Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_O21
(499 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q920R6|VPP4_MOUSE Vacuolar proton translocating ATPase 1... 171 7e-43
sp|Q29466|VPP1_BOVIN Vacuolar proton translocating ATPase 1... 171 1e-42
sp|Q9HBG4|VPP4_HUMAN Vacuolar proton translocating ATPase 1... 171 1e-42
sp|Q5R422|VPP1_PONPY Vacuolar proton translocating ATPase 1... 168 7e-42
sp|Q93050|VPP1_HUMAN Vacuolar proton translocating ATPase 1... 168 7e-42
sp|Q9Z1G4|VPP1_MOUSE Vacuolar proton translocating ATPase 1... 167 1e-41
sp|P25286|VPP1_RAT Vacuolar proton translocating ATPase 116... 167 1e-41
sp|Q13488|VPP3_HUMAN Vacuolar proton translocating ATPase 1... 159 3e-39
sp|O97681|VPP2_BOVIN Vacuolar proton translocating ATPase 1... 155 4e-38
sp|P15920|VPP2_MOUSE Vacuolar proton translocating ATPase 1... 154 1e-37
>sp|Q920R6|VPP4_MOUSE Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4
(V-ATPase 116-kDa isoform a4) (Vacuolar proton
translocating ATPase 116 kDa subunit a kidney isoform)
Length = 833
Score = 171 bits (434), Expect = 7e-43
Identities = 83/115 (72%), Positives = 93/115 (80%)
Frame = +3
Query: 3 IFVHQCIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWQMVLSIGLKQDTLAGSIXX 182
IFVHQ IHTIEYCLGCISNTASYLRLWALSLAHA+LSEVLW MV+SIGL+ AG +
Sbjct: 712 IFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAELSEVLWTMVMSIGLRLQGWAGLVGV 771
Query: 183 XXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEGYKFNPFNFKGV 347
T+A+LL+MEGLSAFLHALRLHWVEFQNKFY+G G KF+PF+FK V
Sbjct: 772 FIIFAVFAVLTVAILLVMEGLSAFLHALRLHWVEFQNKFYEGAGSKFSPFSFKHV 826
>sp|Q29466|VPP1_BOVIN Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1
(V-ATPase 116-kDa isoform a1) (Clathrin-coated
vesicle/synaptic vesicle proton pump 116 kDa subunit)
(Vacuolar proton pump subunit 1) (Vacuolar adenosine
triphosphatase subunit Ac116)
Length = 838
Score = 171 bits (432), Expect = 1e-42
Identities = 82/119 (68%), Positives = 93/119 (78%)
Frame = +3
Query: 9 VHQCIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWQMVLSIGLKQDTLAGSIXXXX 188
VHQ IHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLW MV+ IGLK +LAG +
Sbjct: 719 VHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLKVKSLAGGLALFF 778
Query: 189 XXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEGYKFNPFNFKGVDDLSLD 365
T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G G+KF PF+F+ + + D
Sbjct: 779 IFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFD 837
>sp|Q9HBG4|VPP4_HUMAN Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4
(V-ATPase 116-kDa isoform a4) (Vacuolar proton
translocating ATPase 116 kDa subunit a kidney isoform)
Length = 840
Score = 171 bits (432), Expect = 1e-42
Identities = 81/117 (69%), Positives = 93/117 (79%)
Frame = +3
Query: 3 IFVHQCIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWQMVLSIGLKQDTLAGSIXX 182
+FVHQ IHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLW MV++ GL+ G +
Sbjct: 719 VFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVMNSGLQTRGWGGIVGV 778
Query: 183 XXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEGYKFNPFNFKGVDD 353
T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G+GYKF+PF+FK + D
Sbjct: 779 FIIFAVFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKFYVGDGYKFSPFSFKHILD 835
>sp|Q5R422|VPP1_PONPY Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1
(V-ATPase 116-kDa isoform a1)
Length = 837
Score = 168 bits (425), Expect = 7e-42
Identities = 80/113 (70%), Positives = 90/113 (79%)
Frame = +3
Query: 9 VHQCIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWQMVLSIGLKQDTLAGSIXXXX 188
VHQ IHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLW MV+ IGL +LAG +
Sbjct: 718 VHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLVLFF 777
Query: 189 XXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEGYKFNPFNFKGV 347
T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G G+KF PF+F+ +
Sbjct: 778 FFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHI 830
>sp|Q93050|VPP1_HUMAN Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1
(V-ATPase 116-kDa isoform a1) (Clathrin-coated
vesicle/synaptic vesicle proton pump 116 kDa subunit)
(Vacuolar proton pump subunit 1) (Vacuolar adenosine
triphosphatase subunit Ac116)
Length = 837
Score = 168 bits (425), Expect = 7e-42
Identities = 80/113 (70%), Positives = 90/113 (79%)
Frame = +3
Query: 9 VHQCIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWQMVLSIGLKQDTLAGSIXXXX 188
VHQ IHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLW MV+ IGL +LAG +
Sbjct: 718 VHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLVLFF 777
Query: 189 XXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEGYKFNPFNFKGV 347
T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G G+KF PF+F+ +
Sbjct: 778 FFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHI 830
>sp|Q9Z1G4|VPP1_MOUSE Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1
(V-ATPase 116-kDa isoform a1) (Clathrin-coated
vesicle/synaptic vesicle proton pump 116 kDa subunit)
(Vacuolar proton pump subunit 1) (Vacuolar adenosine
triphosphatase subunit Ac116)
Length = 839
Score = 167 bits (424), Expect = 1e-41
Identities = 81/119 (68%), Positives = 92/119 (77%)
Frame = +3
Query: 9 VHQCIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWQMVLSIGLKQDTLAGSIXXXX 188
VHQ IHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLW MV+ IGL +LAG +
Sbjct: 720 VHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLHVRSLAGGLGLFF 779
Query: 189 XXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEGYKFNPFNFKGVDDLSLD 365
T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G G+KF PF+F+ + + D
Sbjct: 780 IFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTGFKFLPFSFEHIREGKFD 838
>sp|P25286|VPP1_RAT Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1
(V-ATPase 116-kDa isoform a1) (Clathrin-coated
vesicle/synaptic vesicle proton pump 116 kDa subunit)
(Vacuolar proton pump subunit 1) (Vacuolar adenosine
triphosphatase subunit Ac116)
Length = 838
Score = 167 bits (424), Expect = 1e-41
Identities = 81/119 (68%), Positives = 92/119 (77%)
Frame = +3
Query: 9 VHQCIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWQMVLSIGLKQDTLAGSIXXXX 188
VHQ IHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLW MV+ IGL +LAG +
Sbjct: 719 VHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLHVRSLAGGLGLFF 778
Query: 189 XXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEGYKFNPFNFKGVDDLSLD 365
T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G G+KF PF+F+ + + D
Sbjct: 779 IFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTGFKFLPFSFEHIREGKFD 837
>sp|Q13488|VPP3_HUMAN Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3
(V-ATPase 116-kDa isoform a3) (Osteoclastic proton pump
116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune
regulator 1) (T cell immune response cDNA7 protein)
(TIRC7)
Length = 830
Score = 159 bits (403), Expect = 3e-39
Identities = 76/119 (63%), Positives = 89/119 (74%), Gaps = 2/119 (1%)
Frame = +3
Query: 3 IFVHQCIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWQMVLSI--GLKQDTLAGSI 176
+ +HQ IHTIE+CLGC+SNTASYLRLWALSLAHAQLSEVLW MV+ I GL ++ ++
Sbjct: 712 VLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLWAMVMRIGLGLGREVGVAAV 771
Query: 177 XXXXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEGYKFNPFNFKGVDD 353
T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G GYK +PF F DD
Sbjct: 772 VLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGTGYKLSPFTFAATDD 830
>sp|O97681|VPP2_BOVIN Vacuolar proton translocating ATPase 116 kDa subunit A isoform 2
(V-ATPase 116-kDa isoform a2)
Length = 854
Score = 155 bits (393), Expect = 4e-38
Identities = 75/113 (66%), Positives = 87/113 (76%)
Frame = +3
Query: 3 IFVHQCIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWQMVLSIGLKQDTLAGSIXX 182
I + Q IH+IEYCLGCISNTASYLRLWALSLAHAQLSEVLW M++ +GL+ DT G +
Sbjct: 731 ILMTQIIHSIEYCLGCISNTASYLRLWALSLAHAQLSEVLWAMLMHVGLRVDTAYGVLVL 790
Query: 183 XXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEGYKFNPFNFK 341
TI +LL+MEGLSAFLHA+RLHWVEFQNKFY G G KF PF+F+
Sbjct: 791 LPVIAFFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPFSFR 843
>sp|P15920|VPP2_MOUSE Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2
(V-ATPase 116-kDa isoform a2) (Immune suppressor factor
J6B7)
Length = 856
Score = 154 bits (388), Expect = 1e-37
Identities = 74/112 (66%), Positives = 86/112 (76%)
Frame = +3
Query: 3 IFVHQCIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWQMVLSIGLKQDTLAGSIXX 182
I + Q IH+IEYCLGCISNTASYLRLWALSLAHAQLS+VLW M++ +GL+ DT G +
Sbjct: 731 ILMTQAIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAMLMRVGLRVDTTYGVLLL 790
Query: 183 XXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEGYKFNPFNF 338
TI +LL+MEGLSAFLHA+RLHWVEFQNKFY G G KF PF+F
Sbjct: 791 LPVMAFFAVLTIFILLVMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPFSF 842
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,825,756
Number of Sequences: 369166
Number of extensions: 1040822
Number of successful extensions: 2476
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2410
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2471
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3119256630
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)