Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_I01
(562 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q13568|IRF5_HUMAN Interferon regulatory factor 5 (IRF-5) 56 7e-08
sp|P56477|IRF5_MOUSE Interferon regulatory factor 5 (IRF-5) 54 3e-07
sp|P97431|IRF6_MOUSE Interferon regulatory factor 6 (IRF-6) 49 1e-05
sp|O14896|IRF6_HUMAN Interferon regulatory factor 6 (IRF-6) 48 2e-05
sp|P70434|IRF7_MOUSE Interferon regulatory factor 7 (IRF-7) 45 1e-04
sp|Q15306|IRF4_HUMAN Interferon regulatory factor 4 (IRF-4)... 43 5e-04
sp|Q02556|IRF8_HUMAN Interferon regulatory factor 8 (IRF-8)... 42 0.001
sp|Q64287|IRF4_MOUSE Interferon regulatory factor 4 (IRF-4)... 42 0.001
sp|P23611|IRF8_MOUSE Interferon regulatory factor 8 (IRF-8)... 40 0.003
sp|Q90871|IRF8_CHICK Interferon regulatory factor 8 (IRF-8)... 40 0.005
>sp|Q13568|IRF5_HUMAN Interferon regulatory factor 5 (IRF-5)
Length = 498
Score = 55.8 bits (133), Expect = 7e-08
Identities = 38/143 (26%), Positives = 61/143 (42%), Gaps = 5/143 (3%)
Frame = +2
Query: 17 ENLSTAGPEPIE----PQIYQYVSDSNKYCVDMLLENMQRGGVLTILNGSIYAEKLCKCA 184
E + GP +E P SD ++ + LL+ + RG +L + +YA +LC+C
Sbjct: 284 EQVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCK 343
Query: 185 TFVYRPGNNGEFYFVDKLNRRDKMMIFDFRSFLEELHYFQRGLGN-KPHVELILAFGQQI 361
F P + + + R K +F FL EL FQ+G N P E+ FG++
Sbjct: 344 VFWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEW 403
Query: 362 KDNSSPESLYVWCRLASCKAWFL 430
D E + ++ A L
Sbjct: 404 PDRKpreKKLITVQVVPVAARLL 426
>sp|P56477|IRF5_MOUSE Interferon regulatory factor 5 (IRF-5)
Length = 497
Score = 53.9 bits (128), Expect = 3e-07
Identities = 35/122 (28%), Positives = 54/122 (44%), Gaps = 5/122 (4%)
Frame = +2
Query: 17 ENLSTAGPEPIE----PQIYQYVSDSNKYCVDMLLENMQRGGVLTILNGSIYAEKLCKCA 184
E + GP +E P SD ++ + LL+ + RG +L + +YA +LC+C
Sbjct: 283 EQVELFGPVTLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCK 342
Query: 185 TFVYRPGNNGEFYFVDKLNRRDKMMIFDFRSFLEELHYFQRGLGN-KPHVELILAFGQQI 361
F P + + R K +F FL EL FQ+G N P E+ FG++
Sbjct: 343 VFWSGPCALAHGSCPNPIQREVKTKLFSLEQFLNELILFQKGQTNTPPPFEIFFCFGEEW 402
Query: 362 KD 367
D
Sbjct: 403 PD 404
>sp|P97431|IRF6_MOUSE Interferon regulatory factor 6 (IRF-6)
Length = 467
Score = 48.5 bits (114), Expect = 1e-05
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 2/124 (1%)
Frame = +2
Query: 17 ENLSTAGPEPIEPQIYQYVSDSNKYCVDMLLENMQRGGVLTILNGSIYAEKLCKCATFVY 196
E + GPE I ++ K LL+ M RG +L + +IYA +LC+C VY
Sbjct: 272 EQVKFPGPEHI-------TNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCK--VY 322
Query: 197 RPGNNGEFYFVDKL-NRRDKMMIFDFRSFLEELHYFQRG-LGNKPHVELILAFGQQIKDN 370
G L R+ K+ +F +FL EL Q+G + +P E+ L FG++ D
Sbjct: 323 WSGPCAPSLAAPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYLCFGEEWPDG 382
Query: 371 SSPE 382
E
Sbjct: 383 KPLE 386
>sp|O14896|IRF6_HUMAN Interferon regulatory factor 6 (IRF-6)
Length = 467
Score = 47.8 bits (112), Expect = 2e-05
Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 2/124 (1%)
Frame = +2
Query: 17 ENLSTAGPEPIEPQIYQYVSDSNKYCVDMLLENMQRGGVLTILNGSIYAEKLCKCATFVY 196
E + GPE I ++ K LL+ M RG +L + +IYA +LC+C VY
Sbjct: 272 EQVKFPGPEHI-------TNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCK--VY 322
Query: 197 RPGNNGEFYFVDKL-NRRDKMMIFDFRSFLEELHYFQRG-LGNKPHVELILAFGQQIKDN 370
G L R+ K+ +F +FL +L Q+G + +P E+ L FG++ D
Sbjct: 323 WSGPCAPSLVAPNLIERQKKVKLFCLETFLSDLIAHQKGQIEKQPPFEIYLCFGEEWPDG 382
Query: 371 SSPE 382
E
Sbjct: 383 KPLE 386
>sp|P70434|IRF7_MOUSE Interferon regulatory factor 7 (IRF-7)
Length = 457
Score = 45.1 bits (105), Expect = 1e-04
Identities = 39/139 (28%), Positives = 60/139 (43%), Gaps = 7/139 (5%)
Frame = +2
Query: 29 TAGPEP-IEPQIYQYVSDSNKYCVDMLLENMQRGGVLTILNGSIYAEKLCKCATF--VYR 199
T+ P+P I P + + + LL+++ G L + S++A ++ KC + V
Sbjct: 277 TSEPQPVIFPSPAELPDQKQLHYTETLLQHVSPGLQLELRGPSLWALRMGKCKVYWEVGS 336
Query: 200 P-GNNGEFYFVDKLNRRDKMMIFDFRSFLEELHYFQ-RGLGNKPHVELILAFGQQIKDNS 373
P G G L R IFDF +F EL F+ R PH + L FGQ +
Sbjct: 337 PMGTTGPSTPPQLLERNRHTPIFDFSTFFRELEEFRARRRQGSPHYTIYLGFGQDLSAGR 396
Query: 374 SPESLYVWCRLAS--CKAW 424
E + +L CKA+
Sbjct: 397 PKEKTLILVKLEPWVCKAY 415
>sp|Q15306|IRF4_HUMAN Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific
interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple
myeloma oncogene 1)
Length = 451
Score = 43.1 bits (100), Expect = 5e-04
Identities = 29/111 (26%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = +2
Query: 47 IEPQIYQYVSDSN-KYCVDMLLENMQRGGVLTILNGSIYAEKLCKCATFVYRP---GNNG 214
++ ++ Y D+ + ++ LL +++RG VL + +YA++LC+ + P N+
Sbjct: 287 LDQVLFPYPEDNGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDR 346
Query: 215 EFYFVDKLNRRDKMMIFDFRSFLEELHYFQRGLGNKPHVELILAFGQQIKD 367
+KL R +FD + FL EL F + P ++ L FG++ D
Sbjct: 347 P----NKLERDQTCKLFDTQQFLSELQAFAHHGRSLPRFQVTLCFGEEFPD 393
>sp|Q02556|IRF8_HUMAN Interferon regulatory factor 8 (IRF-8) (Interferon consensus
sequence binding protein) (ICSBP)
Length = 426
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 8/119 (6%)
Frame = +2
Query: 35 GPEPIE----PQIYQYVSDSNKYCVDMLLENMQRGGVLTILNGSIYAEKLCKCATFVYRP 202
GPE +E P S+ + L +++RG +L ++ ++LC+ F
Sbjct: 243 GPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFC--S 300
Query: 203 GN----NGEFYFVDKLNRRDKMMIFDFRSFLEELHYFQRGLGNKPHVELILAFGQQIKD 367
GN G +KL R + + +FD F EL F G P ++L FG++ D
Sbjct: 301 GNAVVCKGR---PNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPD 356
>sp|Q64287|IRF4_MOUSE Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific
interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1
interaction partner) (Transcriptional activator PIP)
Length = 450
Score = 41.6 bits (96), Expect = 0.001
Identities = 28/112 (25%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Frame = +2
Query: 47 IEPQIYQYVSDSN-KYCVDMLLENMQRGGVLTILNGSIYAEKLCKCATFVYRPGNNGEFY 223
++ ++ Y D+ + ++ LL +++RG VL + +YA++LC+ + +G
Sbjct: 287 LDQVLFPYPDDNGQRKNIEKLLSHLERGLVLWMAPDGLYAKRLCQSRIYW-----DGPLA 341
Query: 224 FV----DKLNRRDKMMIFDFRSFLEELHYFQRGLGNKPHVELILAFGQQIKD 367
+KL R +FD + FL EL F P ++ L FG++ D
Sbjct: 342 LCSDRPNKLERDQTCKLFDTQQFLSELQVFAHHGRPAPRFQVTLCFGEEFPD 393
>sp|P23611|IRF8_MOUSE Interferon regulatory factor 8 (IRF-8) (Interferon consensus
sequence binding protein) (ICSBP)
Length = 424
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 8/119 (6%)
Frame = +2
Query: 35 GPEPIEPQIYQYV----SDSNKYCVDMLLENMQRGGVLTILNGSIYAEKLCKCATFVYRP 202
GP+ +EP + S+ + L +++RG +L ++ ++LC+ F
Sbjct: 241 GPDGLEPVCFPTADTIPSERQRQVTRKLFGHLERGVLLHSNRKGVFVKRLCQGRVFC--S 298
Query: 203 GN----NGEFYFVDKLNRRDKMMIFDFRSFLEELHYFQRGLGNKPHVELILAFGQQIKD 367
GN G +KL R + + +FD F+ EL F P ++L FG++ D
Sbjct: 299 GNAVVCKGR---PNKLERDEVVQVFDTNQFIRELQQFYATQSRLPDSRVVLCFGEEFPD 354
>sp|Q90871|IRF8_CHICK Interferon regulatory factor 8 (IRF-8) (Interferon consensus
sequence binding protein) (ICSBP)
Length = 425
Score = 39.7 bits (91), Expect = 0.005
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 1/99 (1%)
Frame = +2
Query: 74 SDSNKYCVDMLLENMQRGGVLTILNGSIYAEKLCKCATFVYRPGNNGEFYF-VDKLNRRD 250
+D K L +++RG +L I+ ++LC+ V+ GN + KL+R +
Sbjct: 262 NDRQKQITKKLFGHLERGVLLHSNKQGIFIKRLCQGR--VFWSGNTVVYKDRPSKLDRDE 319
Query: 251 KMMIFDFRSFLEELHYFQRGLGNKPHVELILAFGQQIKD 367
+ IFD F EL + G P ++L FG++ D
Sbjct: 320 VVKIFDTNLFFRELQQYYNNQGRFPDSRVMLCFGEEFPD 358
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,852,392
Number of Sequences: 369166
Number of extensions: 1294408
Number of successful extensions: 3154
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3091
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3149
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4029688280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)