Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_P11-2
(455 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P02977|M5_STRP5 M protein, serotype 5 precursor 43 3e-04
sp|P38853|KEL1_YEAST Kelch repeats protein 1 42 5e-04
sp|Q12527|ATG11_YEAST Autophagy-related protein 11 (Cytopla... 41 0.001
sp|Q6BSY1|MAD1_DEBHA Spindle assembly checkpoint component ... 41 0.001
sp|Q86RN8|MYSP_BOOMI Paramyosin 41 0.001
sp|Q28641|MYH4_RABIT Myosin-4 (Myosin heavy chain, skeletal... 41 0.001
sp|Q9UTJ3|MEU1_SCHPO Meiotic expression up-regulated protei... 41 0.001
sp|P47394|Y148_MYCGE Hypothetical protein MG148 41 0.001
sp|P13535|MYH8_HUMAN Myosin-8 (Myosin heavy chain, skeletal... 40 0.002
sp|Q5SX39|MYH4_MOUSE Myosin-4 (Myosin heavy chain, skeletal... 40 0.002
>sp|P02977|M5_STRP5 M protein, serotype 5 precursor
Length = 492
Score = 43.1 bits (100), Expect = 3e-04
Identities = 35/146 (23%), Positives = 63/146 (43%)
Frame = +3
Query: 18 FKLQNDVIRTECENLFSENERLKSQIETYKASQASSNVTNKVEDIVDSPVHQDHQYKIRY 197
++L+N ++T+ E L +ENE LK++ E K K +H+ +
Sbjct: 62 YELENHDLKTKNEGLKTENEGLKTENEGLKTENEGLKTEKK-----------EHEAENDK 110
Query: 198 LQHEVTKLLDEKTNIENENQTLINDIKTLRESENELVNRINSLLNEKTKLTNKHAMVEKE 377
L+ + L +K +E E Q + +TL+ +L +N E L NK ++
Sbjct: 111 LKQQRDTLSTQKETLEREVQNTQYNNETLKIKNGDLTKELNKTRQE---LANKQQESKEN 167
Query: 378 IDFLNLNHSKEIEDQISNHNAQIETL 455
LN K ++D+I+ ET+
Sbjct: 168 EKALNELLEKTVKDKIAKEQENKETI 193
>sp|P38853|KEL1_YEAST Kelch repeats protein 1
Length = 1164
Score = 42.4 bits (98), Expect = 5e-04
Identities = 35/154 (22%), Positives = 66/154 (42%), Gaps = 10/154 (6%)
Frame = +3
Query: 6 IEGNFKLQNDVIRTECENLFSENERLKSQIETYK----------ASQASSNVTNKVEDIV 155
+E N+K + + ++ E ENL ENERLK++ + + +SQ S +++ E+
Sbjct: 886 LEPNYKEKLEELQIEHENLSRENERLKNESKQHNEDIINNVANYSSQLGSLISHWKENRA 945
Query: 156 DSPVHQDHQYKIRYLQHEVTKLLDEKTNIENENQTLINDIKTLRESENELVNRINSLLNE 335
+S + I K + E ++ + ++ N+L NR++ LL
Sbjct: 946 NSSFLESSSSLISVSDENGEKTVGEPYGDQSRHHRVV---------INKLTNRLDDLLER 996
Query: 336 KTKLTNKHAMVEKEIDFLNLNHSKEIEDQISNHN 437
+LT + E L + HS +D + N
Sbjct: 997 SQELTISKEKLSSEYHALKMEHSSLSQDVLVKEN 1030
>sp|Q12527|ATG11_YEAST Autophagy-related protein 11 (Cytoplasm to vacuole targeting protein
9)
Length = 1178
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/123 (26%), Positives = 60/123 (48%)
Frame = +3
Query: 87 SQIETYKASQASSNVTNKVEDIVDSPVHQDHQYKIRYLQHEVTKLLDEKTNIENENQTLI 266
S++ SQA+++ ++E VD +HQ ++ L+ E + K+ +E I
Sbjct: 688 SEVNIDSVSQANNHQIQELESNVDDLLHQ-----LQLLKEENNR----KSMQISEMGKKI 738
Query: 267 NDIKTLRESENELVNRINSLLNEKTKLTNKHAMVEKEIDFLNLNHSKEIEDQISNHNAQI 446
+D++ + + E + +N E +LTN+ EI LN + K++ D IS N +I
Sbjct: 739 SDLEVEKTAYRETLTNLN---QELARLTNEEQSHRTEIFTLNASFKKQLNDIISQDNEKI 795
Query: 447 ETL 455
E L
Sbjct: 796 EKL 798
>sp|Q6BSY1|MAD1_DEBHA Spindle assembly checkpoint component MAD1 (Mitotic arrest
deficient protein 1)
Length = 669
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/134 (20%), Positives = 62/134 (46%), Gaps = 6/134 (4%)
Frame = +3
Query: 57 NLFSENERLKSQIETYKASQASSNVTNKVED------IVDSPVHQDHQYKIRYLQHEVTK 218
NL + +++I T + S + + V+ I+D+ + D + ++ L+ E K
Sbjct: 395 NLEKLVDEYRTEINTLQKQMLSQEIQSNVQSGSKRPRIIDNGIQNDFKSQVSVLEKENLK 454
Query: 219 LLDEKTNIENENQTLINDIKTLRESENELVNRINSLLNEKTKLTNKHAMVEKEIDFLNLN 398
LL N+E N+TL ++ L +N+ ++ L + + + ++ +D L+
Sbjct: 455 LLSTIKNLEYNNKTLGEKLQNLESLDNK-KKELHILQLKSNPASQDQLIKQQTLDLLSKE 513
Query: 399 HSKEIEDQISNHNA 440
+ + IE + N +A
Sbjct: 514 NQEMIETFVKNKSA 527
>sp|Q86RN8|MYSP_BOOMI Paramyosin
Length = 873
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/137 (21%), Positives = 63/137 (45%), Gaps = 24/137 (17%)
Frame = +3
Query: 18 FKLQNDVIRTECENLFSENERLKSQIETY-----KASQASSNVTNKVEDI------VDSP 164
++ Q + + T C NL + RL+S++E KA+ + N+ +V + + S
Sbjct: 322 YEEQLEALLTRCSNLEKQKSRLQSEVEVLIMDLEKATAHAQNLEKRVAQLEKLNIDLKSK 381
Query: 165 VHQ-------------DHQYKIRYLQHEVTKLLDEKTNIENENQTLINDIKTLRESENEL 305
V + +I+ LQHE K+ +++ ++ EN+ L++D+ + +
Sbjct: 382 VEELTILLEQSQRELRQKVAEIQKLQHEYEKMREQRDALQRENKKLVDDLSEAKSQLADA 441
Query: 306 VNRINSLLNEKTKLTNK 356
+ R++ E +L N+
Sbjct: 442 IRRLHEYELEIKRLENE 458
>sp|Q28641|MYH4_RABIT Myosin-4 (Myosin heavy chain, skeletal muscle, juvenile)
Length = 1938
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/139 (23%), Positives = 65/139 (46%), Gaps = 1/139 (0%)
Frame = +3
Query: 39 IRTECENLFSENERLKSQIETYKASQASSNVTNKVEDIVDSPVHQDHQYKIRYLQHEVTK 218
+ TE + + E Q+ET K + + N+ ++ D+ + + HE+ K
Sbjct: 1480 LSTEVFKVKNAYEESLDQLETLK--RENKNLQQEISDLTEQIAEGGKRI------HELEK 1531
Query: 219 LLDEKTNIENENQTLINDIKTLRESENELVNRINSLLNE-KTKLTNKHAMVEKEIDFLNL 395
+ + ++E Q + + + E E + RI LN+ K+++ K A ++EID L
Sbjct: 1532 VKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKR 1591
Query: 396 NHSKEIEDQISNHNAQIET 452
NH + +E S +A+I +
Sbjct: 1592 NHIRVVESMQSTLDAEIRS 1610
Score = 33.1 bits (74), Expect = 0.30
Identities = 34/145 (23%), Positives = 62/145 (42%)
Frame = +3
Query: 21 KLQNDVIRTECENLFSENERLKSQIETYKASQASSNVTNKVEDIVDSPVHQDHQYKIRYL 200
KL+ D+ + + EN++ + + K SN+ +K+ED + + Q KI+ L
Sbjct: 1057 KLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIED--EQALAMQLQKKIKEL 1114
Query: 201 QHEVTKLLDEKTNIENENQTLINDIKTLRESENELVNRINSLLNEKTKLTNKHAMVEKEI 380
Q + +L +E IE E + K + EL I+ L E T+ + K+
Sbjct: 1115 QARIEELEEE---IEAERASRAKAEKQRSDLSREL-EEISERLEEAGGATSAQIEMNKKR 1170
Query: 381 DFLNLNHSKEIEDQISNHNAQIETL 455
+ +++E+ H A TL
Sbjct: 1171 EAEFQKMRRDLEEATLQHEATAATL 1195
>sp|Q9UTJ3|MEU1_SCHPO Meiotic expression up-regulated protein 1/2
Length = 776
Score = 40.8 bits (94), Expect = 0.001
Identities = 29/154 (18%), Positives = 72/154 (46%), Gaps = 21/154 (13%)
Frame = +3
Query: 21 KLQNDVIRTECENLFSENERLKSQIETYKASQASSNVTNKVEDIVDSPVHQDHQYKIRYL 200
+LQN+ + + E + EN+RL + +++ + S ++ D+ +S +DH
Sbjct: 184 QLQNENFKDDYEKIKEENKRLYKERKSFLSKIEKSAC--EIHDLKESDSFKDH------- 234
Query: 201 QHEVTKLLDEKT---------------------NIENENQTLINDIKTLRESENELVNRI 317
E+ +L +E+T +E+EN+ LIN++ +R +L +
Sbjct: 235 --EILRLKEERTAAMQAIDDISGTIETIKSDCYKVESENKGLINEVMDMRNFVQQLEQEL 292
Query: 318 NSLLNEKTKLTNKHAMVEKEIDFLNLNHSKEIED 419
+ ++ +++ N +++ + LN + ++ +E+
Sbjct: 293 YAFEDDYSRIQNDEELLKVGMIHLNKSENRTVEE 326
Score = 28.1 bits (61), Expect = 9.6
Identities = 21/97 (21%), Positives = 43/97 (44%), Gaps = 12/97 (12%)
Frame = +3
Query: 63 FSENERLKSQIETYKASQASSNVTNKVEDIVDSPVHQDHQYK------------IRYLQH 206
F ++E L+ + E A QA +++ +E I + + K ++ L+
Sbjct: 231 FKDHEILRLKEERTAAMQAIDDISGTIETIKSDCYKVESENKGLINEVMDMRNFVQQLEQ 290
Query: 207 EVTKLLDEKTNIENENQTLINDIKTLRESENELVNRI 317
E+ D+ + I+N+ + L + L +SEN V +
Sbjct: 291 ELYAFEDDYSRIQNDEELLKVGMIHLNKSENRTVEEM 327
>sp|P47394|Y148_MYCGE Hypothetical protein MG148
Length = 409
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/151 (26%), Positives = 70/151 (46%), Gaps = 4/151 (2%)
Frame = +3
Query: 15 NFKLQNDVIRTECENLFSENERLKSQIETYKASQASSNVTNKVEDIVDSPVHQDHQYKIR 194
N L N V +T N + N++L + E S+ N+ ++ I+
Sbjct: 27 NLDLINQVDQTNILNTITTNQKLAWEKEL------SAQFINQQNEL------------IK 68
Query: 195 YLQHEVTKLLDEKTNIENENQTLINDIKTLRESENELVNRINSLLNE--KTKLTNKHAMV 368
+ E+ KL KT + ++ Q L+ +KT E +N+ +I + +NE K KLTNK +
Sbjct: 69 NFEIEIIKL---KTMLNDKEQALL--LKTKLELQNQFQKQIENYINEINKLKLTNKELEI 123
Query: 369 --EKEIDFLNLNHSKEIEDQISNHNAQIETL 455
+K+++ E E++I+ N IE L
Sbjct: 124 TNQKQLESSLKLQRNEFEEKINQQNLTIEKL 154
>sp|P13535|MYH8_HUMAN Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)
(MyHC-perinatal)
Length = 1937
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/139 (23%), Positives = 65/139 (46%), Gaps = 1/139 (0%)
Frame = +3
Query: 39 IRTECENLFSENERLKSQIETYKASQASSNVTNKVEDIVDSPVHQDHQYKIRYLQHEVTK 218
+ TE + + E Q+ET + + + N+ ++ D+ + Q HE+ K
Sbjct: 1480 LSTELFKVKNVYEESLDQLETLR--RENKNLQQEISDLTEQIAEGGKQI------HELEK 1531
Query: 219 LLDEKTNIENENQTLINDIKTLRESENELVNRINSLLNE-KTKLTNKHAMVEKEIDFLNL 395
+ + + E Q + + + E E + RI LN+ K+++ K A ++EID L
Sbjct: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKR 1591
Query: 396 NHSKEIEDQISNHNAQIET 452
NH++ +E S +A+I +
Sbjct: 1592 NHTRVVETMQSTLDAEIRS 1610
Score = 34.3 bits (77), Expect = 0.13
Identities = 37/147 (25%), Positives = 64/147 (43%), Gaps = 2/147 (1%)
Frame = +3
Query: 21 KLQNDVIRTECENLFSENERLKSQIETYKASQASSNVTNKVEDIVDSPVHQDHQYKIRYL 200
KL+ D+ + + EN++ + + K SN+ +K+ED + V Q KI+ L
Sbjct: 1057 KLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIED--EQAVEIQLQKKIKEL 1114
Query: 201 QHEVTKLLDEKTNIENENQTLINDIKTLRESENELVNRINSLLNEKTKLTNKHAMVEK-- 374
Q + +L +E IE E + K + EL I+ L E T+ + K
Sbjct: 1115 QARIEELGEE---IEAERASRAKAEKQRSDLSREL-EEISERLEEAGGATSAQVELNKKR 1170
Query: 375 EIDFLNLNHSKEIEDQISNHNAQIETL 455
E +F L +++E+ H A + L
Sbjct: 1171 EAEFQKLR--RDLEEATLQHEAMVAAL 1195
>sp|Q5SX39|MYH4_MOUSE Myosin-4 (Myosin heavy chain, skeletal muscle, fetal)
Length = 1939
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 1/139 (0%)
Frame = +3
Query: 39 IRTECENLFSENERLKSQIETYKASQASSNVTNKVEDIVDSPVHQDHQYKIRYLQHEVTK 218
+ TE + + E Q+ET K + + N+ ++ D+ + HE+ K
Sbjct: 1481 LSTELFKVKNAYEESLDQLETLK--RENKNLQQEISDLTEQIAEGGKHI------HELEK 1532
Query: 219 LLDEKTNIENENQTLINDIKTLRESENELVNRINSLLNE-KTKLTNKHAMVEKEIDFLNL 395
+ + ++E Q + + + E E + RI LN+ K+++ K A ++EID L
Sbjct: 1533 IKKQIDQEKSELQASLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKR 1592
Query: 396 NHSKEIEDQISNHNAQIET 452
NH + +E S +A+I +
Sbjct: 1593 NHLRVVESMQSTLDAEIRS 1611
Score = 32.7 bits (73), Expect = 0.39
Identities = 30/159 (18%), Positives = 66/159 (41%), Gaps = 14/159 (8%)
Frame = +3
Query: 21 KLQNDVIRTECENLFSENERLKSQIETYKASQASSNVTNKVEDIVDSPVHQDHQYKIRYL 200
KL+ D+ + + EN++ + + K SN+ +K+ED + + Q KI+ L
Sbjct: 1058 KLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIED--EQALGMQLQKKIKEL 1115
Query: 201 QHEVTKLLDE-------KTNIENENQTLINDIKTLRESENELVNRINSLLNEKTKLTNKH 359
Q + +L +E + E + L +++ + E E ++ + K +
Sbjct: 1116 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEF 1175
Query: 360 AMVEKEIDFLNLNHS-------KEIEDQISNHNAQIETL 455
+ ++++ L H K+ D ++ QI+ L
Sbjct: 1176 QKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1214
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,059,367
Number of Sequences: 369166
Number of extensions: 505008
Number of successful extensions: 3551
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3216
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3513
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2484837250
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)