Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_P18-2
(607 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q12955|ANK3_HUMAN Ankyrin-3 (ANK-3) (Ankyrin G) 126 5e-29
sp|P16157|ANK1_HUMAN Ankyrin-1 (Erythrocyte ankyrin) (Ankyr... 123 4e-28
sp|Q02357|ANK1_MOUSE Ankyrin-1 (Erythrocyte ankyrin) 122 5e-28
sp|O15084|ANR28_HUMAN Ankyrin repeat domain protein 28 112 6e-25
sp|Q01484|ANK2_HUMAN Ankyrin-2 (Brain ankyrin) (Ankyrin B) ... 112 7e-25
sp|P53355|DAPK1_HUMAN Death-associated protein kinase 1 (DA... 111 1e-24
sp|P57078|RIPK4_HUMAN Serine/threonine-protein kinase RIPK4... 110 4e-24
sp|Q80YE7|DAPK1_MOUSE Death-associated protein kinase 1 (DA... 105 1e-22
sp|Q8R516|MIB2_MOUSE Ubiquitin ligase protein MIB2 (Mind bo... 100 3e-21
sp|Q96AX9|MIB2_HUMAN Ubiquitin ligase protein MIB2 (Mind bo... 100 4e-21
>sp|Q12955|ANK3_HUMAN Ankyrin-3 (ANK-3) (Ankyrin G)
Length = 4377
Score = 126 bits (316), Expect = 5e-29
Identities = 51/175 (29%), Positives = 97/175 (55%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L+D A +NGY P+H+A + ++I L++ +A + G +HLA + G
Sbjct: 616 LLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEG 675
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
++D+ +L+ + +++ NK G P+HLA + +++ ++L+++ + A K GY P+H
Sbjct: 676 HVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLH 735
Query: 364 LACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
+ C G+I IV L+ + ++ K GY P+H A + GH I+ +L+ N N
Sbjct: 736 VGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPN 790
Score = 122 bits (305), Expect = 9e-28
Identities = 50/176 (28%), Positives = 98/176 (55%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L+ A ++G P+H+A + ++ +L+D+ A KNGY P+H+A +
Sbjct: 583 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN 642
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
+DIA L++ D + + G +HLA + GH+D++ +L+ + +++ SNK G P+H
Sbjct: 643 QMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLH 702
Query: 364 LACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
LA + +++ ++L++ + K GY P+H+ C G+I I+ L+ + +NA
Sbjct: 703 LAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNA 758
Score = 118 bits (295), Expect = 1e-26
Identities = 51/179 (28%), Positives = 99/179 (55%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGY 186
L+D+ +S + G+ P+H+A + G +E+ +L+ K A K+G P+H+A
Sbjct: 551 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDN 610
Query: 187 IDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHL 366
+A +L+D+ K GY P+H+A K +DI L++ D +A + G +HL
Sbjct: 611 QKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHL 670
Query: 367 ACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDEI 543
A + GH+D+V +L+ +++ SNK G P+HLA + +++ ++L++ ++A ++
Sbjct: 671 AAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKM 729
Score = 111 bits (278), Expect = 1e-24
Identities = 47/166 (28%), Positives = 90/166 (54%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGY 186
L++ D +A G +HLA + GH+++V +L+ + ++ NK+G P+HLA +
Sbjct: 650 LLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDR 709
Query: 187 IDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHL 366
+++A++L+++ + K GY P+H+ C G+I I+ L+ ++A K GY P+H
Sbjct: 710 VNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQ 769
Query: 367 ACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKIL 504
A + GH I+ +L+ N + G + +A G+I ++ L
Sbjct: 770 AAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 815
Score = 110 bits (276), Expect = 2e-24
Identities = 48/174 (27%), Positives = 90/174 (51%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGY 186
L+ +A +GY P+HL+ GH ++ L+D +S K G+ P+H+A + G
Sbjct: 518 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 577
Query: 187 IDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHL 366
+++A +L+ K K G P+H+A + + +L+D+ A+ K GY P+H+
Sbjct: 578 LEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHI 637
Query: 367 ACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
A + +DI L++ D + + G +HLA + GH+D++ +L+ +N
Sbjct: 638 AAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVN 691
Score = 110 bits (275), Expect = 3e-24
Identities = 49/176 (27%), Positives = 95/176 (53%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K+L+D I A +G P+H +GH ++V++L+D+ I + KNG P+H+A +
Sbjct: 285 KLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQG 344
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
+++ ++L+ + +H+A GH + K+L+DKK + +A G+ P+
Sbjct: 345 DHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPL 404
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
H+AC+ I ++++L+ + I + G PIH+A GH++I+ L+ + N
Sbjct: 405 HIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPN 460
Score = 108 bits (269), Expect = 1e-23
Identities = 49/176 (27%), Positives = 95/176 (53%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K+L+D K + +A NG+ P+H+AC+ I+++++L+ I A ++G PIH+A
Sbjct: 384 KVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFM 443
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G+++I L+ +T N G +H+A ++G ++++ L+ + A K P+
Sbjct: 444 GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPL 503
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
H++ G DIV+ L+ + + GY P+HL+ GH D+ L+D+ ++
Sbjct: 504 HISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLS 559
Score = 106 bits (265), Expect = 4e-23
Identities = 45/173 (26%), Positives = 94/173 (54%)
Frame = +1
Query: 13 DNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYID 192
DN D+ + ++G+ P+H+A G+I + +L+++ + +N P+H+A + G +
Sbjct: 225 DNNADVES--KSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNAN 282
Query: 193 IAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLAC 372
+ K+L+D+ I + G P+H ++GH ++++L+D+ I + K G P+H+A
Sbjct: 283 MVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMAT 342
Query: 373 ENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
+ H++ V++L+ + + +H+A GH + K+L+D K NA
Sbjct: 343 QGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNA 395
Score = 103 bits (258), Expect = 3e-22
Identities = 45/179 (25%), Positives = 94/179 (52%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L++ + N P+H+A + G+ +VK+L+D+ I A ++G P+H +G
Sbjct: 253 LLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSG 312
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
+ + ++L+D+ I + K G P+H+A + H++ +++L+ + +H
Sbjct: 313 HEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALH 372
Query: 364 LACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
+A GH + K+L+D K + + G+ P+H+AC+ I +M++L+ + I A E
Sbjct: 373 VAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTE 431
Score = 103 bits (256), Expect = 4e-22
Identities = 48/177 (27%), Positives = 91/177 (51%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
+ L+ + + A ++ P+H++ G +IV+ L+ + +A +GY P+HL+
Sbjct: 483 RYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSARE 542
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G+ D+A L+D +S K G+ P+H+A K G +++ +L+ K A+ K G P+
Sbjct: 543 GHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPL 602
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
H+A + + +L+D + K GY P+H+A + +DI L++ NA
Sbjct: 603 HVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANA 659
Score = 102 bits (255), Expect = 6e-22
Identities = 47/202 (23%), Positives = 101/202 (50%), Gaps = 29/202 (14%)
Frame = +1
Query: 10 IDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYI 189
I N DI+ N+NG +HLA + GH+E+V L+ ++ + A K G +H+A G
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 120
Query: 190 DIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLA 369
++ K+L+ +++ ++ G+ P+++A + H++++K L+D S + + G+ P+ +A
Sbjct: 121 EVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVA 180
Query: 370 CENGHIDIVKILIDNKC-----------------------------DISTSNKYGYQPIH 462
+ GH +V +L++N + +K G+ P+H
Sbjct: 181 LQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLH 240
Query: 463 LACENGHIDIMKILIDNKCGIN 528
+A G+I++ +L++ ++
Sbjct: 241 IAAHYGNINVATLLLNRAAAVD 262
Score = 102 bits (254), Expect = 8e-22
Identities = 47/177 (26%), Positives = 91/177 (51%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+ + I A E+G PIH+A GH+ IV L+ + N G +H+A +
Sbjct: 417 ELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARS 476
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G ++ + L+ + K P+H++ + G DI++ L+ + +A+ GY P+
Sbjct: 477 GQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPL 536
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
HL+ GH D+ L+D+ +S + K G+ P+H+A + G +++ +L+ +A
Sbjct: 537 HLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDA 593
Score = 101 bits (252), Expect = 1e-21
Identities = 50/205 (24%), Positives = 105/205 (51%), Gaps = 29/205 (14%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKC---------YISAY----- 138
K L+DN S E+G+ P+ +A + GH ++V +L++ +I+A
Sbjct: 157 KFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTK 216
Query: 139 ---------------NKNGYQPIHLACENGYIDIAKILIDKKCDISTFNKYGYQPIHLAC 273
+K+G+ P+H+A G I++A +L+++ + + P+H+A
Sbjct: 217 AAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVAS 276
Query: 274 KNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQ 453
K G+ +++K+L+D+ I A + G P+H +GH +V++L+D I + K G
Sbjct: 277 KRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLS 336
Query: 454 PIHLACENGHIDIMKILIDNKCGIN 528
P+H+A + H++ +++L+ + ++
Sbjct: 337 PLHMATQGDHLNCVQLLLQHNVPVD 361
Score = 100 bits (248), Expect = 4e-21
Identities = 47/206 (22%), Positives = 103/206 (50%), Gaps = 31/206 (15%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K+L+ N +++A ++NG+ P+++A + H+E+VK L+D S ++G+ P+ +A +
Sbjct: 124 KVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQ 183
Query: 181 GYIDIAKILI-------------------------------DKKCDISTFNKYGYQPIHL 267
G+ + +L+ D D+ +K G+ P+H+
Sbjct: 184 GHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVE--SKSGFTPLHI 241
Query: 268 ACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDISTSNKYG 447
A G+I++ +L+++ + + + P+H+A + G+ ++VK+L+D I + G
Sbjct: 242 AAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDG 301
Query: 448 YQPIHLACENGHIDIMKILIDNKCGI 525
P+H +GH ++++L+D I
Sbjct: 302 LTPLHCGARSGHEQVVEMLLDRAAPI 327
Score = 96.7 bits (239), Expect = 4e-20
Identities = 45/177 (25%), Positives = 89/177 (50%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+ + + + +H+A GH ++ K+L+DKK +A NG+ P+H+AC+
Sbjct: 351 QLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKK 410
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
I + ++L+ I + G PIH+A GH++I+ L+ + +N G +
Sbjct: 411 NRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETAL 470
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
H+A +G ++V+ L+ + + K P+H++ G DI++ L+ NA
Sbjct: 471 HMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNA 527
Score = 96.3 bits (238), Expect = 5e-20
Identities = 39/148 (26%), Positives = 85/148 (57%)
Frame = +1
Query: 70 ACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILIDKKCDISTFNKYG 249
A GH+E I I+ N+NG +HLA + G++++ L+ ++ ++ K G
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 250 YQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDIS 429
+H+A G +++K+L+ +++A ++ G+ P+++A + H+++VK L+DN S
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 430 TSNKYGYQPIHLACENGHIDIMKILIDN 513
+ + G+ P+ +A + GH ++ +L++N
Sbjct: 168 LATEDGFTPLAVALQQGHDQVVSLLLEN 195
Score = 94.0 bits (232), Expect = 3e-19
Identities = 41/157 (26%), Positives = 79/157 (50%)
Frame = +1
Query: 40 NENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILIDKK 219
N G +H+A +G E+V+ L+ + A K+ P+H++ G DI + L+ +
Sbjct: 463 NVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG 522
Query: 220 CDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVK 399
+ GY P+HL+ + GH D+ L+D +S + K G+ P+H+A + G +++
Sbjct: 523 ASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVAN 582
Query: 400 ILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILID 510
+L+ + K G P+H+A + + +L+D
Sbjct: 583 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD 619
Score = 82.8 bits (203), Expect = 6e-16
Identities = 35/134 (26%), Positives = 68/134 (50%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L+ +++ N++G P+HLA + + + ++L+++ ++ A K GY P+H+ C G
Sbjct: 682 LLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG 741
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
I I L+ ++ K GY P+H A + GH I+ +L+ + G +
Sbjct: 742 NIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALG 801
Query: 364 LACENGHIDIVKIL 405
+A G+I +V L
Sbjct: 802 IARRLGYISVVDTL 815
Score = 65.1 bits (157), Expect = 1e-10
Identities = 28/102 (27%), Positives = 53/102 (51%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L++ + A + GY P+H+ C G+I+IV L+ ++A KNGY P+H A +
Sbjct: 714 EVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQ 773
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKIL 306
G+ I +L+ + G + +A + G+I ++ L
Sbjct: 774 GHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 815
Score = 59.3 bits (142), Expect = 7e-09
Identities = 25/91 (27%), Positives = 49/91 (53%)
Frame = +1
Query: 268 ACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDISTSNKYG 447
A + GH++ I DI+ N+ G +HLA + GH+++V L+ + ++ + K G
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 448 YQPIHLACENGHIDIMKILIDNKCGINAHDE 540
+H+A G +++K+L+ N +NA +
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQ 138
>sp|P16157|ANK1_HUMAN Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin R)
Length = 1881
Score = 123 bits (308), Expect = 4e-28
Identities = 52/161 (32%), Positives = 93/161 (57%)
Frame = +1
Query: 46 NGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILIDKKCD 225
NGY P+H+A + +E+ + L+ +A + G P+HLA + G+ ++ +L+ K+ +
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660
Query: 226 ISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKIL 405
+ NK G P+HL + GH+ + +LI + A+ + GY P+H+A G+I +VK L
Sbjct: 661 GNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 720
Query: 406 IDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
+ ++ D++ K GY P+H A + GH DI+ +L+ N N
Sbjct: 721 LQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPN 761
Score = 122 bits (305), Expect = 9e-28
Identities = 58/177 (32%), Positives = 98/177 (55%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
+IL+D+ I A +NG PIH+A + H++ V++L+ I + P+H+A
Sbjct: 289 EILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHC 348
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G+ +AK+L+DK ++ G+ P+H+ACK H+ +M++L+ I A + G P+
Sbjct: 349 GHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPL 408
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
H+A GH+ IVK L+ + SN P+H+A GH ++ K L+ NK +NA
Sbjct: 409 HVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNA 465
Score = 116 bits (290), Expect = 5e-26
Identities = 55/173 (31%), Positives = 97/173 (56%), Gaps = 3/173 (1%)
Frame = +1
Query: 31 SAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILI 210
+A + G P+HLA + GH E+V +L+ K+ + NK+G P+HL + G++ +A +LI
Sbjct: 629 NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 688
Query: 211 DKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHID 390
+ + GY P+H+A G+I ++K L+ + D++A K GY P+H A + GH D
Sbjct: 689 KHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTD 748
Query: 391 IVKILIDNKCDISTSNKYGYQPIHLACENGHI---DIMKILIDNKCGINAHDE 540
IV +L+ N + + G P+ +A G+I D++K++ D + D+
Sbjct: 749 IVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDK 801
Score = 115 bits (289), Expect = 7e-26
Identities = 49/181 (27%), Positives = 105/181 (58%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L++ +A +NG P+H+A + +++IVK+L+ + + NGY P+H+A +
Sbjct: 553 ELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQ 612
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
+++A+ L+ + + G P+HLA + GH +++ +L+ K+ + + NK G P+
Sbjct: 613 NQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPL 672
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
HL + GH+ + +LI + + + + GY P+H+A G+I ++K L+ ++ +NA +
Sbjct: 673 HLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTK 732
Query: 541 I 543
+
Sbjct: 733 L 733
Score = 115 bits (288), Expect = 9e-26
Identities = 51/180 (28%), Positives = 99/180 (55%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L++ ++ +NG P+H+A G++ +V++L+D+ I K+ P+H A N
Sbjct: 223 QLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARN 282
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G++ I++IL+D I K G PIH+A + H+D +++L+ +I P+
Sbjct: 283 GHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPL 342
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
H+A GH + K+L+D ++ G+ P+H+AC+ H+ +M++L+ I+A E
Sbjct: 343 HVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTE 402
Score = 113 bits (283), Expect = 3e-25
Identities = 52/176 (29%), Positives = 92/176 (52%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+D I ++ P+H A NGH+ I +IL+D I A KNG PIH+A +
Sbjct: 256 RLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQG 315
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
++D ++L+ +I P+H+A GH + K+L+DK ++ G+ P+
Sbjct: 316 DHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPL 375
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
H+AC+ H+ ++++L+ I + G P+H+A GH+ I+K L+ N
Sbjct: 376 HIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 431
Score = 113 bits (283), Expect = 3e-25
Identities = 48/172 (27%), Positives = 97/172 (56%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K+L+D ++ NG+ P+H+AC+ H+ ++++L+ I A ++G P+H+A
Sbjct: 355 KVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFM 414
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G++ I K L+ + + N P+H+A + GH ++ K L+ K ++A K P+
Sbjct: 415 GHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPL 474
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNK 516
H A GH ++VK+L++N + + + G+ P+H+A GH++ + L++ +
Sbjct: 475 HCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKE 526
Score = 111 bits (278), Expect = 1e-24
Identities = 49/169 (28%), Positives = 93/169 (55%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L+ N + ++ G+ P+H+A ++ + ++L+++ ++ +NG P+H+A G
Sbjct: 191 VLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRG 250
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
+ + ++L+D+ I T K P+H A +NGH+ I +IL+D I A K G PIH
Sbjct: 251 NVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIH 310
Query: 364 LACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILID 510
+A + H+D V++L+ +I P+H+A GH + K+L+D
Sbjct: 311 MAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLD 359
Score = 109 bits (273), Expect = 5e-24
Identities = 49/176 (27%), Positives = 93/176 (52%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+ +I + P+H+A GH + K+L+DK ++ NG+ P+H+AC+
Sbjct: 322 RLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKK 381
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
++ + ++L+ I + G P+H+A GH+ I+K L+ + + SN P+
Sbjct: 382 NHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPL 441
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
H+A GH ++ K L+ NK ++ K P+H A GH +++K+L++N N
Sbjct: 442 HMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPN 497
Score = 107 bits (266), Expect = 3e-23
Identities = 48/177 (27%), Positives = 96/177 (54%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+ I A E+G P+H+A GH+ IVK L+ + + N P+H+A
Sbjct: 388 ELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARA 447
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G+ ++AK L+ K ++ K P+H A + GH +++K+L++ + + + G+ P+
Sbjct: 448 GHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPL 507
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
H+A GH++ V L++ + + K G+ P+H+A + G + + ++L++ NA
Sbjct: 508 HIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNA 564
Score = 106 bits (264), Expect = 5e-23
Identities = 47/177 (26%), Positives = 96/177 (54%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K L+ NK ++A ++ P+H A GH +VK+L++ + G+ P+H+A
Sbjct: 454 KYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAARE 513
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G+++ L++K+ + K G+ P+H+A K G + + ++L+++ +A+ K G P+
Sbjct: 514 GHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPL 573
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
H+A + ++DIVK+L+ + GY P+H+A + +++ + L+ NA
Sbjct: 574 HVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANA 630
Score = 104 bits (260), Expect = 2e-22
Identities = 41/150 (27%), Positives = 88/150 (58%)
Frame = +1
Query: 58 PIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILIDKKCDISTF 237
P+H+A GH E+ K L+ K ++A K+ P+H A G+ ++ K+L++ + +
Sbjct: 440 PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLA 499
Query: 238 NKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNK 417
G+ P+H+A + GH++ + L++K+ + K G+ P+H+A + G + + ++L++
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 559
Query: 418 CDISTSNKYGYQPIHLACENGHIDIMKILI 507
+ + K G P+H+A + ++DI+K+L+
Sbjct: 560 AHPNAAGKNGLTPLHVAVHHNNLDIVKLLL 589
Score = 100 bits (249), Expect = 3e-21
Identities = 51/198 (25%), Positives = 101/198 (51%), Gaps = 29/198 (14%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILID---------KKCYISAYN---- 141
K L++N + + E+G+ P+ +A + GH +V LI+ +I+A N
Sbjct: 128 KFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTR 187
Query: 142 ----------------KNGYQPIHLACENGYIDIAKILIDKKCDISTFNKYGYQPIHLAC 273
K G+ P+H+A +++A++L+++ ++ + G P+H+A
Sbjct: 188 TAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIAS 247
Query: 274 KNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQ 453
+ G++ ++++L+D+ I K P+H A NGH+ I +IL+D+ I K G
Sbjct: 248 RRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLS 307
Query: 454 PIHLACENGHIDIMKILI 507
PIH+A + H+D +++L+
Sbjct: 308 PIHMAAQGDHLDCVRLLL 325
Score = 96.3 bits (238), Expect = 5e-20
Identities = 45/204 (22%), Positives = 104/204 (50%), Gaps = 29/204 (14%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGY 186
L++ +++A ++ G+ P+++A + H+E+VK L++ + ++G+ P+ +A + G+
Sbjct: 97 LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGH 156
Query: 187 IDI-----------------------------AKILIDKKCDISTFNKYGYQPIHLACKN 279
++ A +L+ + +K G+ P+H+A
Sbjct: 157 ENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHY 216
Query: 280 GHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQPI 459
++++ ++L+++ ++ + + G P+H+A G++ +V++L+D I T K P+
Sbjct: 217 ENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 276
Query: 460 HLACENGHIDIMKILIDNKCGINA 531
H A NGH+ I +IL+D+ I A
Sbjct: 277 HCAARNGHVRISEILLDHGAPIQA 300
Score = 90.1 bits (222), Expect = 4e-18
Identities = 42/150 (28%), Positives = 80/150 (53%), Gaps = 3/150 (2%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L+ + + + N++G P+HL + GH+ + +LI + A + GY P+H+A G
Sbjct: 653 LLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYG 712
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
I + K L+ + D++ K GY P+H A + GH DI+ +L+ + + G P+
Sbjct: 713 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLA 772
Query: 364 LACENGHI---DIVKILIDNKCDISTSNKY 444
+A G+I D++K++ D + S+K+
Sbjct: 773 IAKRLGYISVTDVLKVVTDETSFVLVSDKH 802
Score = 88.2 bits (217), Expect = 1e-17
Identities = 41/166 (24%), Positives = 89/166 (53%)
Frame = +1
Query: 16 NKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDI 195
N DI+ N+NG +HLA + GH+++V L+ K+ + K G +H+A G ++
Sbjct: 34 NGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEV 93
Query: 196 AKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACE 375
+ L++ +++ ++ G+ P+++A + H++++K L++ + + + + G+ P+ +A +
Sbjct: 94 VRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQ 153
Query: 376 NGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDN 513
GH ++V LI + T K +H+A N +L+ N
Sbjct: 154 QGHENVVAHLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQN 195
Score = 72.0 bits (175), Expect = 1e-12
Identities = 33/124 (26%), Positives = 69/124 (55%)
Frame = +1
Query: 169 ACENGYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYG 348
A +G +D A + DI+T N+ G +HLA K GH+ ++ L+ K+ + + K G
Sbjct: 19 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG 78
Query: 349 YQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
+H+A G ++V+ L++ +++ ++ G+ P+++A + H++++K L++N N
Sbjct: 79 NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQN 138
Query: 529 AHDE 540
E
Sbjct: 139 VATE 142
Score = 50.1 bits (118), Expect = 4e-06
Identities = 24/85 (28%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K L+ ++ D++A + GY P+H A + GH +IV +L+ + + +G P+ +A
Sbjct: 718 KFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRL 777
Query: 181 GYI---DIAKILIDKKCDISTFNKY 246
GYI D+ K++ D+ + +K+
Sbjct: 778 GYISVTDVLKVVTDETSFVLVSDKH 802
>sp|Q02357|ANK1_MOUSE Ankyrin-1 (Erythrocyte ankyrin)
Length = 1862
Score = 122 bits (307), Expect = 5e-28
Identities = 53/161 (32%), Positives = 93/161 (57%)
Frame = +1
Query: 46 NGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILIDKKCD 225
NGY P+H+A + IE+ + L+ +A + G P+HLA + G+ ++ +L+ K+ +
Sbjct: 597 NGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQAN 656
Query: 226 ISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKIL 405
+ NK G P+HL + GH+ + +LI + A+ + GY P+H+A G+I +VK L
Sbjct: 657 GNLGNKSGLTPLHLVSQEGHVLVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFL 716
Query: 406 IDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
+ ++ D++ K GY P+H A + GH DI+ +L+ N N
Sbjct: 717 LQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPN 757
Score = 121 bits (303), Expect = 2e-27
Identities = 59/177 (33%), Positives = 97/177 (54%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
+IL+D+ I A +NG PIH+A + H++ V++L+ I + P+H+A
Sbjct: 285 EILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHC 344
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G+ +AK+L+DK ++ G+ P+H+ACK HI +M++L+ I A + G P+
Sbjct: 345 GHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPL 404
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
H+A GH+ IVK L+ + SN P+H+A GH ++ K L+ NK NA
Sbjct: 405 HVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKANA 461
Score = 116 bits (290), Expect = 5e-26
Identities = 52/180 (28%), Positives = 99/180 (55%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L++ ++ +NG P+H+A G++ +V++L+D+ I K+ P+H A N
Sbjct: 219 QLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARN 278
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G++ I++IL+D I K G PIH+A + H+D +++L+ +I P+
Sbjct: 279 GHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPL 338
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
H+A GH + K+L+D ++ G+ P+H+AC+ HI +M++L+ I+A E
Sbjct: 339 HVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTE 398
Score = 115 bits (289), Expect = 7e-26
Identities = 50/181 (27%), Positives = 106/181 (58%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+++ +A +NG P+H+A + +++IVK+L+ + + NGY P+H+A +
Sbjct: 549 ELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQ 608
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
I++A+ L+ + + G P+HLA + GH +++ +L+ K+ + + NK G P+
Sbjct: 609 NQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPL 668
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
HL + GH+ + +LI + + + + GY P+H+A G+I ++K L+ ++ +NA +
Sbjct: 669 HLVSQEGHVLVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTK 728
Query: 541 I 543
+
Sbjct: 729 L 729
Score = 115 bits (289), Expect = 7e-26
Identities = 55/173 (31%), Positives = 97/173 (56%), Gaps = 3/173 (1%)
Frame = +1
Query: 31 SAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILI 210
+A + G P+HLA + GH E+V +L+ K+ + NK+G P+HL + G++ +A +LI
Sbjct: 625 NAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVLVADVLI 684
Query: 211 DKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHID 390
+ + GY P+H+A G+I ++K L+ + D++A K GY P+H A + GH D
Sbjct: 685 KHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTD 744
Query: 391 IVKILIDNKCDISTSNKYGYQPIHLACENGHI---DIMKILIDNKCGINAHDE 540
IV +L+ N + + G P+ +A G+I D++K++ D + D+
Sbjct: 745 IVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVLKVVTDETSVVLVSDK 797
Score = 114 bits (285), Expect = 2e-25
Identities = 53/176 (30%), Positives = 92/176 (52%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+D I ++ P+H A NGH+ I +IL+D I A KNG PIH+A +
Sbjct: 252 RLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQG 311
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
++D ++L+ +I P+H+A GH + K+L+DK ++ G+ P+
Sbjct: 312 DHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPL 371
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
H+AC+ HI ++++L+ I + G P+H+A GH+ I+K L+ N
Sbjct: 372 HIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 427
Score = 112 bits (279), Expect = 1e-24
Identities = 49/169 (28%), Positives = 93/169 (55%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L+ N + ++ G+ P+H+A ++ + ++L+++ ++ +NG P+H+A G
Sbjct: 187 VLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRG 246
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
+ + ++L+D+ I T K P+H A +NGH+ I +IL+D I A K G PIH
Sbjct: 247 NVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIH 306
Query: 364 LACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILID 510
+A + H+D V++L+ +I P+H+A GH + K+L+D
Sbjct: 307 MAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLD 355
Score = 110 bits (274), Expect = 4e-24
Identities = 50/172 (29%), Positives = 92/172 (53%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K+L+D ++ NG+ P+H+AC+ HI ++++L+ I A ++G P+H+A
Sbjct: 351 KVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFM 410
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G++ I K L+ + + N P+H+A + GH ++ K L+ K +A K P+
Sbjct: 411 GHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPL 470
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNK 516
H A GH +VK+L++N + + G+ P+H A GH+D L++ +
Sbjct: 471 HCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKE 522
Score = 107 bits (267), Expect = 2e-23
Identities = 50/176 (28%), Positives = 91/176 (51%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+ +I + P+H+A GH + K+L+DK ++ NG+ P+H+AC+
Sbjct: 318 RLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKK 377
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
+I + ++L+ I + G P+H+A GH+ I+K L+ + + SN P+
Sbjct: 378 NHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPL 437
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
H+A GH ++ K L+ NK + K P+H A GH ++K+L++N N
Sbjct: 438 HMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKLLLENGASPN 493
Score = 103 bits (258), Expect = 3e-22
Identities = 50/177 (28%), Positives = 94/177 (53%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K L+ NK +A ++ P+H A GH +VK+L++ + G+ P+H A
Sbjct: 450 KYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAARE 509
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G++D A L++K+ + K G+ P+H+A K G + + ++L++ +A+ K G P+
Sbjct: 510 GHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPL 569
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
H+A + ++DIVK+L+ + GY P+H+A + I++ + L+ NA
Sbjct: 570 HVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANA 626
Score = 102 bits (254), Expect = 8e-22
Identities = 48/177 (27%), Positives = 92/177 (51%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+ I A E+G P+H+A GH+ IVK L+ + + N P+H+A
Sbjct: 384 ELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARA 443
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G+ ++AK L+ K + K P+H A + GH ++K+L++ + + G+ P+
Sbjct: 444 GHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPL 503
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
H A GH+D L++ + + K G+ P+H+A + G + + ++L+++ NA
Sbjct: 504 HTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNA 560
Score = 100 bits (250), Expect = 2e-21
Identities = 42/150 (28%), Positives = 84/150 (56%)
Frame = +1
Query: 58 PIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILIDKKCDISTF 237
P+H+A GH E+ K L+ K +A K+ P+H A G+ + K+L++ +
Sbjct: 436 PLHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKLLLENGASPNLA 495
Query: 238 NKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNK 417
G+ P+H A + GH+D L++K+ + K G+ P+H+A + G + + ++L+++
Sbjct: 496 TTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHD 555
Query: 418 CDISTSNKYGYQPIHLACENGHIDIMKILI 507
+ + K G P+H+A + ++DI+K+L+
Sbjct: 556 AHPNAAGKNGLTPLHVAVHHNNLDIVKLLL 585
Score = 100 bits (249), Expect = 3e-21
Identities = 52/205 (25%), Positives = 103/205 (50%), Gaps = 29/205 (14%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILID---------KKCYISAYN---- 141
K L++N + + E+G+ P+ +A + GH +V LI+ +I+A N
Sbjct: 124 KFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTR 183
Query: 142 ----------------KNGYQPIHLACENGYIDIAKILIDKKCDISTFNKYGYQPIHLAC 273
K G+ P+H+A +++A++L+++ ++ + G P+H+A
Sbjct: 184 TAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIAS 243
Query: 274 KNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQ 453
+ G++ ++++L+D+ I K P+H A NGH+ I +IL+D+ I K G
Sbjct: 244 RRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLS 303
Query: 454 PIHLACENGHIDIMKILIDNKCGIN 528
PIH+A + H+D +++L+ I+
Sbjct: 304 PIHMAAQGDHLDCVRLLLQYNAEID 328
Score = 95.9 bits (237), Expect = 7e-20
Identities = 45/204 (22%), Positives = 104/204 (50%), Gaps = 29/204 (14%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGY 186
L++ +++A ++ G+ P+++A + H+E+VK L++ + ++G+ P+ +A + G+
Sbjct: 93 LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGH 152
Query: 187 IDI-----------------------------AKILIDKKCDISTFNKYGYQPIHLACKN 279
++ A +L+ + +K G+ P+H+A
Sbjct: 153 ENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHY 212
Query: 280 GHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQPI 459
++++ ++L+++ ++ + + G P+H+A G++ +V++L+D I T K P+
Sbjct: 213 ENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPL 272
Query: 460 HLACENGHIDIMKILIDNKCGINA 531
H A NGH+ I +IL+D+ I A
Sbjct: 273 HCAARNGHVRISEILLDHGAPIQA 296
Score = 89.0 bits (219), Expect = 9e-18
Identities = 42/150 (28%), Positives = 80/150 (53%), Gaps = 3/150 (2%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L+ + + + N++G P+HL + GH+ + +LI + A + GY P+H+A G
Sbjct: 649 LLLSKQANGNLGNKSGLTPLHLVSQEGHVLVADVLIKHGVTVDATTRMGYTPLHVASHYG 708
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
I + K L+ + D++ K GY P+H A + GH DI+ +L+ + + G P+
Sbjct: 709 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLA 768
Query: 364 LACENGHI---DIVKILIDNKCDISTSNKY 444
+A G+I D++K++ D + S+K+
Sbjct: 769 IAKRLGYISVTDVLKVVTDETSVVLVSDKH 798
Score = 88.2 bits (217), Expect = 1e-17
Identities = 41/166 (24%), Positives = 89/166 (53%)
Frame = +1
Query: 16 NKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDI 195
N DI+ N+NG +HLA + GH+++V L+ K+ + K G +H+A G ++
Sbjct: 30 NGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEV 89
Query: 196 AKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACE 375
+ L++ +++ ++ G+ P+++A + H++++K L++ + + + + G+ P+ +A +
Sbjct: 90 VRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQ 149
Query: 376 NGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDN 513
GH ++V LI + T K +H+A N +L+ N
Sbjct: 150 QGHENVVAHLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQN 191
Score = 72.0 bits (175), Expect = 1e-12
Identities = 33/124 (26%), Positives = 69/124 (55%)
Frame = +1
Query: 169 ACENGYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYG 348
A +G +D A + DI+T N+ G +HLA K GH+ ++ L+ K+ + + K G
Sbjct: 15 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG 74
Query: 349 YQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
+H+A G ++V+ L++ +++ ++ G+ P+++A + H++++K L++N N
Sbjct: 75 NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQN 134
Query: 529 AHDE 540
E
Sbjct: 135 VATE 138
Score = 52.0 bits (123), Expect = 1e-06
Identities = 25/85 (29%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K L+ ++ D++A + GY P+H A + GH +IV +L+ + + NG P+ +A
Sbjct: 714 KFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRL 773
Query: 181 GYI---DIAKILIDKKCDISTFNKY 246
GYI D+ K++ D+ + +K+
Sbjct: 774 GYISVTDVLKVVTDETSVVLVSDKH 798
>sp|O15084|ANR28_HUMAN Ankyrin repeat domain protein 28
Length = 1086
Score = 112 bits (281), Expect = 6e-25
Identities = 52/180 (28%), Positives = 103/180 (57%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+ + D++A ++N P+H+A N ++ + L+ ++ ++ G +H A +
Sbjct: 124 QVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFS 183
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G+ ++ K+L+ + +I+ F+K + IH A GHI+++K+L+ +++ +K Y P+
Sbjct: 184 GHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPL 243
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
H A +G I +VK L+D D++ N YG P+H+AC NG ++ LID +N +E
Sbjct: 244 HAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNE 303
Score = 112 bits (279), Expect = 1e-24
Identities = 54/181 (29%), Positives = 100/181 (55%), Gaps = 1/181 (0%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K+L+ +I+A+++ + IH A GHIE+VK+L+ ++ +K Y P+H A +
Sbjct: 190 KLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASS 249
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G I + K L+D D++ N YG P+H+AC NG ++ LID ++ N+ G+ P+
Sbjct: 250 GMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPL 309
Query: 361 HLACENGHIDI-VKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHD 537
H A + H + +++L+ N D++ +K G P+H+ +G + +I + I+ D
Sbjct: 310 HFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCED 369
Query: 538 E 540
+
Sbjct: 370 K 370
Score = 108 bits (269), Expect = 1e-23
Identities = 52/169 (30%), Positives = 97/169 (57%), Gaps = 1/169 (0%)
Frame = +1
Query: 25 DISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKI 204
+++ + G +H A +GH E+VK+L+ + I+A++K + IH A G+I++ K+
Sbjct: 165 NVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKL 224
Query: 205 LIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGH 384
L+ +++ +K Y P+H A +G I ++K L+D D++ N YG P+H+AC NG
Sbjct: 225 LVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQ 284
Query: 385 IDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDI-MKILIDNKCGIN 528
+V LID ++ N+ G+ P+H A + H + +++L+ N +N
Sbjct: 285 DVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVN 333
Score = 97.1 bits (240), Expect = 3e-20
Identities = 47/170 (27%), Positives = 97/170 (57%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++LI + ++A + P+H A + E V++L+ ++A +KN P+H+A N
Sbjct: 91 ELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAAN 150
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
+ A+ L+ +++ ++ G +H A +GH +++K+L+ + +I+A +K + I
Sbjct: 151 KAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAI 210
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILID 510
H A GHI++VK+L+ + +++ +K Y P+H A +G I ++K L+D
Sbjct: 211 HWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLD 260
Score = 91.7 bits (226), Expect = 1e-18
Identities = 45/180 (25%), Positives = 88/180 (48%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+ N D++ +++G P+H+ +G + +I I +KNG P+H+A
Sbjct: 323 ELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARY 382
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G+ + LI D + +G P+HLA +G D + L+ DI + +G +
Sbjct: 383 GHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCL 442
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
H A G+++ + +L++ D + +K+G P+H A N + + L+ + +N DE
Sbjct: 443 HAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDE 502
Score = 86.7 bits (213), Expect = 4e-17
Identities = 46/179 (25%), Positives = 90/179 (50%), Gaps = 1/179 (0%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHIEI-VKILIDKKCYISAYNKNGYQPIHLACENG 183
LID ++ NE G+ P+H A + H + +++L+ ++ +K+G P+H+ +G
Sbjct: 291 LIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHG 350
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
++ +I I +K G P+H+A + GH ++ LI D + +G P+H
Sbjct: 351 RFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLH 410
Query: 364 LACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
LA +G D + L+ + DI T + +G +H A G+++ + +L++ N D+
Sbjct: 411 LAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDK 469
Score = 85.9 bits (211), Expect = 7e-17
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 6/184 (3%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQ-PIHLACE 177
++L+ + D+ N +G P+ LA GH+E V +LI++ I + + PIH A
Sbjct: 600 EVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAAT 659
Query: 178 NGYIDIAKILI-----DKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNK 342
NG+ + ++LI DI N G P+ L+ NGH D + L++K ++ A +K
Sbjct: 660 NGHSECLRLLIGNAEPQNAVDIQDGN--GQTPLMLSVLNGHTDCVYSLLNKGANVDAKDK 717
Query: 343 YGYQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCG 522
+G +H GH + V L+ + + G PIHL+ GHI ++ L+ +
Sbjct: 718 WGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAAS 777
Query: 523 INAH 534
++A+
Sbjct: 778 MDAN 781
Score = 84.0 bits (206), Expect = 3e-16
Identities = 44/180 (24%), Positives = 92/180 (51%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
+ LI K D++ + P+H A G EI+++LI ++A + P+H A +
Sbjct: 58 RALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVAS 117
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
+ ++L+ D++ +K P+H+A N + + L+ +++ S++ G +
Sbjct: 118 CSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTAL 177
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
H A +GH ++VK+L+ +I+ +K + IH A GHI+++K+L+ + + D+
Sbjct: 178 HHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDK 237
Score = 84.0 bits (206), Expect = 3e-16
Identities = 44/160 (27%), Positives = 82/160 (51%), Gaps = 7/160 (4%)
Frame = +1
Query: 58 PIHLACENGHIEIVKILI---DKKCYISAYNKNGYQPIHLACENGYIDIAKILIDKKCDI 228
PIH A NGH E +++LI + + + + NG P+ L+ NG+ D L++K ++
Sbjct: 653 PIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANV 712
Query: 229 STFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILI 408
+K+G +H GH + + L+ + G PIHL+ GHI ++ L+
Sbjct: 713 DAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALL 772
Query: 409 DNKCDI----STSNKYGYQPIHLACENGHIDIMKILIDNK 516
+ + +T++ +GY +H AC NGH +++L++ +
Sbjct: 773 QSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQE 812
Score = 79.0 bits (193), Expect = 9e-15
Identities = 39/154 (25%), Positives = 77/154 (50%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGY 186
+I + I ++NG P+H+A GH ++ LI + +G P+HLA +G+
Sbjct: 358 IIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGF 417
Query: 187 IDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHL 366
D + L+ DI T + +G +H A G+++ + +L++ D + +K+G P+H
Sbjct: 418 SDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHY 477
Query: 367 ACENGHIDIVKILIDNKCDISTSNKYGYQPIHLA 468
A N + + L+ + ++ ++ G P+H A
Sbjct: 478 AAANCNYQCLFALVGSGASVNDLDERGCTPLHYA 511
Score = 73.9 bits (180), Expect = 3e-13
Identities = 40/164 (24%), Positives = 85/164 (51%), Gaps = 6/164 (3%)
Frame = +1
Query: 40 NENGYQPIHLACENGHIEIVKILIDKKCYISAY----NKNGYQPIHLACENGYIDIAKIL 207
+ G PIHL+ GHI ++ L+ + A + +GY +H AC NG+ ++L
Sbjct: 749 DSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELL 808
Query: 208 IDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDK--KCDISASNKYGYQPIHLACENG 381
++++ T + P+H A N + ++LID ++A++ G P+H A
Sbjct: 809 LEQEVFQKTEGN-AFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTD 867
Query: 382 HIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDN 513
H++ +++L+ + +++ + G P+ +A ENG + +++L+ +
Sbjct: 868 HVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSS 911
Score = 73.6 bits (179), Expect = 4e-13
Identities = 42/183 (22%), Positives = 87/183 (47%), Gaps = 6/183 (3%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGY 186
L++ ++ A ++ G +H GH E V L+ + G PIHL+ G+
Sbjct: 705 LLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGH 764
Query: 187 IDIAKILIDKKCDI----STFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQ 354
I + L+ + +T + +GY +H AC NGH +++L++++ + +
Sbjct: 765 IGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEV-FQKTEGNAFS 823
Query: 355 PIHLACENGHIDIVKILIDN--KCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
P+H A N + ++LID ++ ++ G P+H A H++ +++L+ + +N
Sbjct: 824 PLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVN 883
Query: 529 AHD 537
+ D
Sbjct: 884 SVD 886
Score = 71.2 bits (173), Expect = 2e-12
Identities = 39/152 (25%), Positives = 77/152 (50%), Gaps = 4/152 (2%)
Frame = +1
Query: 28 ISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKIL 207
++A + G P+H A H+E +++L+ +++ + G P+ +A ENG + ++L
Sbjct: 849 VNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEML 908
Query: 208 IDK-KCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCD---ISASNKYGYQPIHLACE 375
+ +++ + +HLAC GH ++++K D I+A+N P+H+A
Sbjct: 909 VSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAAR 968
Query: 376 NGHIDIVKILIDNKCDISTSNKYGYQPIHLAC 471
NG +V+ L+ + ++ GY P LAC
Sbjct: 969 NGLTMVVQELLGKGASVLAVDENGYTPA-LAC 999
Score = 69.7 bits (169), Expect = 5e-12
Identities = 47/191 (24%), Positives = 86/191 (45%), Gaps = 14/191 (7%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHI-EIVKILIDKKCYISAYNKNGYQPIHLACENG 183
L+ + ++ +E G P+H A + + ++ L+ +K GY +H + G
Sbjct: 490 LVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGVRDKQGYNAVHYSAAYG 549
Query: 184 Y-IDIAKILIDKKCDI-----------STFNKYGYQPIHLACKNGHIDIMKILIDKKCDI 327
+ + + I + D+ + N+ P+HLA +GH +++L+ D+
Sbjct: 550 HRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDL 609
Query: 328 SASNKYGYQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQ-PIHLACENGHIDIMKIL 504
N G P+ LA GH++ V +LI+ I + + PIH A NGH + +++L
Sbjct: 610 DVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLL 669
Query: 505 IDNKCGINAHD 537
I N NA D
Sbjct: 670 IGNAEPQNAVD 680
Score = 68.2 bits (165), Expect = 2e-11
Identities = 40/163 (24%), Positives = 81/163 (49%)
Frame = +1
Query: 52 YQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILIDKKCDIS 231
Y + A NG + V+ LI KK ++ + P+H A G +I ++LI ++
Sbjct: 42 YPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVN 101
Query: 232 TFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILID 411
+ P+H A + + +++L+ D++A +K P+H+A N + + L+
Sbjct: 102 AKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVP 161
Query: 412 NKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
+++ S++ G +H A +GH +++K+L+ INA D+
Sbjct: 162 LLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDK 204
Score = 68.2 bits (165), Expect = 2e-11
Identities = 38/171 (22%), Positives = 83/171 (48%), Gaps = 6/171 (3%)
Frame = +1
Query: 46 NGYQPIHLACENGHIEIVKILIDK--KCYISAYNKNGYQPIHLACENGYIDIAKILIDKK 219
N + P+H A N + ++LID ++A + G P+H A +++ ++L+
Sbjct: 820 NAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHN 879
Query: 220 CDISTFNKYGYQPIHLACKNGHIDIMKILIDK-KCDISASNKYGYQPIHLACENGHIDIV 396
+++ + G P+ +A +NG + +++L+ +++ + +HLAC GH
Sbjct: 880 AQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSA 939
Query: 397 KILIDNKCD---ISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
++++ D I+ +N P+H+A NG +++ L+ + A DE
Sbjct: 940 LLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDE 990
Score = 67.8 bits (164), Expect = 2e-11
Identities = 42/194 (21%), Positives = 86/194 (44%), Gaps = 13/194 (6%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L++ D + ++ G P+H A N + + + L+ ++ ++ G P+H A +
Sbjct: 456 LLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSD 515
Query: 184 YID-IAKILIDKKCDISTFNKYGYQPIHLACKNGH-IDIMKILIDKKCDI---------- 327
+ L+ + +K GY +H + GH + + I + D+
Sbjct: 516 TDGKCLEYLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDML 575
Query: 328 -SASNKYGYQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKIL 504
+ N+ P+HLA +GH +++L+ + D+ N G P+ LA GH++ + +L
Sbjct: 576 SDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVL 635
Query: 505 IDNKCGINAHDEIV 546
I+ I D I+
Sbjct: 636 INQGASILVKDYIL 649
>sp|Q01484|ANK2_HUMAN Ankyrin-2 (Brain ankyrin) (Ankyrin B) (Ankyrin, nonerythroid)
Length = 3924
Score = 112 bits (280), Expect = 7e-25
Identities = 50/171 (29%), Positives = 95/171 (55%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K+L+D I A +G P+H A +GH ++V++L+++ + A KNG P+H+A +
Sbjct: 283 KLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQG 342
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
+++ K L+ K + +H+A GH + K+L+DK+ + +A G+ P+
Sbjct: 343 DHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPL 402
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDN 513
H+AC+ I ++++L+ I + G PIH+A GH++I+ +L+ N
Sbjct: 403 HIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQN 453
Score = 112 bits (280), Expect = 7e-25
Identities = 50/178 (28%), Positives = 96/178 (53%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+ + A NGY P+H++ G +++ +L++ S K G+ P+H+A +
Sbjct: 514 QLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKY 573
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G +D+AK+L+ ++ + K G P+H+A + + +L++K A+ K GY P+
Sbjct: 574 GSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPL 633
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAH 534
H+A + + I L++ + + K G P+HLA + GH D++ +L+D G N H
Sbjct: 634 HIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDK--GANIH 689
Score = 112 bits (280), Expect = 7e-25
Identities = 52/177 (29%), Positives = 94/177 (53%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K+L+ + + +NG P+H+A + ++ +L++K A KNGY P+H+A +
Sbjct: 580 KLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKK 639
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
+ IA L++ + + K G P+HLA + GH D++ +L+DK +I S K G +
Sbjct: 640 NQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSL 699
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
HLA + +++ IL + D K GY P+ +AC G++ ++ L+ +NA
Sbjct: 700 HLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNA 756
Score = 111 bits (277), Expect = 2e-24
Identities = 52/176 (29%), Positives = 91/176 (51%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L++ A +NGY P+H+A + ++I L++ + K G P+HLA + G
Sbjct: 614 LLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEG 673
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
+ D+ +L+DK +I K G +HLA + +++ IL D A K GY P+
Sbjct: 674 HTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLI 733
Query: 364 LACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
+AC G++ +V L+ +++ K GY P+H A + GH I+ +L+ + NA
Sbjct: 734 VACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNA 789
Score = 108 bits (270), Expect = 1e-23
Identities = 45/174 (25%), Positives = 96/174 (55%)
Frame = +1
Query: 10 IDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYI 189
+ +K ++ E+G+ P+H+A G++ + +L+++ + +NG P+H+A + G
Sbjct: 220 VQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNT 279
Query: 190 DIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLA 369
++ K+L+D+ I + G P+H A ++GH ++++L+++ + A K G P+H+A
Sbjct: 280 NMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMA 339
Query: 370 CENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
+ H++ VK L+ +K + +H+A GH + K+L+D + NA
Sbjct: 340 AQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNA 393
Score = 108 bits (270), Expect = 1e-23
Identities = 50/177 (28%), Positives = 96/177 (54%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L++ + A +NG P+H+A + H+E VK L+ K + + +H+A
Sbjct: 316 ELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHC 375
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G+ + K+L+DK+ + + G+ P+H+ACK I +M++L+ I A + G PI
Sbjct: 376 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 435
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
H+A GH++IV +L+ N +N G +H+A G +++++ L+ N ++A
Sbjct: 436 HVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDA 492
Score = 106 bits (265), Expect = 4e-23
Identities = 50/180 (27%), Positives = 94/180 (52%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L++ S + G+ P+H+A + G +++ K+L+ ++ + KNG P+H+A
Sbjct: 548 VLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYD 607
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
+A +L++K K GY P+H+A K + I L++ + + K G P+H
Sbjct: 608 NQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLH 667
Query: 364 LACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDEI 543
LA + GH D+V +L+D +I S K G +HLA + +++ IL + +AH ++
Sbjct: 668 LASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKL 727
Score = 103 bits (257), Expect = 3e-22
Identities = 46/179 (25%), Positives = 94/179 (52%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L++ + NG P+H+A + G+ +VK+L+D+ I A ++G P+H A +G
Sbjct: 251 LLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSG 310
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
+ + ++L+++ + K G P+H+A + H++ +K L+ K + +H
Sbjct: 311 HDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALH 370
Query: 364 LACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
+A GH + K+L+D + + + G+ P+H+AC+ I +M++L+ I A E
Sbjct: 371 VAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITE 429
Score = 102 bits (253), Expect = 1e-21
Identities = 46/170 (27%), Positives = 88/170 (51%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
+ L+ N + A P+H+A G EIV++L+ + A NGY P+H++
Sbjct: 481 RCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISARE 540
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G +D+A +L++ S K G+ P+H+A K G +D+ K+L+ ++ ++ K G P+
Sbjct: 541 GQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPL 600
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILID 510
H+A + + +L++ + K GY P+H+A + + I L++
Sbjct: 601 HVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 650
Score = 101 bits (251), Expect = 2e-21
Identities = 43/170 (25%), Positives = 93/170 (54%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K+L+D + + +A NG+ P+H+AC+ I+++++L+ I A ++G PIH+A
Sbjct: 382 KLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFM 441
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G+++I +L+ N G +H+A + G +++++ L+ + A + P+
Sbjct: 442 GHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPL 501
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILID 510
H+A G +IV++L+ + + GY P+H++ G +D+ +L++
Sbjct: 502 HIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLE 551
Score = 98.6 bits (244), Expect = 1e-20
Identities = 46/166 (27%), Positives = 87/166 (52%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGY 186
L++ + + + G P+HLA + GH ++V +L+DK I K+G +HLA +
Sbjct: 648 LLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDK 707
Query: 187 IDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHL 366
+++A IL D K GY P+ +AC G++ ++ L+ + +++A K GY P+H
Sbjct: 708 VNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQ 767
Query: 367 ACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKIL 504
A + GH I+ +L+ + + + G + +A G+I ++ L
Sbjct: 768 AAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 813
Score = 98.2 bits (243), Expect = 1e-20
Identities = 44/177 (24%), Positives = 90/177 (50%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+ I A E+G PIH+A GH+ IV +L+ N G +H+A
Sbjct: 415 ELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARA 474
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G +++ + L+ + + P+H+A + G +I+++L+ A+ GY P+
Sbjct: 475 GQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPL 534
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
H++ G +D+ +L++ S + K G+ P+H+A + G +D+ K+L+ + ++
Sbjct: 535 HISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADS 591
Score = 94.7 bits (234), Expect = 2e-19
Identities = 44/171 (25%), Positives = 88/171 (51%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K L+ +K + + +H+A GH + K+L+DK+ +A NG+ P+H+AC+
Sbjct: 349 KHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKK 408
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
I + ++L+ I + G PIH+A GH++I+ +L+ +N G +
Sbjct: 409 NRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETAL 468
Query: 361 HLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDN 513
H+A G +++V+ L+ N + + P+H+A G +I+++L+ +
Sbjct: 469 HMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQH 519
Score = 94.4 bits (233), Expect = 2e-19
Identities = 44/163 (26%), Positives = 88/163 (53%)
Frame = +1
Query: 25 DISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKI 204
DI+ N+NG +HLA + GH+ +V+ L+ + + + K G +H+A G ++ K+
Sbjct: 56 DINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKV 115
Query: 205 LIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGH 384
L+ + +I+ ++ G+ P+++A + HID++K L++ + S + + G+ P+ +A + GH
Sbjct: 116 LVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGH 175
Query: 385 IDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDN 513
V IL++N T K +H+A +L+ N
Sbjct: 176 NQAVAILLEN----DTKGKVRLPALHIAARKDDTKSAALLLQN 214
Score = 93.2 bits (230), Expect = 5e-19
Identities = 42/168 (25%), Positives = 83/168 (49%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L+ N N G +H+A G +E+V+ L+ + A + P+H+A G
Sbjct: 449 LLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLG 508
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
+I ++L+ GY P+H++ + G +D+ +L++ S + K G+ P+H
Sbjct: 509 KTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLH 568
Query: 364 LACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILI 507
+A + G +D+ K+L+ + ++ K G P+H+A H D K+ +
Sbjct: 569 VAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVA---AHYDNQKVAL 613
Score = 92.8 bits (229), Expect = 6e-19
Identities = 41/148 (27%), Positives = 87/148 (58%)
Frame = +1
Query: 70 ACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILIDKKCDISTFNKYG 249
A G+++ V + I+ N+NG +HLA + G++ + + L+ + + + K G
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKG 97
Query: 250 YQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDIS 429
+H+A G +++K+L+ + +I+A ++ G+ P+++A + HID+VK L++N + S
Sbjct: 98 NTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQS 157
Query: 430 TSNKYGYQPIHLACENGHIDIMKILIDN 513
T+ + G+ P+ +A + GH + IL++N
Sbjct: 158 TATEDGFTPLAVALQQGHNQAVAILLEN 185
Score = 92.8 bits (229), Expect = 6e-19
Identities = 44/207 (21%), Positives = 102/207 (49%), Gaps = 37/207 (17%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K+L+ +I+A ++NG+ P+++A + HI++VK L++ S ++G+ P+ +A +
Sbjct: 114 KVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQ 173
Query: 181 GYIDIAKILID-------------------------------------KKCDISTFNKYG 249
G+ IL++ K ++ + G
Sbjct: 174 GHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESG 233
Query: 250 YQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDIS 429
+ P+H+A G++++ +L+++ + + + G P+H+A + G+ ++VK+L+D I
Sbjct: 234 FTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQID 293
Query: 430 TSNKYGYQPIHLACENGHIDIMKILID 510
+ G P+H A +GH ++++L++
Sbjct: 294 AKTRDGLTPLHCAARSGHDQVVELLLE 320
Score = 88.2 bits (217), Expect = 1e-17
Identities = 45/212 (21%), Positives = 103/212 (48%), Gaps = 37/212 (17%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGY 186
L+ + + + G +H+A G E+VK+L+ + I+A ++NG+ P+++A + +
Sbjct: 83 LLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENH 142
Query: 187 IDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILID------------------ 312
ID+ K L++ + ST + G+ P+ +A + GH + IL++
Sbjct: 143 IDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARK 202
Query: 313 -------------------KKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDISTS 435
K ++ + + G+ P+H+A G++++ +L++ + +
Sbjct: 203 DDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFT 262
Query: 436 NKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
+ G P+H+A + G+ +++K+L+D I+A
Sbjct: 263 ARNGITPLHVASKRGNTNMVKLLLDRGGQIDA 294
Score = 69.7 bits (169), Expect = 5e-12
Identities = 35/134 (26%), Positives = 65/134 (48%)
Frame = +1
Query: 4 ILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENG 183
+L+D +I ++G +HLA + + + IL A+ K GY P+ +AC G
Sbjct: 680 LLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYG 739
Query: 184 YIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH 363
+ + L+ + +++ K GY P+H A + GH I+ +L+ +A+ G +
Sbjct: 740 NVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALA 799
Query: 364 LACENGHIDIVKIL 405
+A G+I +V L
Sbjct: 800 IAKRLGYISVVDTL 813
Score = 53.1 bits (126), Expect = 5e-07
Identities = 24/91 (26%), Positives = 48/91 (52%)
Frame = +1
Query: 268 ACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDISTSNKYG 447
A + G++D + + DI+ N+ G +HLA + GH+ +V+ L+ + ++ K G
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKG 97
Query: 448 YQPIHLACENGHIDIMKILIDNKCGINAHDE 540
+H+A G +++K+L+ INA +
Sbjct: 98 NTALHIASLAGQAEVVKVLVKEGANINAQSQ 128
>sp|P53355|DAPK1_HUMAN Death-associated protein kinase 1 (DAP kinase 1)
Length = 1432
Score = 111 bits (278), Expect = 1e-24
Identities = 48/149 (32%), Positives = 89/149 (59%)
Frame = +1
Query: 58 PIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILIDKKCDISTF 237
P+H A +G+ + K L + C ++ N+ G P+ A GY DI + L + D++
Sbjct: 483 PLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNAC 542
Query: 238 NKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNK 417
+K G+ +HLA + ++++K L+ + C + +++G P+H+AC++G++ IV L +
Sbjct: 543 DKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEAN 602
Query: 418 CDISTSNKYGYQPIHLACENGHIDIMKIL 504
C++ SNKYG P+HLA NG +D+++ L
Sbjct: 603 CNLDISNKYGRTPLHLAANNGILDVVRYL 631
Score = 105 bits (261), Expect = 1e-22
Identities = 49/178 (27%), Positives = 99/178 (55%), Gaps = 2/178 (1%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEI--VKILIDKKCYISAYNKNGYQPIHLAC 174
K L +NKC + +++G +H+A GH ++ V++L + +K P+H A
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQVQVLCSFGSNPNIQDKEEETPLHCAA 488
Query: 175 ENGYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQ 354
+GY +AK L + C+++ N+ G P+ A G+ DI++ L + D++A +K G+
Sbjct: 489 WHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHI 548
Query: 355 PIHLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
+HLA ++++K L+ C + +++G P+H+AC++G++ I+ L + C ++
Sbjct: 549 ALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLD 606
Score = 97.4 bits (241), Expect = 2e-20
Identities = 44/135 (32%), Positives = 81/135 (60%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K L + C+++ N G P+ A G+ +IV+ L + ++A +K+G+ +HLA
Sbjct: 497 KALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRR 556
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
+++ K L+ + C + +++G P+H+ACK+G++ I+ L + C++ SNKYG P+
Sbjct: 557 CQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPL 616
Query: 361 HLACENGHIDIVKIL 405
HLA NG +D+V+ L
Sbjct: 617 HLAANNGILDVVRYL 631
Score = 94.0 bits (232), Expect = 3e-19
Identities = 47/174 (27%), Positives = 95/174 (54%), Gaps = 2/174 (1%)
Frame = +1
Query: 25 DISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKI 204
D++ N++G P+ +A G+I+I+++LI + I +K G ++ A +G++D K
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKF 430
Query: 205 LIDKKCDISTFNKYGYQPIHLACKNGHIDI--MKILIDKKCDISASNKYGYQPIHLACEN 378
L + KC + +K G +H+A + GH D+ +++L + + +K P+H A +
Sbjct: 431 LSENKCPLDVKDKSGEMALHVAARYGHADVAQVQVLCSFGSNPNIQDKEEETPLHCAAWH 490
Query: 379 GHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
G+ + K L + C+++ N+ G P+ A G+ DI++ L ++ +NA D+
Sbjct: 491 GYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDK 544
Score = 92.4 bits (228), Expect = 8e-19
Identities = 46/181 (25%), Positives = 95/181 (52%), Gaps = 2/181 (1%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++LI I ++ G ++ A +GH++ +K L + KC + +K+G +H+A
Sbjct: 396 QLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARY 455
Query: 181 GYIDIAKI--LIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQ 354
G+ D+A++ L + + +K P+H A +G+ + K L + C+++ N+ G
Sbjct: 456 GHADVAQVQVLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGET 515
Query: 355 PIHLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAH 534
P+ A G+ DIV+ L ++ D++ +K G+ +HLA ++++K L+ C ++
Sbjct: 516 PLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQ 575
Query: 535 D 537
D
Sbjct: 576 D 576
Score = 83.2 bits (204), Expect = 5e-16
Identities = 38/133 (28%), Positives = 73/133 (54%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGY 186
L ++ D++A +++G+ +HLA +E++K L+ + C++ +++G P+H+AC++G
Sbjct: 532 LAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGN 591
Query: 187 IDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHL 366
+ I L + C++ NKYG P+HLA NG +D+++ L + A G L
Sbjct: 592 MPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDL 651
Query: 367 ACENGHIDIVKIL 405
A H + +L
Sbjct: 652 ARSEQHEHVAGLL 664
Score = 58.5 bits (140), Expect = 1e-08
Identities = 29/102 (28%), Positives = 48/102 (47%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K L+ C + + +G P+H+AC++G++ IV L + C + NK G P+HLA N
Sbjct: 563 KTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANN 622
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKIL 306
G +D+ + L + G LA H + +L
Sbjct: 623 GILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLL 664
>sp|P57078|RIPK4_HUMAN Serine/threonine-protein kinase RIPK4 (Receptor-interacting
serine/threonine-protein kinase 4) (Ankyrin repeat domain
protein 3) (PKC-delta-interacting protein kinase)
Length = 832
Score = 110 bits (274), Expect = 4e-24
Identities = 52/170 (30%), Positives = 93/170 (54%), Gaps = 1/170 (0%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKK-CYISAYNKNGYQPIHLACE 177
+IL+ D+S ++ + P+H A GH+ IVK+L + ++A +G P+HLA +
Sbjct: 602 RILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQ 661
Query: 178 NGYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQP 357
G+ +A+ILID D++ + P+H+A + GH ++L+ + A GY
Sbjct: 662 RGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTA 721
Query: 358 IHLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILI 507
+HLA NGH+ VK+L++ K D+ +HLA +GH ++++ L+
Sbjct: 722 LHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV 771
Score = 108 bits (270), Expect = 1e-23
Identities = 51/178 (28%), Positives = 94/178 (52%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L++ ++ + G P+H+AC++G IV+IL+ + +S K+ + P+H A
Sbjct: 569 RLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQ 628
Query: 181 GYIDIAKILIDKK-CDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQP 357
G++ I K+L + ++ G P+HLA + GH + +ILID D++ + P
Sbjct: 629 GHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTP 688
Query: 358 IHLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINA 531
+H+A E GH ++L+ GY +HLA NGH+ +K+L++ K + A
Sbjct: 689 LHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLA 746
Score = 103 bits (257), Expect = 3e-22
Identities = 52/177 (29%), Positives = 98/177 (55%), Gaps = 1/177 (0%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K L+ N + + N G P+H+A E +V++L+ +K ++A +++ + +H A +N
Sbjct: 503 KWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQN 562
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPI 360
G ++L++K ++ + G P+H+AC++G +I++IL+ + D+S K + P+
Sbjct: 563 GDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPL 622
Query: 361 HLACENGHIDIVKILIDNK-CDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGIN 528
H A GH+ IVK+L ++ G P+HLA + GH + +ILID +N
Sbjct: 623 HYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVN 679
Score = 92.0 bits (227), Expect = 1e-18
Identities = 45/160 (28%), Positives = 86/160 (53%)
Frame = +1
Query: 25 DISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKI 204
D+ ++G +HLA E G E K L+ + N+ G P+H+A E + ++
Sbjct: 478 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 537
Query: 205 LIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGH 384
L+ +K ++ ++ + +H A +NG ++L++K ++ + G P+H+AC++G
Sbjct: 538 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 597
Query: 385 IDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKIL 504
+IV+IL+ D+S K + P+H A GH+ I+K+L
Sbjct: 598 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 637
Score = 67.0 bits (162), Expect = 4e-11
Identities = 31/121 (25%), Positives = 69/121 (57%)
Frame = +1
Query: 145 NGYQPIHLACENGYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCD 324
+G +HLA E G + AK L+ + + N+ G P+H+A + ++++L+ +K
Sbjct: 485 SGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKIS 544
Query: 325 ISASNKYGYQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKIL 504
++A ++ + +H A +NG ++L++ ++ + G P+H+AC++G +I++IL
Sbjct: 545 VNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRIL 604
Query: 505 I 507
+
Sbjct: 605 L 605
Score = 50.1 bits (118), Expect = 4e-06
Identities = 28/115 (24%), Positives = 58/115 (50%)
Frame = +1
Query: 193 IAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLAC 372
+ KIL + D++ + G +HLA + G + K L+ + + SN+ G P+H+A
Sbjct: 470 LMKILQPQDVDLALDS--GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAV 527
Query: 373 ENGHIDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHD 537
E +V++L+ K ++ ++ + +H A +NG ++L++ +N D
Sbjct: 528 ERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVD 582
Score = 48.1 bits (113), Expect = 2e-05
Identities = 27/83 (32%), Positives = 46/83 (55%)
Frame = +1
Query: 292 IMKILIDKKCDISASNKYGYQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLAC 471
+MKIL + D++ + G +HLA E G + K L+ N + + SN+ G P+H+A
Sbjct: 470 LMKILQPQDVDLALDS--GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAV 527
Query: 472 ENGHIDIMKILIDNKCGINAHDE 540
E ++++L+ K +NA DE
Sbjct: 528 ERRVRGVVELLLARKISVNAKDE 550
>sp|Q80YE7|DAPK1_MOUSE Death-associated protein kinase 1 (DAP kinase 1)
Length = 1442
Score = 105 bits (261), Expect = 1e-22
Identities = 57/201 (28%), Positives = 98/201 (48%), Gaps = 33/201 (16%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K L +NKC + +++G +H+A GH ++V++L +K P+H A +
Sbjct: 429 KFLNENKCPLDVKDKSGETALHVAARYGHADVVQLLCSFGSNPDFQDKEEETPLHCAAWH 488
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNK------ 342
GY +AK L + C+++ N+ G P+ A G+ DI++ L + D++AS+K
Sbjct: 489 GYYSVAKALCEVGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNASDKDGHIAL 548
Query: 343 ---------------------------YGYQPIHLACENGHIDIVKILIDNKCDISTSNK 441
+G P+H+AC++G IV L + C++ SNK
Sbjct: 549 HLAVRRCQMEVIKTLLGHGSFVDFQDRHGNTPLHVACKDGSAPIVVALCEASCNLDISNK 608
Query: 442 YGYQPIHLACENGHIDIMKIL 504
YG P+HLA NG +D+++ L
Sbjct: 609 YGRTPLHLAANNGILDVVRYL 629
Score = 96.3 bits (238), Expect = 5e-20
Identities = 47/172 (27%), Positives = 94/172 (54%)
Frame = +1
Query: 25 DISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKI 204
D++ N++G P+ +A G+I+++++LI + I +K G I+ A +G++D K
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQMLQLLIKRGSRIDVQDKGGSNAIYWASRHGHVDTLKF 430
Query: 205 LIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHLACENGH 384
L + KC + +K G +H+A + GH D++++L + +K P+H A +G+
Sbjct: 431 LNENKCPLDVKDKSGETALHVAARYGHADVVQLLCSFGSNPDFQDKEEETPLHCAAWHGY 490
Query: 385 IDIVKILIDNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGINAHDE 540
+ K L + C+++ N+ G P+ A G+ DI++ L ++ +NA D+
Sbjct: 491 YSVAKALCEVGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNASDK 542
Score = 77.8 bits (190), Expect = 2e-14
Identities = 37/133 (27%), Positives = 71/133 (53%)
Frame = +1
Query: 7 LIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGY 186
L ++ D++A +++G+ +HLA +E++K L+ ++ +++G P+H+AC++G
Sbjct: 530 LAEHGADLNASDKDGHIALHLAVRRCQMEVIKTLLGHGSFVDFQDRHGNTPLHVACKDGS 589
Query: 187 IDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIHL 366
I L + C++ NKYG P+HLA NG +D+++ L ++ A G L
Sbjct: 590 APIVVALCEASCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGANVEALTSDGKTAEDL 649
Query: 367 ACENGHIDIVKIL 405
A H + +L
Sbjct: 650 AKAEQHEHVAGLL 662
Score = 53.5 bits (127), Expect = 4e-07
Identities = 28/102 (27%), Positives = 47/102 (46%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
K L+ + + + +G P+H+AC++G IV L + C + NK G P+HLA N
Sbjct: 561 KTLLGHGSFVDFQDRHGNTPLHVACKDGSAPIVVALCEASCNLDISNKYGRTPLHLAANN 620
Query: 181 GYIDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKIL 306
G +D+ + L ++ G LA H + +L
Sbjct: 621 GILDVVRYLCLMGANVEALTSDGKTAEDLAKAEQHEHVAGLL 662
>sp|Q8R516|MIB2_MOUSE Ubiquitin ligase protein MIB2 (Mind bomb homolog 2) (Mind bomb-2)
(Skeletrophin) (Dystrophin-like protein) (Dyslike)
Length = 973
Score = 100 bits (249), Expect = 3e-21
Identities = 52/185 (28%), Positives = 99/185 (53%), Gaps = 5/185 (2%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACEN 180
++L+ C + A N +H+A + G +E+VKIL ++ C ++ + + P+H A
Sbjct: 531 RVLLSAGCAVDARNGTRSTALHVAVQRGFLEVVKILCERGCDVNLPDAHADTPLHSAISA 590
Query: 181 GY--IDIAKILIDKK-CDISTFNKYGYQPIHLACKNGHI-DIMKILIDKKCDISASNKYG 348
G I ++L + D++ N G+ +H A GH+ + KIL + + A + G
Sbjct: 591 GAGASSIVEVLTEVPGIDVTATNSQGFTLLHHASLKGHVLAVRKILARARQLVDAKKEDG 650
Query: 349 YQPIHLACENGHIDIVKILI-DNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGI 525
+ +HLA N H ++ ++LI + +CD++ N+ P+HLA + H+ ++ +L+D C +
Sbjct: 651 FTALHLAALNNHREVAQVLIREGRCDVNVRNRKLQSPLHLAVQQAHLGLVPLLVDAGCSV 710
Query: 526 NAHDE 540
N DE
Sbjct: 711 NTEDE 715
Score = 80.5 bits (197), Expect = 3e-15
Identities = 45/163 (27%), Positives = 88/163 (53%), Gaps = 5/163 (3%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGH--IEIVKILIDKKCY-ISAYNKNGYQPIHLA 171
KIL + CD++ + + P+H A G IV++L + ++A N G+ +H A
Sbjct: 564 KILCERGCDVNLPDAHADTPLHSAISAGAGASSIVEVLTEVPGIDVTATNSQGFTLLHHA 623
Query: 172 CENGYI-DIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILI-DKKCDISASNKY 345
G++ + KIL + + + G+ +HLA N H ++ ++LI + +CD++ N+
Sbjct: 624 SLKGHVLAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQVLIREGRCDVNVRNRK 683
Query: 346 GYQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACE 474
P+HLA + H+ +V +L+D C ++T ++ G +H+A +
Sbjct: 684 LQSPLHLAVQQAHLGLVPLLVDAGCSVNTEDEEGDTALHVALQ 726
Score = 64.3 bits (155), Expect = 2e-10
Identities = 37/168 (22%), Positives = 82/168 (48%), Gaps = 4/168 (2%)
Frame = +1
Query: 49 GYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILIDKKCDI 228
G + +A G +E+V++L+ + + + G +H + ++L+ C +
Sbjct: 481 GRTALQVAAYLGQVELVRLLLQARASMDLPDDEGNTVLHYTAMGNQPEATRVLLSAGCAV 540
Query: 229 STFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH--LACENGHIDIVKI 402
N +H+A + G ++++KIL ++ CD++ + + P+H ++ G IV++
Sbjct: 541 DARNGTRSTALHVAVQRGFLEVVKILCERGCDVNLPDAHADTPLHSAISAGAGASSIVEV 600
Query: 403 LID-NKCDISTSNKYGYQPIHLACENGHI-DIMKILIDNKCGINAHDE 540
L + D++ +N G+ +H A GH+ + KIL + ++A E
Sbjct: 601 LTEVPGIDVTATNSQGFTLLHHASLKGHVLAVRKILARARQLVDAKKE 648
>sp|Q96AX9|MIB2_HUMAN Ubiquitin ligase protein MIB2 (Mind bomb homolog 2) (Zinc finger ZZ
type with ankyrin repeat domain protein 1) (Skeletrophin)
(Novelzin) (Novel zinc finger protein) (Putative
NF-kappa-B-activating protein 002N)
Length = 1013
Score = 100 bits (248), Expect = 4e-21
Identities = 52/185 (28%), Positives = 98/185 (52%), Gaps = 5/185 (2%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACE- 177
++L+ C A N +H+A + G +E+V+ L ++ C ++ + + P+H A
Sbjct: 573 RVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISA 632
Query: 178 -NGYIDIAKILID-KKCDISTFNKYGYQPIHLACKNGH-IDIMKILIDKKCDISASNKYG 348
G I ++L + D++ N G+ +H A GH + + KIL + + A + G
Sbjct: 633 GTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDG 692
Query: 349 YQPIHLACENGHIDIVKILI-DNKCDISTSNKYGYQPIHLACENGHIDIMKILIDNKCGI 525
+ +HLA N H ++ +ILI + +CD++ N+ P+HLA + H+ ++ +L+D C +
Sbjct: 693 FTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSV 752
Query: 526 NAHDE 540
NA DE
Sbjct: 753 NAEDE 757
Score = 76.6 bits (187), Expect = 4e-14
Identities = 43/163 (26%), Positives = 86/163 (52%), Gaps = 5/163 (3%)
Frame = +1
Query: 1 KILIDNKCDISAYNENGYQPIHLACE--NGHIEIVKILID-KKCYISAYNKNGYQPIHLA 171
+ L + CD++ + + P+H A G IV++L + ++A N G+ +H A
Sbjct: 606 RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHA 665
Query: 172 CENGY-IDIAKILIDKKCDISTFNKYGYQPIHLACKNGHIDIMKILI-DKKCDISASNKY 345
G+ + + KIL + + + G+ +HLA N H ++ +ILI + +CD++ N+
Sbjct: 666 SLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRK 725
Query: 346 GYQPIHLACENGHIDIVKILIDNKCDISTSNKYGYQPIHLACE 474
P+HLA + H+ +V +L+D C ++ ++ G +H+A +
Sbjct: 726 LQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQ 768
Score = 63.9 bits (154), Expect = 3e-10
Identities = 35/168 (20%), Positives = 81/168 (48%), Gaps = 4/168 (2%)
Frame = +1
Query: 49 GYQPIHLACENGHIEIVKILIDKKCYISAYNKNGYQPIHLACENGYIDIAKILIDKKCDI 228
G + +A G +E++++L+ + + + G +H A + ++L+ C
Sbjct: 523 GRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA 582
Query: 229 STFNKYGYQPIHLACKNGHIDIMKILIDKKCDISASNKYGYQPIH--LACENGHIDIVKI 402
N +H+A + G +++++ L ++ CD++ + + P+H ++ G IV++
Sbjct: 583 DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEV 642
Query: 403 LID-NKCDISTSNKYGYQPIHLACENGH-IDIMKILIDNKCGINAHDE 540
L + D++ +N G+ +H A GH + + KIL + ++A E
Sbjct: 643 LTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKE 690
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,685,449
Number of Sequences: 369166
Number of extensions: 1371993
Number of successful extensions: 6794
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2854
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5169
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4699949280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)