Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_028_G05 (246 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q91VE3|KLK7_MOUSE Kallikrein-7 precursor (Stratum corneu... 64 8e-11 sp|Q9UKR3|KLK13_HUMAN Kallikrein 13 precursor (Kallikrein-l... 63 2e-10 sp|Q61754|KLK24_MOUSE Glandular kallikrein K24 precursor (T... 63 2e-10 sp|P15950|KLK3_RAT Glandular kallikrein 3, submandibular (T... 62 3e-10 sp|P15948|KLK22_MOUSE Glandular kallikrein K22 precursor (T... 61 7e-10 sp|P15946|KLK11_MOUSE Glandular kallikrein K11 precursor (T... 61 9e-10 sp|P36374|KLK8_RAT Prostatic glandular kallikrein-8 precurs... 60 2e-09 sp|Q92876|KLK6_HUMAN Kallikrein 6 precursor (Protease M) (N... 60 2e-09 sp|P15947|KLK6_MOUSE Glandular kallikrein K6 precursor (Tis... 60 2e-09 sp|Q8VHK8|TM11D_MOUSE Transmembrane protease, serine 11D pr... 60 2e-09
>sp|Q91VE3|KLK7_MOUSE Kallikrein-7 precursor (Stratum corneum chymotryptic enzyme) (Thymopsin) Length = 249 Score = 64.3 bits (155), Expect = 8e-11 Identities = 30/60 (50%), Positives = 38/60 (63%) Frame = +2 Query: 2 AGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWI 181 AG T++C GDSGGPL C D + G+VS+GT PCGQPN P VYT+V + W+ Sbjct: 187 AGIPDSKTNTCNGDSGGPLVCNDTLQ-----GLVSWGTYPCGQPNDPGVYTQVCKYKRWV 241
>sp|Q9UKR3|KLK13_HUMAN Kallikrein 13 precursor (Kallikrein-like protein 4) (KLK-L4) Length = 277 Score = 63.2 bits (152), Expect = 2e-10 Identities = 32/61 (52%), Positives = 36/61 (59%) Frame = +2 Query: 2 AGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWI 181 AG+ SC GDSGGPL C + GIVS+G PCGQP+ P VYTRVS WI Sbjct: 204 AGTKEGGKDSCEGDSGGPLVC-----NRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWI 258 Query: 182 R 184 R Sbjct: 259 R 259
>sp|Q61754|KLK24_MOUSE Glandular kallikrein K24 precursor (Tissue kallikrein 24) (mGK-24) Length = 263 Score = 62.8 bits (151), Expect = 2e-10 Identities = 28/52 (53%), Positives = 37/52 (71%) Frame = +2 Query: 29 SCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWIR 184 +C GDSGGPL C DG H GI S+G VPCG+PN P++YT++ + A WI+ Sbjct: 210 TCAGDSGGPLIC-DGILH----GITSWGPVPCGKPNAPAIYTKLIKFASWIK 256
>sp|P15950|KLK3_RAT Glandular kallikrein 3, submandibular (Tissue kallikrein) (S1 kallikrein) (RGK-3) (RSGK-50) Length = 188 Score = 62.4 bits (150), Expect = 3e-10 Identities = 29/61 (47%), Positives = 39/61 (63%) Frame = +2 Query: 2 AGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWI 181 AG +CRGDSGGPL C DG + GI S+G+VPCG+PN P +YT++ + WI Sbjct: 126 AGELEGGKDTCRGDSGGPLIC-DG----VLQGITSWGSVPCGEPNKPGIYTKLIKFTSWI 180 Query: 182 R 184 + Sbjct: 181 K 181
>sp|P15948|KLK22_MOUSE Glandular kallikrein K22 precursor (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase) Length = 259 Score = 61.2 bits (147), Expect = 7e-10 Identities = 27/61 (44%), Positives = 39/61 (63%) Frame = +2 Query: 2 AGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWI 181 AG +C+GDSGGPL C DG + GI S+G+ PCG+PN P++YT++ + WI Sbjct: 197 AGEMNGGKDTCKGDSGGPLIC-DG----VLQGITSWGSTPCGEPNAPAIYTKLIKFTSWI 251 Query: 182 R 184 + Sbjct: 252 K 252
>sp|P15946|KLK11_MOUSE Glandular kallikrein K11 precursor (Tissue kallikrein 11) (mGK-11) Length = 261 Score = 60.8 bits (146), Expect = 9e-10 Identities = 26/52 (50%), Positives = 36/52 (69%) Frame = +2 Query: 29 SCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWIR 184 +C+GDSGGPL C DG H GI ++G +PCG+PN P VYT++ + WI+ Sbjct: 208 TCKGDSGGPLIC-DGVLH----GITAWGPIPCGKPNTPGVYTKLIKFTNWIK 254
>sp|P36374|KLK8_RAT Prostatic glandular kallikrein-8 precursor (Tissue kallikrein) (P1 kallikrein) (RGK-8) Length = 261 Score = 60.1 bits (144), Expect = 2e-09 Identities = 26/51 (50%), Positives = 37/51 (72%) Frame = +2 Query: 32 CRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWIR 184 C+GDSGGPL C DG + GI S+G++PCG+PN PSVYT++ + W++ Sbjct: 209 CKGDSGGPLIC-DG----VLQGITSWGSMPCGEPNKPSVYTKLIKFTSWMK 254
>sp|Q92876|KLK6_HUMAN Kallikrein 6 precursor (Protease M) (Neurosin) (Zyme) (SP59) Length = 244 Score = 60.1 bits (144), Expect = 2e-09 Identities = 28/61 (45%), Positives = 36/61 (59%) Frame = +2 Query: 2 AGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWI 181 AG + SC+GDSGGPL C D H++ G+VS+G +PCG P VYT V WI Sbjct: 183 AGDEKYGKDSCQGDSGGPLVCGD----HLR-GLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237 Query: 182 R 184 + Sbjct: 238 Q 238
>sp|P15947|KLK6_MOUSE Glandular kallikrein K6 precursor (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B) Length = 261 Score = 60.1 bits (144), Expect = 2e-09 Identities = 29/52 (55%), Positives = 34/52 (65%) Frame = +2 Query: 29 SCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWIR 184 +C GDSGGPL C DG + GI S+G PCG+PNVP +YTRV WIR Sbjct: 208 TCAGDSGGPLIC-DG----VLQGITSWGPSPCGKPNVPGIYTRVLNFNTWIR 254
>sp|Q8VHK8|TM11D_MOUSE Transmembrane protease, serine 11D precursor (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain] Length = 417 Score = 60.1 bits (144), Expect = 2e-09 Identities = 31/61 (50%), Positives = 37/61 (60%) Frame = +2 Query: 2 AGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWI 181 AG + +C+GDSGGPL D R+ VGIVS+G CG PN P VYTRV+ WI Sbjct: 353 AGMRSGAVDACQGDSGGPLVQEDSRRLWFVVGIVSWG-YQCGLPNKPGVYTRVTAYRNWI 411 Query: 182 R 184 R Sbjct: 412 R 412
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,567,205 Number of Sequences: 369166 Number of extensions: 543549 Number of successful extensions: 2208 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1804 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1837 length of database: 68,354,980 effective HSP length: 52 effective length of database: 58,748,760 effective search space used: 1703714040 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)