Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_028_L12 (237 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8H6Q0|DEF2_PETHY Floral defensin-like protein 2 precurs... 29 3.9 sp|O70326|GREM1_MOUSE Gremlin-1 precursor (Cysteine knot su... 28 6.6 sp|Q8WNY1|GREM1_MACMU Gremlin-1 precursor >gi|62510668|sp|O... 28 6.6 sp|O73755|GREM1_CHICK Gremlin-1 precursor 28 6.6 sp|O35793|GREM1_RAT Gremlin-1 precursor (Cysteine knot supe... 28 6.6 sp|O88508|DNM3A_MOUSE DNA (cytosine-5)-methyltransferase 3A... 28 6.6 sp|Q9Y6K1|DNM3A_HUMAN DNA (cytosine-5)-methyltransferase 3A... 28 6.6
>sp|Q8H6Q0|DEF2_PETHY Floral defensin-like protein 2 precursor (PhD2) Length = 101 Score = 28.9 bits (63), Expect = 3.9 Identities = 14/48 (29%), Positives = 24/48 (50%), Gaps = 6/48 (12%) Frame = +1 Query: 37 SEAGRCRDKCR------LNQEICIRACNLNRPPNRFCFGNCVRNNSRC 162 +EAG C+ +C +N+ C++ C P +F G+C + RC Sbjct: 23 TEAGTCKAECPTWEGICINKAPCVKCCKAQ--PEKFTDGHCSKILRRC 68
>sp|O70326|GREM1_MOUSE Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Down-regulated in Mos-transformed cells protein) Length = 184 Score = 28.1 bits (61), Expect = 6.6 Identities = 14/32 (43%), Positives = 16/32 (50%), Gaps = 3/32 (9%) Frame = +1 Query: 55 RDKCR---LNQEICIRACNLNRPPNRFCFGNC 141 RD C+ L Q I CN NRFC+G C Sbjct: 91 RDWCKTQPLKQTIHEEGCNSRTIINRFCYGQC 122
>sp|Q8WNY1|GREM1_MACMU Gremlin-1 precursor sp|O60565|GREM1_HUMAN Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Proliferation-inducing gene 2 protein) (Increased in high glucose-2 protein) (IHG-2) (Down-regulated in Mos-transformed cells protein) Length = 184 Score = 28.1 bits (61), Expect = 6.6 Identities = 14/32 (43%), Positives = 16/32 (50%), Gaps = 3/32 (9%) Frame = +1 Query: 55 RDKCR---LNQEICIRACNLNRPPNRFCFGNC 141 RD C+ L Q I CN NRFC+G C Sbjct: 91 RDWCKTQPLKQTIHEEGCNSRTIINRFCYGQC 122
>sp|O73755|GREM1_CHICK Gremlin-1 precursor Length = 184 Score = 28.1 bits (61), Expect = 6.6 Identities = 14/32 (43%), Positives = 16/32 (50%), Gaps = 3/32 (9%) Frame = +1 Query: 55 RDKCR---LNQEICIRACNLNRPPNRFCFGNC 141 RD C+ L Q I CN NRFC+G C Sbjct: 91 RDWCKTQPLKQTIHEEGCNSRTIINRFCYGQC 122
>sp|O35793|GREM1_RAT Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Down-regulated in Mos-transformed cells protein) Length = 184 Score = 28.1 bits (61), Expect = 6.6 Identities = 14/32 (43%), Positives = 16/32 (50%), Gaps = 3/32 (9%) Frame = +1 Query: 55 RDKCR---LNQEICIRACNLNRPPNRFCFGNC 141 RD C+ L Q I CN NRFC+G C Sbjct: 91 RDWCKTQPLKQTIHEEGCNSRTIINRFCYGQC 122
>sp|O88508|DNM3A_MOUSE DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA) Length = 908 Score = 28.1 bits (61), Expect = 6.6 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 1/41 (2%) Frame = +1 Query: 55 RDKCRLNQEICIRACNLNRPPNRFCF-GNCVRNNSRCFLLC 174 R KCR ++ICI +LN F G +N CFL C Sbjct: 480 RQKCRNIEDICISCGSLNVTLEHPLFIGGMCQNCKNCFLEC 520
>sp|Q9Y6K1|DNM3A_HUMAN DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA) Length = 909 Score = 28.1 bits (61), Expect = 6.6 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 1/41 (2%) Frame = +1 Query: 55 RDKCRLNQEICIRACNLNRPPNRFCF-GNCVRNNSRCFLLC 174 R KCR ++ICI +LN F G +N CFL C Sbjct: 481 RQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLEC 521
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,538,429 Number of Sequences: 369166 Number of extensions: 352457 Number of successful extensions: 944 Number of sequences better than 10.0: 7 Number of HSP's better than 10.0 without gapping: 931 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 944 length of database: 68,354,980 effective HSP length: 49 effective length of database: 59,302,965 effective search space used: 1719785985 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)