Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_028_J12 (323 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q99LI8|HGS_MOUSE Hepatocyte growth factor-regulated tyro... 61 7e-10 sp|O14964|HGS_HUMAN Hepatocyte growth factor-regulated tyro... 61 7e-10 sp|Q9JJ50|HGS_RAT Hepatocyte growth factor-regulated tyrosi... 61 7e-10 sp|Q960X8|HRS_DROME Hepatocyte growth factor-regulated tyro... 60 2e-09 sp|Q8IWB7|WDFY1_HUMAN WD repeat and FYVE domain containing ... 53 2e-07 sp|Q96P53|WDFY2_HUMAN WD repeat and FYVE domain containing ... 49 3e-06 sp|Q8BUB4|WDFY2_MOUSE WD repeat and FYVE domain containing ... 49 3e-06 sp|Q22712|YW91_CAEEL Hypothetical protein T24A11.1 in chrom... 46 2e-05 sp|Q8BL66|EEA1_MOUSE Early endosome antigen 1 45 5e-05 sp|Q13615|MTMR3_HUMAN Myotubularin-related protein 3 (FYVE ... 44 9e-05
>sp|Q99LI8|HGS_MOUSE Hepatocyte growth factor-regulated tyrosine kinase substrate Length = 775 Score = 61.2 bits (147), Expect = 7e-10 Identities = 25/35 (71%), Positives = 29/35 (82%) Frame = +2 Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESL 109 CG IFC +C++K S IPK+GIEKEVRVCE CYE L Sbjct: 185 CGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQL 219
>sp|O14964|HGS_HUMAN Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs) Length = 777 Score = 61.2 bits (147), Expect = 7e-10 Identities = 25/35 (71%), Positives = 29/35 (82%) Frame = +2 Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESL 109 CG IFC +C++K S IPK+GIEKEVRVCE CYE L Sbjct: 185 CGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQL 219
>sp|Q9JJ50|HGS_RAT Hepatocyte growth factor-regulated tyrosine kinase substrate (SNAP-25 interacting protein Hrs-2) Length = 776 Score = 61.2 bits (147), Expect = 7e-10 Identities = 25/35 (71%), Positives = 29/35 (82%) Frame = +2 Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESL 109 CG IFC +C++K S IPK+GIEKEVRVCE CYE L Sbjct: 185 CGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQL 219
>sp|Q960X8|HRS_DROME Hepatocyte growth factor-regulated tyrosine kinase substrate Length = 760 Score = 60.1 bits (144), Expect = 2e-09 Identities = 22/37 (59%), Positives = 30/37 (81%) Frame = +2 Query: 2 NCGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESLR 112 NCG +FC +CT K+ +PKYGIEKEVRVC+ C+ +L+ Sbjct: 182 NCGQVFCGQCTAKQCPLPKYGIEKEVRVCDGCFAALQ 218
>sp|Q8IWB7|WDFY1_HUMAN WD repeat and FYVE domain containing protein 1 (WD40- and FYVE-domain containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain containing protein 17) Length = 410 Score = 52.8 bits (125), Expect = 2e-07 Identities = 23/52 (44%), Positives = 33/52 (63%) Frame = +2 Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESLRGSDIHTGRITNQKGGH 160 CG C +C++KRS+ P G E +VRVC+SCY+S++ D T T +G H Sbjct: 317 CGQAVCGKCSSKRSSYPVMGFEFQVRVCDSCYDSIKDED-RTSLATFHEGKH 367
>sp|Q96P53|WDFY2_HUMAN WD repeat and FYVE domain containing protein 2 (WD40- and FYVE-domain containing protein 2) (Zinc finger FYVE domain containing protein 22) Length = 400 Score = 49.3 bits (116), Expect = 3e-06 Identities = 19/35 (54%), Positives = 27/35 (77%) Frame = +2 Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESL 109 CG C +C++KRS+IP G E EVRVC+SC+E++ Sbjct: 317 CGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAI 351
>sp|Q8BUB4|WDFY2_MOUSE WD repeat and FYVE domain containing protein 2 (WD40- and FYVE-domain containing protein 2) Length = 400 Score = 49.3 bits (116), Expect = 3e-06 Identities = 19/35 (54%), Positives = 27/35 (77%) Frame = +2 Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESL 109 CG C +C++KRS+IP G E EVRVC+SC+E++ Sbjct: 317 CGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAI 351
>sp|Q22712|YW91_CAEEL Hypothetical protein T24A11.1 in chromosome III Length = 938 Score = 46.2 bits (108), Expect = 2e-05 Identities = 16/48 (33%), Positives = 30/48 (62%) Frame = +2 Query: 2 NCGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESLRGSDIHTGRITN 145 NCG + C++C+ R ++ + G + R C+SCY+S+ +D+ R T+ Sbjct: 820 NCGRVVCEDCSKNRFSVIEEGKSVQKRACDSCYDSMHETDLKLSRATS 867
>sp|Q8BL66|EEA1_MOUSE Early endosome antigen 1 Length = 1411 Score = 45.1 bits (105), Expect = 5e-05 Identities = 19/37 (51%), Positives = 26/37 (70%) Frame = +2 Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESLRG 115 CGNIFC EC+TK + P +K VRVC++C+ L+G Sbjct: 1377 CGNIFCAECSTKNALTP--SSKKPVRVCDACFNDLQG 1411
>sp|Q13615|MTMR3_HUMAN Myotubularin-related protein 3 (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain containing protein 10) Length = 1198 Score = 44.3 bits (103), Expect = 9e-05 Identities = 16/36 (44%), Positives = 23/36 (63%) Frame = +2 Query: 2 NCGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESL 109 NCGN+FC C ++ +P + + RVC+SCY SL Sbjct: 1143 NCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSL 1178
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,925,691 Number of Sequences: 369166 Number of extensions: 424600 Number of successful extensions: 1255 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1232 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1247 length of database: 68,354,980 effective HSP length: 76 effective length of database: 54,315,120 effective search space used: 1683768720 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)