Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_M02
(495 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P46872|KRP85_STRPU Kinesin-II 85 kDa subunit (KRP-85/95 ... 103 2e-22
sp|P28741|KIF3A_MOUSE Kinesin-like protein KIF3A (Microtubu... 101 8e-22
sp|Q9Y496|KIF3A_HUMAN Kinesin-like protein KIF3A (Microtubu... 100 1e-21
sp|P46871|KRP95_STRPU Kinesin-II 95 kDa subunit (KRP-85/95 ... 74 2e-13
sp|O14782|KIF3C_HUMAN Kinesin-like protein KIF3C 61 2e-09
sp|O55165|KIF3C_RAT Kinesin-like protein KIF3C 59 6e-09
sp|O35066|KIF3C_MOUSE Kinesin-like protein KIF3C 58 1e-08
sp|O15066|KIF3B_HUMAN Kinesin-like protein KIF3B (Microtubu... 57 3e-08
sp|Q61771|KIF3B_MOUSE Kinesin-like protein KIF3B (Microtubu... 56 4e-08
sp|P46869|FLA10_CHLRE Kinesin-like protein FLA10 (KHP1 prot... 47 3e-05
>sp|P46872|KRP85_STRPU Kinesin-II 85 kDa subunit (KRP-85/95 85 kDa subunit)
Length = 699
Score = 103 bits (257), Expect = 2e-22
Identities = 53/157 (33%), Positives = 96/157 (61%), Gaps = 2/157 (1%)
Frame = +3
Query: 18 DENGVERRIRKPKKIRSDK--ISKQRLAEIERSIDENRRKLEQQKDMVAEEKDRVQQDLV 191
DE E ++K +K ++ K +S + +A +++ IDE ++ LE++KDMV E+++ V ++L
Sbjct: 391 DEEAGEGGVKKKRKGKNPKRKLSPEIMAAMQKKIDEEKKALEEKKDMVEEDRNTVHRELQ 450
Query: 192 EKENKLAKARQEQQMLRNRMTDLQRKIIVGGXXXXXXXXXXXXXXXXXXXXXXHHKQTEV 371
+E++L KA+ +Q++L ++ +Q+K+IVGG +
Sbjct: 451 RRESELHKAQDDQKILNEKLNAIQKKLIVGGVDLLAKSEEQEQLLEQSALEMKERMAKQE 510
Query: 372 DMRKKLQEKEEERMNIEVQYNSLQDEAADKKKRVKKI 482
MRK ++E+E+ERM+IE +Y+SLQDEA K K++KK+
Sbjct: 511 SMRKMMEEREQERMDIEEKYSSLQDEAHGKTKKLKKV 547
>sp|P28741|KIF3A_MOUSE Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin
motor 3A)
Length = 701
Score = 101 bits (252), Expect = 8e-22
Identities = 54/160 (33%), Positives = 94/160 (58%)
Frame = +3
Query: 3 EEVVIDENGVERRIRKPKKIRSDKISKQRLAEIERSIDENRRKLEQQKDMVAEEKDRVQQ 182
EE + E+G +R+ R+ + + K+S ++ E++ IDE R+ LE + DM EE+++ +
Sbjct: 393 EEGELGEDGEKRKKRRDQAGKK-KVSPDKMVEMQAKIDEERKALETKLDMEEEERNKARA 451
Query: 183 DLVEKENKLAKARQEQQMLRNRMTDLQRKIIVGGXXXXXXXXXXXXXXXXXXXXXXHHKQ 362
+L +E L KA+QE Q L +++ L++K+IVGG ++
Sbjct: 452 ELERREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRR 511
Query: 363 TEVDMRKKLQEKEEERMNIEVQYNSLQDEAADKKKRVKKI 482
+RK+L+EKE+ER++IE +Y SLQ+EA K K++KK+
Sbjct: 512 RAEQLRKELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKV 551
>sp|Q9Y496|KIF3A_HUMAN Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin
motor 3A)
Length = 702
Score = 100 bits (250), Expect = 1e-21
Identities = 53/160 (33%), Positives = 95/160 (59%)
Frame = +3
Query: 3 EEVVIDENGVERRIRKPKKIRSDKISKQRLAEIERSIDENRRKLEQQKDMVAEEKDRVQQ 182
EE + E+G +R+ R+ + + K+S ++ E++ IDE R+ LE + DM EE+++ +
Sbjct: 394 EEGEVGEDGEKRKKRRDQTGKK-KVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARA 452
Query: 183 DLVEKENKLAKARQEQQMLRNRMTDLQRKIIVGGXXXXXXXXXXXXXXXXXXXXXXHHKQ 362
+L ++E L KA+QE Q L +++ L++K+IVGG ++
Sbjct: 453 ELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRK 512
Query: 363 TEVDMRKKLQEKEEERMNIEVQYNSLQDEAADKKKRVKKI 482
+R++L+EKE+ER++IE +Y SLQ+EA K K++KK+
Sbjct: 513 RAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKV 552
>sp|P46871|KRP95_STRPU Kinesin-II 95 kDa subunit (KRP-85/95 95 kDa subunit)
Length = 742
Score = 73.6 bits (179), Expect = 2e-13
Identities = 37/155 (23%), Positives = 82/155 (52%), Gaps = 1/155 (0%)
Frame = +3
Query: 21 ENGVERRIRKPKKIRSDKISKQRL-AEIERSIDENRRKLEQQKDMVAEEKDRVQQDLVEK 197
E G + I + D++ ++ + E ++ ++E + K+ + M+AEEK ++ ++ ++
Sbjct: 387 EQGGDDDIEDETEEEGDEMDEEEMYKESQQKLEEEKEKIMANQSMIAEEKQKLLSEVQKR 446
Query: 198 ENKLAKARQEQQMLRNRMTDLQRKIIVGGXXXXXXXXXXXXXXXXXXXXXXHHKQTEVDM 377
+ ++ K Q+++ML ++ ++ K++VGG K E DM
Sbjct: 447 QGEIKKEHQQKEMLEGKIKAMESKLLVGGKSIVDHTNEQQRKIEEQRLLLAEEKNRERDM 506
Query: 378 RKKLQEKEEERMNIEVQYNSLQDEAADKKKRVKKI 482
+KL+E++++ + IE ++SLQ E K K++KK+
Sbjct: 507 ERKLKEQDDKTVEIEGTFSSLQQEVEVKTKKLKKL 541
Score = 30.0 bits (66), Expect = 3.1
Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 5/69 (7%)
Frame = +3
Query: 72 KISKQRL--AEIERSIDENRRKLEQQKDMVAEEK---DRVQQDLVEKENKLAKARQEQQM 236
KI +QRL AE + + RKL++Q D E + +QQ++ K KL K + Q
Sbjct: 488 KIEEQRLLLAEEKNRERDMERKLKEQDDKTVEIEGTFSSLQQEVEVKTKKLKKLFAKLQS 547
Query: 237 LRNRMTDLQ 263
++ + DLQ
Sbjct: 548 YKSDIQDLQ 556
>sp|O14782|KIF3C_HUMAN Kinesin-like protein KIF3C
Length = 793
Score = 60.8 bits (146), Expect = 2e-09
Identities = 41/165 (24%), Positives = 77/165 (46%), Gaps = 6/165 (3%)
Frame = +3
Query: 9 VVIDENGVERRIRKPKKIRSDKISKQR---LAEIERSIDENRRKLEQQKDMVAEEKDRVQ 179
V +E+ R P+ I + K L E + ++E + ++ + +V+EEK ++
Sbjct: 431 VAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKL- 489
Query: 180 QDLVEKENKLAKARQEQQ---MLRNRMTDLQRKIIVGGXXXXXXXXXXXXXXXXXXXXXX 350
L EKE L R+EQQ +L + ++ K+++GG
Sbjct: 490 --LEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIA 547
Query: 351 HHKQTEVDMRKKLQEKEEERMNIEVQYNSLQDEAADKKKRVKKIH 485
K+ E +M++++ ++EE M + Y SLQ E K K++KK++
Sbjct: 548 EQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLY 592
>sp|O55165|KIF3C_RAT Kinesin-like protein KIF3C
Length = 796
Score = 58.9 bits (141), Expect = 6e-09
Identities = 38/159 (23%), Positives = 76/159 (47%), Gaps = 3/159 (1%)
Frame = +3
Query: 18 DENGVERRIRKPKKIRSDKISKQRLAEIERSIDENRRKLEQQKDMVAEEKDRVQQDLVEK 197
D N R + + +K + L E + ++E + ++ + +V+EEK ++ L EK
Sbjct: 439 DNNNNHRPPQPTLEAALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKL---LEEK 495
Query: 198 ENKLAKARQEQQ---MLRNRMTDLQRKIIVGGXXXXXXXXXXXXXXXXXXXXXXHHKQTE 368
E L ++EQQ +L + ++ K+++GG K+ E
Sbjct: 496 EKMLEDLKREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRRE 555
Query: 369 VDMRKKLQEKEEERMNIEVQYNSLQDEAADKKKRVKKIH 485
+M++++ ++EE M + Y+SLQ E K K++KK++
Sbjct: 556 REMQQEMLLRDEETMELRGTYSSLQQEVEVKTKKLKKLY 594
>sp|O35066|KIF3C_MOUSE Kinesin-like protein KIF3C
Length = 796
Score = 58.2 bits (139), Expect = 1e-08
Identities = 32/135 (23%), Positives = 69/135 (51%)
Frame = +3
Query: 81 KQRLAEIERSIDENRRKLEQQKDMVAEEKDRVQQDLVEKENKLAKARQEQQMLRNRMTDL 260
K+RL E + +I ++R + ++K + EEK+++ +DL + +Q ++L + +
Sbjct: 467 KERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDL-------RREQQATELLAAKYKAM 519
Query: 261 QRKIIVGGXXXXXXXXXXXXXXXXXXXXXXHHKQTEVDMRKKLQEKEEERMNIEVQYNSL 440
+ K+++GG K+ E +M++++ ++EE M + Y+SL
Sbjct: 520 ESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMLVRDEETMELRGTYSSL 579
Query: 441 QDEAADKKKRVKKIH 485
Q E K K++KK++
Sbjct: 580 QQEVEVKTKKLKKLY 594
>sp|O15066|KIF3B_HUMAN Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin
motor 3B) (HH0048)
Length = 747
Score = 56.6 bits (135), Expect = 3e-08
Identities = 34/132 (25%), Positives = 69/132 (52%), Gaps = 3/132 (2%)
Frame = +3
Query: 96 EIERSIDENRRKLEQQKDMVAEEKDRVQQDLVEKENKLAKARQEQ---QMLRNRMTDLQR 266
E + ++ +R + + +VAEEK R+ L EKE K+ R+E+ +ML ++ ++
Sbjct: 416 EQQEKLEIEKRAIVEDHSLVAEEKMRL---LKEKEKKMEDLRREKDAAEMLGAKIKAMES 472
Query: 267 KIIVGGXXXXXXXXXXXXXXXXXXXXXXHHKQTEVDMRKKLQEKEEERMNIEVQYNSLQD 446
K++VGG K+ E +++++++ ++EE + ++ Y+SLQ
Sbjct: 473 KLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQ 532
Query: 447 EAADKKKRVKKI 482
E K K++KK+
Sbjct: 533 EVDIKTKKLKKL 544
Score = 29.3 bits (64), Expect = 5.3
Identities = 22/91 (24%), Positives = 46/91 (50%), Gaps = 3/91 (3%)
Frame = +3
Query: 12 VIDENGVERRIRKPKKIRSDKISKQRLAEIERSIDENRRKLEQQKDMVAEEKDR---VQQ 182
++D +++I + K+ Q +AE +R E ++++E + + E K+ +QQ
Sbjct: 481 IVDHTNEQQKILEQKR--------QEIAEQKRREREIQQQMESRDEETLELKETYSSLQQ 532
Query: 183 DLVEKENKLAKARQEQQMLRNRMTDLQRKII 275
++ K KL K + Q ++ + DLQ + I
Sbjct: 533 EVDIKTKKLKKLFSKLQAVKAEIHDLQEEHI 563
>sp|Q61771|KIF3B_MOUSE Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin
motor 3B)
Length = 747
Score = 56.2 bits (134), Expect = 4e-08
Identities = 34/132 (25%), Positives = 68/132 (51%), Gaps = 3/132 (2%)
Frame = +3
Query: 96 EIERSIDENRRKLEQQKDMVAEEKDRVQQDLVEKENKLAKARQEQ---QMLRNRMTDLQR 266
E + ++ +R + + +VAEEK R+ L EKE K+ R+E+ +ML ++ ++
Sbjct: 416 EQQEKLEIEKRAIVEDHSLVAEEKMRL---LKEKEKKMEDLRREKDAAEMLGAKIKAMES 472
Query: 267 KIIVGGXXXXXXXXXXXXXXXXXXXXXXHHKQTEVDMRKKLQEKEEERMNIEVQYNSLQD 446
K++VGG K+ E +++++++ ++EE + ++ Y SLQ
Sbjct: 473 KLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYTSLQQ 532
Query: 447 EAADKKKRVKKI 482
E K K++KK+
Sbjct: 533 EVDIKTKKLKKL 544
Score = 29.3 bits (64), Expect = 5.3
Identities = 22/91 (24%), Positives = 46/91 (50%), Gaps = 3/91 (3%)
Frame = +3
Query: 12 VIDENGVERRIRKPKKIRSDKISKQRLAEIERSIDENRRKLEQQKDMVAEEKDR---VQQ 182
++D +++I + K+ Q +AE +R E ++++E + + E K+ +QQ
Sbjct: 481 IVDHTNEQQKILEQKR--------QEIAEQKRREREIQQQMESRDEETLELKETYTSLQQ 532
Query: 183 DLVEKENKLAKARQEQQMLRNRMTDLQRKII 275
++ K KL K + Q ++ + DLQ + I
Sbjct: 533 EVDIKTKKLKKLFSKLQAVKAEIHDLQEEHI 563
>sp|P46869|FLA10_CHLRE Kinesin-like protein FLA10 (KHP1 protein)
Length = 786
Score = 46.6 bits (109), Expect = 3e-05
Identities = 26/130 (20%), Positives = 63/130 (48%)
Frame = +3
Query: 105 RSIDENRRKLEQQKDMVAEEKDRVQQDLVEKENKLAKARQEQQMLRNRMTDLQRKIIVGG 284
++I +++ K E QK + + ++ + K +QE+ +L +R+ +++ KI+VGG
Sbjct: 457 QAIIDDQGKTEAQKKAARDALKKQAEEARAIAGAIEKEKQEKAVLESRIKEMEGKIVVGG 516
Query: 285 XXXXXXXXXXXXXXXXXXXXXXHHKQTEVDMRKKLQEKEEERMNIEVQYNSLQDEAADKK 464
K+ E + +++L+E + +++ + ++ SL +E K
Sbjct: 517 VNMLEKVDELKQKSEDIKREAAIRKRQEEEAKRRLEELQAAQVDADAKFASLDEEINVKS 576
Query: 465 KRVKKIHNIY 494
+++KK+ Y
Sbjct: 577 RQLKKLFEKY 586
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,244,443
Number of Sequences: 369166
Number of extensions: 719993
Number of successful extensions: 6409
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4919
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6081
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3069744620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)