Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_E07
(840 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P98060|NAS35_CAEEL Zinc metalloproteinase nas-35 precurs... 113 7e-25
sp|Q9U3S9|NAS6_CAEEL Zinc metalloproteinase nas-6 precursor... 110 4e-24
sp|Q20958|NAS29_CAEEL Zinc metalloproteinase nas-29 precurs... 110 4e-24
sp|Q19269|NAS14_CAEEL Zinc metalloproteinase nas-14 precurs... 109 8e-24
sp|P55113|NAS7_CAEEL Zinc metalloproteinase nas-7 precursor... 109 1e-23
sp|Q7Z0M7|NAS23_CAEEL Zinc metalloproteinase nas-23 precurs... 108 1e-23
sp|P42674|BP10_PARLI Blastula protease 10 precursor 106 9e-23
sp|P98069|BMPH_STRPU Bone morphogenetic protein 1 homolog p... 105 2e-22
sp|Q9N2V2|NAS30_CAEEL Zinc metalloproteinase nas-30 precurs... 105 2e-22
sp|Q18439|NAS8_CAEEL Zinc metalloproteinase nas-8 precursor... 103 5e-22
>sp|P98060|NAS35_CAEEL Zinc metalloproteinase nas-35 precursor (Nematode astacin 35)
(Dumpy protein 31) (Tollish protein 2)
Length = 592
Score = 113 bits (282), Expect = 7e-25
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 2/208 (0%)
Frame = +1
Query: 223 AMDIYQNETCLKFRTAKLSDPYSVIIRKGSGGCNAILGQDRKTGTQTVNLGIGCRWYGLF 402
A++ + N TCL F+ ++ + I+ GC + +G+ Q V+L C G+
Sbjct: 161 ALEHWHNITCLNFQRNDQANSGNRIVFTDVDGCASNVGRHPLGEEQLVSLAPECIRLGVI 220
Query: 403 LHELGHTIGLHHEHQHPDRDTGVDVQWDNVDPTMKVWFNTIDKNDVNMFGVPYDMQSVMH 582
HE+ H +G HE PDRD V V+W+N+D K F D +DV+ GVPYD S+MH
Sbjct: 221 AHEVAHALGFWHEQSRPDRDQYVTVRWENIDKDSKGQFLKEDPDDVDNAGVPYDYGSIMH 280
Query: 583 YGQWAFSKTDENGNPLTTIVAKDPEFQRYLYYVWMKDLSFGDVKRINLMYKCNQHCPKNI 762
Y AFSK D+ L TI ++Q+ + LSF D++ +N +Y C+ CP +
Sbjct: 281 YRSKAFSKFDD----LYTISTYVTDYQKTIGQ--RDQLSFNDIRLMNKIY-CSAVCPSKL 333
Query: 763 PCSERDGFI-TKNC-KCETKQDFAKRRC 840
PC +R G+ + C +C F + C
Sbjct: 334 PC-QRGGYTDPRRCDRCRCPDGFTGQYC 360
>sp|Q9U3S9|NAS6_CAEEL Zinc metalloproteinase nas-6 precursor (Nematode astacin 6)
Length = 344
Score = 110 bits (276), Expect = 4e-24
Identities = 70/207 (33%), Positives = 106/207 (51%)
Frame = +1
Query: 118 FMAEADETKRWENATIVYQIVLTDFRKDEIDGLLNAMDIYQNETCLKFRTAKLSDPYSVI 297
F A ++ WE I Y++ T F +EI L A D Y+ TC++F + Y I
Sbjct: 71 FNALKNKQLTWEGGVIPYEMD-TAFSPNEIKILEKAFDSYRRTTCIRFEKREGQTDYLNI 129
Query: 298 IRKGSGGCNAILGQDRKTGTQTVNLGIGCRWYGLFLHELGHTIGLHHEHQHPDRDTGVDV 477
++ GC + +G R G Q ++LG GC ++ + +HEL H++G HEH DRD + +
Sbjct: 130 VK--GYGCYSQVG--RTGGKQEISLGRGCFFHEIIVHELMHSVGFWHEHSRADRDDHIKI 185
Query: 478 QWDNVDPTMKVWFNTIDKNDVNMFGVPYDMQSVMHYGQWAFSKTDENGNPLTTIVAKDPE 657
WDN+ P MK F+ I ++ G YD +S+MHY AFS+ N TI +
Sbjct: 186 NWDNILPGMKSQFDKISAVLQDLQGENYDYKSIMHYDSTAFSRNGRN-----TIETVENG 240
Query: 658 FQRYLYYVWMKDLSFGDVKRINLMYKC 738
F + + DLS D+ +IN +Y C
Sbjct: 241 FTQVIGTA--MDLSPLDIVKINKLYSC 265
>sp|Q20958|NAS29_CAEEL Zinc metalloproteinase nas-29 precursor (Nematode astacin 29)
Length = 532
Score = 110 bits (276), Expect = 4e-24
Identities = 72/233 (30%), Positives = 108/233 (46%), Gaps = 2/233 (0%)
Frame = +1
Query: 148 WENAT-IVYQIVLTDFRKDEIDGLLNAMDIYQNETCLKFRTAKLSDPYSVIIRKGSGGCN 324
W+N ++ LT K I L A+ + ETC++F Y + I G C
Sbjct: 147 WKNGVAFMFHESLTPIAKTAI---LKAVHFWYRETCIEFHPRTFQKEYLLFIGNDDG-CW 202
Query: 325 AILGQDRKTGTQTVNLGIGCRWYGLFLHELGHTIGLHHEHQHPDRDTGVDVQWDNVDPTM 504
+ +G+D G Q V++G GC +G+ HEL H +G+ HE DRD V V+ +
Sbjct: 203 STVGRDASQGKQVVSIGNGCEHFGVTSHELAHALGIFHEQSRFDRDESVVFNPRVVERDL 262
Query: 505 KVWFNTIDKNDVNMFGVPYDMQSVMHYGQWAFSKTDENGNPLTTIVAKDPEFQRYLYYVW 684
F I ++ +G+PYD+ SVMHY FS N + T+ A D Q+ +
Sbjct: 263 LFNFAKISPRQMSTYGLPYDIGSVMHYTPTEFS----NIPSIPTLAAIDTNLQQTMGQ-- 316
Query: 685 MKDLSFGDVKRINLMYKCNQHCPKNIPCSERDGFITKNCK-CETKQDFAKRRC 840
++ SF DV +N Y+C + CP PC ++NCK C+ F C
Sbjct: 317 LEGPSFVDVHIMNQHYQCQEKCPTQAPCQNGGFTNSRNCKVCKCPTGFGGAYC 369
>sp|Q19269|NAS14_CAEEL Zinc metalloproteinase nas-14 precursor (Nematode astacin 14)
Length = 503
Score = 109 bits (273), Expect = 8e-24
Identities = 73/208 (35%), Positives = 106/208 (50%), Gaps = 6/208 (2%)
Frame = +1
Query: 142 KRWENATIVYQIVLTDFRKDEIDGLLNAMDIYQNETCLKFRTAKLSDPYSVII--RKGSG 315
K W + Y + D+ + A D Y+ +TC++F K D + I R +
Sbjct: 123 KLWPEGQVPYMLE-EGMTNDQRTAIAQAFDEYKTKTCVRF-VPKTDDDFDYIYVKRNVAF 180
Query: 316 GCNAILGQDRKTGTQTVNLGIG-CRWYGLFLHELGHTIGLHHEHQHPDRDTGVDVQWDNV 492
GC++ +G R G QTV+L + C G+ HEL H +G HEH DRD VD+ DN+
Sbjct: 181 GCSSYVG--RAGGNQTVSLEVDKCFSKGIIAHELMHALGFFHEHSRTDRDDFVDINEDNI 238
Query: 493 DPTMKVWFNTIDKNDVNMFGVPYDMQSVMHYGQWAFSKTDENGNPLTTIVAKDPEF---Q 663
P M F + ++ G+PYD +SVMHY + AFS+ NG P TI+ KD E Q
Sbjct: 239 RPGMMRNFEKYPRKIIDSLGMPYDYESVMHYHKLAFSR---NGKP--TIIPKDNEADVGQ 293
Query: 664 RYLYYVWMKDLSFGDVKRINLMYKCNQH 747
RY LS D K++N +Y+C ++
Sbjct: 294 RY-------KLSEMDSKKVNKLYQCGEY 314
>sp|P55113|NAS7_CAEEL Zinc metalloproteinase nas-7 precursor (Nematode astacin 7)
Length = 382
Score = 109 bits (272), Expect = 1e-23
Identities = 66/199 (33%), Positives = 97/199 (48%)
Frame = +1
Query: 142 KRWENATIVYQIVLTDFRKDEIDGLLNAMDIYQNETCLKFRTAKLSDPYSVIIRKGSGGC 321
K W NA I Y I + E L A+ Y +TC++F + +P + I K G C
Sbjct: 87 KLWPNARIPYAIS-PHYSPHERALLAKAVKQYHEKTCIRFVPRQTGEPDYLFIGKVDG-C 144
Query: 322 NAILGQDRKTGTQTVNLGIGCRWYGLFLHELGHTIGLHHEHQHPDRDTGVDVQWDNVDPT 501
+ +G R +G Q ++L GC Y +HE+ H +G +HEH+ DRD +D+ W N+D
Sbjct: 145 FSEVG--RTSGVQVLSLDNGCMEYATIIHEMMHVVGFYHEHERWDRDNFIDIIWQNIDRG 202
Query: 502 MKVWFNTIDKNDVNMFGVPYDMQSVMHYGQWAFSKTDENGNPLTTIVAKDPEFQRYLYYV 681
F +D + + +G PYD +S++HY AFSK NG P K
Sbjct: 203 ALDQFGKVDLSKTSYYGQPYDYKSILHYDSLAFSK---NGFPTMLPKVKSATIGN----- 254
Query: 682 WMKDLSFGDVKRINLMYKC 738
+D S D+ +IN MY C
Sbjct: 255 -ARDFSDVDISKINRMYNC 272
>sp|Q7Z0M7|NAS23_CAEEL Zinc metalloproteinase nas-23 precursor (Nematode astacin 23)
Length = 537
Score = 108 bits (271), Expect = 1e-23
Identities = 64/197 (32%), Positives = 98/197 (49%)
Frame = +1
Query: 214 LLNAMDIYQNETCLKFRTAKLSDPYSVIIRKGSGGCNAILGQDRKTGTQTVNLGIGCRWY 393
L+ AM ++ TC+ F+ + S+ +++ GC + +G+D G Q +N+G GC +
Sbjct: 144 LVAAMAFWEKHTCVAFKK-RTSEKVYLLMSGQEEGCWSTVGRDEAQGAQILNIGTGCEMF 202
Query: 394 GLFLHELGHTIGLHHEHQHPDRDTGVDVQWDNVDPTMKVWFNTIDKNDVNMFGVPYDMQS 573
G+ HE+ H +GL HE DRD V + + T F + K ++ +G YD+ S
Sbjct: 203 GITSHEIAHALGLFHEQSRYDRDNYVQIVKSRIAQTNFYDFAVVGKKNMETYGQKYDIGS 262
Query: 574 VMHYGQWAFSKTDENGNPLTTIVAKDPEFQRYLYYVWMKDLSFGDVKRINLMYKCNQHCP 753
VMHY FS + GN +I+AKD Q + + SF DV +IN Y C ++C
Sbjct: 263 VMHYRPTEFSL--DGGN---SIIAKDVNMQNTMGQ--FRGPSFIDVAKINRHYNCEKNCK 315
Query: 754 KNIPCSERDGFITKNCK 804
I C KNCK
Sbjct: 316 NKITCLNGGYQHPKNCK 332
>sp|P42674|BP10_PARLI Blastula protease 10 precursor
Length = 597
Score = 106 bits (264), Expect = 9e-23
Identities = 75/233 (32%), Positives = 112/233 (48%), Gaps = 9/233 (3%)
Frame = +1
Query: 136 ETKRWENATIVYQIVLTDFRKDEIDGLLNAMDIYQNETCLKF--RTAKLS-----DPYSV 294
E++RW I Y V++ + + NAMD ++ TCL+F RT+ S + Y
Sbjct: 98 ESQRWPYKVIPY--VISPSSSGQSSLIRNAMDHWEQNTCLRFEPRTSSHSRQLGHNAYLS 155
Query: 295 IIRKGSGGCNAILGQDRKTGTQTVNLGIGCRWYGLFLHELGHTIGLHHEHQHPDRDTGVD 474
R GC + +G+ G Q +++G GC ++G +HE+GH IG HHE PDRD ++
Sbjct: 156 FFR--GSGCWSYVGK-AFNGEQQISIGNGCAYFGTIVHEIGHAIGFHHEQSRPDRDDYIN 212
Query: 475 VQWDNVDPTMKVWFNTIDKNDVNMFGVPYDMQSVMHYGQWAFSKTDENGNPLTTIVAKDP 654
V + N+ + F V V YD+ S+MHYG + FS NG P TI +DP
Sbjct: 213 VLYQNIQSGRQHNFAKYTWGRVTSRNVEYDVGSIMHYGGYGFS---SNGRP--TITTRDP 267
Query: 655 EFQRYLYYVWMKDLSFGDVKRINLMYKCN--QHCPKNIPCSERDGFITKNCKC 807
L LS D++ NL+Y+C+ + C C G+ C C
Sbjct: 268 RLNSRLGQ--RIALSPADIELANLIYECDDIEDCAGANECL-NGGYHDTECNC 317
>sp|P98069|BMPH_STRPU Bone morphogenetic protein 1 homolog precursor (SUBMP)
Length = 639
Score = 105 bits (262), Expect = 2e-22
Identities = 68/203 (33%), Positives = 103/203 (50%), Gaps = 4/203 (1%)
Frame = +1
Query: 142 KRWENATIVYQIVLTDFRKDEIDGLLNAMDIYQNETCLKF---RTAKLSDPYSVIIRKGS 312
+RW +A I Y+I +F + AM ++N TC+ F A ++ +
Sbjct: 108 RRWTDAVIPYEID-GNFTGSQRAMFKQAMRHWENYTCITFVERNPANSEHDNHIVFTYQA 166
Query: 313 GGCNAILGQDRKTGTQTVNLGIGCRWYGLFLHELGHTIGLHHEHQHPDRDTGVDVQWDNV 492
GC + +G+ + G Q V++G C +G+ +HELGH +G HEH PDR+ V + N+
Sbjct: 167 CGCCSFVGR-KGDGAQAVSVGKNCDKFGVVVHELGHVVGFWHEHTRPDRNEFVGIVHQNI 225
Query: 493 DPTMKVWFNTIDKNDVNMFGVPYDMQSVMHYGQWAFSKTDENGNPLTTIV-AKDPEFQRY 669
P + F +D +V+ G YD S+MHY + FS+ G L TI+ KDPE
Sbjct: 226 VPGQEYNFRVLDAAEVDSLGETYDFASIMHYARNTFSR----GIWLDTILPRKDPESGIR 281
Query: 670 LYYVWMKDLSFGDVKRINLMYKC 738
K LS GD+ + NL+YKC
Sbjct: 282 PEIGQRKHLSEGDIIQANLLYKC 304
>sp|Q9N2V2|NAS30_CAEEL Zinc metalloproteinase nas-30 precursor (Nematode astacin 30)
Length = 746
Score = 105 bits (261), Expect = 2e-22
Identities = 66/198 (33%), Positives = 101/198 (51%), Gaps = 4/198 (2%)
Frame = +1
Query: 226 MDIYQNETCLKFRTAKLSDPYSVIIRKGSGGCNAILGQDRKTGTQTVNLGIGCRWYGLFL 405
+ +++ ETC+++ Y + R GC + +G R G+Q +++G GC G+
Sbjct: 300 LGLWEKETCVRWSENGPGKDYVIFFR--GSGCYSSVG--RTGGSQLISIGYGCEDKGIVA 355
Query: 406 HELGHTIGLHHEHQHPDRDTGVDVQWDNVDPTMKVWFNTIDKNDVNMFGVPYDMQSVMHY 585
HE+GH++G HE PDRD + ++ D + F ++ GVPYD+ SVMHY
Sbjct: 356 HEVGHSLGFWHEQSRPDRDDYIHLRKDWIIKGTDGNFEKRSWEEIEDMGVPYDVGSVMHY 415
Query: 586 GQWAFSKTDENGNPLTTIVAKDPEFQRYLYYVWMKDLSFGDVKRINLMYKCNQHCPKNIP 765
G AF+K + TI KD +Q + + LSF DVK++N +Y CN CP +P
Sbjct: 416 GSNAFTKDWDQ----ITIETKDSRYQGTIGQ--RQKLSFIDVKQVNRLY-CNSVCPVALP 468
Query: 766 CSERDGFITKN----CKC 807
C G+ N CKC
Sbjct: 469 CM-HGGYPDPNNCAVCKC 485
>sp|Q18439|NAS8_CAEEL Zinc metalloproteinase nas-8 precursor (Nematode astacin 8)
Length = 403
Score = 103 bits (258), Expect = 5e-22
Identities = 65/201 (32%), Positives = 100/201 (49%)
Frame = +1
Query: 139 TKRWENATIVYQIVLTDFRKDEIDGLLNAMDIYQNETCLKFRTAKLSDPYSVIIRKGSGG 318
T++W N I Y ++ + E L + Y ++TC++F D + I K G
Sbjct: 118 TRKWPNGRIPY-VISNQYNDRERAVLARSFQAYHDKTCVRFVPRTAVDNDYLYIGK-IDG 175
Query: 319 CNAILGQDRKTGTQTVNLGIGCRWYGLFLHELGHTIGLHHEHQHPDRDTGVDVQWDNVDP 498
C + +G R G Q ++L GC Y +HEL H++G +HEH+ DRD + + W N+D
Sbjct: 176 CYSDVG--RAGGRQELSLDNGCLQYDTAIHELMHSVGFYHEHERWDRDEHITILWHNIDR 233
Query: 499 TMKVWFNTIDKNDVNMFGVPYDMQSVMHYGQWAFSKTDENGNPLTTIVAKDPEFQRYLYY 678
F +D + + +G YD S+MHY AFSK N T+VAK E +
Sbjct: 234 EAYDQFGKVDLAESSYYGQLYDYYSIMHYDSLAFSK-----NGFETMVAKQSEMTAVIGA 288
Query: 679 VWMKDLSFGDVKRINLMYKCN 741
D S D+ ++NLMY+C+
Sbjct: 289 A--IDFSPIDILKMNLMYQCS 307
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,801,099
Number of Sequences: 369166
Number of extensions: 2208849
Number of successful extensions: 5803
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5514
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5735
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8197207050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)