Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_M07
(840 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q59037|SMC_METJA Chromosome partition protein smc homolog 50 1e-05
sp|Q9M7J4|MFP1_TOBAC MAR binding filament-like protein 1-1 49 1e-05
sp|P13542|MYH8_MOUSE Myosin-8 (Myosin heavy chain, skeletal... 47 5e-05
sp|P54697|MYOJ_DICDI Myosin IJ heavy chain 47 7e-05
sp|Q80UK7|SAS6_MOUSE Spindle assembly abnormal protein 6 ho... 46 1e-04
sp|P35748|MYH11_RABIT Myosin-11 (Myosin heavy chain, smooth... 46 1e-04
sp||Q63862_2 [Segment 2 of 2] Myosin-11 (Myosin heavy chain... 45 2e-04
sp|P35749|MYH11_HUMAN Myosin-11 (Myosin heavy chain, smooth... 45 2e-04
sp|Q28641|MYH4_RABIT Myosin-4 (Myosin heavy chain, skeletal... 45 3e-04
sp|Q96AA8|Y0555_HUMAN Hypothetical protein KIAA0555 44 4e-04
>sp|Q59037|SMC_METJA Chromosome partition protein smc homolog
Length = 1169
Score = 49.7 bits (117), Expect = 1e-05
Identities = 52/257 (20%), Positives = 119/257 (46%), Gaps = 11/257 (4%)
Frame = +2
Query: 101 LLEVNALRAKVAEMRE----DSLQQEQTIREEVRQEYNAMVQNLFSVAFEQKMQIDVYRE 268
+ E N ++ K E++ + L++ REE+ N + + + ++ I+ +E
Sbjct: 733 IAEKNTIKIKELELKNKDILEELEELNLKREEILNRINEIESKINELIERREKIINELKE 792
Query: 269 YLHDATLKRIQEVRTEAAIEMNKVKEKSGAKVTADDELAERNLKLSKE--LTSLHQQNIH 442
Y D LKR+ E+ E K+ EK AK+ + ++ L L KE + + + N
Sbjct: 793 YESDENLKRMNEIEGEL-----KILEKEKAKLKNE---IDKGLTLVKEILIPKIEELNKK 844
Query: 443 LKQMMSRMKSLFNWHHTFIKCNFQKAIANIEKDRDKYKNSVTVVQMNSEQKVQIMG--EE 616
+ +++++ K + + +F K + +K ++ +E+ R +Y+ ++ +E+K Q+ E
Sbjct: 845 VSELINK-KVILEKNISFYKESIEKNLSILEEKRKRYEELAKNLKELTEKKEQLEKEIET 903
Query: 617 LDRLKQYLTSTEKELNDLRKTLXXXXXXXXXXXHAAERKAATDKQMALVKQMH---IDQL 787
L+R ++ + +++ + L ERK +++ + K++ I++L
Sbjct: 904 LERERREILRKVRDIENRINELMVEKAKYESKLEEEERKLYLCEKVDVSKELEKKDIEEL 963
Query: 788 MSEITEKNSNIATMSRV 838
I E + I ++ V
Sbjct: 964 EIYIGELENEIKSLEPV 980
Score = 33.1 bits (74), Expect = 0.98
Identities = 36/203 (17%), Positives = 95/203 (46%), Gaps = 10/203 (4%)
Frame = +2
Query: 101 LLEVNALRAKVAEMREDSLQQEQTIREEVRQEYNAMVQNLFSVAFEQKMQIDVYREYLHD 280
L+E+ +R E L++E+ E+ + + +++ ++ ++V E + +
Sbjct: 191 LIEMIDIRISEVENNLKKLKKEKEDAEKYIKLNEELKAAKYALILKKVSYLNVLLENIQN 250
Query: 281 ATLKRIQEVRTEAAIEMNKVK-EKSGAKVTADDELAERNLKLSKELTSLHQQNIHLKQMM 457
+K ++E++ E ++ ++ E K+ ++ + E N K ++E+ LH+ L+ +
Sbjct: 251 -DIKNLEELKNEFLSKVREIDVEIENLKLRLNNIINELNEKGNEEVLELHKSIKELEVEI 309
Query: 458 SRMKSLFNWHHTFIKC------NFQKAIANIEKDRDKYKNSVTVVQMNS---EQKVQIMG 610
K + + +K N +K I +K + ++S+ + E+K++ +
Sbjct: 310 ENDKKVLDSSINELKKVEVEIENKKKEIKETQKKIIENRDSIIEKEQQIKEIEEKIKNLN 369
Query: 611 EELDRLKQYLTSTEKELNDLRKT 679
E +RLK+ + +E + L+++
Sbjct: 370 YEKERLKEAIAESESIIKHLKES 392
>sp|Q9M7J4|MFP1_TOBAC MAR binding filament-like protein 1-1
Length = 722
Score = 49.3 bits (116), Expect = 1e-05
Identities = 62/282 (21%), Positives = 129/282 (45%), Gaps = 19/282 (6%)
Frame = +2
Query: 11 IEDMKQQLLQKELATIVDVQ--FQ----------------LADQAHSLLLEVNALRAKVA 136
IE MK +L +KE AT V ++ FQ ++ +L+ ++N+ ++ V
Sbjct: 146 IESMKNKLKEKE-ATFVSMEKKFQSELLNERDIRNNQLKRAGEERQALVNQLNSAKSTVT 204
Query: 137 EMREDSLQQEQTIREEVRQEYNAMVQNLFSVAFEQKMQIDVYREYLHDATLKRIQEVRTE 316
+ ++ LQ+E+ I EE+ + + NL + ++K + +E L IQ ++ +
Sbjct: 205 NLGQE-LQKEKRIAEELIVQIEGLQNNLMQMKEDKKKLQEELKE-----KLDLIQVLQEK 258
Query: 317 AAIEMNKVKEKSGAKVTADDELAERNLKLSKELTSLHQQN-IHLKQMMSRMKSLFNWHHT 493
+ ++K+K + + +LAE+ ++ K L+S++Q++ L + S +K L
Sbjct: 259 ITLLTTEIKDKEASLQSTTSKLAEKESEVDK-LSSMYQESQDQLMNLTSEIKEL------ 311
Query: 494 FIKCNFQKAIANIEKDRDKYKNSVTVVQMNSEQKVQIMGEELDRLKQYLTSTEKELNDLR 673
K QK +E R+ N V++NS + E D K+ L + +KE ++ +
Sbjct: 312 --KVEVQKRERELELKRESEDN--LNVRLNS------LLVERDESKKELDAIQKEYSEFK 361
Query: 674 KTLXXXXXXXXXXXHAAERKAATDKQMALVKQMHIDQLMSEI 799
+E+K A+D ++ ++ + QL ++
Sbjct: 362 S--------------ISEKKVASDAKLLGEQEKRLHQLEEQL 389
>sp|P13542|MYH8_MOUSE Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)
(MyHC-perinatal)
Length = 1937
Score = 47.4 bits (111), Expect = 5e-05
Identities = 62/293 (21%), Positives = 136/293 (46%), Gaps = 25/293 (8%)
Frame = +2
Query: 23 KQQLLQKELATIVDVQFQLADQAHSLLLEVNALRAKVAEMREDSLQQEQTIREEVRQEYN 202
K+ L + T+ D+Q + D+ ++L L +V ++ E SL+QE+ +R ++ +
Sbjct: 999 KKALQEAHQQTLDDLQAE-EDKVNTLTKAKTKLEQQVDDL-EGSLEQEKKLRMDLERAKR 1056
Query: 203 AMVQNLFSVAFEQKMQIDVYREYLHDATLKR-------IQEVRTEAAIEMN---KVKEKS 352
+ +L +A E M I+ ++ L + K+ I ++ E A+E+ K+KE
Sbjct: 1057 KLEGDL-KLAQESTMDIENDKQQLDEKLKKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1115
Query: 353 GAKVTADDEL-AER--NLKLSKELTSLHQQNIHLKQMMSRMKSLFNWHHTFIKCN----- 508
++E+ AER K K+ + L ++ L+++ R++ ++ N
Sbjct: 1116 ARIEELEEEIEAERASRAKAEKQRSDLSRE---LEEISERLEEAGGATSAQVEMNKKRET 1172
Query: 509 -FQKAIANIEKDRDKYKNSVTVVQMNSEQKVQIMGEELDRLKQYLTSTEKELNDLRKTLX 685
FQK ++E+ +++ + ++ V +GE++D L++ EKE ++L+ +
Sbjct: 1173 EFQKLRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEID 1232
Query: 686 XXXXXXXXXXHA---AERKAAT-DKQMALVKQMHIDQ--LMSEITEKNSNIAT 826
A E+ T + Q++ +K +Q L++E+T + + + T
Sbjct: 1233 DLSSNAEAIAKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINELTAQRARLQT 1285
>sp|P54697|MYOJ_DICDI Myosin IJ heavy chain
Length = 2245
Score = 47.0 bits (110), Expect = 7e-05
Identities = 63/294 (21%), Positives = 126/294 (42%), Gaps = 16/294 (5%)
Frame = +2
Query: 2 EREIEDMKQQL---------LQKELATIVDVQFQLADQAHSLLLEVNALRAKVAEMRE-- 148
ERE+E+ KQ + L+K+L + Q + Q E+ LR K + +E
Sbjct: 1483 ERELEEKKQHITRIDDERDELKKQLTQLQQQHEQSSTQLLLAQNELERLRKKELKYKERG 1542
Query: 149 --DSLQQEQTIRE--EVRQEYNAMVQNLFSVAFEQKMQIDVYREYLHDATLKRIQEVRTE 316
S QQ+Q E +R N +++L E+K D +A +R ++ +
Sbjct: 1543 HETSKQQDQFNMEIQSLRITNNDQLKSLQDYEQEKKKLKDKLSSSKQEAQQQRESIIKMD 1602
Query: 317 AAIEMNKVKEKSGAKVTADDELAERNLKLSKELTSLHQQNIHLKQMMSRMKSLFNWHHTF 496
A E++ +K+ S + ++ +RN +L E ++L++Q L Q S + S
Sbjct: 1603 A--ELSAIKQHSQWVENSFTDMKQRNQELI-ESSALYKQQ--LLQQTSTIDSTIKEKENE 1657
Query: 497 IKCNFQKAIANIEKDRDKYKNSVTVVQMNSEQKVQIMGEELDRLKQYLTSTEKELNDLRK 676
I Q+ + + + K + ++ +++ + ++L++L Q + N++ K
Sbjct: 1658 IS-KLQQQLETSNQQLHQLKEELNSMKQSNQLESTEQSKQLNQLIQENQQLKSVTNEISK 1716
Query: 677 TLXXXXXXXXXXXHAAERKAATDKQMALVKQMHIDQ-LMSEITEKNSNIATMSR 835
L + + + K+M++ Q HID+ EI + S IA + +
Sbjct: 1717 QLDDAVFENQKINNTIKEQEIKSKRMSVELQQHIDEGKQQEIQQLQSTIAQLKQ 1770
>sp|Q80UK7|SAS6_MOUSE Spindle assembly abnormal protein 6 homolog
Length = 654
Score = 46.2 bits (108), Expect = 1e-04
Identities = 41/145 (28%), Positives = 70/145 (48%), Gaps = 8/145 (5%)
Frame = +2
Query: 248 QIDVYREYLHDATLKRIQEVRTEAAIEMNKVKEKSGAKVTADDELA--------ERNLKL 403
Q+ + +E L + ++ + ++R+E A + K ++TA+ E A +++ +
Sbjct: 177 QLHITQETLSEK-MQELDKLRSEWASHTASLTNKHSQELTAEKEKALQTQVQCQQQHEQQ 235
Query: 404 SKELTSLHQQNIHLKQMMSRMKSLFNWHHTFIKCNFQKAIANIEKDRDKYKNSVTVVQMN 583
KEL +LHQ+NIH Q+ SR+ L AN E KYK TV ++
Sbjct: 236 KKELETLHQRNIH--QLQSRLSEL--------------EAANKELTERKYKGDSTVRELK 279
Query: 584 SEQKVQIMGEELDRLKQYLTSTEKE 658
+ K+ + EEL R KQ + S +E
Sbjct: 280 A--KLAGVEEELQRAKQEVLSLRRE 302
>sp|P35748|MYH11_RABIT Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Length = 1972
Score = 46.2 bits (108), Expect = 1e-04
Identities = 55/279 (19%), Positives = 113/279 (40%), Gaps = 3/279 (1%)
Frame = +2
Query: 5 REIEDMKQQLLQKELATIVDVQFQLADQAHSLLLEVNALRAKVAEMRE--DSLQQEQTIR 178
+E + ++L+ E+ +V + + H L AL ++ EM+ + L+ E
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Query: 179 EEVRQEYNAMVQNLFSVAFEQKMQI-DVYREYLHDATLKRIQEVRTEAAIEMNKVKEKSG 355
E+ + +Q L V FE+ +Q D E +++ E TE E + +
Sbjct: 1559 EDAKLRLEVNMQAL-KVQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1617
Query: 356 AKVTADDELAERNLKLSKELTSLHQQNIHLKQMMSRMKSLFNWHHTFIKCNFQKAIANIE 535
AK + +L + L+ + + L ++ ++MK +FQ+ + +
Sbjct: 1618 AKKKLEGDLKDLELQADSAIKGREEAIKQLLKLQAQMK------------DFQRELEDAR 1665
Query: 536 KDRDKYKNSVTVVQMNSEQKVQIMGEELDRLKQYLTSTEKELNDLRKTLXXXXXXXXXXX 715
RD+ + +E+K + + +L +L++ L + E+ + L
Sbjct: 1666 ASRDE----IFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEKEELAEELAS 1719
Query: 716 HAAERKAATDKQMALVKQMHIDQLMSEITEKNSNIATMS 832
+ R A D++ L + I QL E+ E+ N+ MS
Sbjct: 1720 SLSGRNALQDEKRRL--EARIAQLEEELEEEQGNMEAMS 1756
>sp||Q63862_2 [Segment 2 of 2] Myosin-11 (Myosin heavy chain, smooth muscle
isoform) (SMMHC)
Length = 621
Score = 45.4 bits (106), Expect = 2e-04
Identities = 55/279 (19%), Positives = 112/279 (40%), Gaps = 3/279 (1%)
Frame = +2
Query: 5 REIEDMKQQLLQKELATIVDVQFQLADQAHSLLLEVNALRAKVAEMRE--DSLQQEQTIR 178
+E + ++L+ E+ +V + + H L AL ++ EMR + L+ E
Sbjct: 148 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMRTQLEELEDELQAT 207
Query: 179 EEVRQEYNAMVQNLFSVAFEQKMQI-DVYREYLHDATLKRIQEVRTEAAIEMNKVKEKSG 355
E+ + +Q L FE+ +Q D E +++ E TE E + +
Sbjct: 208 EDAKLRLEVNMQAL-KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 266
Query: 356 AKVTADDELAERNLKLSKELTSLHQQNIHLKQMMSRMKSLFNWHHTFIKCNFQKAIANIE 535
AK + +L + L+ + + L+++ ++MK +FQ+ + +
Sbjct: 267 AKKKLEGDLKDLELQADSAVKGREEAIKQLRKLQAQMK------------DFQRELDDAR 314
Query: 536 KDRDKYKNSVTVVQMNSEQKVQIMGEELDRLKQYLTSTEKELNDLRKTLXXXXXXXXXXX 715
RD+ + +E+K + + EL +L++ L + E+ + L
Sbjct: 315 ASRDE----IFATSKENEKKAKSLEAELMQLQEDLAAAERARK--QADLEKEELAEELAS 368
Query: 716 HAAERKAATDKQMALVKQMHIDQLMSEITEKNSNIATMS 832
+ R D++ L + I QL E+ E+ N+ MS
Sbjct: 369 SLSGRNTLQDEKRRL--EARIAQLEEELEEEQGNMEAMS 405
>sp|P35749|MYH11_HUMAN Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Length = 1972
Score = 45.1 bits (105), Expect = 2e-04
Identities = 54/279 (19%), Positives = 113/279 (40%), Gaps = 3/279 (1%)
Frame = +2
Query: 5 REIEDMKQQLLQKELATIVDVQFQLADQAHSLLLEVNALRAKVAEMRE--DSLQQEQTIR 178
+E + ++L+ E+ +V + + H L AL ++ EM+ + L+ E
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Query: 179 EEVRQEYNAMVQNLFSVAFEQKMQI-DVYREYLHDATLKRIQEVRTEAAIEMNKVKEKSG 355
E+ + +Q L FE+ +Q D E +++ E TE E + +
Sbjct: 1559 EDAKLRLEVNMQAL-KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1617
Query: 356 AKVTADDELAERNLKLSKELTSLHQQNIHLKQMMSRMKSLFNWHHTFIKCNFQKAIANIE 535
AK + +L + L+ + + L+++ ++MK +FQ+ + +
Sbjct: 1618 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK------------DFQRELEDAR 1665
Query: 536 KDRDKYKNSVTVVQMNSEQKVQIMGEELDRLKQYLTSTEKELNDLRKTLXXXXXXXXXXX 715
RD+ + +E+K + + +L +L++ L + E+ + L
Sbjct: 1666 ASRDE----IFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEKEELAEELAS 1719
Query: 716 HAAERKAATDKQMALVKQMHIDQLMSEITEKNSNIATMS 832
+ R A D++ L + I QL E+ E+ N+ MS
Sbjct: 1720 SLSGRNALQDEKRRL--EARIAQLEEELEEEQGNMEAMS 1756
>sp|Q28641|MYH4_RABIT Myosin-4 (Myosin heavy chain, skeletal muscle, juvenile)
Length = 1938
Score = 44.7 bits (104), Expect = 3e-04
Identities = 54/236 (22%), Positives = 111/236 (47%), Gaps = 19/236 (8%)
Frame = +2
Query: 23 KQQLLQKELATIVDVQFQLADQAHSLLLEVNALRAKVAEMREDSLQQEQTIREEVRQEYN 202
K+ L + T+ D+Q + D+ ++L L +V ++ E SL+QE+ IR ++ +
Sbjct: 999 KKALQEAHQQTLDDLQAE-EDKVNTLTKAKTKLEQQVDDL-EGSLEQEKKIRMDLERAKR 1056
Query: 203 AMVQNLFSVAFEQKMQIDVYREYLHDATLKRIQE-------VRTEAAIEMN---KVKEKS 352
+ +L +A E M I+ ++ L + K+ E + E A+ M K+KE
Sbjct: 1057 KLEGDL-KLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQ 1115
Query: 353 GAKVTADDEL-AER--NLKLSKELTSLHQQNIHLKQMMSRMKSLFNWHHTFIKCN----- 508
++E+ AER K K+ + L ++ L+++ R++ I+ N
Sbjct: 1116 ARIEELEEEIEAERASRAKAEKQRSDLSRE---LEEISERLEEAGGATSAQIEMNKKREA 1172
Query: 509 -FQKAIANIEKDRDKYKNSVTVVQMNSEQKVQIMGEELDRLKQYLTSTEKELNDLR 673
FQK ++E+ +++ + ++ V +GE++D L++ EKE ++L+
Sbjct: 1173 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSELK 1228
>sp|Q96AA8|Y0555_HUMAN Hypothetical protein KIAA0555
Length = 810
Score = 44.3 bits (103), Expect = 4e-04
Identities = 51/254 (20%), Positives = 115/254 (45%), Gaps = 18/254 (7%)
Frame = +2
Query: 62 DVQFQLADQAHSLLLEVNALRAKVAEMREDSLQQEQTIREEVRQEYNAMVQNLFSVAFEQ 241
D++ +L D + +E++ ++KV+++ + Q+ + IRE ++++ +V L + E+
Sbjct: 25 DLRTKLTD----IQIELHQEKSKVSKLEREKTQEAKRIRELEQRKHTVLVTELKAKLHEE 80
Query: 242 KM-QIDVYREYL---HDATLKRIQEVRTE----------AAIEMNKVKEKSGAKVTADDE 379
KM ++ RE L H+ + R +VR A + + K ++ + A +E
Sbjct: 81 KMKELQAVRENLIKQHEQEMSRTVKVRDGEIQRLKSALCALRDGSSDKVRTALTIEAREE 140
Query: 380 LAE----RNLKLSKELTSLHQQNIHLKQMMSRMKSLFNWHHTFIKCNFQKAIANIEKDRD 547
+ LKL +E+ L + + +S M I+ + KA ++ +
Sbjct: 141 ARKLFDTERLKLLQEIADLKTAKKQVDEALSNM----------IQADKIKA-GDLRSEHQ 189
Query: 548 KYKNSVTVVQMNSEQKVQIMGEELDRLKQYLTSTEKELNDLRKTLXXXXXXXXXXXHAAE 727
++ +++ ++ SE+ ++ + +E+ + + S EKEL +
Sbjct: 190 SHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELETQTGYVQKLQL---------- 239
Query: 728 RKAATDKQMALVKQ 769
+K A D+Q+ LVK+
Sbjct: 240 QKEALDEQLFLVKE 253
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,890,252
Number of Sequences: 369166
Number of extensions: 1353591
Number of successful extensions: 5627
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5224
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5594
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8197207050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)