Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_J18
(879 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD4... 60 1e-08
sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 (CD4... 59 2e-08
sp|P58301|RAD50_PYRFU DNA double-strand break repair rad50 ... 52 2e-06
sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (Endosome-ass... 51 4e-06
sp|P23731|IFEB_ASCSU Intermediate filament protein B (IF-B) 51 4e-06
sp|Q9QYE6|GOGA5_MOUSE Golgin subfamily A member 5 (Sumiko p... 51 4e-06
sp|Q59037|SMC_METJA Chromosome partition protein smc homolog 51 5e-06
sp|Q8TBA6|GOGA5_HUMAN Golgin subfamily A member 5 (Golgin-8... 50 8e-06
sp|P59242|CING_MOUSE Cingulin 50 8e-06
sp|O00463|TRAF5_HUMAN TNF receptor-associated factor 5 (RIN... 49 2e-05
>sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD40 receptor associated factor
1) (CRAF1) (CD40 binding protein) (CD40BP) (LMP1
associated protein) (LAP1) (CAP-1)
Length = 568
Score = 59.7 bits (143), Expect = 1e-08
Identities = 63/256 (24%), Positives = 116/256 (45%), Gaps = 22/256 (8%)
Frame = +2
Query: 164 VICPEENCNLEFSLR-QLKDHLRMCDNSKSACLFHDLGCGESKISKEEALEHFTSYNEVH 340
V CP + C+++ LR +L HL C N+ S C F GC + + ++ H S H
Sbjct: 202 VSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRYGC-VFQGTNQQIKAHEASSAVQH 259
Query: 341 SKLMLDLINNIKNEMKDIEKKNRLEIEATKQQLIESQETLHQTLGNFVGYRNEIDELKRN 520
L+ + N+++ ++ ++ ++ +E K S ++LH + +F E+ RN
Sbjct: 260 VNLLKEWSNSLEKKVSLLQNES---VEKNK-----SIQSLHNQICSFEIEIERQKEMLRN 311
Query: 521 LTRK--------DEQISTMKQNLEKEIREIRQRNNDRDENVQMRKTLSQLEVENQTLQRR 676
K D Q +K+ L+KEIR RQ + D ++L E +++ +
Sbjct: 312 NESKILHLQRVIDSQAEKLKE-LDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKS 370
Query: 677 VDQILRDQQNMKAEVDKSTKNLGV-QLLLMDMKI-FNVENT------FVWKISNLSQHK- 829
Q+ R+ +++++ + + L V + L DM + F V T +WKI + + K
Sbjct: 371 AGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQ 430
Query: 830 ----GKNSIIWSDYFY 865
GK ++S FY
Sbjct: 431 EAVMGKTLSLYSQPFY 446
>sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 (CD40 receptor associated factor
1) (CRAF1) (TRAFAMN)
Length = 567
Score = 58.9 bits (141), Expect = 2e-08
Identities = 63/256 (24%), Positives = 115/256 (44%), Gaps = 22/256 (8%)
Frame = +2
Query: 164 VICPEENCNLEFSLR-QLKDHLRMCDNSKSACLFHDLGCGESKISKEEALEHFTSYNEVH 340
V CP + C+++ LR +L HL C N+ S C F GC + + ++ H S H
Sbjct: 201 VSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRYGC-VFQGTNQQIKAHEASSAVQH 258
Query: 341 SKLMLDLINNIKNEMKDIEKKNRLEIEATKQQLIESQETLHQTLGNFVGYRNEIDELKRN 520
L+ + N+++ ++ ++ ++ +E K S ++LH + +F E+ RN
Sbjct: 259 VNLLKEWSNSLEKKVSLLQNES---VEKNK-----SIQSLHNQICSFEIEIERQKEMLRN 310
Query: 521 LTRK--------DEQISTMKQNLEKEIREIRQRNNDRDENVQMRKTLSQLEVENQTLQRR 676
K D Q +K+ L+KEIR RQ + D ++L E +++ +
Sbjct: 311 NESKILHLQRVIDSQAEKLKE-LDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKS 369
Query: 677 VDQILRDQQNMKAEVDKSTKNLGV-QLLLMDMKI-FNVENT------FVWKISNLSQHK- 829
Q R+ +++++ + + L V + L DM + F V T +WKI + + K
Sbjct: 370 AGQAARNTGLLESQLSRHDQTLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQ 429
Query: 830 ----GKNSIIWSDYFY 865
GK ++S FY
Sbjct: 430 EAVMGKTLSLYSQPFY 445
>sp|P58301|RAD50_PYRFU DNA double-strand break repair rad50 ATPase
Length = 882
Score = 52.4 bits (124), Expect = 2e-06
Identities = 46/189 (24%), Positives = 95/189 (50%), Gaps = 8/189 (4%)
Frame = +2
Query: 176 EENCNLEFSLRQLKDHLRMCD--NSKSACLFHDLGCGESKISKEEALEHFTSYNEVHSKL 349
EE LE +R L + L+ K A L H + + ++E E T K
Sbjct: 535 EELRTLEGRIRGLAEDLKKLAPLEKKLAALIH-----KKQELEKELKELNTKLESFGFKS 589
Query: 350 MLDLINNIKNEMKDIEKK------NRLEIEATKQQLIESQETLHQTLGNFVGYRNEIDEL 511
+ DL + ++ E+++I K+ ++ E+E T++++ +++ETL + E+ E+
Sbjct: 590 VEDLDSKLR-ELEEIYKRYLTLLNSKKELEITQREIAKAKETLEMSF-------EELAEV 641
Query: 512 KRNLTRKDEQISTMKQNLEKEIREIRQRNNDRDENVQMRKTLSQLEVENQTLQRRVDQIL 691
+ ++ R ++++S +KQ +E + R+E ++ K L++LE + + L++R D I
Sbjct: 642 EADIERIEKKLSQLKQKYNEE-----EYKKKREEKEELEKELARLEAQKKELEKRRDTIK 696
Query: 692 RDQQNMKAE 718
+ +KAE
Sbjct: 697 STLEKLKAE 705
>sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (Endosome-associated protein p162) (Zinc
finger FYVE domain-containing protein 2)
Length = 1411
Score = 51.2 bits (121), Expect = 4e-06
Identities = 47/239 (19%), Positives = 109/239 (45%), Gaps = 12/239 (5%)
Frame = +2
Query: 74 GTSDDCVQEPLSKIDIVVDHVS--IKKISLLKVICPEENCNLEFSLRQLKDHLRMCDNSK 247
G + ++E LS+++ H+ K++ + + L+ + QL H ++ + +
Sbjct: 371 GEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQL--HSKLLETER 428
Query: 248 SACLFHDLGCGESKISKEEALEHFTSYNEVHSKLMLDLINNIKNEMKD-IEKKNRLE--I 418
H + ++S E+ ++ ++ KL + ++ ++K+ + L+ +
Sbjct: 429 QLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKL-----SRLEEQLKEKVTNSTELQHQL 483
Query: 419 EATKQQLIESQETLHQTLGNFVGYRNEIDELKRNLTRKDEQISTMKQNLEKEIREIRQRN 598
+ TKQQ E Q T +N+++++ R + KD++I ++ L+K I
Sbjct: 484 DKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLE 543
Query: 599 NDRDE---NVQMRK----TLSQLEVENQTLQRRVDQILRDQQNMKAEVDKSTKNLGVQL 754
+R++ +Q + L+QL+ +N TLQ +V Q+ +N ++ +NL Q+
Sbjct: 544 KEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQV 602
Score = 45.4 bits (106), Expect = 2e-04
Identities = 44/200 (22%), Positives = 93/200 (46%), Gaps = 9/200 (4%)
Frame = +2
Query: 140 IKKISLLKVICPEENCNLEFSLRQLKDHLRMCDNSKSACLFHDLGCGESKISKEEALEHF 319
++K+ + K E ++ L ++ D L+ NSKS F E++ K L+
Sbjct: 841 LQKVKMEKEALMTELSTVKDKLSKVSDSLK---NSKSE--FEK----ENQKGKAAILDLE 891
Query: 320 TSYNEVHSKLMLDLINNIKNEM---KDIEKKN------RLEIEATKQQLIESQETLHQTL 472
+ E+ +L + + N +K + K +EK+ +LE+ + ++QLI++Q TL Q
Sbjct: 892 KTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNE 951
Query: 473 GNFVGYRNEIDELKRNLTRKDEQISTMKQNLEKEIREIRQRNNDRDENVQMRKTLSQLEV 652
+ I+ELK++ +K +QI ++ L+ + + + N + Q+ + +L
Sbjct: 952 KEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQ--QLTQAAQELAA 1009
Query: 653 ENQTLQRRVDQILRDQQNMK 712
E + + + + Q+ K
Sbjct: 1010 EKEKISVLQNNYEKSQETFK 1029
Score = 38.1 bits (87), Expect = 0.033
Identities = 59/283 (20%), Positives = 119/283 (42%), Gaps = 50/283 (17%)
Frame = +2
Query: 95 QEPLSKIDIVVDHVSIKKISLLKVICPEENCN-LEFSLRQLKDHL----RMCDNSKSACL 259
Q+ L+KI +D V+ K +E+C+ LE L++ K+ + + +
Sbjct: 680 QQELNKITTQLDQVTAKLQD------KQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIK 733
Query: 260 FHDLGCGESKISKEEALEHFTSYNEVHSKLML---DLINNIKNEMK-------DIEKKNR 409
+ E K SKE+AL+ ++++ L L +L ++ E + D++KK+
Sbjct: 734 KLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSE 793
Query: 410 LEIEATKQQLIE---------------SQETL--HQTLGNFV---------------GYR 493
+E+ KQ+L + SQET H+ L N +
Sbjct: 794 A-LESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALM 852
Query: 494 NEIDELKRNLTRKDEQISTMKQNLEKEIREIRQRNNDRDENVQMRKTLSQLEVENQTLQR 673
E+ +K L++ + + K EKE + + + KT +L+ LQ
Sbjct: 853 TELSTVKDKLSKVSDSLKNSKSEFEKE------NQKGKAAILDLEKTCKELK---HQLQV 903
Query: 674 RVDQILRDQQNMKAEVDK---STKNLGVQLLLMDMKIFNVENT 793
+++ L++Q+ +K ++K ++ L ++L M ++ +NT
Sbjct: 904 QMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNT 946
Score = 34.3 bits (77), Expect = 0.47
Identities = 32/144 (22%), Positives = 68/144 (47%), Gaps = 3/144 (2%)
Frame = +2
Query: 413 EIEATKQQLIESQETLHQTLGNFVGYRNEIDELKRNLTRKDEQISTMKQNLEKEIREIRQ 592
E+ AT+Q L +E L + + RN+I N + +++ T K LE++ + Q
Sbjct: 1041 ELLATRQDLKSVEEKLSLAQEDLISNRNQIG----NQNKLIQELKTAKATLEQDSAKKEQ 1096
Query: 593 RNNDRD---ENVQMRKTLSQLEVENQTLQRRVDQILRDQQNMKAEVDKSTKNLGVQLLLM 763
+ +R +++Q K+L + E+ N+ + ++ +I + + E+ K + L L
Sbjct: 1097 QLQERCKALQDIQKEKSLKEKELVNE--KSKLAEIEEIKCRQEKEITKLNEELKSHKLES 1154
Query: 764 DMKIFNVENTFVWKISNLSQHKGK 835
+I N+++ I + +GK
Sbjct: 1155 IKEITNLKDAKQLLIQQKLELQGK 1178
>sp|P23731|IFEB_ASCSU Intermediate filament protein B (IF-B)
Length = 589
Score = 51.2 bits (121), Expect = 4e-06
Identities = 45/183 (24%), Positives = 84/183 (45%), Gaps = 8/183 (4%)
Frame = +2
Query: 320 TSYNEVHSKLMLDLINNIKNEMKDIEKKNRL---EIEATKQQLIESQETLHQTLGNFVGY 490
+SY K M D I +++ ++ D+E KN L E++ QL + Q L +
Sbjct: 331 SSYQREEVKRMRDNIGDLRGKLGDLEAKNALLEKEVQNLNYQLNDDQRQYEAALNDRDAT 390
Query: 491 RNEIDELKRNLTRKDEQISTMKQNLEKEIREIRQRNNDRDENVQMRKTLSQLEVENQTLQ 670
+ E + L + + + KQ L+ EI R+ + V +R+ + Q+ V+ +LQ
Sbjct: 391 LRRMREECQTLVAELQALLDTKQMLDAEIAIYRKMLEGEESRVGLRQMVEQV-VKTHSLQ 449
Query: 671 RRVD----QILRDQQNMKAEVDKSTK-NLGVQLLLMDMKIFNVENTFVWKISNLSQHKGK 835
++ D + +R + + K +S K N+ + + K +ENT K NL +H+ K
Sbjct: 450 QQEDTDSTRNVRGEVSTKTTFQRSAKGNVTISECDPNGKFITLENTHRSKDENLGEHRLK 509
Query: 836 NSI 844
+
Sbjct: 510 RKL 512
>sp|Q9QYE6|GOGA5_MOUSE Golgin subfamily A member 5 (Sumiko protein) (Ret-II protein)
Length = 729
Score = 51.2 bits (121), Expect = 4e-06
Identities = 40/202 (19%), Positives = 94/202 (46%), Gaps = 7/202 (3%)
Frame = +2
Query: 206 RQLKDHLRMCDNSKSACLFHDLGCGESKISKEEALEHFTSYNEVHSKLMLDLINNIKNEM 385
R L+ ++ ++ K F L + + E L H + + ++ ++ +++E+
Sbjct: 435 RILQSKEKLINSLKEGSSFEGLESSTASSMELEELRHEKEMQKEEIQKLMGQMHQLRSEL 494
Query: 386 KDIEKKNRLEIEATKQQLIESQETLHQTLGNFVGYRNEIDELKRNLTRKDEQISTMKQNL 565
+D+E + E E+ ++QL + Q+ + + R EL+ L R ++ M+++L
Sbjct: 495 QDMEAQQVSEAESAREQLQDLQDQIAK-------QRTSKQELETELERMKQEFRYMEEDL 547
Query: 566 EKEIREIRQRNNDRDENVQ-MRKTLSQLEVENQT---LQRRVDQI---LRDQQNMKAEVD 724
+ ++ R DR+E +Q +R L+ + N + L+ R+ Q+ L +Q M +
Sbjct: 548 HRTKNTLQSRIKDREEEIQKLRNQLTNKTLSNSSQSELESRLHQLTETLIQKQTMLESLS 607
Query: 725 KSTKNLGVQLLLMDMKIFNVEN 790
+L QL ++ ++ + +
Sbjct: 608 TEKNSLVFQLERLEQQVHSASS 629
>sp|Q59037|SMC_METJA Chromosome partition protein smc homolog
Length = 1169
Score = 50.8 bits (120), Expect = 5e-06
Identities = 42/164 (25%), Positives = 81/164 (49%), Gaps = 10/164 (6%)
Frame = +2
Query: 281 ESKISKEEALEHFTSYNEVHSKLMLDLINNIKN---EMKDIEKKNRL--EIEATKQQLIE 445
E K EE L+ E+ + ++ NN+K E +D EK +L E++A K LI
Sbjct: 176 EKKKKAEEELKKARELIEMIDIRISEVENNLKKLKKEKEDAEKYIKLNEELKAAKYALIL 235
Query: 446 SQET-LHQTLGNFVGYRNEIDELKRNLTRK----DEQISTMKQNLEKEIREIRQRNNDRD 610
+ + L+ L N ++ELK K D +I +K L I E+ ++ N +
Sbjct: 236 KKVSYLNVLLENIQNDIKNLEELKNEFLSKVREIDVEIENLKLRLNNIINELNEKGN--E 293
Query: 611 ENVQMRKTLSQLEVENQTLQRRVDQILRDQQNMKAEVDKSTKNL 742
E +++ K++ +LEVE + ++ +D + + + ++ E++ K +
Sbjct: 294 EVLELHKSIKELEVEIENDKKVLDSSINELKKVEVEIENKKKEI 337
Score = 42.7 bits (99), Expect = 0.001
Identities = 56/240 (23%), Positives = 111/240 (46%), Gaps = 28/240 (11%)
Frame = +2
Query: 92 VQEPLSKIDIVVDHVSIKKISL---LKVICPEENCNLEFS------LRQL----KDHLRM 232
++E + ++ +V S KK+ + L++I E E + +++L KD L
Sbjct: 695 IKEEIERLSKIVKRSSAKKMEIENTLEIIKKNEMRKREIAEKNTIKIKELELKNKDILEE 754
Query: 233 CD--NSKSACLFHDLGCGESKISK--EEALEHFTSYNEVHSKLMLDLINNIKNEMKDIEK 400
+ N K + + + ESKI++ E + E S L +N I+ E+K +EK
Sbjct: 755 LEELNLKREEILNRINEIESKINELIERREKIINELKEYESDENLKRMNEIEGELKILEK 814
Query: 401 -----KNRLE--IEATKQQLIESQETLHQTLGNFVGYRNEIDELKRNLTRKDEQISTMKQ 559
KN ++ + K+ LI E L++ ++ EL ++ IS K+
Sbjct: 815 EKAKLKNEIDKGLTLVKEILIPKIEELNK----------KVSELINKKVILEKNISFYKE 864
Query: 560 NLEKEIREIRQRNNDRDENVQMRKTLS----QLEVENQTLQRRVDQILRDQQNMKAEVDK 727
++EK + + ++ +E + K L+ QLE E +TL+R +ILR ++++ +++
Sbjct: 865 SIEKNLSILEEKRKRYEELAKNLKELTEKKEQLEKEIETLERERREILRKVRDIENRINE 924
Score = 35.0 bits (79), Expect = 0.28
Identities = 46/226 (20%), Positives = 101/226 (44%), Gaps = 20/226 (8%)
Frame = +2
Query: 110 KIDIVVDHVSIKKISLLKVICP---EENCNLEFSLRQLKDHLRMCDNSKSACLFHDLGCG 280
+ID+ ++++ ++ +++ + EE L S+++L+ + +N K D
Sbjct: 268 EIDVEIENLKLRLNNIINELNEKGNEEVLELHKSIKELEVEI---ENDKKVL---DSSIN 321
Query: 281 ESKISKEEALEHFTSYNEVHSKLM--LDLINNIKNEMKDIEKKNR---LEIEATKQQLIE 445
E K + E E K++ D I + ++K+IE+K + E E K+ + E
Sbjct: 322 ELKKVEVEIENKKKEIKETQKKIIENRDSIIEKEQQIKEIEEKIKNLNYEKERLKEAIAE 381
Query: 446 SQ-------ETLHQTLGNFVGYRNEIDELKRNLTRKDEQISTMKQNLEKEIREIRQRNND 604
S+ E+ + +NE+ LK+ L D I+ +EK I++ +
Sbjct: 382 SESIIKHLKESEMEIADEIAKNQNELYRLKKELNDLDNLINRKNFEIEKNNEMIKKLKEE 441
Query: 605 RD--ENVQMRK---TLSQLEVENQTLQRRVDQILRDQQNMKAEVDK 727
+ E+V + L L VE + +R + ++ ++ ++A++D+
Sbjct: 442 LETVEDVDTKPLYLELENLNVEIEFSKRGIKELEEKKKELQAKLDE 487
>sp|Q8TBA6|GOGA5_HUMAN Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein)
(Ret-II protein)
Length = 731
Score = 50.1 bits (118), Expect = 8e-06
Identities = 45/199 (22%), Positives = 91/199 (45%), Gaps = 9/199 (4%)
Frame = +2
Query: 206 RQLKDHLRMCDNSKSACLFHDLGCGESKISKEEALEHFTSYNEVHSKLMLDLINNIKNEM 385
R L+ ++ ++ K F L + + E L H + ++ I+ +++E+
Sbjct: 437 RILQSKEKLINSLKEGSGFEGLDSSTASSMELEELRHEKEMQREEIQKLMGQIHQLRSEL 496
Query: 386 KDIEKKNRLEIEATKQQLIESQETLHQTLGNFVGYRNEIDELKRNLTRKDEQISTMKQNL 565
+D+E + E E+ ++QL + LH + G + EL+ L R ++ ++++L
Sbjct: 497 QDMEAQQVNEAESAREQL----QDLHDQI---AGQKASKQELETELERLKQEFHYIEEDL 549
Query: 566 EKEIREIRQRNNDRDENVQ------MRKTL---SQLEVENQTLQRRVDQILRDQQNMKAE 718
+ ++ R DRDE +Q KTL SQ E+EN+ Q + + L +Q M
Sbjct: 550 YRTKNTLQSRIKDRDEEIQKLRNQLTNKTLSNSSQSELENRLHQ--LTETLIQKQTMLES 607
Query: 719 VDKSTKNLGVQLLLMDMKI 775
+ +L QL ++ ++
Sbjct: 608 LSTEKNSLVFQLERLEQQM 626
>sp|P59242|CING_MOUSE Cingulin
Length = 1191
Score = 50.1 bits (118), Expect = 8e-06
Identities = 44/208 (21%), Positives = 92/208 (44%), Gaps = 15/208 (7%)
Frame = +2
Query: 176 EENCNLEFSLRQLKDHLRMCDNSKSACLFHDLGCGESKISKEEALEHFTSYNEVHSKLML 355
++N L+ +L+QL+ +K A + G+ + + E L N+ + +L
Sbjct: 669 QQNLQLQKTLQQLRQDCEEASKAKVASETEAMMLGQRRATVETTLRETQEENDEFRRRIL 728
Query: 356 DLINNIKN-----------EMKDIEKKNRLEIEATKQQLIESQETLHQTLGNFVGYRN-- 496
L +K E + +K +RLE+E KQQL E+ + GN +
Sbjct: 729 GLEQQLKEARGLAEGGEAVEARLRDKVHRLEVE--KQQLEEALNAAQEEEGNLAAAKRAL 786
Query: 497 --EIDELKRNLTRKDEQISTMKQNLEKEIREIRQRNNDRDENVQMRKTLSQLEVENQTLQ 670
+DE +R L R ++ + + LE+E + + +R++ ++LE + + L
Sbjct: 787 EVRLDEAQRGLARLGQEQQALNRALEEEGK----------QREALRRSKAELEEQKRLLN 836
Query: 671 RRVDQILRDQQNMKAEVDKSTKNLGVQL 754
R VD++ ++ + + + + + L Q+
Sbjct: 837 RTVDRLNKELEQIGDDSKLALQQLQAQM 864
Score = 44.3 bits (103), Expect = 5e-04
Identities = 41/167 (24%), Positives = 80/167 (47%), Gaps = 32/167 (19%)
Frame = +2
Query: 332 EVHSKLMLDLINNIKNEMKDIEK----------KNRLEIEATKQQLIE---SQETLHQTL 472
E + M L+ ++ E+++ + KN+ E+ ATKQ+L++ +E + + L
Sbjct: 532 EAERQKMSSLVRELQRELEETSEETGHWQSMFQKNKEELRATKQELLQLRMEKEEMEEEL 591
Query: 473 GNFVGYRNEIDELKRNLTRKDEQISTMKQNLEK---EIREIR--QRNND---RDENVQMR 628
G + E R TR Q+ +K+ L + E++E++ Q+N + R N +
Sbjct: 592 GEKMEVLQRDLEQARASTRDTHQVEELKKELRRTQGELKELQAEQQNQEVTGRHRNQVLE 651
Query: 629 KTLS----------QLEVENQTLQRRVDQILRD-QQNMKAEVDKSTK 736
K L+ +LE +N LQ+ + Q+ +D ++ KA+V T+
Sbjct: 652 KQLAALREEADRGRELEQQNLQLQKTLQQLRQDCEEASKAKVASETE 698
Score = 42.7 bits (99), Expect = 0.001
Identities = 33/132 (25%), Positives = 70/132 (53%), Gaps = 7/132 (5%)
Frame = +2
Query: 380 EMKDIEKK-NRLEIEATKQQLIESQETLHQTLGNFVGYRNEIDELKRNLTRKD---EQIS 547
++K +E+K +RLE E L E + T+ R+++D+L+ L ++ + +
Sbjct: 951 QLKSLEEKVSRLEAE-----LDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLE 1005
Query: 548 TMKQNLEKEIREIRQRNNDRDENVQMRKTLSQLEVENQTLQRRVDQILRDQ---QNMKAE 718
K +LE++ ++++ R + + +LSQLE +NQ LQ R+ R++ Q+ +
Sbjct: 1006 CDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRK 1065
Query: 719 VDKSTKNLGVQL 754
+++ K L +Q+
Sbjct: 1066 LERRVKELSIQI 1077
>sp|O00463|TRAF5_HUMAN TNF receptor-associated factor 5 (RING finger protein 84)
Length = 557
Score = 48.9 bits (115), Expect = 2e-05
Identities = 61/276 (22%), Positives = 115/276 (41%), Gaps = 22/276 (7%)
Frame = +2
Query: 110 KIDIVVDHVSIKKISLLK---VICPEENCNLEFSLRQLKDHLRMCDNSKSACLFHDLGCG 280
K D+VV ++ + +L V CP NC ++ +HL +C ++ C F GC
Sbjct: 172 KKDVVVINLQNHEENLCPEYPVFCPN-NCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCA 230
Query: 281 ESKISKEEALEHFTSYNEVHSKLMLDLINNIKNEMKDIEKKNRLEIEATK-QQLIESQET 457
+ + +H S H +L+L+ ++ ++ D+ K LE + +K QQL E+ +
Sbjct: 231 VTD-KRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKS--LEQKESKIQQLAETIKK 287
Query: 458 LHQTLGNFVGYRNEIDELKRNLTRKDEQISTMKQNLEKEIREIRQRNNDRDENVQMRKTL 637
L + F + N+ I LE ++ ++ Q N + +R +
Sbjct: 288 LEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAW-LEAQVHQLLQMVNQQQNKFDLRPLM 346
Query: 638 SQLEVENQ--TLQRRVDQ---ILRDQQNM--------KAEVDKSTKNLGVQLLLMDMKIF 778
++ Q TL DQ +L ++ N KA++ K+ + + L++ +
Sbjct: 347 EAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEE----RFKLLEGTCY 402
Query: 779 NVENTFVWKISNLSQHK-----GKNSIIWSDYFYDS 871
N +WK+++ K G I+S FY S
Sbjct: 403 N--GKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTS 436
Score = 32.3 bits (72), Expect = 1.8
Identities = 47/250 (18%), Positives = 103/250 (41%), Gaps = 20/250 (8%)
Frame = +2
Query: 8 CTCRFCLECIDQYLQ-DGDKMCPGTSDDCVQEPLSKIDIVVDHVSIKKISLLKVICPEE- 181
C RFC CI + + +CP +E + ++ D+ +++ L V C
Sbjct: 60 CGHRFCQHCILSLRELNTVPICPVD-----KEVIKSQEVFKDNCCKREVLNLYVYCSNAP 114
Query: 182 NCNLEFSLRQLKDHLRMCDNSKSACLFHDLGCGESK----ISKEEALEHFTSYNEVHSKL 349
CN + L + +DHL+ CLF + C K + +++ EH ++ + +
Sbjct: 115 GCNAKVILGRYQDHLQQ-------CLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEK 167
Query: 350 ML-----DLINNIKNEMKDIEKK------NRLEIEATKQQLIESQETLHQTLGN--FVGY 490
L ++ N++N +++ + N K ++ E + + F Y
Sbjct: 168 CLYCKKDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHY 227
Query: 491 RNEIDELKRNLTRKDEQISTMKQNLEKEIREIRQRNNDRDENV-QMRKTLSQLEVENQTL 667
+ + +RNL + + L + +R + ++N +E + + K+L Q E + Q L
Sbjct: 228 GCAVTDKRRNLQQHEHSA------LREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQL 281
Query: 668 QRRVDQILRD 697
+ ++ ++
Sbjct: 282 AETIKKLEKE 291
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,458,284
Number of Sequences: 369166
Number of extensions: 1868662
Number of successful extensions: 8912
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7666
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8715
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8742211660
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)