Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_O09
(598 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P41148|ENPL_CANFA Endoplasmin precursor (94 kDa glucose-... 235 7e-62
sp|P08110|ENPL_CHICK Endoplasmin precursor (Heat shock 108 ... 234 9e-62
sp|Q29092|ENPL_PIG Endoplasmin precursor (94 kDa glucose-re... 234 2e-61
sp|Q95M18|ENPL_BOVIN Endoplasmin precursor (94 kDa glucose-... 233 2e-61
sp|P14625|ENPL_HUMAN Endoplasmin precursor (94 kDa glucose-... 233 4e-61
sp|P08712|ENPL_MESAU Endoplasmin (94 kDa glucose-regulated ... 231 8e-61
sp|P08113|ENPL_MOUSE Endoplasmin precursor (Endoplasmic ret... 231 8e-61
sp|O18750|ENPL_RABIT Endoplasmin (94 kDa glucose-regulated ... 211 1e-54
sp|Q04619|HS90B_CHICK Heat shock cognate protein HSP 90-beta 173 3e-43
sp|Q9GKX8|HS90B_HORSE Heat shock protein HSP 90-beta (HSP 84) 172 4e-43
>sp|P41148|ENPL_CANFA Endoplasmin precursor (94 kDa glucose-regulated protein) (GRP94)
Length = 804
Score = 235 bits (599), Expect = 7e-62
Identities = 111/196 (56%), Positives = 146/196 (74%)
Frame = +3
Query: 3 KQDVIYYIAGQSKEELIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSVTEFEGKKLQNLGK 182
KQD IY++AG S++E SP VE++LKKG+EV+Y+ +PVDEY +Q++ EF+GK+ QN+ K
Sbjct: 534 KQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAK 593
Query: 183 EGVKFDDSDKAKEQREIISKEFEPLLKWFKDVALSEHIEKAEISERLHSSPCAVVASTYG 362
EGVKFD+S+K KE RE I KEFEPLL W KD AL + IEKA +S+RL SPCA+VAS YG
Sbjct: 594 EGVKFDESEKTKESREAIEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYG 653
Query: 363 WTGNMERIMKXXXXXXXXXXXXXXXSSQKKILEINPRHPLIKELKRQVEKNPSDEQARDI 542
W+GNMERIMK +SQKK EINPRHPLIK++ R+V+++ D+ D+
Sbjct: 654 WSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIKDMLRRVKEDEDDKTVSDL 713
Query: 543 ALTLYDTANLRSGYSL 590
A+ L++TA LRSGY L
Sbjct: 714 AVVLFETATLRSGYLL 729
>sp|P08110|ENPL_CHICK Endoplasmin precursor (Heat shock 108 kDa protein) (HSP108) (HSP 108)
(Transferrin-binding protein)
Length = 795
Score = 234 bits (598), Expect = 9e-62
Identities = 110/196 (56%), Positives = 147/196 (75%)
Frame = +3
Query: 3 KQDVIYYIAGQSKEELIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSVTEFEGKKLQNLGK 182
KQD IY++AG S++E SP VE++LKKG+EV+Y+ +PVDEY +Q++ EF+GK+ QN+ K
Sbjct: 533 KQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAK 592
Query: 183 EGVKFDDSDKAKEQREIISKEFEPLLKWFKDVALSEHIEKAEISERLHSSPCAVVASTYG 362
EGVKF++S+K+KE RE + KEFEPLL W KD AL + IEKA +S+RL SPCA+VAS YG
Sbjct: 593 EGVKFEESEKSKESREALEKEFEPLLNWMKDKALKDKIEKAVLSQRLTQSPCALVASQYG 652
Query: 363 WTGNMERIMKXXXXXXXXXXXXXXXSSQKKILEINPRHPLIKELKRQVEKNPSDEQARDI 542
W+GNMERIMK +SQKK EINPRHPLIK++ R+V++N D+ D+
Sbjct: 653 WSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIKDMLRRVKENEDDKTVSDL 712
Query: 543 ALTLYDTANLRSGYSL 590
A+ L++TA LRSGY L
Sbjct: 713 AVVLFETATLRSGYML 728
>sp|Q29092|ENPL_PIG Endoplasmin precursor (94 kDa glucose-regulated protein) (GRP94)
(GP96 homolog) (98 kDa protein kinase) (PPK 98) (ppk98)
Length = 804
Score = 234 bits (596), Expect = 2e-61
Identities = 109/196 (55%), Positives = 147/196 (75%)
Frame = +3
Query: 3 KQDVIYYIAGQSKEELIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSVTEFEGKKLQNLGK 182
KQD IY++AG S++E SP VE++LKKG+EV+Y+ +PVDEY +Q++ EF+GK+ QN+ K
Sbjct: 534 KQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAK 593
Query: 183 EGVKFDDSDKAKEQREIISKEFEPLLKWFKDVALSEHIEKAEISERLHSSPCAVVASTYG 362
EGVKFD+S+K+KE RE + KEFEPLL W KD AL + IEKA +S+RL SPCA+VAS YG
Sbjct: 594 EGVKFDESEKSKENREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYG 653
Query: 363 WTGNMERIMKXXXXXXXXXXXXXXXSSQKKILEINPRHPLIKELKRQVEKNPSDEQARDI 542
W+GNMERIMK +SQKK EINPRHPLI+++ R+V+++ D+ D+
Sbjct: 654 WSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRVKEDEDDKTVSDL 713
Query: 543 ALTLYDTANLRSGYSL 590
A+ L++TA LRSGY L
Sbjct: 714 AVVLFETATLRSGYLL 729
>sp|Q95M18|ENPL_BOVIN Endoplasmin precursor (94 kDa glucose-regulated protein) (GRP94)
Length = 804
Score = 233 bits (595), Expect = 2e-61
Identities = 109/196 (55%), Positives = 147/196 (75%)
Frame = +3
Query: 3 KQDVIYYIAGQSKEELIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSVTEFEGKKLQNLGK 182
KQD IY++AG S++E SP VE++LKKG+EV+Y+ +PVDEY +Q++ EF+GK+ QN+ K
Sbjct: 534 KQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAK 593
Query: 183 EGVKFDDSDKAKEQREIISKEFEPLLKWFKDVALSEHIEKAEISERLHSSPCAVVASTYG 362
EGVKFD+S+K+KE RE + KEFEPLL W KD AL + IEKA +S+RL SPCA+VAS YG
Sbjct: 594 EGVKFDESEKSKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYG 653
Query: 363 WTGNMERIMKXXXXXXXXXXXXXXXSSQKKILEINPRHPLIKELKRQVEKNPSDEQARDI 542
W+GNMERIMK +SQKK EINPRHPLI+++ R+V+++ D+ D+
Sbjct: 654 WSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRVKEDEDDKTVSDL 713
Query: 543 ALTLYDTANLRSGYSL 590
A+ L++TA LRSGY L
Sbjct: 714 AVVLFETATLRSGYLL 729
>sp|P14625|ENPL_HUMAN Endoplasmin precursor (94 kDa glucose-regulated protein) (GRP94)
(gp96 homolog) (Tumor rejection antigen 1)
Length = 803
Score = 233 bits (593), Expect = 4e-61
Identities = 108/196 (55%), Positives = 146/196 (74%)
Frame = +3
Query: 3 KQDVIYYIAGQSKEELIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSVTEFEGKKLQNLGK 182
KQD IY++AG S++E SP VE++LKKG+EV+Y+ +PVDEY +Q++ EF+GK+ QN+ K
Sbjct: 534 KQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAK 593
Query: 183 EGVKFDDSDKAKEQREIISKEFEPLLKWFKDVALSEHIEKAEISERLHSSPCAVVASTYG 362
EGVKFD+S+K KE RE + KEFEPLL W KD AL + IEKA +S+RL SPCA+VAS YG
Sbjct: 594 EGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYG 653
Query: 363 WTGNMERIMKXXXXXXXXXXXXXXXSSQKKILEINPRHPLIKELKRQVEKNPSDEQARDI 542
W+GNMERIMK +SQKK EINPRHPLI+++ R+++++ D+ D+
Sbjct: 654 WSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDL 713
Query: 543 ALTLYDTANLRSGYSL 590
A+ L++TA LRSGY L
Sbjct: 714 AVVLFETATLRSGYLL 729
>sp|P08712|ENPL_MESAU Endoplasmin (94 kDa glucose-regulated protein) (GRP94)
Length = 400
Score = 231 bits (590), Expect = 8e-61
Identities = 109/196 (55%), Positives = 145/196 (73%)
Frame = +3
Query: 3 KQDVIYYIAGQSKEELIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSVTEFEGKKLQNLGK 182
KQD IY++AG S++E SP VE++LKKG+EV+Y+ +PVDEY +Q++ EF+GK+ QN+ K
Sbjct: 131 KQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAK 190
Query: 183 EGVKFDDSDKAKEQREIISKEFEPLLKWFKDVALSEHIEKAEISERLHSSPCAVVASTYG 362
EGVKFD+S+K KE RE KEFEPLL W KD AL + IEKA +S+RL SPCA+VAS YG
Sbjct: 191 EGVKFDESEKTKENREATEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYG 250
Query: 363 WTGNMERIMKXXXXXXXXXXXXXXXSSQKKILEINPRHPLIKELKRQVEKNPSDEQARDI 542
W+GNMERIMK +SQKK EINPRHPLI+++ R+V+++ D+ D+
Sbjct: 251 WSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRVKEDEDDKTVLDL 310
Query: 543 ALTLYDTANLRSGYSL 590
A+ L++TA LRSGY L
Sbjct: 311 AVVLFETATLRSGYLL 326
>sp|P08113|ENPL_MOUSE Endoplasmin precursor (Endoplasmic reticulum protein 99) (94 kDa
glucose-regulated protein) (GRP94) (ERP99) (Polymorphic
tumor rejection antigen 1) (Tumor rejection antigen gp96)
Length = 802
Score = 231 bits (590), Expect = 8e-61
Identities = 108/196 (55%), Positives = 145/196 (73%)
Frame = +3
Query: 3 KQDVIYYIAGQSKEELIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSVTEFEGKKLQNLGK 182
KQD IY++AG S++E SP VE++LKKG+EV+Y+ +PVDEY +Q++ EF+GK+ QN+ K
Sbjct: 534 KQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAK 593
Query: 183 EGVKFDDSDKAKEQREIISKEFEPLLKWFKDVALSEHIEKAEISERLHSSPCAVVASTYG 362
EGVKFD+S+K KE RE KEFEPLL W KD AL + IEKA +S+RL SPCA+VAS YG
Sbjct: 594 EGVKFDESEKTKESREATEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYG 653
Query: 363 WTGNMERIMKXXXXXXXXXXXXXXXSSQKKILEINPRHPLIKELKRQVEKNPSDEQARDI 542
W+GNMERIMK +SQKK EINPRHPLI+++ R+++++ D+ D+
Sbjct: 654 WSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVMDL 713
Query: 543 ALTLYDTANLRSGYSL 590
A+ L++TA LRSGY L
Sbjct: 714 AVVLFETATLRSGYLL 729
>sp|O18750|ENPL_RABIT Endoplasmin (94 kDa glucose-regulated protein) (GRP94)
Length = 716
Score = 211 bits (537), Expect = 1e-54
Identities = 106/196 (54%), Positives = 138/196 (70%)
Frame = +3
Query: 3 KQDVIYYIAGQSKEELIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSVTEFEGKKLQNLGK 182
KQD IY++AG S++E SP VE++LKKG+EV+Y+ +PVDEY +Q++ EF+GK+ QN+ K
Sbjct: 453 KQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAK 512
Query: 183 EGVKFDDSDKAKEQREIISKEFEPLLKWFKDVALSEHIEKAEISERLHSSPCAVVASTYG 362
EGVKFD+S+K KE RE KEFEPLL W KD AL + IEKA +S+RL SPCA+VAS YG
Sbjct: 513 EGVKFDESEKTKESREATEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYG 572
Query: 363 WTGNMERIMKXXXXXXXXXXXXXXXSSQKKILEINPRHPLIKELKRQVEKNPSDEQARDI 542
W+ NMERIMK S +K EINPRHPLI+++ R E D+ D+
Sbjct: 573 WSANMERIMKAQAYQTGKDSTKYYAS--QKTFEINPRHPLIRDMLRIKE---DDKTVMDL 627
Query: 543 ALTLYDTANLRSGYSL 590
A+ L++TA LRSGY L
Sbjct: 628 AVVLFETAILRSGYLL 643
>sp|Q04619|HS90B_CHICK Heat shock cognate protein HSP 90-beta
Length = 725
Score = 173 bits (438), Expect = 3e-43
Identities = 88/196 (44%), Positives = 127/196 (64%)
Frame = +3
Query: 6 QDVIYYIAGQSKEELIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSVTEFEGKKLQNLGKE 185
Q IYYI G+SKE++ S VE+V K+GFEVVYM +P+DEY VQ + EF+GK L ++ KE
Sbjct: 481 QKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKTLVSVTKE 540
Query: 186 GVKFDDSDKAKEQREIISKEFEPLLKWFKDVALSEHIEKAEISERLHSSPCAVVASTYGW 365
G++ + ++ K+ E +FE L K K++ L + +EK IS RL SSPC +V STYGW
Sbjct: 541 GLELPEDEEEKKNMEESKAKFETLCKLMKEI-LDKKVEKVTISNRLVSSPCCIVTSTYGW 599
Query: 366 TGNMERIMKXXXXXXXXXXXXXXXSSQKKILEINPRHPLIKELKRQVEKNPSDEQARDIA 545
T NMERIMK KK LEINP HP+++ L+++ + N +D+ +D+
Sbjct: 600 TANMERIMK---AQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKADANKNDKAVKDLV 656
Query: 546 LTLYDTANLRSGYSLQ 593
+ L++TA L SG+SL+
Sbjct: 657 VLLFETALLSSGFSLE 672
>sp|Q9GKX8|HS90B_HORSE Heat shock protein HSP 90-beta (HSP 84)
Length = 724
Score = 172 bits (437), Expect = 4e-43
Identities = 88/196 (44%), Positives = 128/196 (65%)
Frame = +3
Query: 6 QDVIYYIAGQSKEELIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSVTEFEGKKLQNLGKE 185
Q IYYI G+SKE++ S VE+V K+GFEVVYM +P+DEY VQ + EF+GK L ++ KE
Sbjct: 480 QKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKE 539
Query: 186 GVKFDDSDKAKEQREIISKEFEPLLKWFKDVALSEHIEKAEISERLHSSPCAVVASTYGW 365
G++ + ++ K++ E +FE L K K++ L + +EK IS RL SSPC +V STYGW
Sbjct: 540 GLELPEDEEEKKKMEESKAKFENLCKLMKEI-LDKKVEKVTISNRLVSSPCCIVTSTYGW 598
Query: 366 TGNMERIMKXXXXXXXXXXXXXXXSSQKKILEINPRHPLIKELKRQVEKNPSDEQARDIA 545
T NMERIMK KK LEINP HP+++ L+++ E + +D+ +D+
Sbjct: 599 TANMERIMK---AQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLV 655
Query: 546 LTLYDTANLRSGYSLQ 593
+ L++TA L SG+SL+
Sbjct: 656 VLLFETALLSSGFSLE 671
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,832,287
Number of Sequences: 369166
Number of extensions: 1240796
Number of successful extensions: 4400
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4103
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4230
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4553075865
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)