Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_I18
(882 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8V439|R1AB_CVBLU Replicase polyprotein 1ab (pp1ab) (ORF... 33 1.1
sp|Q91A29|R1AB_CVBEN Replicase polyprotein 1ab (pp1ab) (ORF... 33 1.4
sp|Q66198|R1AB_CVBM Replicase polyprotein 1ab (pp1ab) (ORF1... 33 1.4
sp|Q8V6W7|R1AB_CVBQ Replicase polyprotein 1ab (pp1ab) (ORF1... 33 1.4
sp|Q8BFV3|DUS4_MOUSE Dual specificity protein phosphatase 4 31 4.0
sp|Q13115|DUS4_HUMAN Dual specificity protein phosphatase 4... 31 4.0
sp|Q62767|DUS4_RAT Dual specificity protein phosphatase 4 (... 31 4.0
sp|Q57640|Y181_METJA Hypothetical protein MJ0181 31 5.2
sp|O18805|DAXX_CERAE Death domain-associated protein 6 (Daxx) 31 5.2
sp|Q23255|MRE11_CAEEL Double-strand break repair protein mr... 30 8.9
>sp|Q8V439|R1AB_CVBLU Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes:
Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: p28;
p65; p210 (Papain-like proteinases 1/2)
(PL1-PRO/PL2-PRO); Peptide HD2 (p44); 3C-like proteinase
(3CL-PRO) (3CLp) (M-PRO) (p27); Unknown protein 1; p10;
p22; p12; Growth factor-like peptide (GFL) (p15);
RNA-directed RNA polymerase (RdRp) (Pol) (p100); Helicase
(Hel) (p67); Unknown protein 2; p35; Unknown protein 3]
Length = 7094
Score = 33.1 bits (74), Expect = 1.1
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Frame = +1
Query: 385 NFQTNYKSILSSYYVDCVKIIDEIKDCNEKVDYLVNFLQLL---SIYYTQTL----YRDI 543
N + +KS+L++YY+D VK K++Y + Q YYTQ + ++
Sbjct: 1864 NLKQTFKSVLTTYYLDDVK----------KIEYKPDLSQYYCDGGKYYTQRIIKAQFKTF 1913
Query: 544 LAVSXXXXXXKKI-FLICDNRNAAIIYESLK--ITYKLTD 654
V K I ICD NA + ++S K + YK+T+
Sbjct: 1914 EKVDGVYTNFKLIGHTICDILNAKLGFDSSKEFVEYKVTE 1953
>sp|Q91A29|R1AB_CVBEN Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes:
Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: p28;
p65; p210 (Papain-like proteinases 1/2)
(PL1-PRO/PL2-PRO); Peptide HD2 (p44); 3C-like proteinase
(3CL-PRO) (3CLp) (M-PRO) (p27); Unknown protein 1; p10;
p22; p12; Growth factor-like peptide (GFL) (p15);
RNA-directed RNA polymerase (RdRp) (Pol) (p100); Helicase
(Hel) (p67); Unknown protein 2; p35; Unknown protein 3]
Length = 7094
Score = 32.7 bits (73), Expect = 1.4
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 7/97 (7%)
Frame = +1
Query: 385 NFQTNYKSILSSYYVDCVKIIDEIKDCNEKVDYLVNFLQLLSIYYTQTL----YRDILAV 552
N + +KS+L++YY+D VK I+ D ++ Y + YYTQ + ++ V
Sbjct: 1864 NLKQTFKSVLTTYYLDDVKKIEYNPDLSQ---YYCDG----GKYYTQRIIKAQFKTFEKV 1916
Query: 553 SXXXXXXKKI-FLICDNRNAAIIYESLK--ITYKLTD 654
K I ICD NA + ++S K + YK+T+
Sbjct: 1917 DGVYTNFKLIGHTICDILNAKLGFDSSKEFVEYKVTE 1953
>sp|Q66198|R1AB_CVBM Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes:
Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: p28;
p65; p210 (Papain-like proteinases 1/2)
(PL1-PRO/PL2-PRO); Peptide HD2 (p44); 3C-like proteinase
(3CL-PRO) (3CLp) (M-PRO) (p27); Unknown protein 1; p10;
p22; p12; Growth factor-like peptide (GFL) (p15);
RNA-directed RNA polymerase (RdRp) (Pol) (p100); Helicase
(Hel) (p67); Unknown protein 2; p35; Unknown protein 3]
Length = 7094
Score = 32.7 bits (73), Expect = 1.4
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Frame = +1
Query: 385 NFQTNYKSILSSYYVDCVKIIDEIKDCNEKVDYLVNFLQLL---SIYYTQTL----YRDI 543
N + +KS+L++YY+D VK K++Y + Q YYTQ + ++
Sbjct: 1864 NLKQTFKSVLTTYYLDDVK----------KIEYKPDLSQYYCDGGKYYTQRIIKAQFKTF 1913
Query: 544 LAVSXXXXXXKKI-FLICDNRNAAIIYESLK--ITYKLTD 654
V K I +CD NA + ++S K + YK+T+
Sbjct: 1914 EKVDGVYTNFKLIGHTVCDILNAKLGFDSSKEFVEYKVTE 1953
>sp|Q8V6W7|R1AB_CVBQ Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes:
Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: p28;
p65; p210 (Papain-like proteinases 1/2)
(PL1-PRO/PL2-PRO); Peptide HD2 (p44); 3C-like proteinase
(3CL-PRO) (3CLp) (M-PRO) (p27); Unknown protein 1; p10;
p22; p12; Growth factor-like peptide (GFL) (p15);
RNA-directed RNA polymerase (RdRp) (Pol) (p100); Helicase
(Hel) (p67); Unknown protein 2; p35; Unknown protein 3]
Length = 7059
Score = 32.7 bits (73), Expect = 1.4
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Frame = +1
Query: 385 NFQTNYKSILSSYYVDCVKIIDEIKDCNEKVDYLVNFLQLL---SIYYTQTL----YRDI 543
N + +KS+L++YY+D VK K++Y + Q YYTQ + ++
Sbjct: 1864 NLKQTFKSVLTTYYLDDVK----------KIEYKPDLSQYYCDGGKYYTQRIIKAQFKTF 1913
Query: 544 LAVSXXXXXXKKI-FLICDNRNAAIIYESLK--ITYKLTD 654
V K I +CD NA + ++S K + YK+T+
Sbjct: 1914 EKVDGVYTNFKLIGHTVCDILNAKLGFDSSKEFVEYKVTE 1953
>sp|Q8BFV3|DUS4_MOUSE Dual specificity protein phosphatase 4
Length = 398
Score = 31.2 bits (69), Expect = 4.0
Identities = 10/29 (34%), Positives = 22/29 (75%)
Frame = +1
Query: 391 QTNYKSILSSYYVDCVKIIDEIKDCNEKV 477
+ N+K+ +SS++++ ++ ID +KDC +V
Sbjct: 252 EDNHKADISSWFMEAIEYIDAVKDCRGRV 280
>sp|Q13115|DUS4_HUMAN Dual specificity protein phosphatase 4 (Mitogen-activated protein
kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2)
(Dual specificity protein phosphatase hVH2)
Length = 394
Score = 31.2 bits (69), Expect = 4.0
Identities = 10/29 (34%), Positives = 22/29 (75%)
Frame = +1
Query: 391 QTNYKSILSSYYVDCVKIIDEIKDCNEKV 477
+ N+K+ +SS++++ ++ ID +KDC +V
Sbjct: 248 EDNHKADISSWFMEAIEYIDAVKDCRGRV 276
>sp|Q62767|DUS4_RAT Dual specificity protein phosphatase 4 (Mitogen-activated protein
kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2)
Length = 395
Score = 31.2 bits (69), Expect = 4.0
Identities = 10/29 (34%), Positives = 22/29 (75%)
Frame = +1
Query: 391 QTNYKSILSSYYVDCVKIIDEIKDCNEKV 477
+ N+K+ +SS++++ ++ ID +KDC +V
Sbjct: 249 EDNHKADISSWFMEAIEYIDAVKDCRGRV 277
>sp|Q57640|Y181_METJA Hypothetical protein MJ0181
Length = 246
Score = 30.8 bits (68), Expect = 5.2
Identities = 40/149 (26%), Positives = 67/149 (44%), Gaps = 19/149 (12%)
Frame = +1
Query: 148 EKSIEAQIKDLITLLIFTDSPTLKKIYEIMAFV--SKNKEMDSFLSQMFSVVMPLSENEK 321
+ I +++ + FT+ LKK+ A + KN ++D+ ++ ++ + E+
Sbjct: 29 DDKIAEKLERFFKAINFTNPRHLKKVLNKYAILIEFKNSKIDN--ERLIPEIIRIENGER 86
Query: 322 KRSG---DVIAILYFRI----------EDPELKLNFQTNYKSILSSY---YVDCVKIIDE 453
KR G D + +LYF I E K QTN + L SY Y +I+
Sbjct: 87 KRKGYLFDTVFVLYFIILYEFYYGKYLEVKRYKCRLQTN--TGLQSYFERYSLLSQIMKV 144
Query: 454 IKDCN-EKVDYLVNFLQLLSIYYTQTLYR 537
IK+ N +D ++ L LL Y+Q YR
Sbjct: 145 IKNRNANDMDRVITNLMLL---YSQLGYR 170
>sp|O18805|DAXX_CERAE Death domain-associated protein 6 (Daxx)
Length = 736
Score = 30.8 bits (68), Expect = 5.2
Identities = 14/32 (43%), Positives = 19/32 (59%)
Frame = -3
Query: 115 LMCHQIY*ALDCKVQIQEHLDLIYYYYCSLTN 20
LM + + ++Q Q HLDLIY + C LTN
Sbjct: 311 LMAQDAFRNVGIRLQEQRHLDLIYNFGCHLTN 342
>sp|Q23255|MRE11_CAEEL Double-strand break repair protein mre-11
Length = 728
Score = 30.0 bits (66), Expect = 8.9
Identities = 16/44 (36%), Positives = 24/44 (54%)
Frame = +1
Query: 73 VPCNQVPNKSGDTLTNECCAIDENAEKSIEAQIKDLITLLIFTD 204
VPC+Q P+ + DT+ + DE A E D+I +L+ TD
Sbjct: 34 VPCSQRPDAANDTMVEDLDEGDEPAHDESE----DIIKILVATD 73
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,792,339
Number of Sequences: 369166
Number of extensions: 1611599
Number of successful extensions: 4156
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4022
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4154
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8790245790
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)