Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_O24
(575 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P18910|ANPRA_RAT Atrial natriuretic peptide receptor A p... 171 9e-43
sp|P18293|ANPRA_MOUSE Atrial natriuretic peptide receptor A... 170 2e-42
sp|P16066|ANPRA_HUMAN Atrial natriuretic peptide receptor A... 168 8e-42
sp|P46197|ANPRB_BOVIN Atrial natriuretic peptide receptor B... 167 2e-41
sp|P16067|ANPRB_RAT Atrial natriuretic peptide receptor B p... 167 2e-41
sp|P20594|ANPRB_HUMAN Atrial natriuretic peptide receptor B... 167 2e-41
sp|P55202|ANPRB_ANGJA Atrial natriuretic peptide receptor B... 166 4e-41
sp|Q6VVW5|ANPRB_MOUSE Atrial natriuretic peptide receptor B... 164 1e-40
sp|Q6TL19|GUC2G_MOUSE Guanylate cyclase 2G precursor (Guany... 146 3e-35
sp|P55205|GUC2G_RAT Guanylate cyclase 2G precursor (Guanyly... 146 4e-35
>sp|P18910|ANPRA_RAT Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA)
(GC-A) (Guanylate cyclase) (NPR-A) (Atrial natriuretic
peptide A-type receptor)
Length = 1057
Score = 171 bits (434), Expect = 9e-43
Identities = 85/125 (68%), Positives = 96/125 (76%)
Frame = +3
Query: 3 VSGLPNINGKLHAREIARMCLQFLSAIFRFVIPHRPNKQLELRIGVHSGPVCAGVVGHKM 182
VSGLP NG+LHARE+ARM L L A+ F I HRP +QL LRIG+H+GPVCAGVVG KM
Sbjct: 926 VSGLPVRNGQLHAREVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKM 985
Query: 183 PRYCLFGDTVNTSSRMESNGRPLKIHISHSTMEVLKSFKTFIMSERGEVEMKGKGVQLTY 362
PRYCLFGDTVNT+SRMESNG LKIH+S T VL+ F F + RG+VEMKGKG TY
Sbjct: 986 PRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFDGFELELRGDVEMKGKGKVRTY 1045
Query: 363 WLHGE 377
WL GE
Sbjct: 1046 WLLGE 1050
>sp|P18293|ANPRA_MOUSE Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA)
(GC-A) (Guanylate cyclase) (NPR-A) (Atrial natriuretic
peptide A-type receptor)
Length = 1057
Score = 170 bits (431), Expect = 2e-42
Identities = 84/125 (67%), Positives = 96/125 (76%)
Frame = +3
Query: 3 VSGLPNINGKLHAREIARMCLQFLSAIFRFVIPHRPNKQLELRIGVHSGPVCAGVVGHKM 182
VSGLP NG+LHARE+ARM L L A+ F I HRP +QL LRIG+H+GPVCAGVVG KM
Sbjct: 926 VSGLPVRNGQLHAREVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKM 985
Query: 183 PRYCLFGDTVNTSSRMESNGRPLKIHISHSTMEVLKSFKTFIMSERGEVEMKGKGVQLTY 362
PRYCLFGDTVNT+SRMESNG L+IH+S T VL+ F F + RG+VEMKGKG TY
Sbjct: 986 PRYCLFGDTVNTASRMESNGEALRIHLSSETKAVLEEFDGFELELRGDVEMKGKGKVRTY 1045
Query: 363 WLHGE 377
WL GE
Sbjct: 1046 WLLGE 1050
>sp|P16066|ANPRA_HUMAN Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA)
(GC-A) (Guanylate cyclase) (NPR-A) (Atrial natriuretic
peptide A-type receptor)
Length = 1061
Score = 168 bits (426), Expect = 8e-42
Identities = 84/125 (67%), Positives = 95/125 (76%)
Frame = +3
Query: 3 VSGLPNINGKLHAREIARMCLQFLSAIFRFVIPHRPNKQLELRIGVHSGPVCAGVVGHKM 182
VSGLP NG+LHA E+ARM L L A+ F I HRP +QL LRIG+H+GPVCAGVVG KM
Sbjct: 930 VSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKM 989
Query: 183 PRYCLFGDTVNTSSRMESNGRPLKIHISHSTMEVLKSFKTFIMSERGEVEMKGKGVQLTY 362
PRYCLFGDTVNT+SRMESNG LKIH+S T VL+ F F + RG+VEMKGKG TY
Sbjct: 990 PRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTY 1049
Query: 363 WLHGE 377
WL GE
Sbjct: 1050 WLLGE 1054
>sp|P46197|ANPRB_BOVIN Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB)
(GC-B) (Guanylate cyclase B) (NPR-B) (Atrial natriuretic
peptide B-type receptor)
Length = 1047
Score = 167 bits (422), Expect = 2e-41
Identities = 83/125 (66%), Positives = 94/125 (75%)
Frame = +3
Query: 3 VSGLPNINGKLHAREIARMCLQFLSAIFRFVIPHRPNKQLELRIGVHSGPVCAGVVGHKM 182
VSGLP NG+ HA EIARM L L A+ F I HRP+ QL LRIGVH+GPVCAGVVG KM
Sbjct: 915 VSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKM 974
Query: 183 PRYCLFGDTVNTSSRMESNGRPLKIHISHSTMEVLKSFKTFIMSERGEVEMKGKGVQLTY 362
PRYCLFGDTVNT+SRMESNG+ LKIH+S +T + L F + RG+VEMKGKG TY
Sbjct: 975 PRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTY 1034
Query: 363 WLHGE 377
WL GE
Sbjct: 1035 WLLGE 1039
>sp|P16067|ANPRB_RAT Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB)
(GC-B) (Guanylate cyclase B) (NPR-B) (Atrial natriuretic
peptide B-type receptor)
Length = 1047
Score = 167 bits (422), Expect = 2e-41
Identities = 83/125 (66%), Positives = 94/125 (75%)
Frame = +3
Query: 3 VSGLPNINGKLHAREIARMCLQFLSAIFRFVIPHRPNKQLELRIGVHSGPVCAGVVGHKM 182
VSGLP NG+ HA EIARM L L A+ F I HRP+ QL LRIGVH+GPVCAGVVG KM
Sbjct: 915 VSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKM 974
Query: 183 PRYCLFGDTVNTSSRMESNGRPLKIHISHSTMEVLKSFKTFIMSERGEVEMKGKGVQLTY 362
PRYCLFGDTVNT+SRMESNG+ LKIH+S +T + L F + RG+VEMKGKG TY
Sbjct: 975 PRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTY 1034
Query: 363 WLHGE 377
WL GE
Sbjct: 1035 WLLGE 1039
>sp|P20594|ANPRB_HUMAN Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB)
(GC-B) (Guanylate cyclase B) (NPR-B) (Atrial natriuretic
peptide B-type receptor)
Length = 1047
Score = 167 bits (422), Expect = 2e-41
Identities = 83/125 (66%), Positives = 94/125 (75%)
Frame = +3
Query: 3 VSGLPNINGKLHAREIARMCLQFLSAIFRFVIPHRPNKQLELRIGVHSGPVCAGVVGHKM 182
VSGLP NG+ HA EIARM L L A+ F I HRP+ QL LRIGVH+GPVCAGVVG KM
Sbjct: 915 VSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKM 974
Query: 183 PRYCLFGDTVNTSSRMESNGRPLKIHISHSTMEVLKSFKTFIMSERGEVEMKGKGVQLTY 362
PRYCLFGDTVNT+SRMESNG+ LKIH+S +T + L F + RG+VEMKGKG TY
Sbjct: 975 PRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTY 1034
Query: 363 WLHGE 377
WL GE
Sbjct: 1035 WLLGE 1039
>sp|P55202|ANPRB_ANGJA Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB)
(GC-B) (Guanylate cyclase) (NPR-B) (Atrial natriuretic
peptide B-type receptor)
Length = 1050
Score = 166 bits (420), Expect = 4e-41
Identities = 84/125 (67%), Positives = 93/125 (74%)
Frame = +3
Query: 3 VSGLPNINGKLHAREIARMCLQFLSAIFRFVIPHRPNKQLELRIGVHSGPVCAGVVGHKM 182
VS + NGKLHAREIA M L L + F I HRPN QL LRIG+H+GPVCAGVVG KM
Sbjct: 919 VSDSQSRNGKLHAREIAGMSLALLEQVKTFKIRHRPNDQLRLRIGIHTGPVCAGVVGLKM 978
Query: 183 PRYCLFGDTVNTSSRMESNGRPLKIHISHSTMEVLKSFKTFIMSERGEVEMKGKGVQLTY 362
PRYCLFGDTVNT+SRMESNG LKIH+S +T EVL F F + RG+VEMKGKG TY
Sbjct: 979 PRYCLFGDTVNTASRMESNGEALKIHLSSATKEVLDEFGYFDLQLRGDVEMKGKGKMRTY 1038
Query: 363 WLHGE 377
WL GE
Sbjct: 1039 WLLGE 1043
>sp|Q6VVW5|ANPRB_MOUSE Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB)
(GC-B) (Guanylate cyclase B) (NPR-B) (Atrial natriuretic
peptide B-type receptor)
Length = 1047
Score = 164 bits (416), Expect = 1e-40
Identities = 82/125 (65%), Positives = 93/125 (74%)
Frame = +3
Query: 3 VSGLPNINGKLHAREIARMCLQFLSAIFRFVIPHRPNKQLELRIGVHSGPVCAGVVGHKM 182
VSGLP NG+ HA EIARM L L A+ F I HRP+ QL LRIGVH+GPVCAGVVG KM
Sbjct: 915 VSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKM 974
Query: 183 PRYCLFGDTVNTSSRMESNGRPLKIHISHSTMEVLKSFKTFIMSERGEVEMKGKGVQLTY 362
PRYCLFGDTVNT+SR ESNG+ LKIH+S +T + L F + RG+VEMKGKG TY
Sbjct: 975 PRYCLFGDTVNTASRKESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTY 1034
Query: 363 WLHGE 377
WL GE
Sbjct: 1035 WLLGE 1039
>sp|Q6TL19|GUC2G_MOUSE Guanylate cyclase 2G precursor (Guanylyl cyclase receptor G) (mGC-G)
Length = 1100
Score = 146 bits (369), Expect = 3e-35
Identities = 75/134 (55%), Positives = 93/134 (69%)
Frame = +3
Query: 6 SGLPNINGKLHAREIARMCLQFLSAIFRFVIPHRPNKQLELRIGVHSGPVCAGVVGHKMP 185
SGLP NG HA EIA M L LS F I H P ++L+LRIG+H+GPV AGVVG MP
Sbjct: 956 SGLPIRNGAQHADEIATMALHLLSVTTHFQIGHMPEERLKLRIGLHTGPVVAGVVGITMP 1015
Query: 186 RYCLFGDTVNTSSRMESNGRPLKIHISHSTMEVLKSFKTFIMSERGEVEMKGKGVQLTYW 365
RYCLFGDTVN +SRMES+ PL+IH+S ST L + + + +RG + +KGKG Q T+W
Sbjct: 1016 RYCLFGDTVNMASRMESSSLPLRIHVSQSTAGALLAAGGYHLQKRGTISVKGKGEQTTFW 1075
Query: 366 LHGEDDFIVDPVPE 407
L G+D F V P+PE
Sbjct: 1076 LKGKDGFPV-PLPE 1088
>sp|P55205|GUC2G_RAT Guanylate cyclase 2G precursor (Guanylyl cyclase receptor G) (GC-G)
(Kinase-like domain containing soluble guanylyl cyclase)
(ksGC)
Length = 1100
Score = 146 bits (368), Expect = 4e-35
Identities = 75/134 (55%), Positives = 92/134 (68%)
Frame = +3
Query: 6 SGLPNINGKLHAREIARMCLQFLSAIFRFVIPHRPNKQLELRIGVHSGPVCAGVVGHKMP 185
SGLP NG HA EIA M L LS F I H P ++L+LRIG+H+GPV AGVVG MP
Sbjct: 956 SGLPIRNGAQHADEIATMSLHLLSVTTNFQIGHMPEERLKLRIGLHTGPVVAGVVGITMP 1015
Query: 186 RYCLFGDTVNTSSRMESNGRPLKIHISHSTMEVLKSFKTFIMSERGEVEMKGKGVQLTYW 365
RYCLFGDTVN +SRMES+ PL+IH+S ST L + + +RG + +KGKG Q T+W
Sbjct: 1016 RYCLFGDTVNMASRMESSSLPLRIHVSQSTARALLVAGGYHLQKRGTISVKGKGEQTTFW 1075
Query: 366 LHGEDDFIVDPVPE 407
L G+D F V P+PE
Sbjct: 1076 LTGKDGFAV-PLPE 1088
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,764,342
Number of Sequences: 369166
Number of extensions: 1446232
Number of successful extensions: 3200
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3040
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3155
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4275400980
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)