Planarian EST Database


Dr_sW_028_O18

BLASTX 2.2.12 [Aug-07-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Dr_sW_028_O18
         (759 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q19673|TYR3_CAEEL  Putative tyrosinase-like protein tyr-3...   121   2e-27
sp|Q9QXX0|JAG1_MOUSE  Jagged-1 precursor (Jagged1)                 67   5e-11
sp|P78504|JAG1_HUMAN  Jagged-1 precursor (Jagged1) (hJ1) (CD...    67   5e-11
sp|Q63722|JAG1_RAT  Jagged-1 precursor (Jagged1)                   67   5e-11
sp|Q20191|NAS13_CAEEL  Zinc metalloproteinase nas-13 precurs...    67   7e-11
sp|Q90Y54|JAG1B_BRARE  Jagged-1b precursor (Jagged1b) (Jagged3)    65   2e-10
sp|P34269|TYR1_CAEEL  Putative tyrosinase-like protein tyr-1...    60   6e-09
sp|P21783|NOTCH_XENLA  Neurogenic locus notch protein homolo...    57   4e-08
sp|Q6DI48|DLLA_BRARE  Delta-like protein A precursor (DeltaA...    57   5e-08
sp|Q90Y57|JAG1A_BRARE  Jagged-1a precursor (Jagged1a) (Jagged1)    55   2e-07
>sp|Q19673|TYR3_CAEEL Putative tyrosinase-like protein tyr-3 precursor
          Length = 683

 Score =  121 bits (303), Expect = 2e-27
 Identities = 64/193 (33%), Positives = 85/193 (44%), Gaps = 35/193 (18%)
 Frame = +1

Query: 1    CTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASN 180
            C  W+ +G C+KN  +M   CK SC  C       N N  C + H +C  W+  GEC  N
Sbjct: 469  CGPWSAKGECQKNPVYMNVWCKASCRQCTP---NYNINEECSDRHTNCAMWSRSGECNKN 525

Query: 181  PGYMLVSCKKACNVCGKENK-----------------------------------CADYR 255
            P +M  +C+ +C  CG+                                      C +  
Sbjct: 526  PLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTPCDSPMCYNED 585

Query: 256  KRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPS 435
            + CPI A+ G C S+P +M   CK SCGVC  +    PC D + DCA WA   EC  N  
Sbjct: 586  QCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRPNYVYGPCADYHYDCAAWARRGECLKN-K 644

Query: 436  WMLYNCKKSCNHC 474
            WM  NC++SCN C
Sbjct: 645  WMPENCRRSCNTC 657

 Score =  115 bits (289), Expect = 1e-25
 Identities = 64/212 (30%), Positives = 88/212 (41%), Gaps = 36/212 (16%)
 Frame = +1

Query: 118  NCLNSHESCDTWADRGECASNPGYMLVSCKKACNVC----GKENKCADYRKRCPIMAKYG 285
            +C N +E C  W+ +GEC  NP YM V CK +C  C        +C+D    C + ++ G
Sbjct: 461  SCFNENECCGPWSAKGECQKNPVYMNVWCKASCRQCTPNYNINEECSDRHTNCAMWSRSG 520

Query: 286  LCESDPRFMLQNCKESCGVC---------------------------DGSSKNRP----- 369
             C  +P +M +NC+ SC  C                           +   +N P     
Sbjct: 521  ECNKNPLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTPCDSPM 580

Query: 370  CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWAN 549
            C + +Q C  WA   +C +NP +M   CK SC  CR      +  P C D    C  WA 
Sbjct: 581  CYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRP---NYVYGP-CADYHYDCAAWAR 636

Query: 550  AGECQLNPGWAKQNCPFSCQHCGGCRDLIQNC 645
             GEC  N  W  +NC  SC  C   + L   C
Sbjct: 637  RGECLKNK-WMPENCRRSCNTCVNQQQLAARC 667

 Score =  103 bits (258), Expect = 4e-22
 Identities = 62/203 (30%), Positives = 89/203 (43%), Gaps = 35/203 (17%)
 Frame = +1

Query: 223  CGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK-NRPCVDANQDCAG 399
            C  EN+C      C   +  G C+ +P +M   CK SC  C  +   N  C D + +CA 
Sbjct: 462  CFNENEC------CGPWSAKGECQKNPVYMNVWCKASCRQCTPNYNINEECSDRHTNCAM 515

Query: 400  WAASHECETNPSWMLYNCKKSCNHCRDAR---------LESISDPN-------------- 510
            W+ S EC  NP WM  NC+ SC  C  +R          +SIS+P               
Sbjct: 516  WSRSGECNKNPLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTP 575

Query: 511  -----CKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC------GGCRDLIQNCQNFA 657
                 C +    C  WA  G+C+ NPG+    C  SC  C      G C D   +C  +A
Sbjct: 576  CDSPMCYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRPNYVYGPCADYHYDCAAWA 635

Query: 658  NQGYCKTNEVYMNQSCKKTCGFC 726
             +G C  N+ +M ++C+++C  C
Sbjct: 636  RRGECLKNK-WMPENCRRSCNTC 657
>sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1)
          Length = 1218

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 67/296 (22%), Positives = 108/296 (36%), Gaps = 54/296 (18%)
 Frame = +1

Query: 4    TKWAREGLCEKNFNFM--QKNCKFSCDACQDIGDGDN--------SNPNCLNSHESC--D 147
            T W  + LC+K+ N+    + C  +   C + G            S PNC  +  +C  D
Sbjct: 286  TNWGGQ-LCDKDLNYCGTHQPC-LNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSD 343

Query: 148  TWADRG---------ECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESD 300
               +RG         EC  +PG+   +C    + C   N    +   C  +     C   
Sbjct: 344  PCHNRGSCKETSSGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCP 401

Query: 301  PRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRD 480
            P++  + C+     C+     +PCV+A + C    AS+ C+  P WM  NC  + N C  
Sbjct: 402  PQWTGKTCQLDANECEA----KPCVNA-RSCKNLIASYYCDCLPGWMGQNCDININDCLG 456

Query: 481  ARLESISDPNCKDLQI-------------------------------HCLYWANAGECQL 567
               +  +D +C+DL                                 HC    N  +C  
Sbjct: 457  ---QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLC 513

Query: 568  NPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 729
              G++   C     +C    C++  Q C N A+  +CK  E Y  ++C      CR
Sbjct: 514  PTGFSGNLCQLDIDYCEPNPCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCR 568

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 49/244 (20%), Positives = 81/244 (33%), Gaps = 9/244 (3%)
 Frame = +1

Query: 1    CTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASN 180
            C   A +  C+   ++  KNC    D C+                +SC       +    
Sbjct: 540  CYNRASDYFCKCPEDYEGKNCSHLKDHCRT---------TTCEVIDSCTVAMASNDTPEG 590

Query: 181  PGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK 360
              Y+      + NVCG   KC           K+  C+ +  F    C E+   C+ +  
Sbjct: 591  VRYI------SSNVCGPHGKCKSQSG-----GKF-TCDCNKGFTGTYCHENINDCESN-- 636

Query: 361  NRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLY 540
              PC +    C     S++C  +  W   +C+ + N C  ++        C+DL      
Sbjct: 637  --PCKNGGT-CIDGVNSYKCICSDGWEGAHCENNINDC--SQNPCHYGGTCRDL------ 685

Query: 541  WANAGECQLNPGWAKQNC--------PFSCQHCGGCRDLIQNCQNFANQGYCKTN-EVYM 693
              N   C    GW  + C          +C + G C D +   +     G+  T   +  
Sbjct: 686  -VNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEVDTFKCMCPGGWEGTTCNIAR 744

Query: 694  NQSC 705
            N SC
Sbjct: 745  NSSC 748

 Score = 33.5 bits (75), Expect = 0.64
 Identities = 34/166 (20%), Positives = 57/166 (34%), Gaps = 9/166 (5%)
 Frame = +1

Query: 28  CEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCK 207
           C+    +M +NC  + + C      D S  + +N +           C   PGY    C+
Sbjct: 436 CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR----------CICPPGYAGDHCE 485

Query: 208 KACNVCGK---------ENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK 360
           +  + C           +N+   ++  CP      LC+ D  +   N             
Sbjct: 486 RDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPN------------- 532

Query: 361 NRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESI 498
             PC +  Q C   A+ + C+    +   NC    +HCR    E I
Sbjct: 533 --PCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCRTTTCEVI 575
>sp|P78504|JAG1_HUMAN Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen)
          Length = 1218

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 67/296 (22%), Positives = 108/296 (36%), Gaps = 54/296 (18%)
 Frame = +1

Query: 4    TKWAREGLCEKNFNFM--QKNCKFSCDACQDIGDGDN--------SNPNCLNSHESC--D 147
            T W  + LC+K+ N+    + C  +   C + G            S PNC  +  +C  D
Sbjct: 286  TNWGGQ-LCDKDLNYCGTHQPC-LNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSD 343

Query: 148  TWADRG---------ECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESD 300
               +RG         EC  +PG+   +C    + C   N    +   C  +     C   
Sbjct: 344  PCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCP 401

Query: 301  PRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRD 480
            P++  + C+     C+     +PCV+A + C    AS+ C+  P WM  NC  + N C  
Sbjct: 402  PQWTGKTCQLDANECEA----KPCVNA-KSCKNLIASYYCDCLPGWMGQNCDININDCLG 456

Query: 481  ARLESISDPNCKDLQI-------------------------------HCLYWANAGECQL 567
               +  +D +C+DL                                 HC    N  +C  
Sbjct: 457  ---QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLC 513

Query: 568  NPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 729
              G++   C     +C    C++  Q C N A+  +CK  E Y  ++C      CR
Sbjct: 514  PTGFSGNLCQLDIDYCEPNPCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCR 568

 Score = 33.5 bits (75), Expect = 0.64
 Identities = 54/274 (19%), Positives = 94/274 (34%), Gaps = 40/274 (14%)
 Frame = +1

Query: 28   CEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCK 207
            C+    +M +NC  + + C      D S  + +N +           C   PGY    C+
Sbjct: 436  CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR----------CICPPGYAGDHCE 485

Query: 208  KACNVCGK---------ENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK 360
            +  + C           +N+   ++  CP      LC+ D  +   N             
Sbjct: 486  RDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPN------------- 532

Query: 361  NRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESI--------SDPNCK 516
              PC +  Q C   A+ + C+    +   NC    +HCR    E I        S+   +
Sbjct: 533  --PCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPE 589

Query: 517  DLQI--------HCLYWANAG---ECQLNPGWAKQNCPFS--------CQHCGGCRDLIQ 639
             ++         H    + +G    C  N G+    C  +        C++ G C D + 
Sbjct: 590  GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN 649

Query: 640  NCQNFANQG----YCKTNEVYMNQSCKKTCGFCR 729
            + +   + G    YC+TN    +Q+     G CR
Sbjct: 650  SYKCICSDGWEGAYCETNINDCSQNPCHNGGTCR 683
>sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1)
          Length = 1219

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 67/296 (22%), Positives = 108/296 (36%), Gaps = 54/296 (18%)
 Frame = +1

Query: 4    TKWAREGLCEKNFNFM--QKNCKFSCDACQDIGDGDN--------SNPNCLNSHESC--D 147
            T W  + LC+K+ N+    + C  +   C + G            S PNC  +  +C  D
Sbjct: 286  TNWGGQ-LCDKDLNYCGTHQPC-LNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSD 343

Query: 148  TWADRG---------ECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESD 300
               +RG         EC  +PG+   +C    + C   N    +   C  +     C   
Sbjct: 344  PCHNRGSCKETSSGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCP 401

Query: 301  PRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRD 480
            P++  + C+     C+     +PCV+A + C    AS+ C+  P WM  NC  + N C  
Sbjct: 402  PQWTGKTCQLDANECEA----KPCVNA-RSCKNLIASYYCDCLPGWMGQNCDININDCLG 456

Query: 481  ARLESISDPNCKDLQI-------------------------------HCLYWANAGECQL 567
               +  +D +C+DL                                 HC    N  +C  
Sbjct: 457  ---QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLC 513

Query: 568  NPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 729
              G++   C     +C    C++  Q C N A+  +CK  E Y  ++C      CR
Sbjct: 514  PTGFSGNLCQLDIDYCEPNPCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCR 568

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 59/270 (21%), Positives = 92/270 (34%), Gaps = 42/270 (15%)
 Frame = +1

Query: 22   GLCEKNFNFMQKNCK--FSCDACQDIGDGDNSNPNCLNSHESCDTWAD------------ 159
            G C+   N  Q  C   FS + CQ   D    NP C N  +  +  +D            
Sbjct: 500  GHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNP-CQNGAQCYNRASDYFCKCPEDYEGK 558

Query: 160  -----RGECASNPGYMLVSCKKAC--------------NVCGKENKCADYRKRCPIMAKY 282
                 +  C + P  ++ SC  A               NVCG   KC     +     K+
Sbjct: 559  NCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKC-----KSESGGKF 613

Query: 283  GLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKS 462
              C+ +  F    C E+   C+G+    PC +    C     S++C  +  W   +C+ +
Sbjct: 614  -TCDCNKGFTGTYCHENINDCEGN----PCTNGGT-CIDGVNSYKCICSDGWEGAHCENN 667

Query: 463  CNHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNC--------PFSCQHCG 618
             N C  ++        C+DL        N   C    GW  + C          +C + G
Sbjct: 668  INDC--SQNPCHYGGTCRDL-------VNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGG 718

Query: 619  GCRDLIQNCQNFANQGYCKTN-EVYMNQSC 705
             C D +   +     G+  T   +  N SC
Sbjct: 719  TCYDEVDTFKCMCPGGWEGTTCNIARNSSC 748

 Score = 33.1 bits (74), Expect = 0.83
 Identities = 34/166 (20%), Positives = 57/166 (34%), Gaps = 9/166 (5%)
 Frame = +1

Query: 28  CEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCK 207
           C+    +M +NC  + + C      D S  + +N +           C   PGY    C+
Sbjct: 436 CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR----------CICPPGYAGDHCE 485

Query: 208 KACNVCGK---------ENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK 360
           +  + C           +N+   ++  CP      LC+ D  +   N             
Sbjct: 486 RDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPN------------- 532

Query: 361 NRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESI 498
             PC +  Q C   A+ + C+    +   NC    +HCR    E I
Sbjct: 533 --PCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVI 575
>sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precursor (Nematode astacin 13)
          Length = 527

 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
 Frame = +1

Query: 238 KCADYRKRCPIMAKYGLCES--DPRFMLQNCKESCGVCDGSSKNRP-CVDANQDCAGWAA 408
           KC D RK C  +A+ G CES    RFM +NC  SCG C    K +  C DA   C  WA 
Sbjct: 444 KCEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWAN 503

Query: 409 SHECETN--PSWMLYNCKKSCNHC 474
           S  C       +M   C KSCN C
Sbjct: 504 SGMCNQTVFKDYMRQKCAKSCNFC 527

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 11/83 (13%)
 Frame = +1

Query: 511 CKDLQIHCLYWANAGECQ--LNPGWAKQNCPFSCQHCGG-------CRDLIQNCQNFANQ 663
           C+D +  C + A AG C+   +  +  +NC  SC  C         C D    C+ +AN 
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWANS 504

Query: 664 GYCKTN--EVYMNQSCKKTCGFC 726
           G C     + YM Q C K+C FC
Sbjct: 505 GMCNQTVFKDYMRQKCAKSCNFC 527

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
 Frame = +1

Query: 1   CTKWAREGLCEKNFN--FMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECA 174
           C   AR G CE  F+  FM +NC  SC  C  I + +     C ++   C+ WA+ G C 
Sbjct: 452 CEFLARAGHCESRFSIRFMTENCANSCGKC--IAE-EKRKEVCEDARTWCERWANSGMCN 508

Query: 175 SN--PGYMLVSCKKACNVC 225
                 YM   C K+CN C
Sbjct: 509 QTVFKDYMRQKCAKSCNFC 527

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
 Frame = +1

Query: 370 CVDANQDCAGWAASHECETNPS--WMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYW 543
           C D  +DC   A +  CE+  S  +M  NC  SC  C     E      C+D +  C  W
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCI---AEEKRKEVCEDARTWCERW 501

Query: 544 ANAGECQ--LNPGWAKQNCPFSCQHC 615
           AN+G C   +   + +Q C  SC  C
Sbjct: 502 ANSGMCNQTVFKDYMRQKCAKSCNFC 527

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 8/83 (9%)
 Frame = +1

Query: 121 CLNSHESCDTWADRGECASNPG--YMLVSCKKACNVCGKENK----CADYRKRCPIMAKY 282
           C +  + C+  A  G C S     +M  +C  +C  C  E K    C D R  C   A  
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWANS 504

Query: 283 GLCESD--PRFMLQNCKESCGVC 345
           G+C       +M Q C +SC  C
Sbjct: 505 GMCNQTVFKDYMRQKCAKSCNFC 527

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
 Frame = +1

Query: 616 GGCRDLIQNCQNFANQGYCKT--NEVYMNQSCKKTCGFC 726
           G C D  ++C+  A  G+C++  +  +M ++C  +CG C
Sbjct: 443 GKCEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKC 481
>sp|Q90Y54|JAG1B_BRARE Jagged-1b precursor (Jagged1b) (Jagged3)
          Length = 1213

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 61/280 (21%), Positives = 99/280 (35%), Gaps = 38/280 (13%)
 Frame = +1

Query: 4    TKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNP 183
            T W  + LC+K+ N+                    ++  CLN     +T  D+ +C+   
Sbjct: 283  TNWGGQ-LCDKDLNYC------------------GTHQPCLNGGTCSNTGPDKYQCSCED 323

Query: 184  GYMLVSCKKACNVCGKENKCAD----------YRKRC-----------------PIMAKY 282
            GY  V+C++A + C   N CA+          Y   C                 P   K+
Sbjct: 324  GYSGVNCERAEHAC-LSNPCANGGTCKETSQGYECHCAIGWSGTSCEINVDDCTPNQCKH 382

Query: 283  G----------LCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNP 432
            G           C   P +  + C+     C+    ++PCV+A + C     ++ CE  P
Sbjct: 383  GGTCQDLVNGFKCACPPHWTGKTCQIDANECE----DKPCVNA-KSCHNLIGAYFCECLP 437

Query: 433  SWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQH 612
             W   NC  + N C+    + ++   CKDL        N   C   PG+  + C      
Sbjct: 438  GWSGQNCDININDCKG---QCLNGGTCKDL-------VNGYRCLCPPGYTGEQCEKDVDE 487

Query: 613  CGGCRDLI-QNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 729
            C     L    CQ+  N   C     +  Q C+    +C+
Sbjct: 488  CASSPCLNGGRCQDEVNGFQCLCPAGFSGQLCQLDIDYCK 527

 Score = 34.7 bits (78), Expect = 0.29
 Identities = 53/285 (18%), Positives = 87/285 (30%), Gaps = 52/285 (18%)
 Frame = +1

Query: 28   CEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCK 207
            CE    +  +NC  + + C+           CLN   +C    +   C   PGY    C+
Sbjct: 433  CECLPGWSGQNCDININDCKG---------QCLNGG-TCKDLVNGYRCLCPPGYTGEQCE 482

Query: 208  KACNVCGKE-----NKCAD----YRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK 360
            K  + C         +C D    ++  CP      LC+ D  +   N  ++   C   + 
Sbjct: 483  KDVDECASSPCLNGGRCQDEVNGFQCLCPAGFSGQLCQLDIDYCKPNPCQNGAQCFNLAS 542

Query: 361  NRPCVDANQDCAGWAASH---ECETN-----------------PSWMLYNCKKSCN---- 468
            +  C     D  G   SH    C T                  P  + Y     C     
Sbjct: 543  DYFC-KCPDDYEGKNCSHLKDHCRTTSCQVIDSCTVAVASNSTPEGVRYISSNVCGPHGR 601

Query: 469  -----------HCRDARLESISDPNCKDLQIH-------CLYWANAGECQLNPGWAKQNC 594
                        C++    +    N  D + +       C+   N  +C    GW   +C
Sbjct: 602  CRSQAGGQFTCECQEGFRGTYCHENINDCESNPCRNGGTCIDKVNVYQCICADGWEGVHC 661

Query: 595  PFSCQHCGGCRDLIQN-CQNFANQGYCKTNEVYMNQSCKKTCGFC 726
              +   C     L +  CQ+  N  YC+    +  ++C      C
Sbjct: 662  EINIDDCSLNPCLNKGACQDLVNDFYCECRNGWKGKTCHSRDSQC 706

 Score = 33.5 bits (75), Expect = 0.64
 Identities = 31/161 (19%), Positives = 54/161 (33%)
 Frame = +1

Query: 1    CTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASN 180
            C     +  CE    +  K C      C +            N+  +C    D  +C  +
Sbjct: 679  CQDLVNDFYCECRNGWKGKTCHSRDSQCDEA---------TCNNGGTCHDEGDTFKCRCS 729

Query: 181  PGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK 360
            PG+   +C  A N     N C +    C +      C     +    C E+   C+    
Sbjct: 730  PGWEGATCNIAKNSSCLPNPC-ENGGTCVVNGDSFNCVCKEGWEGSTCTENTNDCN---- 784

Query: 361  NRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDA 483
              PC ++   C      + CE  P +   +C+ + N C+ +
Sbjct: 785  PHPCYNSG-TCVDGENWYRCECAPGFAGPDCRININECQSS 824
>sp|P34269|TYR1_CAEEL Putative tyrosinase-like protein tyr-1 precursor
          Length = 601

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 23/81 (28%), Positives = 40/81 (49%)
 Frame = +1

Query: 232 ENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAAS 411
           ++ C +    C   ++   C ++  +M + C++SCG+C  +  NR C D +  CA W   
Sbjct: 477 QSNCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQ 536

Query: 412 HECETNPSWMLYNCKKSCNHC 474
           + C     WM  NC+ +C  C
Sbjct: 537 NFCTRRRQWMAENCQATCGWC 557

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 29/98 (29%), Positives = 43/98 (43%)
 Frame = +1

Query: 370 CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWAN 549
           C + +  C  W+  +EC TN  +M   C+KSC  C+     + ++  C D  I C YW  
Sbjct: 480 CYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQ----SNDNNRGCHDRHISCAYWRG 535

Query: 550 AGECQLNPGWAKQNCPFSCQHCGGCRDLIQNCQNFANQ 663
              C     W  +NC  +C  C    +  Q C + A Q
Sbjct: 536 QNFCTRRRQWMAENCQATCGWCN--MNEAQLCASVARQ 571

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
 Frame = +1

Query: 118 NCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENK---CADYRKRCPIMAKYGL 288
           NC N    C+ W+ + EC +N  YM   C+K+C +C   +    C D    C        
Sbjct: 479 NCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQNF 538

Query: 289 CESDPRFMLQNCKESCGVCD 348
           C    ++M +NC+ +CG C+
Sbjct: 539 CTRRRQWMAENCQATCGWCN 558

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 5/105 (4%)
 Frame = +1

Query: 1   CTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASN 180
           C +W+R+  C  N  +M + C+ SC  CQ     +++N  C + H SC  W  +  C   
Sbjct: 487 CNQWSRQNECRTNTVYMNRYCRKSCGLCQ----SNDNNRGCHDRHISCAYWRGQNFCTRR 542

Query: 181 PGYMLVSCKKACNVCGKEN-----KCADYRKRCPIMAKYGLCESD 300
             +M  +C+  C  C           A   +R    AK+ L E D
Sbjct: 543 RQWMAENCQATCGWCNMNEAQLCASVARQSRRVRRNAKFWLTEPD 587

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
 Frame = +1

Query: 508 NCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHCG------GCRDLIQNCQNFANQGY 669
           NC +    C  W+   EC+ N  +  + C  SC  C       GC D   +C  +  Q +
Sbjct: 479 NCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQNF 538

Query: 670 CKTNEVYMNQSCKKTCGFC 726
           C     +M ++C+ TCG+C
Sbjct: 539 CTRRRQWMAENCQATCGWC 557

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 14/29 (48%), Positives = 21/29 (72%)
 Frame = +1

Query: 643 CQNFANQGYCKTNEVYMNQSCKKTCGFCR 729
           C  ++ Q  C+TN VYMN+ C+K+CG C+
Sbjct: 487 CNQWSRQNECRTNTVYMNRYCRKSCGLCQ 515
>sp|P21783|NOTCH_XENLA Neurogenic locus notch protein homolog precursor (XOTCH protein)
          Length = 2524

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 58/242 (23%), Positives = 91/242 (37%), Gaps = 7/242 (2%)
 Frame = +1

Query: 22  GLCEKNFNFMQKNCK----FSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGY 189
           G CE   +  +  C+    ++ D+CQ   D   SNP C N  + C  +  +  C   PG+
Sbjct: 115 GTCELLNSVTEYKCRCPPGWTGDSCQQ-ADPCASNP-CANGGK-CLPFEIQYICKCPPGF 171

Query: 190 MLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRP 369
              +CK+  N C  +N C +  +       Y  C    RF  +NC E    C+ S    P
Sbjct: 172 HGATCKQDINECS-QNPCKNGGQCINEFGSYR-CTCQNRFTGRNCDEPYVPCNPS----P 225

Query: 370 CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWAN 549
           C++          S++C   P +   NC+++ + C           NC++    C+   N
Sbjct: 226 CLNGGTCRQTDDTSYDCTCLPGFSGQNCEENIDDC--------PSNNCRNGGT-CVDGVN 276

Query: 550 AGECQLNPGWAKQNCPFSCQHCGGCRDLIQN---CQNFANQGYCKTNEVYMNQSCKKTCG 720
              CQ  P W  Q C      C    +  QN   C N      C     +  + C +   
Sbjct: 277 TYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENID 336

Query: 721 FC 726
            C
Sbjct: 337 DC 338

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 46/210 (21%), Positives = 77/210 (36%), Gaps = 2/210 (0%)
 Frame = +1

Query: 106  NSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYG 285
            NSNP C+  H +C    +  +C    G+   +C    N C + N C +    C  M    
Sbjct: 720  NSNP-CI--HGACHDGVNGYKCDCEAGWSGSNCDINNNEC-ESNPCMN-GGTCKDMTGAY 774

Query: 286  LCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSC 465
            +C     F   NC+ +   C  +    PC++ +  C    A ++C     +    C+   
Sbjct: 775  ICTCKAGFSGPNCQTNINECSSN----PCLN-HGTCIDDVAGYKCNCMLPYTGAICEAVL 829

Query: 466  NHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHCGG--CRDLIQ 639
              C  +  ++     CK+ +    +      C+  PGW  Q C      C    CR+   
Sbjct: 830  APCAGSPCKN--GGRCKESEDFETF-----SCECPPGWQGQTCEIDMNECVNRPCRN-GA 881

Query: 640  NCQNFANQGYCKTNEVYMNQSCKKTCGFCR 729
             CQN      C     Y  ++C+     C+
Sbjct: 882  TCQNTNGSYKCNCKPGYTGRNCEMDIDDCQ 911

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 53/224 (23%), Positives = 78/224 (34%), Gaps = 3/224 (1%)
 Frame = +1

Query: 28   CEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCK 207
            C     +  +NC+   D CQ         PN  ++  SC    +   C    G+    C+
Sbjct: 892  CNCKPGYTGRNCEMDIDDCQ---------PNPCHNGGSCSDGINMFFCNCPAGFRGPKCE 942

Query: 208  KACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQ 387
            +  N C   N C +    C        C   P F   +C+ +   C  SS    C +   
Sbjct: 943  EDINECA-SNPCKN-GANCTDCVNSYTCTCQPGFSGIHCESNTPDCTESS----CFNGG- 995

Query: 388  DCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANAGECQL 567
             C     +  C+  P +    C+   N C        S P        CL   N G CQ 
Sbjct: 996  TCIDGINTFTCQCPPGFTGSYCQHDINECD-------SKP--------CL---NGGTCQD 1037

Query: 568  NPGWAKQNCPFSCQHCGGCRDLIQNCQN--FANQGYC-KTNEVY 690
            + G  K  CP        C++L++ C +    N G C +TN  Y
Sbjct: 1038 SYGTYKCTCPQGYTGL-NCQNLVRWCDSSPCKNGGKCWQTNNFY 1080

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 63/248 (25%), Positives = 80/248 (32%), Gaps = 31/248 (12%)
 Frame = +1

Query: 58   NCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCK---KAC--NV 222
            NC+   D C        SN   L  +  C    D  EC   PGY    C      C  N 
Sbjct: 636  NCETKIDDCA-------SN---LCDNGKCIDKIDGYECTCEPGYTGKLCNININECDSNP 685

Query: 223  CGKENKCAD----YRKRCPIMAKYGLCESDPRFMLQNCKES-C--GVCDGSSKNRPCVDA 381
            C     C D    +   CP      +C S+    +  C  + C  G C        C   
Sbjct: 686  CRNGGTCKDQINGFTCVCPDGYHDHMCLSE----VNECNSNPCIHGACHDGVNGYKC--- 738

Query: 382  NQDC-AGWAAS------HECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLY 540
              DC AGW+ S      +ECE+NP      CK              S PNC+        
Sbjct: 739  --DCEAGWSGSNCDINNNECESNPCMNGGTCKDMTGAYICTCKAGFSGPNCQ-------- 788

Query: 541  WANAGECQLNP---------GWAKQNCPFSCQHCGG-CRDLIQNCQN--FANQGYCKTNE 684
              N  EC  NP           A   C     + G  C  ++  C      N G CK +E
Sbjct: 789  -TNINECSSNPCLNHGTCIDDVAGYKCNCMLPYTGAICEAVLAPCAGSPCKNGGRCKESE 847

Query: 685  VYMNQSCK 708
             +   SC+
Sbjct: 848  DFETFSCE 855

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 45/216 (20%), Positives = 72/216 (33%), Gaps = 13/216 (6%)
 Frame = +1

Query: 22   GLCEK--NFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYML 195
            G+C    N +F +    ++   C++    D  +PN   +  +C  +     C    GY  
Sbjct: 1119 GMCVDTGNTHFCRCQAGYTGSYCEE--QVDECSPNPCQNGATCTDYLGGYSCECVAGYHG 1176

Query: 196  VSCKKACN-----VCGKENKCAD----YRKRCPIMAKYGLCESDPRFMLQNCKESCGVCD 348
            V+C +  N      C     C D    Y+  CP   +   CE        N  +     D
Sbjct: 1177 VNCSEEINECLSHPCQNGGTCIDLINTYKCSCPRGTQGVHCEI-------NVDDCTPFYD 1229

Query: 349  GSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQI 528
              +    C + N  C      + C   P ++   C+   N C     +S    NC  L  
Sbjct: 1230 SFTLEPKCFN-NGKCIDRVGGYNCICPPGFVGERCEGDVNECLSNPCDSRGTQNCIQL-- 1286

Query: 529  HCLYWANAGECQLNPGWAKQNCPFSCQHCGG--CRD 630
                  N   C+   G+  + C      C G  CR+
Sbjct: 1287 -----VNDYRCECRQGFTGRRCESVVDGCKGMPCRN 1317

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 59/240 (24%), Positives = 84/240 (35%), Gaps = 37/240 (15%)
 Frame = +1

Query: 109  SNPNCLNSHESCDTWADRGE--CASNPGYM-------LVSCKKACNVCGKENKCAD---- 249
            SNP   N   +CDT    G+  C   PGY        +  C    N C    +C +    
Sbjct: 377  SNP--CNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSLGANPCEHGGRCTNTLGS 434

Query: 250  YRKRCPIMAKYGLCESDPRFMLQN-------CKESCG----VCDGSSKNRPCVDANQDCA 396
            ++  CP       CE D    L N       C +  G    +C    +   C     +CA
Sbjct: 435  FQCNCPQGYAGPRCEIDVNECLSNPCQNDSTCLDQIGEFQCICMPGYEGLYCETNIDECA 494

Query: 397  GWAASH--ECETNPSWMLYNCKK--SCNHCRDARLESISDPNCKDLQIHCLYWANAGECQ 564
                 H  +C    +    +C    S N C+    E  S P CK+    CL   N+  CQ
Sbjct: 495  SNPCLHNGKCIDKINEFRCDCPTGFSGNLCQHDFDECTSTP-CKN-GAKCLDGPNSYTCQ 552

Query: 565  LNPGWAKQNC--------PFSCQHCGGCRDLIQNCQNFANQGYC-KTNEVYMNQSCKKTC 717
               G+  ++C        P  C H G C+D I         GY  +  +  +N+   K C
Sbjct: 553  CTEGFTGRHCEQDINECIPDPC-HYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSKPC 611

 Score = 37.4 bits (85), Expect = 0.044
 Identities = 60/277 (21%), Positives = 93/277 (33%), Gaps = 45/277 (16%)
 Frame = +1

Query: 22  GLCEKNFNFMQKNC--KFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYML 195
           G C   F   +  C  +F+   C +     N +P CLN      T     +C   PG+  
Sbjct: 192 GQCINEFGSYRCTCQNRFTGRNCDEPYVPCNPSP-CLNGGTCRQTDDTSYDCTCLPGFSG 250

Query: 196 VSCKKACNVCGKEN-----KCAD----YRKRCPI--MAKYGLCESDPRFMLQNCKESCGV 342
            +C++  + C   N      C D    Y  +CP     +Y   + D   ++ N  ++ G 
Sbjct: 251 QNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGT 310

Query: 343 CDGSSKNRPCVDAN-----------QDCAGWAASHECETNPSWMLYNCKKSCNHCRDARL 489
           C  +     CV  N            DCA  A       +     + C+  C H R   L
Sbjct: 311 CHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFYCE--CPHGRTGLL 368

Query: 490 -----ESISDP-----NCKDLQIHCLYWANAGECQLNPGWAKQNCPFS----------CQ 609
                  IS+P     NC    ++         C   PG+    C             C+
Sbjct: 369 CHLDNACISNPCNEGSNCDTNPVN-----GKAICTCPPGYTGPACNNDVDECSLGANPCE 423

Query: 610 HCGGCRDLIQNCQNFANQGYCKTN-EVYMNQSCKKTC 717
           H G C + + + Q    QGY     E+ +N+     C
Sbjct: 424 HGGRCTNTLGSFQCNCPQGYAGPRCEIDVNECLSNPC 460
>sp|Q6DI48|DLLA_BRARE Delta-like protein A precursor (DeltaA protein)
          Length = 772

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 54/224 (24%), Positives = 81/224 (36%), Gaps = 9/224 (4%)
 Frame = +1

Query: 85  QDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRC 264
           QD+    +  P CLN     +T      C+  PG+   SC+   N C   N C +    C
Sbjct: 289 QDLNYCTHHKP-CLNGATCSNTGQGSYTCSCRPGFSGASCEIEVNEC-TGNPCRN-GGSC 345

Query: 265 PIMAKYGLCESDPRFMLQNCKESCGVC-DGSSKNRPCVDANQDCAGWAASHECETNPSWM 441
             M     C   P F  +NC+ S   C DG     PC +  +        + C+    + 
Sbjct: 346 TDMENTYSCTCPPGFYGKNCELSAMTCADG-----PCFNGGRCADNPDGGYFCQCPTGYA 400

Query: 442 LYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNCP-------- 597
            +NC+K  +HC        S   C +    C+   N+  CQ   G+   NC         
Sbjct: 401 GFNCEKKIDHC--------SSSPCSN-GARCVDLVNSYLCQCPDGFTGMNCDRAGDECSM 451

Query: 598 FSCQHCGGCRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 729
           + CQ+ G        CQ  A+   C     Y  ++C      C+
Sbjct: 452 YPCQNGG-------TCQEGASGYMCTCPPGYTGRNCSSPVSRCQ 488

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 37/159 (23%), Positives = 53/159 (33%)
 Frame = +1

Query: 1   CTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASN 180
           CT       C     F  KNC+ S   C D          C N     D       C   
Sbjct: 345 CTDMENTYSCTCPPGFYGKNCELSAMTCAD--------GPCFNGGRCADNPDGGYFCQCP 396

Query: 181 PGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK 360
            GY   +C+K  + C   + C++   RC  +    LC+    F   NC  +   C     
Sbjct: 397 TGYAGFNCEKKIDHC-SSSPCSN-GARCVDLVNSYLCQCPDGFTGMNCDRAGDEC----S 450

Query: 361 NRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCR 477
             PC +    C   A+ + C   P +   NC    + C+
Sbjct: 451 MYPCQNGG-TCQEGASGYMCTCPPGYTGRNCSSPVSRCQ 488
>sp|Q90Y57|JAG1A_BRARE Jagged-1a precursor (Jagged1a) (Jagged1)
          Length = 1242

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 71/310 (22%), Positives = 106/310 (34%), Gaps = 69/310 (22%)
 Frame = +1

Query: 4    TKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNP 183
            T W  + LC+K+ N        +C   Q           CLN     +T  D+  CA   
Sbjct: 287  TNWGGQ-LCDKDLN--------TCGTLQP----------CLNGGTCSNTGPDKYHCACPD 327

Query: 184  GYMLVSCKKACNVC----------------GKENKCA--------------------DYR 255
            GY   +C++A N C                G E +CA                    ++ 
Sbjct: 328  GYSGQNCERADNACLSEPCLNGGLCVESSLGFECQCAAGWTGPSCNINEDDCSPNPCNHS 387

Query: 256  KRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPS 435
              C  +     C    ++  + C      C+ S    PCV+A+  C      + CE  P 
Sbjct: 388  GVCVDLVDGFKCICPVQWTGKTCLIDANECEES----PCVNAH-SCRNLIGGYFCECLPG 442

Query: 436  WMLYNCKKSCNHCRDARLESISDPNCKDL--QIHCLYWA--------------------N 549
            W   NC  + N C     + ++   CKDL     C+  A                    N
Sbjct: 443  WTGQNCDINVNDCHG---QCLNGGLCKDLVNGYRCVCAAGFAGDRCERDVDECASRPCLN 499

Query: 550  AGECQ--LN-------PGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMN 696
             G CQ  LN       PG++   C     +C  G C++  Q C + A+  YCK  E Y  
Sbjct: 500  GGRCQDTLNGFQCLCPPGFSGATCQLDLDYCESGPCQNGAQ-CFSLASDYYCKCPEDYEG 558

Query: 697  QSCKKTCGFC 726
            ++C +    C
Sbjct: 559  KNCSQLKDHC 568

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 56/248 (22%), Positives = 89/248 (35%), Gaps = 20/248 (8%)
 Frame = +1

Query: 22   GLCEKNFNFMQKNCK--FSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYML 195
            GLC+   N  +  C   F+ D C+   D   S P CLN     DT  +  +C   PG+  
Sbjct: 463  GLCKDLVNGYRCVCAAGFAGDRCERDVDECASRP-CLNGGRCQDT-LNGFQCLCPPGFSG 520

Query: 196  VSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNC---KESCGV--CDGSSK 360
             +C+   + C  E+       +C  +A    C+    +  +NC   K+ C +  C     
Sbjct: 521  ATCQLDLDYC--ESGPCQNGAQCFSLASDYYCKCPEDYEGKNCSQLKDHCLITPCQVIDS 578

Query: 361  NRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNH----CRDARLESISDPNCKDLQI 528
                V +N    G          P     +   +  H    C+D    +    N  D + 
Sbjct: 579  CTVAVVSNSTPGGLRLISSSVCGPHGRCRSHSHAGGHFSCDCQDGFTGTYCHENINDCES 638

Query: 529  H-------CLYWANAGECQLNPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTN 681
                    C+   NA +C    GW   NC  +   C    CRD    C++  N  YC+  
Sbjct: 639  SPCLSGGTCIDKINAYQCICADGWEGPNCETNIDDCRTNPCRDR-GVCRDLVNDFYCECE 697

Query: 682  EVYMNQSC 705
              +  ++C
Sbjct: 698  NGWKGKTC 705

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 29/161 (18%), Positives = 55/161 (34%)
 Frame = +1

Query: 1    CTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASN 180
            C     +  CE    +  K C      C +         +  N+  +C    D  +C  +
Sbjct: 685  CRDLVNDFYCECENGWKGKTCHSRESQCDE---------DTCNNGGTCSDEGDSFKCLCS 735

Query: 181  PGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK 360
            PG+   +C  A N     N C +    C +      C     +    C ++   C+    
Sbjct: 736  PGWEGATCNIAKNSSCLPNPC-ENGATCVVTGDGFTCVCKEGWEGPTCSQNSNDCN---- 790

Query: 361  NRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDA 483
             +PC ++   C      + CE    +   +C+ + N C+ +
Sbjct: 791  PQPCYNSG-TCVDGDNWYRCECASGFAGPDCRININECQSS 830
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,329,127
Number of Sequences: 369166
Number of extensions: 2171849
Number of successful extensions: 7201
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5775
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6728
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6970118400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)