Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_O23
(716 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8WXA9|SFR12_HUMAN Splicing factor, arginine/serine-rich... 55 2e-07
sp|P35662|CYL1_BOVIN Cylicin-1 (Cylicin I) (Multiple-band p... 54 5e-07
sp|O01159|RSP7_CAEEL Probable splicing factor, arginine/ser... 51 4e-06
sp|P40631|MLH_TETTH Micronuclear linker histone polyprotein... 49 2e-05
sp|P35663|CYLC1_HUMAN Cylicin-1 (Cylicin I) (Multiple-band ... 49 2e-05
sp|Q8BZX4|SFR12_MOUSE Splicing factor, arginine/serine-rich... 48 3e-05
sp|Q5T200|K0853_HUMAN Protein KIAA0853 48 3e-05
sp|P49756|RBM25_HUMAN Probable RNA-binding protein 25 (RNA-... 47 4e-05
sp|Q9JKL7|SFR12_RAT Splicing factor, arginine/serine-rich 1... 47 5e-05
sp|P54705|SNWA_DICDI Protein snwA 47 7e-05
>sp|Q8WXA9|SFR12_HUMAN Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich
splicing regulatory protein 86) (SRrp86) (Splicing
regulatory protein 508) (SRrp508)
Length = 508
Score = 55.1 bits (131), Expect = 2e-07
Identities = 50/167 (29%), Positives = 76/167 (45%), Gaps = 10/167 (5%)
Frame = +3
Query: 15 RNKSTN-EFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKS-EFDRDDR 188
+NK + E E++ KDK D+ R E ++ DK+ K KE + +S E D +
Sbjct: 297 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 356
Query: 189 KPKSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDDRK 368
K K R +A RS+ + R R S+ K SRS S+ ++K
Sbjct: 357 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSR-NKK 415
Query: 369 DLKRK-----ISEEKDNSMHTSNRQPSGD---KQKLLLHSDTKKRRE 485
D KR+ ISE ++ TS R+ S D K+KL +S + K +E
Sbjct: 416 DKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE 462
Score = 42.4 bits (98), Expect = 0.001
Identities = 41/158 (25%), Positives = 67/158 (42%), Gaps = 3/158 (1%)
Frame = +3
Query: 15 RNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRDDRKP 194
R++S + +R+ T++K +K R E R +++ K +KE + +K DRD +
Sbjct: 252 RSRSHSRDKRKDTREKIKEK--ERVKEKDREKEREREKEREKEKERGKNK---DRDKERE 306
Query: 195 KSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKD---SRSKLYESKDDR 365
K +D DR + ER ++ KD D EK +D R K + D
Sbjct: 307 KDRE----KDKEKDRER---------EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 353
Query: 366 KDLKRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKKR 479
K K K S S + S R S +++ S + R
Sbjct: 354 KRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 391
Score = 33.5 bits (75), Expect = 0.58
Identities = 23/104 (22%), Positives = 42/104 (40%)
Frame = +3
Query: 174 DRDDRKPKSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYES 353
+R + +S+ +R S+ S+R RS + + ++R K K +S
Sbjct: 186 ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 245
Query: 354 KDDRKDLKRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKKRRE 485
++ RK R S +K ++ K+K D +K RE
Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEK-----DREKERE 284
>sp|P35662|CYL1_BOVIN Cylicin-1 (Cylicin I) (Multiple-band polypeptide I)
Length = 667
Score = 53.5 bits (127), Expect = 5e-07
Identities = 36/159 (22%), Positives = 78/159 (49%), Gaps = 6/159 (3%)
Frame = +3
Query: 18 NKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRDDRKPK 197
+K + ++ KD D + + + + +TD ++ + + DS+ K + +DD+K
Sbjct: 366 SKDAKKDSKKGKKDSKKDNKKKDAKKDAESTDAESGDSKDAKKDSKKGKKDSKKDDKKKD 425
Query: 198 SYRDIDARDS-AGDRSQRLVDSK--PRNERSEQQRKD---NDSEKRFLKDSRSKLYESKD 359
+ +D ++ D+ +GD DSK ++++ + +KD D++ D++ +SK
Sbjct: 426 AKKDAESTDAESGDSKNAKKDSKKGKKDDKKKDAKKDAVSTDADSESEGDAKKSKKDSKK 485
Query: 360 DRKDLKRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKK 476
D+KDLK K ++K + + D + + D+KK
Sbjct: 486 DKKDLK-KDDQKKPAMKSKESTETESDWESKKVKRDSKK 523
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/156 (22%), Positives = 68/156 (43%)
Frame = +3
Query: 18 NKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRDDRKPK 197
+K + ++E KDK D + + KDA K DS+ K + +D++K
Sbjct: 335 SKDAKKGKKESKKDKKKDAKKDAASDAESGDSKDAKK------DSKKGKKDSKKDNKKKD 388
Query: 198 SYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDDRKDLK 377
+ +D ++ D+ S+ D+K +++ ++ K +D +K KD+ S ES D + K
Sbjct: 389 AKKDAESTDAESGDSK---DAKKDSKKGKKDSKKDDKKKDAKKDAESTDAESGDSKNAKK 445
Query: 378 RKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKKRRE 485
+KD+ + + D KK ++
Sbjct: 446 DSKKGKKDDKKKDAKKDAVSTDADSESEGDAKKSKK 481
Score = 45.4 bits (106), Expect = 1e-04
Identities = 43/175 (24%), Positives = 81/175 (46%), Gaps = 20/175 (11%)
Frame = +3
Query: 21 KSTNEFEREVTKDKGSDKFTRRSYETSRN---TDKDAMKTGKKEMDSRNSKSEFDRD--- 182
K T + ++ K KGSD + S + ++ KD K KK+ +S +++S +D
Sbjct: 281 KPTKKDAKKDAKGKGSDAESVDSKDAKKDKKGATKDTKKGAKKDTESTDAESGDSKDAKK 340
Query: 183 -------DRKPKSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSK 341
D+K + +D + +GD DSK + S++ K D+ K+ + + ++
Sbjct: 341 GKKESKKDKKKDAKKDAASDAESGDSKDAKKDSKKGKKDSKKDNKKKDA-KKDAESTDAE 399
Query: 342 LYESKDDRKDLKR-KISEEKDNSMHTSNRQ------PSGDKQKLLLHSDTKKRRE 485
+SKD +KD K+ K +KD+ + + SGD + D+KK ++
Sbjct: 400 SGDSKDAKKDSKKGKKDSKKDDKKKDAKKDAESTDAESGDSKN--AKKDSKKGKK 452
Score = 37.7 bits (86), Expect = 0.031
Identities = 28/128 (21%), Positives = 65/128 (50%), Gaps = 11/128 (8%)
Frame = +3
Query: 9 DIRNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTG---KKEMDSRNSKSEFDR 179
D + + +++ K K DK + + + + +TD D+ G K + DS+ K + +
Sbjct: 434 DAESGDSKNAKKDSKKGKKDDK-KKDAKKDAVSTDADSESEGDAKKSKKDSKKDKKDLKK 492
Query: 180 DDRKPKSYRDIDARDSAGDRSQRLV--DSKPRNERSEQQRKDND------SEKRFLKDSR 335
DD+K + + ++ ++ D + V DSK +++ ++ ++ S KR+LK +
Sbjct: 493 DDQKKPAMKSKESTETESDWESKKVKRDSKKDTKKTAKKATESSGAESDVSSKRYLK--K 550
Query: 336 SKLYESKD 359
+++++S D
Sbjct: 551 TEMFKSSD 558
Score = 35.8 bits (81), Expect = 0.12
Identities = 28/128 (21%), Positives = 54/128 (42%)
Frame = +3
Query: 96 TSRNTDKDAMKTGKKEMDSRNSKSEFDRDDRKPKSYRDIDARDSAGDRSQRLVDSKPRNE 275
+ N+ K K KK+ + S +E +D++D+ D+ D+K +
Sbjct: 275 SQNNSKKPTKKDAKKDAKGKGSDAE------------SVDSKDAKKDKKGATKDTK---K 319
Query: 276 RSEQQRKDNDSEKRFLKDSRSKLYESKDDRKDLKRKISEEKDNSMHTSNRQPSGDKQKLL 455
+++ + D+E KD++ ESK D+K +K + S + + + K K
Sbjct: 320 GAKKDTESTDAESGDSKDAKKGKKESKKDKKKDAKKDAASDAESGDSKDAKKDSKKGKKD 379
Query: 456 LHSDTKKR 479
D KK+
Sbjct: 380 SKKDNKKK 387
Score = 31.2 bits (69), Expect = 2.9
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 10/113 (8%)
Frame = +3
Query: 99 SRNTDKDAMKTGKKEMDSRNSKSEFDRDDRKPKSYRDIDARDSAGDRSQRLVDSKPRNER 278
S+ D +T K++ +++ D KPK D S +L SK +
Sbjct: 133 SKKYKDDKKETALKKISKKDTGPH--EVDEKPKRRNKADKTPSKSSHGSQL--SKKSKSK 188
Query: 279 SEQQRKDNDS----------EKRFLKDSRSKLYESKDDRKDLKRKISEEKDNS 407
SE + DS EKR+ KDS+ +ES +K K K+NS
Sbjct: 189 SETNPESKDSISVSIKHQKKEKRYSKDSKEMDFESTSTKKYSK----SSKNNS 237
>sp|O01159|RSP7_CAEEL Probable splicing factor, arginine/serine-rich 7 (p54)
Length = 452
Score = 50.8 bits (120), Expect = 4e-06
Identities = 42/133 (31%), Positives = 70/133 (52%), Gaps = 2/133 (1%)
Frame = +3
Query: 54 KDKGSDKFTRRSYET-SRNTDKDAMKTGKKEMDSRNSKSEFDRDDRKPKSYRDIDARDSA 230
+D+ D+ RRS + SR+ D+D ++ D + S+S RD ++ RD RD
Sbjct: 295 RDRDRDRDRRRSRDRRSRSRDRD------RDRDRKRSRS---RDRKRRSRSRDNKDRDRK 345
Query: 231 GDRSQ-RLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDDRKDLKRKISEEKDNS 407
RS+ R SK R+ + E+ R + KR K SRS+ E + D++D K +E+K+N
Sbjct: 346 RSRSRDRRRRSKSRDRKRERSRSRSKDRKRDKKRSRSRSPEKRRDKEDRK---TEKKENE 402
Query: 408 MHTSNRQPSGDKQ 446
+S R+ +K+
Sbjct: 403 NESSLREKLLEKK 415
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/144 (23%), Positives = 65/144 (45%), Gaps = 1/144 (0%)
Frame = +3
Query: 21 KSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRDDRKPKS 200
++ E E + + D RR SR+ + + ++ DSR+ + DRD R+ +
Sbjct: 252 QALGEIEEAIRMGRNGDDRDRRR---SRSPRRRRSPSPRRRRDSRDRDRDRDRDRRRSRD 308
Query: 201 YRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDDRKDLKR 380
R +RD DR ++ S+ R RS + + KR R + +S+D +++ R
Sbjct: 309 RRS-RSRDRDRDRDRKRSRSRDRKRRSRSRDNKDRDRKRSRSRDRRRRSKSRDRKRERSR 367
Query: 381 KISEE-KDNSMHTSNRQPSGDKQK 449
S++ K + + +R P + K
Sbjct: 368 SRSKDRKRDKKRSRSRSPEKRRDK 391
Score = 45.4 bits (106), Expect = 1e-04
Identities = 33/123 (26%), Positives = 55/123 (44%)
Frame = +3
Query: 114 KDAMKTGKKEMDSRNSKSEFDRDDRKPKSYRDIDARDSAGDRSQRLVDSKPRNERSEQQR 293
++A++ G+ D +S R R P R D+RD DR + S+ R RS +
Sbjct: 258 EEAIRMGRNGDDRDRRRSRSPRRRRSPSPRRRRDSRDRDRDRDRDRRRSRDRRSRSRDRD 317
Query: 294 KDNDSEKRFLKDSRSKLYESKDDRKDLKRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTK 473
+D D ++ +D + + D KD RK S +D R S D+++ S +K
Sbjct: 318 RDRDRKRSRSRDRKRR--SRSRDNKDRDRKRSRSRDR----RRRSKSRDRKRERSRSRSK 371
Query: 474 KRR 482
R+
Sbjct: 372 DRK 374
Score = 44.7 bits (104), Expect = 3e-04
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
Frame = +3
Query: 84 RSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRD-DRKPKSYRDIDARDSAGDRSQRLVDS 260
R SR+ D+D + ++ D R+ + DRD DRK RD R + D R
Sbjct: 287 RRRRDSRDRDRDRDRDRRRSRDRRSRSRDRDRDRDRKRSRSRDRKRRSRSRDNKDR---- 342
Query: 261 KPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDDRKDLKRKISEEKDNSMHTSNRQ 428
+ RS +R+ + S R + SRS+ SKD ++D KR S + +R+
Sbjct: 343 DRKRSRSRDRRRRSKSRDRKRERSRSR---SKDRKRDKKRSRSRSPEKRRDKEDRK 395
>sp|P40631|MLH_TETTH Micronuclear linker histone polyprotein (MIC LH) [Contains:
Micronuclear linker histone-alpha; Micronuclear linker
histone-beta; Micronuclear linker histone-delta;
Micronuclear linker histone-gamma]
Length = 633
Score = 48.5 bits (114), Expect = 2e-05
Identities = 41/163 (25%), Positives = 69/163 (42%), Gaps = 18/163 (11%)
Frame = +3
Query: 15 RNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRD---- 182
RN S++ +K+K S + +S+ K + G+K S+N KS +D
Sbjct: 259 RNSSSSSKRSSSSKNKKSSSSKNKKSSSSKGR-KSSSSRGRKASSSKNRKSSKSKDRKSS 317
Query: 183 ---DRKPKSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRK----------DNDSEKRFL 323
RK S + R ++ R ++ SK R Q+RK +++ +KR
Sbjct: 318 SSKGRKSSSSSKSNKRKASSSRGRKSSSSKGRKSSKSQERKNSHADTSKQMEDEGQKRRQ 377
Query: 324 KDSRSKLYE-SKDDRKDLKRKISEEKDNSMHTSNRQPSGDKQK 449
S +K E SK R++ ++ +K N+ S SG K K
Sbjct: 378 SSSSAKRDESSKKSRRNSMKEARTKKANNKSASKASKSGSKSK 420
Score = 38.9 bits (89), Expect = 0.014
Identities = 38/148 (25%), Positives = 56/148 (37%), Gaps = 2/148 (1%)
Frame = +3
Query: 39 EREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRDDRKPKSYRDIDA 218
E +V +D ++ + E + +K KK+ +NS S+ R K KS
Sbjct: 141 EVKVYEDAYQKEYAQYLVEFKKWNEKYGQAAQKKQTKRKNSTSKSRRSSSKGKS------ 194
Query: 219 RDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDDR--KDLKRKISE 392
S + SK R + S Q + S +R K SKD + + RK S
Sbjct: 195 --SVSKGRTKSTSSKRRADSSASQGRSQSS-----SSNRRKASSSKDQKGTRSSSRKASN 247
Query: 393 EKDNSMHTSNRQPSGDKQKLLLHSDTKK 476
K TSN++ S K S KK
Sbjct: 248 SKGRKNSTSNKRNSSSSSKRSSSSKNKK 275
Score = 37.4 bits (85), Expect = 0.040
Identities = 32/149 (21%), Positives = 62/149 (41%), Gaps = 1/149 (0%)
Frame = +3
Query: 6 KDIRNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRDD 185
KD+ N+ +N + +K K + K RS S++ K K + D+ N
Sbjct: 483 KDMVNEKSNS--KSSSKGKKNSKSNTRSKSKSKSASKSRKNASKSKKDTTNHG------- 533
Query: 186 RKPKSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDDR 365
R ++ + +S+ +KP N+ ++ +S R ++SRS+ + D+
Sbjct: 534 ------RQTRSKSRSESKSKSEAPNKPSNKMEVIEQPKEESSDRKRRESRSQSAKKTSDK 587
Query: 366 KDLKRKISEEKD-NSMHTSNRQPSGDKQK 449
K R S++ +N + S K+K
Sbjct: 588 KSKNRSDSKKMTAEDPKKNNAEDSKGKKK 616
>sp|P35663|CYLC1_HUMAN Cylicin-1 (Cylicin I) (Multiple-band polypeptide I)
Length = 651
Score = 48.5 bits (114), Expect = 2e-05
Identities = 43/176 (24%), Positives = 81/176 (46%), Gaps = 16/176 (9%)
Frame = +3
Query: 3 DKDIRNKSTNEFEREVTK-DKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDR 179
D +RN S N + K K + K T+++ + S + + + K KK DS+ K +
Sbjct: 262 DAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKK--DSKKVKKNVKK 319
Query: 180 DDRKPKSYRDIDARDS-AGDRSQRLVDSK--PRNERSEQQRKD-------NDSEKRFLKD 329
DD+K +D ++ D+ +GD D+K + + + ++KD D+E KD
Sbjct: 320 DDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKD 379
Query: 330 SRS-----KLYESKDDRKDLKRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKKRR 482
+R+ K DD+K +KI+ D+ +++ D++K S T ++
Sbjct: 380 ARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKK 435
Score = 46.2 bits (108), Expect = 9e-05
Identities = 45/173 (26%), Positives = 77/173 (44%), Gaps = 12/173 (6%)
Frame = +3
Query: 3 DKDIRNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRD 182
D K T + ++++ KD K + Y S +T+ K + DSRN K D
Sbjct: 339 DSKDERKDTKKDKKKLKKD--DKKKDTKKYPESTDTESGDAKDARN--DSRNLKKASKND 394
Query: 183 DRK---------PKSYRDIDARDSAGDRSQRLVDSKPRNERS---EQQRKDNDSEKRFLK 326
D+K S ++++++S D + DSK N++S +++ D DSE +
Sbjct: 395 DKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPK--G 452
Query: 327 DSRSKLYESKDDRKDLKRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKKRRE 485
DS+ + K +KD K K ++KD + + + D L L D K +E
Sbjct: 453 DSKKGKKDEKKGKKDSK-KDDKKKDAKKNAESTEMESD---LELKKDKKHSKE 501
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 2/134 (1%)
Frame = +3
Query: 6 KDIRNKSTNEFEREVTKDKGSD--KFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDR 179
KD RN S N + DK D K T + S K++ K KK D ++SK++ +
Sbjct: 378 KDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKK--DKKDSKTDNKK 435
Query: 180 DDRKPKSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKD 359
+ + D D+ + GD + D K + S++ K D++K E K
Sbjct: 436 SVKNDEESTDADS-EPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKK 494
Query: 360 DRKDLKRKISEEKD 401
D+K K K +KD
Sbjct: 495 DKKHSKEKKGSKKD 508
>sp|Q8BZX4|SFR12_MOUSE Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich
splicing regulatory protein 86) (SRrp86)
Length = 494
Score = 47.8 bits (112), Expect = 3e-05
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 2/149 (1%)
Frame = +3
Query: 3 DKDIRNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRD 182
DKD + +E ER+ K+K DK R + S+ TD+ KKE SR ++
Sbjct: 301 DKDREKEKDHEKERDKEKEKEQDKDKEREKDRSKETDEKR----KKEKKSRTPPRSYNAS 356
Query: 183 DRKPKSYRDIDARDS-AGDRSQRLVDS-KPRNERSEQQRKDNDSEKRFLKDSRSKLYESK 356
R + R+ R S + RS R + K ++ RS R N EK+
Sbjct: 357 RRSRSTSRERRRRRSRSSSRSPRTSKTVKRKSSRSPSPRGRNKKEKK------------- 403
Query: 357 DDRKDLKRKISEEKDNSMHTSNRQPSGDK 443
R+ + IS+ ++ TS ++ SGD+
Sbjct: 404 --REKERDHISDRRERERSTSTKKSSGDR 430
Score = 38.9 bits (89), Expect = 0.014
Identities = 34/157 (21%), Positives = 69/157 (43%)
Frame = +3
Query: 15 RNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRDDRKP 194
R+KS + + + + K RS+ SR+ KD ++ K + SKS R+ RK
Sbjct: 200 RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS--KSPHKKRSKS---RERRKS 254
Query: 195 KSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDDRKDL 374
+S +RD D +++ ER +++ ++ + E+ KD K+ KD
Sbjct: 255 RSRSR--SRDKRKDTREKV------KERVKEKEREKERERE--KDREKDKERGKNKDKDR 304
Query: 375 KRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKKRRE 485
+++ EK+ Q +++ +T ++R+
Sbjct: 305 EKEKDHEKERDKEKEKEQDKDKEREKDRSKETDEKRK 341
>sp|Q5T200|K0853_HUMAN Protein KIAA0853
Length = 1668
Score = 47.8 bits (112), Expect = 3e-05
Identities = 39/161 (24%), Positives = 73/161 (45%)
Frame = +3
Query: 3 DKDIRNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRD 182
++D + E ERE +++ ++ R E R+ D D + ++E D R + E +R+
Sbjct: 696 ERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERD-REKERERERE 754
Query: 183 DRKPKSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDD 362
+R+ + R+ R+ +R + ++ R++ E+QR D +K D R K E ++D
Sbjct: 755 ERERERERE---RERERERERERERARERDKERERQRDWEDKDKG-RDDRREKREEIRED 810
Query: 363 RKDLKRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKKRRE 485
R + E K + + PS K+RRE
Sbjct: 811 RNP-RDGHDERKSKKRYRNEGSPSP-------RQSPKRRRE 843
Score = 44.3 bits (103), Expect = 3e-04
Identities = 38/140 (27%), Positives = 65/140 (46%), Gaps = 2/140 (1%)
Frame = +3
Query: 12 IRNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRDDRK 191
+R K ++ ER + D+ R +T D++ ++E + S S RDDR+
Sbjct: 395 MREKGRHDHERT---SQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDRE 451
Query: 192 PKSYRD-IDARDSAGDRSQRLVDSKPRNERSEQQRKDNDS-EKRFLKDSRSKLYESKDDR 365
P+ RD DARD+ R R DS+ + E + D+ E R +DSRS D
Sbjct: 452 PRDGRDRRDARDTRDRRELR--DSRDMRDSREMRDYSRDTKESRDPRDSRST--RDAHDY 507
Query: 366 KDLKRKISEEKDNSMHTSNR 425
+D + + + K+++ +R
Sbjct: 508 RDREGRDTHRKEDTYPEESR 527
Score = 42.0 bits (97), Expect = 0.002
Identities = 37/159 (23%), Positives = 67/159 (42%), Gaps = 2/159 (1%)
Frame = +3
Query: 15 RNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRDDRKP 194
R + E ERE +++ ++ R E +R DK+ + +++ + ++ RDDR+
Sbjct: 749 REREREERERERERERERERERERERERARERDKERER--QRDWEDKDK----GRDDRRE 802
Query: 195 KSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDDRKDL 374
K + R+ +R + RNE S R+ + DS + Y S DD+ +
Sbjct: 803 KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDA--YNSGDDKNEK 860
Query: 375 KRKISE--EKDNSMHTSNRQPSGDKQKLLLHSDTKKRRE 485
R +S+ S S + D+Q D K R+
Sbjct: 861 HRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERK 899
Score = 34.3 bits (77), Expect = 0.34
Identities = 38/140 (27%), Positives = 61/140 (43%), Gaps = 18/140 (12%)
Frame = +3
Query: 15 RNKSTNEFEREVTKDKGSDKFTR--------RSYETSRNT-DKDAMKTGKKEMDSRNSK- 164
R K + E ERE +D+ S + R R +R+T D+ ++ + DSR +
Sbjct: 426 REKDSRE-EREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRD 484
Query: 165 ----SEFDRDDRKPKSYRDI-DARDSAGDRSQRLVDSKPRNERS--EQQRKDNDSEKRFL 323
++ RD R +S RD D RD G + R D+ P RS ++ S
Sbjct: 485 YSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIR 544
Query: 324 KDSRSK-LYESKDDRKDLKR 380
+SR++ E ++DR R
Sbjct: 545 NESRNESRSEIRNDRMGRSR 564
Score = 31.2 bits (69), Expect = 2.9
Identities = 38/177 (21%), Positives = 68/177 (38%), Gaps = 28/177 (15%)
Frame = +3
Query: 39 EREVTKDKGSDKFTRRSYETSR--NTDKDAM---------KTGKKEMDSRNSKSEFDR-D 182
ER+ F RR E R N ++D + + E D R + DR D
Sbjct: 610 ERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 669
Query: 183 DRKPKSYRDIDA---------------RDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKR 317
DR+ + R+ D RD ++ + L + R ER ++ K+ D E+
Sbjct: 670 DRRDERARERDRERERDRERERERERERDREREKERELERERAR-EREREREKERDRERD 728
Query: 318 FLKD-SRSKLYESKDDRKDLKRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKKRRE 485
+D R + E + DR+ + + EE++ + +++ + K RE
Sbjct: 729 RDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERE 785
Score = 30.8 bits (68), Expect = 3.8
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 14/164 (8%)
Frame = +3
Query: 18 NKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKS-EFDRDDRKP 194
N + N F E + K + ET T +DA +K MD + S S +R +R
Sbjct: 1145 NTTNNTFANEDSHRK-CHRTRVEKVETPHVTIEDAQH--RKPMDQKRSSSLGSNRSNRSH 1201
Query: 195 KSYR-----DIDARDSAGDRS--QRLVDSKPRNERSEQ------QRKDNDSEKRFLKDSR 335
S R + A S D+S +R++ S R+ + +RK + + + SR
Sbjct: 1202 TSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSR 1261
Query: 336 SKLYESKDDRKDLKRKISEEKDNSMHTSNRQPSGDKQKLLLHSD 467
S + +D R R+ S E D +H +R S D + L D
Sbjct: 1262 STSSDRQDSRSHSSRRSSPESDRQVH--SRSGSFDSRDRLQERD 1303
>sp|P49756|RBM25_HUMAN Probable RNA-binding protein 25 (RNA-binding motif protein 25)
(RNA-binding region containing protein 7) (Protein S164)
Length = 784
Score = 47.4 bits (111), Expect = 4e-05
Identities = 38/142 (26%), Positives = 69/142 (48%), Gaps = 14/142 (9%)
Frame = +3
Query: 15 RNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRD-DRK 191
R + E ERE +++ +K R E R+ D+D K ++ D E DRD DR+
Sbjct: 259 RERERREREREREREREREKEKERERERERDRDRDRTKERDRDRD-----RERDRDRDRE 313
Query: 192 PKSYRDID---ARDSAGDRS-------QRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSK 341
S R+ D +R+ + DR +R + + ER ++ ++ + E+ KD +
Sbjct: 314 RSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRD 373
Query: 342 LYESKDD---RKDLKRKISEEK 398
E ++D R+ L+RK+ E++
Sbjct: 374 REEDEEDAYERRKLERKLREKE 395
Score = 39.7 bits (91), Expect = 0.008
Identities = 27/154 (17%), Positives = 69/154 (44%), Gaps = 4/154 (2%)
Frame = +3
Query: 3 DKDIRNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRD 182
D++ + E ERE +++ ++ R E R +KD + +++ + + + +R
Sbjct: 331 DREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK 390
Query: 183 DRKPKSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDD 362
R+ ++ ++ ++ + + ER E++R++ E + LK+ + +DD
Sbjct: 391 LREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDD 450
Query: 363 RKDLK----RKISEEKDNSMHTSNRQPSGDKQKL 452
K + +K +++ M R +K++L
Sbjct: 451 PKYYRGSALQKRLRDREKEMEADERDRKREKEEL 484
Score = 37.4 bits (85), Expect = 0.040
Identities = 32/144 (22%), Positives = 62/144 (43%), Gaps = 2/144 (1%)
Frame = +3
Query: 3 DKDIRNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRD 182
+K + K E E+E + + + R E R +++ + +KE + E +RD
Sbjct: 235 EKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERER-----ERERD 289
Query: 183 -DRKPKSYRDIDARDSAGDRSQRLVDSKPRN-ERSEQQRKDNDSEKRFLKDSRSKLYESK 356
DR RD D RD DR + S RN +RS + K D E+ ++ + +
Sbjct: 290 RDRDRTKERDRD-RDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERER 348
Query: 357 DDRKDLKRKISEEKDNSMHTSNRQ 428
+ ++ +R+ E++ ++
Sbjct: 349 EREREREREREREREREREKDKKR 372
Score = 35.8 bits (81), Expect = 0.12
Identities = 34/169 (20%), Positives = 67/169 (39%), Gaps = 8/169 (4%)
Frame = +3
Query: 3 DKDIRNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRD 182
+++ + E ERE KDK D+ E + K K +KE + ++
Sbjct: 351 EREREREREREREREREKDKKRDR--EEDEEDAYERRKLERKLREKEAAYQERLKNWEIR 408
Query: 183 DRKPKSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRF--------LKDSRS 338
+RK + +A R + ++K E E D D K + L+D
Sbjct: 409 ERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREK 468
Query: 339 KLYESKDDRKDLKRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKKRRE 485
++ + DRK K ++ E + + + P + Q+ + + ++RR+
Sbjct: 469 EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQR--MEQEAERRRQ 515
Score = 31.2 bits (69), Expect = 2.9
Identities = 27/161 (16%), Positives = 66/161 (40%), Gaps = 1/161 (0%)
Frame = +3
Query: 6 KDIRNKSTNEFERE-VTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRD 182
+DI E +R+ ++++ + T + E + + + +KE R + E +R+
Sbjct: 203 EDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERE 262
Query: 183 DRKPKSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDD 362
R+ + R+ + +R + +R++++ +D D E+ +D S D
Sbjct: 263 RREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRE----RSSDR 318
Query: 363 RKDLKRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKKRRE 485
KD R + +D + +++ + ++ RE
Sbjct: 319 NKDRSRSREKSRDRERERERERERERERERERERERERERE 359
>sp|Q9JKL7|SFR12_RAT Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich
splicing regulatory protein 86) (SRrp86) (SR-related
protein of 86 kDa)
Length = 494
Score = 47.0 bits (110), Expect = 5e-05
Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 2/137 (1%)
Frame = +3
Query: 3 DKDIRNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRD 182
DKD + +E ER+ K+K DK R + S+ D+ KKE SR ++
Sbjct: 301 DKDREKEKDHEKERDKEKEKEQDKDKEREKDRSKEADEKR----KKEKKSRTPPRSYNSS 356
Query: 183 DRKPKSYRDIDARDS-AGDRSQRLVDS-KPRNERSEQQRKDNDSEKRFLKDSRSKLYESK 356
R + R+ R S + RS R + K ++ RS R N EK+ R K +
Sbjct: 357 RRSRSASRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRGRNKKEKK-----REKERDHI 411
Query: 357 DDRKDLKRKISEEKDNS 407
DR++ +R S +K +S
Sbjct: 412 SDRRERERSTSTKKSSS 428
Score = 43.1 bits (100), Expect = 7e-04
Identities = 36/148 (24%), Positives = 68/148 (45%), Gaps = 1/148 (0%)
Frame = +3
Query: 3 DKDIRNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRD 182
+KD + +RE K+K +K + E ++ DK+ K KE D + K + R
Sbjct: 291 EKDKERGKNKDKDRE--KEKDHEKERDKEKEKEQDKDKEREKDRSKEADEKRKKEKKSR- 347
Query: 183 DRKPKSYRDI-DARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKD 359
P+SY +R ++ +R +R S R+ R+ + K S + R+K + ++
Sbjct: 348 -TPPRSYNSSRRSRSASRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPR-GRNKKEKKRE 405
Query: 360 DRKDLKRKISEEKDNSMHTSNRQPSGDK 443
+D IS+ ++ TS ++ S D+
Sbjct: 406 KERD---HISDRRERERSTSTKKSSSDR 430
Score = 40.8 bits (94), Expect = 0.004
Identities = 41/167 (24%), Positives = 66/167 (39%), Gaps = 10/167 (5%)
Frame = +3
Query: 6 KDIRNKSTNEF-EREVTKDKGSDKFTRRSYETSRNTDKDAMKTG--KKEMDSRNSKSEFD 176
KD R K ERE K+K +K + E +N DKD K +KE D K +
Sbjct: 265 KDTREKVKERVKEREREKEKEREKEREKDKERGKNKDKDREKEKDHEKERDKEKEKEQDK 324
Query: 177 RDDRKPKSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESK 356
+R+ ++ D + +S+ + PR+ S ++ + E+R + S S
Sbjct: 325 DKEREKDRSKEADEKRKKEKKSR----TPPRSYNSSRRSRSASRERRRRRSRSSS--RSP 378
Query: 357 DDRKDLKRKIS-------EEKDNSMHTSNRQPSGDKQKLLLHSDTKK 476
K +KRK S K R D+++ + TKK
Sbjct: 379 RTSKTIKRKSSRSPSPRGRNKKEKKREKERDHISDRRERERSTSTKK 425
Score = 39.3 bits (90), Expect = 0.011
Identities = 31/157 (19%), Positives = 72/157 (45%)
Frame = +3
Query: 15 RNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFDRDDRKP 194
R+KS + + + + K RS+ SR+ KD ++ K + SKS R+ RK
Sbjct: 200 RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRARS--KSPHKKRSKS---RERRKS 254
Query: 195 KSYRDIDARDSAGDRSQRLVDSKPRNERSEQQRKDNDSEKRFLKDSRSKLYESKDDRKDL 374
+S +RD D +++ ER +++ ++ + E+ ++ + ++KD ++
Sbjct: 255 RSRSR--SRDKRKDTREKV------KERVKEREREKEKEREKEREKDKERGKNKDKDREK 306
Query: 375 KRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKKRRE 485
++ +E+D + ++ +D K+++E
Sbjct: 307 EKDHEKERDKEKEKEQDKDKEREKDRSKEADEKRKKE 343
>sp|P54705|SNWA_DICDI Protein snwA
Length = 685
Score = 46.6 bits (109), Expect = 7e-05
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 23/165 (13%)
Frame = +3
Query: 3 DKDIRNKSTNEFEREVTKDKGSDKFTRRSYETSR--------NTDKDAMKTGKKEMDSRN 158
+ D N + N+ + K+K + RRS S N D D K D+R
Sbjct: 368 NSDSDNDNDNDSSSDEDKNKRTPPMNRRSRSRSTERIPSRNDNDDDDDRYRIKDNRDNRG 427
Query: 159 SKSEFDRDDRKPKSYRDI-------DARDSAGDRSQRLVDSKP-RNERSEQQRKDNDSEK 314
+ RD+R + RD D+RDS +R R DS+ R+ R ++R D++
Sbjct: 428 RDNIDSRDNRDSRDSRDSRDSRDSRDSRDSRDNRDSR--DSRDNRDNRDNRRRDDSNDRD 485
Query: 315 RFLK-------DSRSKLYESKDDRKDLKRKISEEKDNSMHTSNRQ 428
R+ K DS S +S+D+R +RK E+D R+
Sbjct: 486 RYSKRRSDSDSDSDSDSSDSEDERVRRERKEKLERDKIRMEKKRE 530
Score = 45.1 bits (105), Expect = 2e-04
Identities = 42/174 (24%), Positives = 79/174 (45%), Gaps = 15/174 (8%)
Frame = +3
Query: 6 KDIRNKSTNEFEREVTKDKGSDKFTRRSYETSRNTDKD---------AMKTGKKEMDSRN 158
+D+RN+ + ++ T+ SD ++S + DK+ + + + SRN
Sbjct: 349 EDVRNERSGIIQQRYTRKDNSDSDNDNDNDSSSDEDKNKRTPPMNRRSRSRSTERIPSRN 408
Query: 159 SKSEFD-----RDDRKPKSYRDIDARDSAGDRSQRLVDSK-PRNERSEQQRKDNDSEKRF 320
+ D +D+R + +ID+RD+ R R DS+ R+ R + +DN R
Sbjct: 409 DNDDDDDRYRIKDNRDNRGRDNIDSRDNRDSRDSR--DSRDSRDSRDSRDSRDN----RD 462
Query: 321 LKDSRSKLYESKDDRKDLKRKISEEKDNSMHTSNRQPSGDKQKLLLHSDTKKRR 482
+DSR +++D+R + +R S ++D S R+ D SD++ R
Sbjct: 463 SRDSR----DNRDNRDNRRRDDSNDRD---RYSKRRSDSDSDSDSDSSDSEDER 509
Score = 37.7 bits (86), Expect = 0.031
Identities = 42/155 (27%), Positives = 66/155 (42%), Gaps = 30/155 (19%)
Frame = +3
Query: 15 RNKSTNEFEREVTKD----KGSDKFTRRSYETSRNTDKDAMKTGKKEMDSRNSKSEFD-R 179
RN + ++ +R KD +G D R SR D + + DSR+S+ D R
Sbjct: 407 RNDNDDDDDRYRIKDNRDNRGRDNIDSRDNRDSR--DSRDSRDSRDSRDSRDSRDNRDSR 464
Query: 180 DDRKPKSYRDIDARDSAGDR---SQRLVDS--------------KPRNERSEQQRKD--- 299
D R + RD RD + DR S+R DS + R ER E+ +D
Sbjct: 465 DSRDNRDNRDNRRRDDSNDRDRYSKRRSDSDSDSDSDSSDSEDERVRRERKEKLERDKIR 524
Query: 300 ----NDSEKRF-LKDSRSKLYESKDDRKDLKRKIS 389
+ E+ + L+ S K ++D +D+ KI+
Sbjct: 525 MEKKRELEREYRLEASGKKSKFNRDQDRDISEKIA 559
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,806,394
Number of Sequences: 369166
Number of extensions: 1225218
Number of successful extensions: 7219
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5199
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6306
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6365071885
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)