 (37%), Gaps = 2/96 (2%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+ G C++ Y C+C G CE G C G Y C C
Sbjct: 593 CRYGGKCLDLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFGVC---RDGINRYDCVCQP 649
Query: 199 GFTGEKCDLRIYQ--PCICPKNMKCNYSESGALFSC 300
GFTG C++ I + C + C E+G F C
Sbjct: 650 GFTGPLCNVEINECASSPCGEGGSCVDGENG--FHC 683
Score = 38.1 bits (87), Expect = 0.029
Identities = 24/95 (25%), Positives = 36/95 (37%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C +G C N ++ C C Y G C++ G G ++CSC
Sbjct: 822 CGPHGTCTNLPGSFRCICHGGYTGPFCDQDIDDCDPNPCLNGGSCQDGVGS--FSCSCLS 879
Query: 199 GFTGEKCDLRIYQPCICPKNMKCNYSESGALFSCT 303
GF G +C R C+ ++ A F+CT
Sbjct: 880 GFAGPRC-ARDVDECLSSPCGPGTCTDHVASFTCT 913
Score = 37.7 bits (86), Expect = 0.038
Identities = 32/135 (23%), Positives = 44/135 (32%), Gaps = 14/135 (10%)
Frame = +1
Query: 7 SNIQCQNNGYCINNGLTYECKCLDSYIGKLCE-----------KXXXXXXXXXXXXGKCF 153
S CQN G C+ G C C + G LC+ G+C
Sbjct: 1007 SQAPCQNGGRCVQTGA--YCICPPEWSGPLCDIPSLPCTEAAAHMGVRLEQLCQAGGQCI 1064
Query: 154 VQNHGDKLYACSCSEGFTGEKCDLRIYQPCI---CPKNMKCNYSESGALFSCTSENEADS 324
++H + C C EG G C+ + PC C C G + C + DS
Sbjct: 1065 DKDHS---HYCVCPEGRMGSHCEQEV-DPCTAQPCQHGGTCRGYMGGYVCECPTGYSGDS 1120
Query: 325 SNPKSDYSNRKVKQN 369
D + QN
Sbjct: 1121 CEDDVDECASQPCQN 1135
Score = 37.4 bits (85), Expect = 0.050
Identities = 28/124 (22%), Positives = 44/124 (35%), Gaps = 10/124 (8%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
C+N C++ + C C+ + G CE G C + +G ++C+C
Sbjct: 442 CRNQATCLDRIGQFTCICMAGFTGTFCEVDIDECQSSPCVNGGVCKDRVNG---FSCTCP 498
Query: 196 EGFTGEKCDLRIYQ--PCICPKNMKCNYSESGALFSCTS-------ENEADSSNPKSDYS 348
GF+G C L + + C KC G C E D +P +
Sbjct: 499 SGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHH 558
Query: 349 NRKV 360
R V
Sbjct: 559 GRCV 562
Score = 35.8 bits (81), Expect = 0.15
Identities = 21/76 (27%), Positives = 30/76 (39%), Gaps = 5/76 (6%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKL-----YA 183
CQN G CI+ Y C C +G LCE ++G + +
Sbjct: 1133 CQNGGSCIDLVAHYLCSCPPGTLGVLCEINEDDCGPGPSLDSGLRCLHNGTCVDLVGGFR 1192
Query: 184 CSCSEGFTGEKCDLRI 231
C+C G+TG C+ I
Sbjct: 1193 CNCPPGYTGLHCEADI 1208
Score = 35.4 bits (80), Expect = 0.19
Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 2/85 (2%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C N G C + ++ C CL + G C + G C +H + C+C
Sbjct: 860 CLNGGSCQDGVGSFSCSCLSGFAGPRCARDVDECLSSPCGPGTC--TDHVAS-FTCTCPP 916
Query: 199 GFTGEKC--DLRIYQPCICPKNMKC 267
G+ G C DL P C C
Sbjct: 917 GYGGFHCETDLLDCSPSSCFNGGTC 941
Score = 33.5 bits (75), Expect = 0.72
Identities = 20/73 (27%), Positives = 28/73 (38%), Gaps = 6/73 (8%)
Frame = +1
Query: 19 CQNNGYCI-----NNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXG-KCFVQNHGDKLY 180
CQ+ G C GLT+ C C+ + G CE+ G C G +
Sbjct: 1257 CQHGGQCRPSLGRGGGLTFTCHCVQPFWGLRCERVARSCRELQCPVGIPCQQTARGPR-- 1314
Query: 181 ACSCSEGFTGEKC 219
C+C G +G C
Sbjct: 1315 -CACPPGLSGPSC 1326
>sp|P31695|NOTC4_MOUSE Neurogenic locus notch homolog protein 4 precursor (Notch 4)
[Contains: Transforming protein Int-3; Notch 4
extracellular truncation; Notch 4 intracellular domain]
Length = 1964
Score = 52.8 bits (125), Expect = 1e-06
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 3/97 (3%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGK-CFVQNHGDKLYACSCS 195
CQN G CI+ G +Y C+C + GKLC+ G C Q G Y C C+
Sbjct: 897 CQNGGLCIDTGSSYFCRCPPGFQGKLCQDNMNPCEPNPCHHGSTCVPQPSG---YVCQCA 953
Query: 196 EGFTGEKCD--LRIYQPCICPKNMKCNYSESGALFSC 300
G+ G+ C L Q C + C G +C
Sbjct: 954 PGYEGQNCSKVLEACQSQPCHNHGTCTSRPGGFHCAC 990
Score = 50.1 bits (118), Expect = 7e-06
Identities = 27/98 (27%), Positives = 40/98 (40%)
Frame = +1
Query: 7 SNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYAC 186
S+ C N G C + + C+CL + G CEK G + G + C
Sbjct: 553 SSTPCANGGRCRDQPGAFYCECLPGFEGPHCEKEVDECLSDPCPVGASCLDLPG--AFFC 610
Query: 187 SCSEGFTGEKCDLRIYQPCICPKNMKCNYSESGALFSC 300
C GFTG+ C++ + P +C +C E A C
Sbjct: 611 LCRPGFTGQLCEVPLCTPNMCQPGQQCQGQEHRAPCLC 648
Score = 45.4 bits (106), Expect = 2e-04
Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 4/98 (4%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C N G C+N T+ C C + G CE+ K Q+ + C CS
Sbjct: 773 CLNGGTCVNKPGTFFCLCATGFQGLHCEEKTNPSCADSPCRNKATCQD-TPRGARCLCSP 831
Query: 199 GFTGEKC----DLRIYQPCICPKNMKCNYSESGALFSC 300
G+TG C DL +P CP +C +SG F C
Sbjct: 832 GYTGSSCQTLIDLCARKP--CPHTARC--LQSGPSFQC 865
Score = 43.5 bits (101), Expect = 7e-04
Identities = 30/116 (25%), Positives = 39/116 (33%), Gaps = 3/116 (2%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C N G C Y C CL S+ G+ C+ G V G + C C+
Sbjct: 735 CLNGGSCSIRPEGYSCTCLPSHTGRHCQTAVDHCVSASCLNGGTCVNKPG--TFFCLCAT 792
Query: 199 GFTGEKCDLRIYQPCI---CPKNMKCNYSESGALFSCTSENEADSSNPKSDYSNRK 357
GF G C+ + C C C + GA C+ S D RK
Sbjct: 793 GFQGLHCEEKTNPSCADSPCRNKATCQDTPRGARCLCSPGYTGSSCQTLIDLCARK 848
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 3/79 (3%)
Frame = +1
Query: 16 QCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
+C+N G C N ++ C C+ + G CE+ G + G ++C C
Sbjct: 322 RCRNGGTCQNTAGSFHCVCVSGWGGAGCEENLDDCAAATCAPGSTCIDRVGS--FSCLCP 379
Query: 196 EGFTGEKC---DLRIYQPC 243
G TG C D+ + QPC
Sbjct: 380 PGRTGLLCHLEDMCLSQPC 398
Score = 39.7 bits (91), Expect = 0.010
Identities = 28/113 (24%), Positives = 42/113 (37%), Gaps = 11/113 (9%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE----KXXXXXXXXXXXXGKCFVQNHG-----D 171
C + C+ +G +++C CL + G LC+ G C QN G
Sbjct: 850 CPHTARCLQSGPSFQCLCLQGWTGALCDFPLSCQMAAMSQGIEISGLC--QNGGLCIDTG 907
Query: 172 KLYACSCSEGFTGEKC--DLRIYQPCICPKNMKCNYSESGALFSCTSENEADS 324
Y C C GF G+ C ++ +P C C SG + C E +
Sbjct: 908 SSYFCRCPPGFQGKLCQDNMNPCEPNPCHHGSTCVPQPSGYVCQCAPGYEGQN 960
Score = 38.9 bits (89), Expect = 0.017
Identities = 20/80 (25%), Positives = 31/80 (38%), Gaps = 4/80 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C++ G CIN ++ C CL Y G CE G + + C C
Sbjct: 443 CEHGGSCINTPGSFNCLCLPGYTGSRCEADHNECLSQPCHPGSTCLDLLA--TFHCLCPP 500
Query: 199 GFTGEKCDLRIYQ----PCI 246
G G C++ + + PC+
Sbjct: 501 GLEGRLCEVEVNECTSNPCL 520
Score = 37.0 bits (84), Expect = 0.066
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 5/67 (7%)
Frame = +1
Query: 58 YECKCLDSYIGKLCEKXXXXXXXXXXXX--GKCFVQNHGDKLYACSCSEGFTGEKCDLRI 231
+ C C + G C+ G C+VQ G CSC G+TGE+C LR
Sbjct: 98 FSCTCPSGFTGDRCQTHLEELCPPSFCSNGGHCYVQASGRP--QCSCEPGWTGEQCQLRD 155
Query: 232 Y---QPC 243
+ PC
Sbjct: 156 FCSANPC 162
Score = 36.6 bits (83), Expect = 0.086
Identities = 20/79 (25%), Positives = 29/79 (36%), Gaps = 4/79 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C N+G C + + C C ++G CE + + C C
Sbjct: 973 CHNHGTCTSRPGGFHCACPPGFVGLRCEGDVDECLDRPCHPSGTAACHSLANAFYCQCLP 1032
Query: 199 GFTGEKC----DLRIYQPC 243
G TG++C DL QPC
Sbjct: 1033 GHTGQRCEVEMDLCQSQPC 1051
Score = 36.2 bits (82), Expect = 0.11
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 1/72 (1%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLC-EKXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
C + G C Y C C Y+G C E+ G C ++ G Y+C+C
Sbjct: 697 CAHGGTCHPQPSGYNCTCPAGYMGLTCSEEVTACHSGPCLNGGSCSIRPEG---YSCTCL 753
Query: 196 EGFTGEKCDLRI 231
TG C +
Sbjct: 754 PSHTGRHCQTAV 765
Score = 34.3 bits (77), Expect = 0.42
Identities = 23/87 (26%), Positives = 32/87 (36%), Gaps = 4/87 (4%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEK-XXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
C N C + ++C CL + G CEK G+C Q + C C
Sbjct: 519 CLNQAACHDLLNGFQCLCLPGFTGARCEKDMDECSSTPCANGGRCRDQ---PGAFYCECL 575
Query: 196 EGFTGEKCDLRIYQPCI---CPKNMKC 267
GF G C+ + C+ CP C
Sbjct: 576 PGFEGPHCEKEV-DECLSDPCPVGASC 601
Score = 32.3 bits (72), Expect = 1.6
Identities = 24/108 (22%), Positives = 40/108 (37%), Gaps = 19/108 (17%)
Frame = +1
Query: 19 CQNNGYCIN----NGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFV--------Q 159
C N G C+ G+ C+C ++G+ C+ G C +
Sbjct: 32 CANGGTCLRLSQGQGI---CQCAPGFLGETCQFPDPCRDTQLCKNGGSCQALLPTPPSSR 88
Query: 160 NHGDKL---YACSCSEGFTGEKCDLRIYQ---PCICPKNMKCNYSESG 285
+ L ++C+C GFTG++C + + P C C SG
Sbjct: 89 SPTSPLTPHFSCTCPSGFTGDRCQTHLEELCPPSFCSNGGHCYVQASG 136
Score = 32.0 bits (71), Expect = 2.1
Identities = 17/70 (24%), Positives = 26/70 (37%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C N G C+ +C+C + G CE+ + ++ Y C C
Sbjct: 162 CANGGVCLATYPQIQCRCPPGFEGHTCERDINECFLEPGPCPQGTSCHNTLGSYQCLCPV 221
Query: 199 GFTGEKCDLR 228
G G +C LR
Sbjct: 222 GQEGPQCKLR 231
Score = 31.2 bits (69), Expect = 3.6
Identities = 15/62 (24%), Positives = 24/62 (38%), Gaps = 1/62 (1%)
Frame = +1
Query: 37 CINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGE 213
C + + C+CL + G+ CE + G C + + C C +GF G
Sbjct: 1019 CHSLANAFYCQCLPGHTGQRCEVEMDLCQSQPCSNGGSCEITTGPPPGFTCHCPKGFEGP 1078
Query: 214 KC 219
C
Sbjct: 1079 TC 1080
Score = 30.0 bits (66), Expect = 8.0
Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 4/73 (5%)
Frame = +1
Query: 16 QCQNNGYCINNGLTYECKCLDSYIGKLC----EKXXXXXXXXXXXXGKCFVQNHGDKLYA 183
QCQN C++ TY C C ++ G C ++ G C QN +
Sbjct: 281 QCQNGATCLDGLDTYTCLCPKTWKGWDCSEDIDECEARGPPRCRNGGTC--QNTAGSFH- 337
Query: 184 CSCSEGFTGEKCD 222
C C G+ G C+
Sbjct: 338 CVCVSGWGGAGCE 350
>sp|P24014|SLIT_DROME Slit protein precursor [Contains: Slit protein N-product; Slit
protein C-product]
Length = 1504
Score = 52.4 bits (124), Expect = 2e-06
Identities = 26/80 (32%), Positives = 33/80 (41%), Gaps = 9/80 (11%)
Frame = +1
Query: 10 NIQCQNNGYCINNGLTYECKCLDSYIGKLCE---------KXXXXXXXXXXXXGKCFVQN 162
N CQN G C++ Y+C+C D Y GK CE G CF N
Sbjct: 1094 NHMCQNGGTCVDGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKHGVCFQPN 1153
Query: 163 HGDKLYACSCSEGFTGEKCD 222
Y C C G+TG+ C+
Sbjct: 1154 AQGSDYLCRCHPGYTGKWCE 1173
Score = 42.4 bits (98), Expect = 0.002
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Frame = +1
Query: 13 IQCQNNGYCINNGLTYECKCLDSYIGKLCE---KXXXXXXXXXXXXGKCFVQNHGDKLYA 183
I+CQNN CI+ +Y+C+C + G+ C+ + KC +H Y+
Sbjct: 1017 IKCQNNATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPCANGAKC--MDHFTH-YS 1073
Query: 184 CSCSEGFTGEKC 219
C C GF G C
Sbjct: 1074 CDCQAGFHGTNC 1085
Score = 41.6 bits (96), Expect = 0.003
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 13/88 (14%)
Frame = +1
Query: 19 CQNNGYC--INNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNH-----GDKL 177
C+NN C + G + C+C Y G CE G+ QN+ G +
Sbjct: 979 CRNNATCTVLEEG-RFSCQCAPGYTGARCETNIDDCL------GEIKCQNNATCIDGVES 1031
Query: 178 YACSCSEGFTGEKCDLRI------YQPC 243
Y C C GF+GE CD +I + PC
Sbjct: 1032 YKCECQPGFSGEFCDTKIQFCSPEFNPC 1059
Score = 35.4 bits (80), Expect = 0.19
Identities = 20/87 (22%), Positives = 30/87 (34%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C N C+++ Y C C + G C G V D Y C C +
Sbjct: 1059 CANGAKCMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGIND--YQCRCPD 1116
Query: 199 GFTGEKCDLRIYQPCICPKNMKCNYSE 279
+TG+ C+ + P+ C E
Sbjct: 1117 DYTGKYCEGHNMISMMYPQTSPCQNHE 1143
>sp|Q9UM47|NOTC3_HUMAN Neurogenic locus notch homolog protein 3 precursor (Notch 3)
[Contains: Notch 3 extracellular truncation; Notch 3
intracellular domain]
Length = 2321
Score = 52.4 bits (124), Expect = 2e-06
Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+N C++ YEC+C + + G LC++ G+C G ++C+C+
Sbjct: 516 CRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCV---DGIASFSCACAP 572
Query: 199 GFTGEKCDLRI----YQPC 243
G+TG +C+ ++ QPC
Sbjct: 573 GYTGTRCESQVDECRSQPC 591
Score = 49.7 bits (117), Expect = 1e-05
Identities = 22/71 (30%), Positives = 34/71 (47%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C++ G C+N ++ C+C Y G LCE G Q+ GD Y C+C
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQS-GDLTYDCACLP 226
Query: 199 GFTGEKCDLRI 231
GF G+ C++ +
Sbjct: 227 GFEGQNCEVNV 237
Score = 43.1 bits (100), Expect = 0.001
Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 3/98 (3%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+ G C ++G+ + C C G+ CE G+C ++ +L CSC +
Sbjct: 743 CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRC--ESAPGQLPVCSCPQ 800
Query: 199 GFTGEKCDLRIYQ---PCICPKNMKCNYSESGALFSCT 303
G+ G +C + + P C + C + FSCT
Sbjct: 801 GWQGPRCQQDVDECAGPAPCGPHGIC--TNLAGSFSCT 836
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
Frame = +1
Query: 16 QCQNNGYCINNGLTYECKCLDSYIGKLCEK---XXXXXXXXXXXXGKCFVQNHGDKLYAC 186
+C N G C++ TY C+C + G+ C + G CF G ++C
Sbjct: 244 RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGG---HSC 300
Query: 187 SCSEGFTGEKCDLRI 231
C G+TGE C I
Sbjct: 301 VCVNGWTGESCSQNI 315
Score = 40.8 bits (94), Expect = 0.005
Identities = 29/110 (26%), Positives = 42/110 (38%), Gaps = 2/110 (1%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C++ G C+N ++ C+C Y G CE + G + C C
Sbjct: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ--FTCICMA 459
Query: 199 GFTGEKCDLRI--YQPCICPKNMKCNYSESGALFSCTSENEADSSNPKSD 342
GFTG C++ I Q C C +G FSCT + S + D
Sbjct: 460 GFTGTYCEVDIDECQSSPCVNGGVCKDRVNG--FSCTCPSGFSGSTCQLD 507
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/96 (28%), Positives = 37/96 (38%), Gaps = 2/96 (2%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C++ G C++ Y C+C G CE G C G Y C C
Sbjct: 591 CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVC---RDGINRYDCVCQP 647
Query: 199 GFTGEKCDLRIYQ--PCICPKNMKCNYSESGALFSC 300
GFTG C++ I + C + C E+G F C
Sbjct: 648 GFTGPLCNVEINECASSPCGEGGSCVDGENG--FRC 681
Score = 39.7 bits (91), Expect = 0.010
Identities = 22/80 (27%), Positives = 33/80 (41%), Gaps = 5/80 (6%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
C N G C++ ++ C C Y G C+ + G C + G + C+C
Sbjct: 933 CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPG---FRCTCL 989
Query: 196 EGFTGEKCDLRI----YQPC 243
E FTG +C + QPC
Sbjct: 990 ESFTGPQCQTLVDWCSRQPC 1009
Score = 38.9 bits (89), Expect = 0.017
Identities = 29/112 (25%), Positives = 42/112 (37%), Gaps = 12/112 (10%)
Frame = +1
Query: 1 ISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKL- 177
+ S +C +NG C++ + C C Y G CE G C + D L
Sbjct: 1170 LDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE-----ADINECRSGACHAAHTRDCLQ 1224
Query: 178 -----YACSCSEGFTGEKCDLRIYQPC---ICPKNMKCNYSE---SGALFSC 300
+ C C GF+G +C + PC C +C S G F+C
Sbjct: 1225 DPGGGFRCLCHAGFSGPRCQ-TVLSPCESQPCQHGGQCRPSPGPGGGLTFTC 1275
Score = 38.5 bits (88), Expect = 0.023
Identities = 24/95 (25%), Positives = 36/95 (37%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C +G C N ++ C C Y G C++ G G ++CSC
Sbjct: 820 CGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGS--FSCSCLP 877
Query: 199 GFTGEKCDLRIYQPCICPKNMKCNYSESGALFSCT 303
GF G +C R C+ ++ A F+CT
Sbjct: 878 GFAGPRC-ARDVDECLSNPCGPGTCTDHVASFTCT 911
Score = 36.2 bits (82), Expect = 0.11
Identities = 21/86 (24%), Positives = 35/86 (40%), Gaps = 3/86 (3%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
C+N C++ + C C+ + G CE G C + +G ++C+C
Sbjct: 440 CRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNG---FSCTCP 496
Query: 196 EGFTGEKCDLRIYQ--PCICPKNMKC 267
GF+G C L + + C KC
Sbjct: 497 SGFSGSTCQLDVDECASTPCRNGAKC 522
Score = 35.8 bits (81), Expect = 0.15
Identities = 28/119 (23%), Positives = 41/119 (34%), Gaps = 5/119 (4%)
Frame = +1
Query: 19 CQNNGYCIN-NGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQN-HGDKLYACSC 192
C N G C C C ++G+ C+ G C G ++C C
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108
Query: 193 SEGFTGEKCDLRIYQPCI---CPKNMKCNYSESGALFSCTSENEADSSNPKSDYSNRKV 360
GF G C L PC+ C +C+ G F C+ + +SD +V
Sbjct: 109 PRGFRGPDCSLP--DPCLSSPCAHGARCSVGPDGR-FLCSCPPGYQGRSCRSDVDECRV 164
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/75 (28%), Positives = 29/75 (38%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C + G C + C CL+S+ G C+ G VQ C C
Sbjct: 971 CLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGA----YCLCPP 1026
Query: 199 GFTGEKCDLRIYQPC 243
G++G CD+R PC
Sbjct: 1027 GWSGRLCDIRSL-PC 1040
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/79 (26%), Positives = 29/79 (36%), Gaps = 4/79 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
CQ G C++ ++ C C + G CE+ G G Y C C
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGG--YMCECLP 1112
Query: 199 GFTGEKC----DLRIYQPC 243
G+ G+ C D QPC
Sbjct: 1113 GYNGDNCEDDVDECASQPC 1131
Score = 35.0 bits (79), Expect = 0.25
Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 2/85 (2%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C N G C + ++ C CL + G C + G C +H + C+C
Sbjct: 858 CLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTC--TDHVAS-FTCTCPP 914
Query: 199 GFTGEKC--DLRIYQPCICPKNMKC 267
G+ G C DL P C C
Sbjct: 915 GYGGFHCEQDLPDCSPSSCFNGGTC 939
Score = 34.7 bits (78), Expect = 0.33
Identities = 20/76 (26%), Positives = 31/76 (40%), Gaps = 5/76 (6%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKL-----YA 183
CQ+ G CI+ Y C C +G LCE ++G + +
Sbjct: 1131 CQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFR 1190
Query: 184 CSCSEGFTGEKCDLRI 231
C+C G+TG +C+ I
Sbjct: 1191 CTCPPGYTGLRCEADI 1206
Score = 33.5 bits (75), Expect = 0.72
Identities = 20/69 (28%), Positives = 25/69 (36%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
CQ+ G C Y C+CL Y G CE G + Y CSC
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVA--RYLCSCPP 1150
Query: 199 GFTGEKCDL 225
G G C++
Sbjct: 1151 GTLGVLCEI 1159
Score = 33.1 bits (74), Expect = 0.95
Identities = 20/73 (27%), Positives = 27/73 (36%), Gaps = 6/73 (8%)
Frame = +1
Query: 19 CQNNGYCI-----NNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXG-KCFVQNHGDKLY 180
CQ+ G C GLT+ C C + G CE+ G C G +
Sbjct: 1255 CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPR-- 1312
Query: 181 ACSCSEGFTGEKC 219
C+C G +G C
Sbjct: 1313 -CACPPGLSGPSC 1324
Score = 31.2 bits (69), Expect = 3.6
Identities = 22/99 (22%), Positives = 33/99 (33%), Gaps = 4/99 (4%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C G C++ + C C + LC G C+ G + C C
Sbjct: 666 CGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGG---FRCVCEP 722
Query: 199 GFTGEKCDLRIYQPCI----CPKNMKCNYSESGALFSCT 303
G++G +C + + C C S G F CT
Sbjct: 723 GWSGPRCSQSLARDACESQPCRAGGTC--SSDGMGFHCT 759
>sp|P21783|NOTCH_XENLA Neurogenic locus notch protein homolog precursor (XOTCH protein)
Length = 2524
Score = 51.6 bits (122), Expect = 3e-06
Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 3/111 (2%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+N C++ +Y C+C + + G+ CE+ G C G + C C
Sbjct: 536 CKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDPCHYGTC---KDGIATFTCLCRP 592
Query: 199 GFTGEKCDLRIYQPCI---CPKNMKCNYSESGALFSCTSENEADSSNPKSD 342
G+TG CD I + C+ C +C E+G + +C + K D
Sbjct: 593 GYTGRLCDNDINE-CLSKPCLNGGQCTDRENGYICTCPKGTTGVNCETKID 642
Score = 51.2 bits (121), Expect = 3e-06
Identities = 31/124 (25%), Positives = 57/124 (45%)
Frame = +1
Query: 7 SNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYAC 186
S+ C N+G CI++ Y+C C+ Y G +CE G ++ + ++C
Sbjct: 795 SSNPCLNHGTCIDDVAGYKCNCMLPYTGAICEAVLAPCAGSPCKNGGRCKESEDFETFSC 854
Query: 187 SCSEGFTGEKCDLRIYQPCICPKNMKCNYSESGALFSCTSENEADSSNPKSDYSNRKVKQ 366
C G+ G+ C++ + + C+ N C +GA +C + N + N K Y+ R +
Sbjct: 855 ECPPGWQGQTCEIDMNE-CV---NRPC---RNGA--TCQNTNGSYKCNCKPGYTGRNCEM 905
Query: 367 NWKD 378
+ D
Sbjct: 906 DIDD 909
Score = 48.9 bits (115), Expect = 2e-05
Identities = 25/80 (31%), Positives = 36/80 (45%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+N G CIN +Y C C + + G+ C++ G Q D Y C+C
Sbjct: 188 CKNGGQCINEFGSYRCTCQNRFTGRNCDEPYVPCNPSPCLNGGTCRQT-DDTSYDCTCLP 246
Query: 199 GFTGEKCDLRIYQPCICPKN 258
GF+G+ C+ I CP N
Sbjct: 247 GFSGQNCEENIDD---CPSN 263
Score = 48.1 bits (113), Expect = 3e-05
Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 1/101 (0%)
Frame = +1
Query: 10 NIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXG-KCFVQNHGDKLYAC 186
N C+N C N +Y+C C Y G+ CE G C + G ++ C
Sbjct: 874 NRPCRNGATCQNTNGSYKCNCKPGYTGRNCEMDIDDCQPNPCHNGGSC---SDGINMFFC 930
Query: 187 SCSEGFTGEKCDLRIYQPCICPKNMKCNYSESGALFSCTSE 309
+C GF G KC+ I + P N ++ ++CT +
Sbjct: 931 NCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQ 971
Score = 47.4 bits (111), Expect = 5e-05
Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 4/98 (4%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXG-KCFVQNHGDKLYACSCS 195
C +NG CI+ + C C + G LC+ G KC G Y C C+
Sbjct: 498 CLHNGKCIDKINEFRCDCPTGFSGNLCQHDFDECTSTPCKNGAKCL---DGPNSYTCQCT 554
Query: 196 EGFTGEKCDLRIYQPCICPKNMKCNY---SESGALFSC 300
EGFTG C+ I + CI C+Y + A F+C
Sbjct: 555 EGFTGRHCEQDINE-CIPD---PCHYGTCKDGIATFTC 588
Score = 45.4 bits (106), Expect = 2e-04
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 4/79 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+N+G C++ G T+ C+C Y G CE+ G G Y+C C
Sbjct: 1115 CRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGG--YSCECVA 1172
Query: 199 GFTGEKCDLRIYQ----PC 243
G+ G C I + PC
Sbjct: 1173 GYHGVNCSEEINECLSHPC 1191
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/118 (27%), Positives = 47/118 (39%), Gaps = 6/118 (5%)
Frame = +1
Query: 10 NIQCQNNGYC--INNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYA 183
N C+N G C +N+ Y+C+C + G C++ GKC + Y
Sbjct: 108 NNPCRNGGTCELLNSVTEYKCRCPPGWTGDSCQQADPCASNPCANGGKCL---PFEIQYI 164
Query: 184 CSCSEGFTGEKCDLRIYQ----PCICPKNMKCNYSESGALFSCTSENEADSSNPKSDY 345
C C GF G C I + PC KN +E G+ + CT +N N Y
Sbjct: 165 CKCPPGFHGATCKQDINECSQNPC---KNGGQCINEFGS-YRCTCQNRFTGRNCDEPY 218
Score = 44.7 bits (104), Expect = 3e-04
Identities = 23/75 (30%), Positives = 30/75 (40%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C N G C+ + Y CKC + G C++ G + G Y C+C
Sbjct: 150 CANGGKCLPFEIQYICKCPPGFHGATCKQDINECSQNPCKNGGQCINEFGS--YRCTCQN 207
Query: 199 GFTGEKCDLRIYQPC 243
FTG CD Y PC
Sbjct: 208 RFTGRNCD-EPYVPC 221
Score = 43.9 bits (102), Expect = 5e-04
Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 4/79 (5%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C N G C + Y C C G CE GKC + G Y C+C
Sbjct: 611 CLNGGQCTDRENGYICTCPKGTTGVNCETKIDDCASNLCDNGKCIDKIDG---YECTCEP 667
Query: 199 GFTGEKCDLRIYQ----PC 243
G+TG+ C++ I + PC
Sbjct: 668 GYTGKLCNININECDSNPC 686
Score = 42.7 bits (99), Expect = 0.001
Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 3/99 (3%)
Frame = +1
Query: 16 QCQNNGYCINNGLTYECKCLDSYIGKLCE---KXXXXXXXXXXXXGKCFVQNHGDKLYAC 186
+C NNG CI+ Y C C ++G+ CE C +Q D Y C
Sbjct: 1236 KCFNNGKCIDRVGGYNCICPPGFVGERCEGDVNECLSNPCDSRGTQNC-IQLVND--YRC 1292
Query: 187 SCSEGFTGEKCDLRIYQPCICPKNMKCNYSESGALFSCT 303
C +GFTG +C+ + C K M C + A+ S T
Sbjct: 1293 ECRQGFTGRRCE-SVVDGC---KGMPCRNGGTCAVASNT 1327
Score = 42.4 bits (98), Expect = 0.002
Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 2/85 (2%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C N G CI+ T+ C+C + G C+ G ++G Y C+C +
Sbjct: 991 CFNGGTCIDGINTFTCQCPPGFTGSYCQHDINECDSKPCLNGGTCQDSYG--TYKCTCPQ 1048
Query: 199 GFTGEKCD--LRIYQPCICPKNMKC 267
G+TG C +R C KC
Sbjct: 1049 GYTGLNCQNLVRWCDSSPCKNGGKC 1073
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/101 (27%), Positives = 34/101 (33%), Gaps = 7/101 (6%)
Frame = +1
Query: 19 CQNNGYCI---NNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYAC 186
C+N G C N + CKC + G CE G C K C
Sbjct: 1315 CRNGGTCAVASNTERGFICKCPPGFDGATCEYDSRTCSNLRCQNGGTCISVLTSSK---C 1371
Query: 187 SCSEGFTGEKCDLRIYQPCI---CPKNMKCNYSESGALFSC 300
CSEG+TG C + PC C C + F C
Sbjct: 1372 VCSEGYTGATCQYPVISPCASHPCYNGGTCQFFAEEPFFQC 1412
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/114 (28%), Positives = 44/114 (38%), Gaps = 11/114 (9%)
Frame = +1
Query: 25 NNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEG 201
+NG CI+ YEC C Y GKLC G C Q +G + C C +G
Sbjct: 650 DNGKCIDKIDGYECTCEPGYTGKLCNININECDSNPCRNGGTCKDQING---FTCVCPDG 706
Query: 202 FTGEKCDLRIYQ----PCI---CPKNM---KCNYSESGALFSCTSENEADSSNP 333
+ C + + PCI C + KC+ + +C N SNP
Sbjct: 707 YHDHMCLSEVNECNSNPCIHGACHDGVNGYKCDCEAGWSGSNCDINNNECESNP 760
Score = 40.8 bits (94), Expect = 0.005
Identities = 34/127 (26%), Positives = 50/127 (39%), Gaps = 16/127 (12%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEK---XXXXXXXXXXXXGKCFVQNHGDKLYACS 189
C+N G C++ TY C+C + G+ C + G C G Y C
Sbjct: 265 CRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGG---YNCV 321
Query: 190 CSEGFTGEKCDLRI--------YQPCICPKNM-----KCNYSESGALFSCTSENEADSSN 330
C G+TGE C I + C + +C + +G L C +N A SN
Sbjct: 322 CVNGWTGEDCSENIDDCANAACHSGATCHDRVASFYCECPHGRTGLL--CHLDN-ACISN 378
Query: 331 PKSDYSN 351
P ++ SN
Sbjct: 379 PCNEGSN 385
Score = 40.0 bits (92), Expect = 0.008
Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE---KXXXXXXXXXXXXGKCFVQNHGDKL---- 177
CQN G CI+ TY+C C G CE KCF N+G +
Sbjct: 1191 CQNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSFTLEPKCF--NNGKCIDRVG 1248
Query: 178 -YACSCSEGFTGEKCD 222
Y C C GF GE+C+
Sbjct: 1249 GYNCICPPGFVGERCE 1264
Score = 39.3 bits (90), Expect = 0.013
Identities = 19/69 (27%), Positives = 27/69 (39%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C+N G C + + C C D Y +C G C + G Y C C
Sbjct: 686 CRNGGTCKDQINGFTCVCPDGYHDHMCLSEVNECNSNPCIHGAC---HDGVNGYKCDCEA 742
Query: 199 GFTGEKCDL 225
G++G CD+
Sbjct: 743 GWSGSNCDI 751
Score = 38.5 bits (88), Expect = 0.023
Identities = 20/78 (25%), Positives = 33/78 (42%), Gaps = 1/78 (1%)
Frame = +1
Query: 7 SNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDK-LYA 183
SN++CQN G CI+ + +C C + Y G C+ Q ++ +
Sbjct: 1352 SNLRCQNGGTCISVLTSSKCVCSEGYTGATCQYPVISPCASHPCYNGGTCQFFAEEPFFQ 1411
Query: 184 CSCSEGFTGEKCDLRIYQ 237
C C + F G C + Y+
Sbjct: 1412 CFCPKNFNGLFCHILDYE 1429
Score = 37.0 bits (84), Expect = 0.066
Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 4/87 (4%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 198
C++ G C N +++C C Y G CE + G+ + C C
Sbjct: 422 CEHGGRCTNTLGSFQCNCPQGYAGPRCEIDVNECLSNPCQNDSTCLDQIGE--FQCICMP 479
Query: 199 GFTGEKCDLRIYQ----PCICPKNMKC 267
G+ G C+ I + PC+ N KC
Sbjct: 480 GYEGLYCETNIDECASNPCL--HNGKC 504
Score = 35.8 bits (81), Expect = 0.15
Identities = 24/106 (22%), Positives = 36/106 (33%), Gaps = 10/106 (9%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFV---QNHG-----DK 174
C+N G C Y C+C + G C+ G V +N G
Sbjct: 1067 CKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIVHLCRNSGMCVDTGN 1126
Query: 175 LYACSCSEGFTGEKCDLRIYQ--PCICPKNMKCNYSESGALFSCTS 306
+ C C G+TG C+ ++ + P C C G C +
Sbjct: 1127 THFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCECVA 1172
Score = 32.7 bits (73), Expect = 1.2
Identities = 25/100 (25%), Positives = 36/100 (36%), Gaps = 6/100 (6%)
Frame = +1
Query: 19 CQNNGYC-INNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKL-YACS 189
C N G C + G T C C + Y G+ C+ G C G+ + + C
Sbjct: 29 CLNGGRCEMTPGGTGVCLCGNLYFGERCQFPNPCTIKNQCMNFGTCEPVLQGNAIDFICH 88
Query: 190 CSEGFTGEKCDLRIYQPCI---CPKNMKCNYSESGALFSC 300
C GFT + C + C+ C C S + C
Sbjct: 89 CPVGFTDKVCLTPVDNACVNNPCRNGGTCELLNSVTEYKC 128
Score = 32.0 bits (71), Expect = 2.1
Identities = 19/70 (27%), Positives = 27/70 (38%), Gaps = 2/70 (2%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKL--YACSC 192
C N G C + + C C + G CE+ G N D + Y C+C
Sbjct: 915 CHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGA----NCTDCVNSYTCTC 970
Query: 193 SEGFTGEKCD 222
GF+G C+
Sbjct: 971 QPGFSGIHCE 980
Score = 31.2 bits (69), Expect = 3.6
Identities = 16/72 (22%), Positives = 25/72 (34%)
Frame = +1
Query: 7 SNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYAC 186
+N C + C + ++ C+C G LC C K C
Sbjct: 339 ANAACHSGATCHDRVASFYCECPHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKA-IC 397
Query: 187 SCSEGFTGEKCD 222
+C G+TG C+
Sbjct: 398 TCPPGYTGPACN 409
Score = 31.2 bits (69), Expect = 3.6
Identities = 21/85 (24%), Positives = 31/85 (36%), Gaps = 8/85 (9%)
Frame = +1
Query: 16 QCQNN----GYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYA 183
+C +N G C + Y+C C + G C+ G G Y
Sbjct: 718 ECNSNPCIHGACHDGVNGYKCDCEAGWSGSNCDINNNECESNPCMNGGTCKDMTG--AYI 775
Query: 184 CSCSEGFTGEKCDLRIYQ----PCI 246
C+C GF+G C I + PC+
Sbjct: 776 CTCKAGFSGPNCQTNINECSSNPCL 800
>sp|O57409|DLLB_BRARE Delta-like protein B precursor (DeltaB protein)
Length = 615
Score = 51.2 bits (121), Expect = 3e-06
Identities = 41/161 (25%), Positives = 61/161 (37%), Gaps = 6/161 (3%)
Frame = +1
Query: 7 SNIQCQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYA 183
S+ C N G C++ G + C+C + G CE G C G Y
Sbjct: 392 SHKPCANGGECVDLGASALCRCRPGFSGSRCETNIDDCARYPCQNAGTC---QDGINDYT 448
Query: 184 CSCSEGFTGEKCDLR----IYQPCICPKNMKCNYSESGALFSCTSENEADSSNPKSDYSN 351
C+C+ GFTG+ C LR + PC+ C SG + C + S
Sbjct: 449 CTCTLGFTGKNCSLRADACLTNPCL--HGGTCFTHFSGPVCQCVPGFMGSTCEFPVQASL 506
Query: 352 RKVKQNWKDVSLSTTIVAAV-GCMTILISIGVSIYVCHRTR 471
K+ S S V+ V G + + + + V + V R R
Sbjct: 507 EKMAPRVGQTSPSAVAVSCVLGVLAVFLGVCVGLVVLRRRR 547
Score = 39.3 bits (90), Expect = 0.013
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Frame = +1
Query: 19 CQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 195
C+N G C + Y C C + GK CE G C + G Y C C
Sbjct: 319 CKNGGSCNDLENDYSCTCPQGFYGKNCEIIAMTCADDPCFNGGTCEEKFTGG--YVCRCP 376
Query: 196 EGFTGEKCDLRI----YQPC 243
FTG C+ R+ ++PC
Sbjct: 377 PTFTGSNCEKRLDRCSHKPC 396
Score = 38.1 bits (87), Expect = 0.029
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Frame = +1
Query: 58 YECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ 237
++C C + + G C + N G Y C+C GF G C+L I +
Sbjct: 254 WQCVCKEGWGGLFCNQDLNYCTNHKPCANGATCTNTGQGSYTCTCRPGFGGTNCELEINE 313
Query: 238 -PC-ICPKNMKCNYSESGALFSCT 303
C C CN E+ +SCT
Sbjct: 314 CDCNPCKNGGSCNDLEND--YSCT 335
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.315 0.130 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,422,806
Number of Sequences: 369166
Number of extensions: 1849747
Number of successful extensions: 7834
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4984
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6805
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7907893860
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)