Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_J12
(323 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99LI8|HGS_MOUSE Hepatocyte growth factor-regulated tyro... 61 7e-10
sp|O14964|HGS_HUMAN Hepatocyte growth factor-regulated tyro... 61 7e-10
sp|Q9JJ50|HGS_RAT Hepatocyte growth factor-regulated tyrosi... 61 7e-10
sp|Q960X8|HRS_DROME Hepatocyte growth factor-regulated tyro... 60 2e-09
sp|Q8IWB7|WDFY1_HUMAN WD repeat and FYVE domain containing ... 53 2e-07
sp|Q96P53|WDFY2_HUMAN WD repeat and FYVE domain containing ... 49 3e-06
sp|Q8BUB4|WDFY2_MOUSE WD repeat and FYVE domain containing ... 49 3e-06
sp|Q22712|YW91_CAEEL Hypothetical protein T24A11.1 in chrom... 46 2e-05
sp|Q8BL66|EEA1_MOUSE Early endosome antigen 1 45 5e-05
sp|Q13615|MTMR3_HUMAN Myotubularin-related protein 3 (FYVE ... 44 9e-05
>sp|Q99LI8|HGS_MOUSE Hepatocyte growth factor-regulated tyrosine kinase substrate
Length = 775
Score = 61.2 bits (147), Expect = 7e-10
Identities = 25/35 (71%), Positives = 29/35 (82%)
Frame = +2
Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESL 109
CG IFC +C++K S IPK+GIEKEVRVCE CYE L
Sbjct: 185 CGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQL 219
>sp|O14964|HGS_HUMAN Hepatocyte growth factor-regulated tyrosine kinase substrate
(Protein pp110) (Hrs)
Length = 777
Score = 61.2 bits (147), Expect = 7e-10
Identities = 25/35 (71%), Positives = 29/35 (82%)
Frame = +2
Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESL 109
CG IFC +C++K S IPK+GIEKEVRVCE CYE L
Sbjct: 185 CGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQL 219
>sp|Q9JJ50|HGS_RAT Hepatocyte growth factor-regulated tyrosine kinase substrate
(SNAP-25 interacting protein Hrs-2)
Length = 776
Score = 61.2 bits (147), Expect = 7e-10
Identities = 25/35 (71%), Positives = 29/35 (82%)
Frame = +2
Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESL 109
CG IFC +C++K S IPK+GIEKEVRVCE CYE L
Sbjct: 185 CGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQL 219
>sp|Q960X8|HRS_DROME Hepatocyte growth factor-regulated tyrosine kinase substrate
Length = 760
Score = 60.1 bits (144), Expect = 2e-09
Identities = 22/37 (59%), Positives = 30/37 (81%)
Frame = +2
Query: 2 NCGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESLR 112
NCG +FC +CT K+ +PKYGIEKEVRVC+ C+ +L+
Sbjct: 182 NCGQVFCGQCTAKQCPLPKYGIEKEVRVCDGCFAALQ 218
>sp|Q8IWB7|WDFY1_HUMAN WD repeat and FYVE domain containing protein 1 (WD40- and
FYVE-domain containing protein 1)
(Phosphoinositide-binding protein 1) (FENS-1) (Zinc
finger FYVE domain containing protein 17)
Length = 410
Score = 52.8 bits (125), Expect = 2e-07
Identities = 23/52 (44%), Positives = 33/52 (63%)
Frame = +2
Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESLRGSDIHTGRITNQKGGH 160
CG C +C++KRS+ P G E +VRVC+SCY+S++ D T T +G H
Sbjct: 317 CGQAVCGKCSSKRSSYPVMGFEFQVRVCDSCYDSIKDED-RTSLATFHEGKH 367
>sp|Q96P53|WDFY2_HUMAN WD repeat and FYVE domain containing protein 2 (WD40- and
FYVE-domain containing protein 2) (Zinc finger FYVE
domain containing protein 22)
Length = 400
Score = 49.3 bits (116), Expect = 3e-06
Identities = 19/35 (54%), Positives = 27/35 (77%)
Frame = +2
Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESL 109
CG C +C++KRS+IP G E EVRVC+SC+E++
Sbjct: 317 CGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAI 351
>sp|Q8BUB4|WDFY2_MOUSE WD repeat and FYVE domain containing protein 2 (WD40- and
FYVE-domain containing protein 2)
Length = 400
Score = 49.3 bits (116), Expect = 3e-06
Identities = 19/35 (54%), Positives = 27/35 (77%)
Frame = +2
Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESL 109
CG C +C++KRS+IP G E EVRVC+SC+E++
Sbjct: 317 CGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAI 351
>sp|Q22712|YW91_CAEEL Hypothetical protein T24A11.1 in chromosome III
Length = 938
Score = 46.2 bits (108), Expect = 2e-05
Identities = 16/48 (33%), Positives = 30/48 (62%)
Frame = +2
Query: 2 NCGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESLRGSDIHTGRITN 145
NCG + C++C+ R ++ + G + R C+SCY+S+ +D+ R T+
Sbjct: 820 NCGRVVCEDCSKNRFSVIEEGKSVQKRACDSCYDSMHETDLKLSRATS 867
>sp|Q8BL66|EEA1_MOUSE Early endosome antigen 1
Length = 1411
Score = 45.1 bits (105), Expect = 5e-05
Identities = 19/37 (51%), Positives = 26/37 (70%)
Frame = +2
Query: 5 CGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESLRG 115
CGNIFC EC+TK + P +K VRVC++C+ L+G
Sbjct: 1377 CGNIFCAECSTKNALTP--SSKKPVRVCDACFNDLQG 1411
>sp|Q13615|MTMR3_HUMAN Myotubularin-related protein 3 (FYVE domain-containing dual
specificity protein phosphatase 1) (FYVE-DSP1) (Zinc
finger FYVE domain containing protein 10)
Length = 1198
Score = 44.3 bits (103), Expect = 9e-05
Identities = 16/36 (44%), Positives = 23/36 (63%)
Frame = +2
Query: 2 NCGNIFCDECTTKRSNIPKYGIEKEVRVCESCYESL 109
NCGN+FC C ++ +P + + RVC+SCY SL
Sbjct: 1143 NCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSL 1178
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,925,691
Number of Sequences: 369166
Number of extensions: 424600
Number of successful extensions: 1255
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1232
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1247
length of database: 68,354,980
effective HSP length: 76
effective length of database: 54,315,120
effective search space used: 1683768720
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)