Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_O20
(505 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O88487|DYI2_MOUSE Dynein intermediate chain 2, cytosolic... 251 9e-67
sp|Q62871|DYI2_RAT Dynein intermediate chain 2, cytosolic (... 251 9e-67
sp|Q13409|DYI2_HUMAN Dynein intermediate chain 2, cytosolic... 249 2e-66
sp|O14576|DYI1_HUMAN Dynein intermediate chain 1, cytosolic... 244 8e-65
sp|Q63100|DYI1_RAT Dynein intermediate chain 1, cytosolic (... 243 1e-64
sp|O88485|DYI1_MOUSE Dynein intermediate chain 1, cytosolic... 238 5e-63
sp|Q24246|DYIN_DROME Dynein intermediate chain, cytosolic (... 230 1e-60
sp|P54703|DYIN_DICDI Dynein intermediate chain, cytosolic (... 171 1e-42
sp|Q16960|DYI3_ANTCR Dynein intermediate chain 3, ciliary 64 2e-10
sp|Q9GZS0|DYI4_HUMAN Dynein intermediate chain 2, axonemal ... 63 3e-10
>sp|O88487|DYI2_MOUSE Dynein intermediate chain 2, cytosolic (DH IC-2) (Cytoplasmic
dynein intermediate chain 2)
Length = 612
Score = 251 bits (640), Expect = 9e-67
Identities = 109/164 (66%), Positives = 138/164 (84%)
Frame = +3
Query: 9 WPKHRVVTCLDWSPMYPELLLGAYHCNEEAPHEPDGVCLIWNLKYKKDSPEYVLHCQSPL 188
W KHRVV+CLDWS YPELL+ +Y+ NEEAPHEPDGV L+WN+KYKK +PEYV HCQS +
Sbjct: 250 WSKHRVVSCLDWSSQYPELLVASYNNNEEAPHEPDGVALVWNMKYKKTTPEYVFHCQSAV 309
Query: 189 VSACMPNYHPSLIVGGTYSGQIVLWDIRTNKRTPIQRTPLNATSHTHPVCALTVLGTQNA 368
+SA +HP+L+VGGTYSGQIVLWD R+NKRTP+QRTPL+A +HTHPV + V+GTQNA
Sbjct: 310 MSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNA 369
Query: 369 HNLISVSSDGKMCAWSLEMLNAPSETREFSVKQAKSIAVTCMDF 500
HNLIS+S+DGK+C+WSL+ML+ P ++ E KQ+K++AVT M F
Sbjct: 370 HNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSF 413
>sp|Q62871|DYI2_RAT Dynein intermediate chain 2, cytosolic (DH IC-2) (Cytoplasmic
dynein intermediate chain 2)
Length = 638
Score = 251 bits (640), Expect = 9e-67
Identities = 109/164 (66%), Positives = 138/164 (84%)
Frame = +3
Query: 9 WPKHRVVTCLDWSPMYPELLLGAYHCNEEAPHEPDGVCLIWNLKYKKDSPEYVLHCQSPL 188
W KHRVV+CLDWS YPELL+ +Y+ NEEAPHEPDGV L+WN+KYKK +PEYV HCQS +
Sbjct: 276 WSKHRVVSCLDWSSQYPELLVASYNNNEEAPHEPDGVALVWNMKYKKTTPEYVFHCQSAV 335
Query: 189 VSACMPNYHPSLIVGGTYSGQIVLWDIRTNKRTPIQRTPLNATSHTHPVCALTVLGTQNA 368
+SA +HP+L+VGGTYSGQIVLWD R+NKRTP+QRTPL+A +HTHPV + V+GTQNA
Sbjct: 336 MSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNA 395
Query: 369 HNLISVSSDGKMCAWSLEMLNAPSETREFSVKQAKSIAVTCMDF 500
HNLIS+S+DGK+C+WSL+ML+ P ++ E KQ+K++AVT M F
Sbjct: 396 HNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSF 439
>sp|Q13409|DYI2_HUMAN Dynein intermediate chain 2, cytosolic (DH IC-2) (Cytoplasmic
dynein intermediate chain 2)
Length = 638
Score = 249 bits (637), Expect = 2e-66
Identities = 108/164 (65%), Positives = 138/164 (84%)
Frame = +3
Query: 9 WPKHRVVTCLDWSPMYPELLLGAYHCNEEAPHEPDGVCLIWNLKYKKDSPEYVLHCQSPL 188
W KHRVV+CLDWS YPELL+ +Y+ NE+APHEPDGV L+WN+KYKK +PEYV HCQS +
Sbjct: 276 WSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAV 335
Query: 189 VSACMPNYHPSLIVGGTYSGQIVLWDIRTNKRTPIQRTPLNATSHTHPVCALTVLGTQNA 368
+SA +HP+L+VGGTYSGQIVLWD R+NKRTP+QRTPL+A +HTHPV + V+GTQNA
Sbjct: 336 MSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNA 395
Query: 369 HNLISVSSDGKMCAWSLEMLNAPSETREFSVKQAKSIAVTCMDF 500
HNLIS+S+DGK+C+WSL+ML+ P ++ E KQ+K++AVT M F
Sbjct: 396 HNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSF 439
>sp|O14576|DYI1_HUMAN Dynein intermediate chain 1, cytosolic (DH IC-1) (Cytoplasmic
dynein intermediate chain 1)
Length = 645
Score = 244 bits (623), Expect = 8e-65
Identities = 104/164 (63%), Positives = 136/164 (82%)
Frame = +3
Query: 9 WPKHRVVTCLDWSPMYPELLLGAYHCNEEAPHEPDGVCLIWNLKYKKDSPEYVLHCQSPL 188
W KHRVVTC+DWS YPEL++ +Y+ NE+APHEPDGV L+WN+K+KK +PEYV HCQS +
Sbjct: 284 WSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSV 343
Query: 189 VSACMPNYHPSLIVGGTYSGQIVLWDIRTNKRTPIQRTPLNATSHTHPVCALTVLGTQNA 368
+S C +HP+L+VGGTYSGQIVLWD R+++RTP+QRTPL+A +HTHPV + V+GTQNA
Sbjct: 344 MSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNA 403
Query: 369 HNLISVSSDGKMCAWSLEMLNAPSETREFSVKQAKSIAVTCMDF 500
HNLI+VS+DGKMC+WSL+ML+ P E+ E ++K +AVT M F
Sbjct: 404 HNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAF 447
>sp|Q63100|DYI1_RAT Dynein intermediate chain 1, cytosolic (DH IC-1) (Cytoplasmic
dynein intermediate chain 1)
Length = 643
Score = 243 bits (621), Expect = 1e-64
Identities = 104/164 (63%), Positives = 135/164 (82%)
Frame = +3
Query: 9 WPKHRVVTCLDWSPMYPELLLGAYHCNEEAPHEPDGVCLIWNLKYKKDSPEYVLHCQSPL 188
W KHRVVTC+DWS YPEL++ +Y NE+APHEPDGV L+WN+K+KK +PEYV HCQS +
Sbjct: 282 WSKHRVVTCMDWSLQYPELMVASYSNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSV 341
Query: 189 VSACMPNYHPSLIVGGTYSGQIVLWDIRTNKRTPIQRTPLNATSHTHPVCALTVLGTQNA 368
+S C +HP+L+VGGTYSGQIVLWD R+++RTP+QRTPL+A +HTHPV + V+GTQNA
Sbjct: 342 MSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNA 401
Query: 369 HNLISVSSDGKMCAWSLEMLNAPSETREFSVKQAKSIAVTCMDF 500
HNLI+VS+DGKMC+WSL+ML+ P E+ E ++K +AVT M F
Sbjct: 402 HNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAF 445
>sp|O88485|DYI1_MOUSE Dynein intermediate chain 1, cytosolic (DH IC-1) (Cytoplasmic
dynein intermediate chain 1)
Length = 628
Score = 238 bits (608), Expect = 5e-63
Identities = 102/164 (62%), Positives = 133/164 (81%)
Frame = +3
Query: 9 WPKHRVVTCLDWSPMYPELLLGAYHCNEEAPHEPDGVCLIWNLKYKKDSPEYVLHCQSPL 188
W KHRVVTC+DWS YPEL++ +Y NE+APHEPDGV L+WN+K+KK +PEYV HCQS +
Sbjct: 267 WSKHRVVTCMDWSLQYPELMVASYSNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSV 326
Query: 189 VSACMPNYHPSLIVGGTYSGQIVLWDIRTNKRTPIQRTPLNATSHTHPVCALTVLGTQNA 368
+S C +HP+L+VGGTYSGQIVLWD R+++RTP+QRTPL+A +HTHPV + V+GT NA
Sbjct: 327 MSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTHNA 386
Query: 369 HNLISVSSDGKMCAWSLEMLNAPSETREFSVKQAKSIAVTCMDF 500
NLI+VS+DGKMC+WSL+ML+ P E+ E ++K +AVT M F
Sbjct: 387 RNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAF 430
>sp|Q24246|DYIN_DROME Dynein intermediate chain, cytosolic (DH IC) (Cytoplasmic dynein
intermediate chain) (Short wing protein)
Length = 663
Score = 230 bits (587), Expect = 1e-60
Identities = 99/164 (60%), Positives = 133/164 (81%)
Frame = +3
Query: 9 WPKHRVVTCLDWSPMYPELLLGAYHCNEEAPHEPDGVCLIWNLKYKKDSPEYVLHCQSPL 188
W K+R +T +DWS +PEL++G+YH NEE+P+EPDGV ++WN K+KK +PE V HCQS +
Sbjct: 310 WSKNRCITSMDWSTHFPELVVGSYHNNEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAV 369
Query: 189 VSACMPNYHPSLIVGGTYSGQIVLWDIRTNKRTPIQRTPLNATSHTHPVCALTVLGTQNA 368
+S C ++P+LI+GGTYSGQIVLWD R KRTPIQRTPL+A +HTHPV L ++GTQNA
Sbjct: 370 MSTCFAKFNPNLILGGTYSGQIVLWDNRVQKRTPIQRTPLSAAAHTHPVYCLQMVGTQNA 429
Query: 369 HNLISVSSDGKMCAWSLEMLNAPSETREFSVKQAKSIAVTCMDF 500
HN+IS+SSDGK+C+WSL+ML+ P +T E +Q+K+IA+T M F
Sbjct: 430 HNVISISSDGKLCSWSLDMLSQPQDTLELQQRQSKAIAITSMAF 473
>sp|P54703|DYIN_DICDI Dynein intermediate chain, cytosolic (DH IC) (Cytoplasmic dynein
intermediate chain)
Length = 652
Score = 171 bits (432), Expect = 1e-42
Identities = 73/156 (46%), Positives = 108/156 (69%)
Frame = +3
Query: 9 WPKHRVVTCLDWSPMYPELLLGAYHCNEEAPHEPDGVCLIWNLKYKKDSPEYVLHCQSPL 188
W KHR +T + WS +PEL++ +Y NE H+PDGV L+W++ PEYV CQSP+
Sbjct: 275 WTKHRSITDISWSTKHPELVVSSYSANEAGSHDPDGVALVWSVNNYFQKPEYVFTCQSPV 334
Query: 189 VSACMPNYHPSLIVGGTYSGQIVLWDIRTNKRTPIQRTPLNATSHTHPVCALTVLGTQNA 368
++ +H +LIVGGTYSGQIV+WD R + P+Q+TPL++ HTHPV ++ V+G+ NA
Sbjct: 335 MTTFFSKFHSTLIVGGTYSGQIVIWDTRAEAK-PVQKTPLSSVGHTHPVYSMAVVGSANA 393
Query: 369 HNLISVSSDGKMCAWSLEMLNAPSETREFSVKQAKS 476
++L+S+S+D K+C+W+LE L+ P ET E + S
Sbjct: 394 NSLVSISTDAKLCSWNLENLSQPIETIELNSSNTNS 429
Score = 32.7 bits (73), Expect = 0.50
Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Frame = +3
Query: 111 DGVCLIWNLKYKKDSPEYVLHCQSPLV-SACMPNYHPSLIVGGTYSGQIVLWDIRTNKRT 287
D C +W+ K K++P Y V A HPS+ G SG + LWD+ +
Sbjct: 517 DWTCKLWSSK--KETPLYSFEDYVDYVYDARWSPVHPSIFSTGDGSGTLSLWDLNQDLEG 574
Query: 288 PIQRTPLNATS 320
PI R ++ S
Sbjct: 575 PIFRHKISNRS 585
>sp|Q16960|DYI3_ANTCR Dynein intermediate chain 3, ciliary
Length = 597
Score = 63.9 bits (154), Expect = 2e-10
Identities = 46/146 (31%), Positives = 72/146 (49%), Gaps = 5/146 (3%)
Frame = +3
Query: 21 RVVTCLDWSPMYPELLLGAYHCNE--EAPHEPDGVCLIWNLKYKKDSPEYVLHCQSPLVS 194
R T L W P P+ L AY E + E IW+++ + PE+VL SPLV
Sbjct: 162 RPATHLSWYPDGPKKLAVAYSSLEFQKTSAETSMDSYIWDIE-NPNKPEFVLKPVSPLV- 219
Query: 195 ACMPNYHPS---LIVGGTYSGQIVLWDIRTNKRTPIQRTPLNATSHTHPVCALTVLGTQN 365
C+ Y+P +++GG Y+GQ+ WD R + ++ +P+ SH PV L ++
Sbjct: 220 -CL-EYNPKDVHVLIGGCYNGQVAFWDTRKGSQA-VEMSPVE-HSHHDPVYKTIWLQSKT 275
Query: 366 AHNLISVSSDGKMCAWSLEMLNAPSE 443
S S+DG++ W + L P+E
Sbjct: 276 GTECFSASTDGQVLWWDMRKLGEPTE 301
>sp|Q9GZS0|DYI4_HUMAN Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate
chain 2)
Length = 605
Score = 63.2 bits (152), Expect = 3e-10
Identities = 43/143 (30%), Positives = 64/143 (44%), Gaps = 2/143 (1%)
Frame = +3
Query: 21 RVVTCLDWSPMYPELLLGAYHCNE--EAPHEPDGVCLIWNLKYKKDSPEYVLHCQSPLVS 194
R T L W P L AY C + AP IW+L+ + PE L SPLV+
Sbjct: 163 RAATHLSWHPDGNRKLAVAYSCLDFQRAPVGMSSDSYIWDLE-NPNKPELALKPSSPLVT 221
Query: 195 ACMPNYHPSLIVGGTYSGQIVLWDIRTNKRTPIQRTPLNATSHTHPVCALTVLGTQNAHN 374
+++GG Y+GQI WD T K + + +SH PV L ++
Sbjct: 222 LEFNPKDSHVLLGGCYNGQIACWD--TRKGSLVAELSTIESSHRDPVYGTIWLQSKTGTE 279
Query: 375 LISVSSDGKMCAWSLEMLNAPSE 443
S S+DG++ W + ++ P+E
Sbjct: 280 CFSASTDGQVMWWDIRKMSEPTE 302
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,632,364
Number of Sequences: 369166
Number of extensions: 1198218
Number of successful extensions: 3078
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2918
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3058
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3218280650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)