Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_028_H18 (397 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P51826|AFF3_HUMAN AF4/FMR2 family member 3 (LAF-4 protei... 31 0.78 sp|P29148|Npre_PAEPO Bacillolysin precursor (Neutral protease) 31 1.0 sp|P87159|NIF1_SCHPO Mitosis inhibitor nif1 (Nim1 interacti... 29 3.0 sp|Q9NZW4|DSPP_HUMAN Dentin sialophosphoprotein precursor [... 29 3.9 sp|Q9Y5Y6|ST14_HUMAN Suppressor of tumorigenicity 14 (Matri... 29 3.9 sp|Q10024|DGKM_CAEEL Putative diacylglycerol kinase K06A1.6... 28 6.6 sp|P57137|FTSY_BUCAI Cell division protein ftsY homolog 28 6.6 sp|O35274|NEB2_RAT Neurabin-2 (Neurabin-II) (Neural tissue-... 28 8.6 sp|P42568|AF9_HUMAN Protein AF-9 (ALL1 fused gene from chro... 28 8.6 sp|Q12468|CSN5_YEAST COP9 signalosome complex subunit 5 28 8.6
>sp|P51826|AFF3_HUMAN AF4/FMR2 family member 3 (LAF-4 protein) (Lymphoid nuclear protein related to AF4) Length = 1227 Score = 31.2 bits (69), Expect = 0.78 Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 10/104 (9%) Frame = +2 Query: 77 KDMKKTTCDLLNDDDSSAIKPRAYRSAFSFRLKRSKCDTKINTHCHSKSDELGVANSQ-- 250 K +K CD N+DD IK S RL S +T HC+ + + + ++ Sbjct: 816 KSKRKRKCD--NEDDYREIKKSQGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNE 873 Query: 251 -----PLSPGANTAPVSATSHKKRGS---NILHIFTSNRNKTKP 358 P+SP ++ + TS S N +FTS + KP Sbjct: 874 KMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKP 917
>sp|P29148|Npre_PAEPO Bacillolysin precursor (Neutral protease) Length = 590 Score = 30.8 bits (68), Expect = 1.0 Identities = 29/121 (23%), Positives = 51/121 (42%) Frame = +2 Query: 5 SRINCLNTSDSELNKSPDSMSVNAKDMKKTTCDLLNDDDSSAIKPRAYRSAFSFRLKRSK 184 +RI L TSD ++K + S +KD T + N+D + ++ + S Sbjct: 158 ARIEALPTSDDTISKDAEEPSSVSKD---TYAEAANNDKTLSVD----KDELSLDKASVL 210 Query: 185 CDTKINTHCHSKSDELGVANSQPLSPGANTAPVSATSHKKRGSNILHIFTSNRNKTKPHQ 364 D+KI KS +AN QP P + + +G ++L ++ + N +P Sbjct: 211 KDSKIEAVEAEKSSIAKIANLQP-----EVDPKAELYYYPKGDDLLLVYVTEVNVLEPAP 265 Query: 365 L 367 L Sbjct: 266 L 266
>sp|P87159|NIF1_SCHPO Mitosis inhibitor nif1 (Nim1 interacting factor 1) Length = 681 Score = 29.3 bits (64), Expect = 3.0 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Frame = +2 Query: 20 LNTSDSELNKSPDSMSVNAKDMKKTTCDLLNDDDSSAIKPRAYRSAFSFRLKRSKCDTKI 199 LNT+ + LNK + A+ K++ L+ D+ A+K R + R SK + + Sbjct: 15 LNTTTALLNKKDGNDDDKAEHSKRSGYHGLSPLDALALKHRDLNRKLNLRAMMSKSEDNL 74 Query: 200 ----NTHCHSKSDELGVANSQPLSPGANTAP 280 T S SD L + P SP ++P Sbjct: 75 QILKETTSGSSSDLLNI--ESPASPAEASSP 103
>sp|Q9NZW4|DSPP_HUMAN Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)] Length = 1253 Score = 28.9 bits (63), Expect = 3.9 Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 1/102 (0%) Frame = +2 Query: 14 NCLNTSDS-ELNKSPDSMSVNAKDMKKTTCDLLNDDDSSAIKPRAYRSAFSFRLKRSKCD 190 N ++SDS + + S DS S N D ++ D + DSS + S S + S Sbjct: 837 NSSDSSDSSDSSDSSDSDSSNRSDSSNSS-DSSDSSDSSNSSDSSDSSDSSDSNESSNSS 895 Query: 191 TKINTHCHSKSDELGVANSQPLSPGANTAPVSATSHKKRGSN 316 ++ S SD +NS S +N++ S +S+ SN Sbjct: 896 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 937
>sp|Q9Y5Y6|ST14_HUMAN Suppressor of tumorigenicity 14 (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor associated differentially-expressed gene-15 protein) Length = 855 Score = 28.9 bits (63), Expect = 3.9 Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 5/114 (4%) Frame = +2 Query: 14 NCLNTSDSELNKSPDS---MSVNAKDMKKT--TCDLLNDDDSSAIKPRAYRSAFSFRLKR 178 +C + SD ELN S D+ + K K CD +ND ++ + A +FR Sbjct: 476 DCTDHSD-ELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRCSN 534 Query: 179 SKCDTKINTHCHSKSDELGVANSQPLSPGANTAPVSATSHKKRGSNILHIFTSN 340 KC +K + C+ K D+ G + + P N V+ T H R N L + N Sbjct: 535 GKCLSK-SQQCNGK-DDCGDGSDEASCPKVNV--VTCTKHTYRCLNGLCLSKGN 584
>sp|Q10024|DGKM_CAEEL Putative diacylglycerol kinase K06A1.6 (Diglyceride kinase) (DGK) (DAG kinase) Length = 937 Score = 28.1 bits (61), Expect = 6.6 Identities = 14/65 (21%), Positives = 30/65 (46%) Frame = +2 Query: 104 LLNDDDSSAIKPRAYRSAFSFRLKRSKCDTKINTHCHSKSDELGVANSQPLSPGANTAPV 283 + +D+ S + L R + D + NT C+ + ++ G+ ++ PL+ N + Sbjct: 520 VFSDEPISQLMQAILHETIVTHLDRWRIDVEPNTSCNLEEEDDGMQSALPLTVMTNYFSI 579 Query: 284 SATSH 298 A +H Sbjct: 580 GADAH 584
>sp|P57137|FTSY_BUCAI Cell division protein ftsY homolog Length = 378 Score = 28.1 bits (61), Expect = 6.6 Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 13/79 (16%) Frame = +2 Query: 5 SRINCLNTSDSELNKSPDSMSVNAKDM-------------KKTTCDLLNDDDSSAIKPRA 145 S+I T D N + + +N +D+ KK D LND K + Sbjct: 15 SKIKKKKTIDIRQNNTDKNHDINHEDLYTKKDLLIKQDNPKKDEIDTLNDHGKDIEKAQN 74 Query: 146 YRSAFSFRLKRSKCDTKIN 202 ++ F RLK+S TK N Sbjct: 75 TKNNFFLRLKKSLKTTKKN 93
>sp|O35274|NEB2_RAT Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin binding protein II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130) (PP1bp134) Length = 817 Score = 27.7 bits (60), Expect = 8.6 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Frame = +2 Query: 212 HSKSDELGV-ANSQPLSPGANTAPVSATSHKKRGSNILHI 328 H + E G+ A P +PG + AP A HKK GSN+ I Sbjct: 19 HRSAYEAGIQALKPPDAPGPDEAP-KAAHHKKYGSNVHRI 57
>sp|P42568|AF9_HUMAN Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) Length = 568 Score = 27.7 bits (60), Expect = 8.6 Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 1/72 (1%) Frame = +2 Query: 164 FRLKRSKCDTKINTHCH-SKSDELGVANSQPLSPGANTAPVSATSHKKRGSNILHIFTSN 340 FR K K N H S S ++S S ++++ S++S S+ +S+ Sbjct: 131 FRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 190 Query: 341 RNKTKPHQLLKQ 376 + +KPH+L+K+ Sbjct: 191 TSFSKPHKLMKE 202
>sp|Q12468|CSN5_YEAST COP9 signalosome complex subunit 5 Length = 455 Score = 27.7 bits (60), Expect = 8.6 Identities = 14/45 (31%), Positives = 22/45 (48%) Frame = +2 Query: 95 TCDLLNDDDSSAIKPRAYRSAFSFRLKRSKCDTKINTHCHSKSDE 229 T + +DD+S+ F L R+ +TK+N HC + DE Sbjct: 229 TIESKSDDNSATSYYELETIIFDSELNRALFETKLNLHCVIEDDE 273
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 42,602,073 Number of Sequences: 369166 Number of extensions: 744213 Number of successful extensions: 1638 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1601 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1635 length of database: 68,354,980 effective HSP length: 97 effective length of database: 50,435,685 effective search space used: 1714813290 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)