Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_M15
(411 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P42357|HUTH_HUMAN Histidine ammonia-lyase (Histidase) 197 9e-51
sp|P35492|HUTH_MOUSE Histidine ammonia-lyase (Histidase) 195 3e-50
sp|P21213|HUTH_RAT Histidine ammonia-lyase (Histidase) 194 4e-50
sp|Q20502|HUTH_CAEEL Probable histidine ammonia-lyase (Hist... 178 4e-45
sp|Q67JH4|HUTH_SYMTH Histidine ammonia-lyase (Histidase) 158 3e-39
sp|Q5FRR8|HUTH_GLUOX Histidine ammonia-lyase (Histidase) 155 2e-38
sp|Q8RBH4|HUTH_THETN Histidine ammonia-lyase (Histidase) 155 3e-38
sp|Q63SH6|HUTH_BURPS Histidine ammonia-lyase (Histidase) 153 1e-37
sp|Q62LJ6|HUTH_BURMA Histidine ammonia-lyase (Histidase) 153 1e-37
sp|Q9RZ06|HUTH_DEIRA Histidine ammonia-lyase (Histidase) 153 1e-37
>sp|P42357|HUTH_HUMAN Histidine ammonia-lyase (Histidase)
Length = 657
Score = 197 bits (500), Expect = 9e-51
Identities = 101/137 (73%), Positives = 117/137 (85%)
Frame = +1
Query: 1 KALDFLAIGIHELASMSERRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSEN 180
KALD+LAIGIHELA++SERRIERL NP+ S LPAFLV +GG+NSGFM+AH TAAALVSEN
Sbjct: 451 KALDYLAIGIHELAAISERRIERLCNPSLSELPAFLVAEGGLNSGFMIAHCTAAALVSEN 510
Query: 181 KVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPL 360
K L HPSSVDSL+TSA EDHVSMG +AARKAL V+ +VE VLAIELLA+ Q +EFLRPL
Sbjct: 511 KALCHPSSVDSLSTSAATEDHVSMGGWAARKALRVIEHVEQVLAIELLAACQGIEFLRPL 570
Query: 361 KSTEPLEAVVRLIRTTV 411
K+T PLE V L+R+ V
Sbjct: 571 KTTTPLEKVYDLVRSVV 587
>sp|P35492|HUTH_MOUSE Histidine ammonia-lyase (Histidase)
Length = 657
Score = 195 bits (495), Expect = 3e-50
Identities = 100/137 (72%), Positives = 117/137 (85%)
Frame = +1
Query: 1 KALDFLAIGIHELASMSERRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSEN 180
KALD+LAIG+HELA++SERRIERL NP+ S LPAFLV +GG+NSGFM+AH TAAALVSE+
Sbjct: 451 KALDYLAIGVHELAAISERRIERLCNPSLSELPAFLVAEGGLNSGFMIAHCTAAALVSES 510
Query: 181 KVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPL 360
K L HPSSVDSL+TSA EDHVSMG +AARKAL VV +VE VLAIELLA+ Q +EFLRPL
Sbjct: 511 KALCHPSSVDSLSTSAATEDHVSMGGWAARKALRVVEHVEQVLAIELLAACQGIEFLRPL 570
Query: 361 KSTEPLEAVVRLIRTTV 411
K+T PLE V L+R+ V
Sbjct: 571 KTTTPLEKVYDLVRSVV 587
>sp|P21213|HUTH_RAT Histidine ammonia-lyase (Histidase)
Length = 657
Score = 194 bits (494), Expect = 4e-50
Identities = 99/137 (72%), Positives = 117/137 (85%)
Frame = +1
Query: 1 KALDFLAIGIHELASMSERRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSEN 180
KALD+LAIG+HELA++SERRIERL NP+ S LPAFLV +GG+NSGFM+AH TAAALVSE+
Sbjct: 451 KALDYLAIGVHELAAISERRIERLCNPSLSELPAFLVAEGGLNSGFMIAHCTAAALVSES 510
Query: 181 KVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPL 360
K L HPSSVDSL+TSA EDHVSMG +AARKAL V+ +VE VLAIELLA+ Q +EFLRPL
Sbjct: 511 KALCHPSSVDSLSTSAATEDHVSMGGWAARKALRVIEHVEQVLAIELLAACQGIEFLRPL 570
Query: 361 KSTEPLEAVVRLIRTTV 411
K+T PLE V L+R+ V
Sbjct: 571 KTTTPLEKVYDLVRSVV 587
>sp|Q20502|HUTH_CAEEL Probable histidine ammonia-lyase (Histidase)
Length = 677
Score = 178 bits (451), Expect = 4e-45
Identities = 92/135 (68%), Positives = 107/135 (79%)
Frame = +1
Query: 1 KALDFLAIGIHELASMSERRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSEN 180
KALDFLAI + ELA MSERR+ERLVN SGLP FL DGG+NSGFM + AA+LVSEN
Sbjct: 467 KALDFLAIAVAELAQMSERRLERLVNKELSGLPTFLTPDGGLNSGFMTVQLCAASLVSEN 526
Query: 181 KVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPL 360
KVL HPSSVDS+ TS QEDHVSMG FAARKAL VV +VE VLA+ELLA+ Q +EFL+PL
Sbjct: 527 KVLCHPSSVDSIPTSCNQEDHVSMGGFAARKALTVVEHVEAVLAMELLAACQGIEFLKPL 586
Query: 361 KSTEPLEAVVRLIRT 405
ST PL + +L+R+
Sbjct: 587 ISTAPLHKIYQLVRS 601
>sp|Q67JH4|HUTH_SYMTH Histidine ammonia-lyase (Histidase)
Length = 507
Score = 158 bits (400), Expect = 3e-39
Identities = 82/136 (60%), Positives = 101/136 (74%)
Frame = +1
Query: 4 ALDFLAIGIHELASMSERRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENK 183
ALD+LAI + EL ++ERRIERLVNP SGLPAFL ++GG++SG M+ TAA+LVSENK
Sbjct: 335 ALDYLAIAVAELGDIAERRIERLVNPQLSGLPAFLTRNGGVHSGLMITQYTAASLVSENK 394
Query: 184 VLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLK 363
VL HP+SVDS+ +SA QEDHVSMG AARKA +V++NV VLAIELL + QALEF+ P +
Sbjct: 395 VLAHPASVDSIPSSANQEDHVSMGTTAARKARQVIANVRRVLAIELLCAAQALEFVGPER 454
Query: 364 STEPLEAVVRLIRTTV 411
A IR V
Sbjct: 455 LAPATRAAYAAIRERV 470
>sp|Q5FRR8|HUTH_GLUOX Histidine ammonia-lyase (Histidase)
Length = 515
Score = 155 bits (393), Expect = 2e-38
Identities = 77/136 (56%), Positives = 102/136 (75%)
Frame = +1
Query: 4 ALDFLAIGIHELASMSERRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENK 183
A D +AI + E+ +++ERR+ LV+ SGLP FLV+D G+NSGFM+A VTAAAL SENK
Sbjct: 340 AADLMAIAVSEVGAIAERRLALLVDAQMSGLPPFLVQDSGLNSGFMIAQVTAAALASENK 399
Query: 184 VLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLK 363
L HP+SVDSL TSA QEDHVSM FAAR+ ++V NV ++A+E LA+VQ L+FL PL+
Sbjct: 400 TLAHPASVDSLPTSANQEDHVSMATFAARRVGDIVDNVRTIIAVEYLAAVQGLDFLAPLE 459
Query: 364 STEPLEAVVRLIRTTV 411
++ PL V + +R TV
Sbjct: 460 TSAPLLEVAKTLRKTV 475
>sp|Q8RBH4|HUTH_THETN Histidine ammonia-lyase (Histidase)
Length = 508
Score = 155 bits (392), Expect = 3e-38
Identities = 81/136 (59%), Positives = 103/136 (75%)
Frame = +1
Query: 4 ALDFLAIGIHELASMSERRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENK 183
A+DFL+I + E+A++SERRIERLVN + LP FL + GG+NSG M+A TAA+LVSENK
Sbjct: 336 AMDFLSIALSEIANISERRIERLVNYQLNDLPPFLTEKGGLNSGMMIAQYTAASLVSENK 395
Query: 184 VLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLK 363
VL+HP+SVDS+ +SA QEDHVSMG AARKA EV+ NV VLAIELL + QALEF + K
Sbjct: 396 VLSHPASVDSIPSSANQEDHVSMGTIAARKAREVLKNVTTVLAIELLTASQALEFRKGFK 455
Query: 364 STEPLEAVVRLIRTTV 411
+ + + RL+R V
Sbjct: 456 RGKGTDRIYRLVREKV 471
>sp|Q63SH6|HUTH_BURPS Histidine ammonia-lyase (Histidase)
Length = 507
Score = 153 bits (386), Expect = 1e-37
Identities = 78/136 (57%), Positives = 98/136 (72%)
Frame = +1
Query: 4 ALDFLAIGIHELASMSERRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENK 183
A D LAI E+ +++ERRI L++ SGLP FLVKDGG+NSGFM+AHVTAAAL SENK
Sbjct: 335 AADNLAIAAAEIGALAERRIALLIDATLSGLPPFLVKDGGVNSGFMIAHVTAAALASENK 394
Query: 184 VLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLK 363
L HP+SVDSL TSA QEDHVSM FAARK ++ NV N+LAIELLA+ Q ++ P
Sbjct: 395 TLAHPASVDSLPTSANQEDHVSMATFAARKLADIAENVANILAIELLAAAQGVDLRAPHA 454
Query: 364 STEPLEAVVRLIRTTV 411
++ L+ ++ IR V
Sbjct: 455 TSPALQHAMKTIRADV 470
>sp|Q62LJ6|HUTH_BURMA Histidine ammonia-lyase (Histidase)
Length = 507
Score = 153 bits (386), Expect = 1e-37
Identities = 78/136 (57%), Positives = 98/136 (72%)
Frame = +1
Query: 4 ALDFLAIGIHELASMSERRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENK 183
A D LAI E+ +++ERRI L++ SGLP FLVKDGG+NSGFM+AHVTAAAL SENK
Sbjct: 335 AADNLAIAAAEIGALAERRIALLIDATLSGLPPFLVKDGGVNSGFMIAHVTAAALASENK 394
Query: 184 VLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLK 363
L HP+SVDSL TSA QEDHVSM FAARK ++ NV N+LAIELLA+ Q ++ P
Sbjct: 395 TLAHPASVDSLPTSANQEDHVSMATFAARKLTDIAENVANILAIELLAAAQGVDLRAPHA 454
Query: 364 STEPLEAVVRLIRTTV 411
++ L+ ++ IR V
Sbjct: 455 TSPALQHAMKTIRADV 470
>sp|Q9RZ06|HUTH_DEIRA Histidine ammonia-lyase (Histidase)
Length = 524
Score = 153 bits (386), Expect = 1e-37
Identities = 78/135 (57%), Positives = 105/135 (77%)
Frame = +1
Query: 7 LDFLAIGIHELASMSERRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENKV 186
+D L + + EL S+SERR E+L+NPA SGLPAFL +GG+NSGFM+A T+AALVSENKV
Sbjct: 335 IDALKVAVAELGSISERRTEQLLNPALSGLPAFLTPNGGLNSGFMIAQYTSAALVSENKV 394
Query: 187 LTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLKS 366
L+HP+SVDS+ TSA QEDHVSMGA AAR+ ++V+NV+ VL+IELL + Q L+F + L++
Sbjct: 395 LSHPASVDSIPTSANQEDHVSMGAHAARQLRQIVANVQTVLSIELLCAAQGLDF-QQLRA 453
Query: 367 TEPLEAVVRLIRTTV 411
++A +RT V
Sbjct: 454 GRGVQAAYEYVRTFV 468
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.317 0.131 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,776,272
Number of Sequences: 369166
Number of extensions: 813936
Number of successful extensions: 2188
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2123
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2164
length of database: 68,354,980
effective HSP length: 99
effective length of database: 50,066,215
effective search space used: 1852449955
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)