Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_028_C24 (613 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O08719|EVL_RAT Ena/vasodilator-stimulated phosphoprotein... 45 1e-04 sp|P70429|EVL_MOUSE Ena/vasodilator-stimulated phosphoprote... 45 2e-04 sp|Q9UI08|EVL_HUMAN Ena/vasodilator-stimulated phosphoprote... 44 2e-04 sp|Q9NJG9|SUZ12_DROME Polycomb protein Su(z)12 (Suppressor ... 39 0.010 sp|P50552|VASP_HUMAN Vasodilator-stimulated phosphoprotein ... 39 0.014 sp|O77459|KEN_DROME Probable transcription factor Ken (Ken ... 36 0.068 sp|P51612|XPC_MOUSE DNA-repair protein complementing XP-C c... 35 0.12 sp|P32583|SRP40_YEAST Suppressor protein SRP40 35 0.15 sp|P22810|HMOC_DROME Homeotic protein ocelliless (Orthodent... 35 0.20 sp|P74934|ENO_TREPA Enolase (2-phosphoglycerate dehydratase... 34 0.26
>sp|O08719|EVL_RAT Ena/vasodilator-stimulated phosphoprotein-like protein (Ena/VASP-like protein) Length = 393 Score = 45.1 bits (105), Expect = 1e-04 Identities = 38/124 (30%), Positives = 61/124 (49%), Gaps = 8/124 (6%) Frame = +3 Query: 159 EESNQSGLASQLRQAKLKSRGGPVEPDVSSNQNKNVTSSATLGRA----GGDSMMSEMQR 326 +ES+ SGLA+ L AKL+ P D S + + TS + RA GG +M EM + Sbjct: 214 DESSASGLAAALAGAKLRRVQRP--EDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNK 271 Query: 327 VLAARKK-AKEVVKPTGSECTDNGGSGDNSSKNPQWR---QNHHRSQSDCDQTNGTNNQS 494 +LA R+K A + KP + +N ++S +P R Q + S++ +N+ Sbjct: 272 LLAKRRKAASQTDKPADRKEDENQTEDPSTSPSPGSRATSQPPNSSEAGRKPWERSNSVE 331 Query: 495 KPAA 506 KP + Sbjct: 332 KPVS 335
>sp|P70429|EVL_MOUSE Ena/vasodilator-stimulated phosphoprotein-like protein (Ena/VASP-like protein) Length = 414 Score = 44.7 bits (104), Expect = 2e-04 Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 8/154 (5%) Frame = +3 Query: 159 EESNQSGLASQLRQAKLKSRGGPVEPDVSSNQNKNVTSSATLGRA----GGDSMMSEMQR 326 +ES+ SGLA+ L AKL+ P D S + + TS + RA GG +M EM + Sbjct: 214 DESSASGLAAALAGAKLRRVQRP--EDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNK 271 Query: 327 VLAARKK-AKEVVKPTGSECTDNGGSGDNSSKNPQWR---QNHHRSQSDCDQTNGTNNQS 494 +LA R+K A + KP + ++ ++S +P R Q + S++ +N+ Sbjct: 272 LLAKRRKAASQTDKPADRKEDESQTEDPSTSPSPGTRATSQPPNSSEAGRKPWERSNSVE 331 Query: 495 KPAADAAKSTSMQCATLGRRGSLQPDSQQPVSSI 596 KP + T + + LQ QP S + Sbjct: 332 KPVSSLLSRTPSVAKSPEAKSPLQ---SQPHSRV 362
>sp|Q9UI08|EVL_HUMAN Ena/vasodilator-stimulated phosphoprotein-like protein (Ena/VASP-like protein) Length = 416 Score = 44.3 bits (103), Expect = 2e-04 Identities = 44/159 (27%), Positives = 74/159 (46%), Gaps = 11/159 (6%) Frame = +3 Query: 153 SDEESNQSGLASQLRQAKLKSRGGPVEPDVSSNQNKNVTSSATLGRA----GGDSMMSEM 320 S +ES+ SGLA+ + AKL+ P D S + + TS + RA GG +M EM Sbjct: 214 SHDESSMSGLAAAIAGAKLRRVQRP--EDASGGSSPSGTSKSDANRASSGGGGGGLMEEM 271 Query: 321 QRVLAARKK-AKEVVKPTGSECTDNGGSGDNSSKNPQWR---QNHHRSQSDCDQTNGTNN 488 ++LA R+K A + KP + ++ ++S +P R Q + S++ +N+ Sbjct: 272 NKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNS 331 Query: 489 QSKPAADAAKSTSMQCATLGRRGSL--QPDSQ-QPVSSI 596 KP + T + + L QP S+ +P S+ Sbjct: 332 VEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRMKPAGSV 370
>sp|Q9NJG9|SUZ12_DROME Polycomb protein Su(z)12 (Suppressor 12 of zeste protein) Length = 900 Score = 38.9 bits (89), Expect = 0.010 Identities = 32/139 (23%), Positives = 56/139 (40%), Gaps = 1/139 (0%) Frame = +3 Query: 144 NNDSDEESNQSGLASQLRQAKLKSRGGPVEPDVSSNQNKNVTSSATLGR-AGGDSMMSEM 320 N + SN +A + L + E Q +NV+ S A + S+ Sbjct: 746 NGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKD 805 Query: 321 QRVLAARKKAKEVVKPTGSECTDNGGSGDNSSKNPQWRQNHHRSQSDCDQTNGTNNQSKP 500 VL R++ + TG GGSG +++N + N+H + + + +++ SK Sbjct: 806 NTVLNKRQRYSDGSPGTGIGNGHGGGSGSGANRN---KSNNHSLPATSNNASSSSSNSKR 862 Query: 501 AADAAKSTSMQCATLGRRG 557 A +STS + G G Sbjct: 863 AIARRRSTSERTKASGSTG 881
Score = 33.5 bits (75), Expect = 0.44 Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Frame = +3 Query: 195 RQAKLKSRGGPVEPDVSSNQNKNVTSSATLGRAGGDSMMSEMQRVLAARKKAKEVVKP-T 371 +Q K+ P +P ++Q + +S++T G G S M +R+ A K+ P Sbjct: 678 KQEDPKTLKSPQKPAPPADQ-ASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGV 736 Query: 372 GSECTDNGGSGDNSSKN 422 S+ T+NG +G NSS + Sbjct: 737 QSKGTENGTNGSNSSSS 753
>sp|P50552|VASP_HUMAN Vasodilator-stimulated phosphoprotein (VASP) Length = 380 Score = 38.5 bits (88), Expect = 0.014 Identities = 32/130 (24%), Positives = 54/130 (41%), Gaps = 13/130 (10%) Frame = +3 Query: 177 GLASQLRQAKLK-------SRGGPVEPDVSSNQNKNVTSSATLGRAGGDSMMSEMQRVLA 335 GLA+ + AKL+ + GGP P S GR+GG +M EM +LA Sbjct: 225 GLAAAIAGAKLRKVSKQEEASGGPTAPKAES------------GRSGGGGLMEEMNAMLA 272 Query: 336 ARKKAKEVVKPTGSECTDNGGS------GDNSSKNPQWRQNHHRSQSDCDQTNGTNNQSK 497 R+KA +V + T + + N + S W +N ++ T ++++ Sbjct: 273 RRRKATQVGEKTPKDESANQEEPEARVPAQSESVRRPWEKNSTTLPRMKSSSSVTTSETQ 332 Query: 498 PAADAAKSTS 527 P ++ S Sbjct: 333 PCTPSSSDYS 342
>sp|O77459|KEN_DROME Probable transcription factor Ken (Ken and Barbie protein) Length = 601 Score = 36.2 bits (82), Expect = 0.068 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 7/93 (7%) Frame = +3 Query: 249 NQNKNVTSSATLGRAGGDSMMSEMQRVLAAR-----KKAKEVVKPTGSECTDNGGSGDN- 410 N N N S+A R+GG + E + + K E+V + + + GS N Sbjct: 180 NSNDNCESAAECERSGGHNNKEEDEDDCTHKDNKSDKDTDEIVNLSNAPPSGTSGSNSNI 239 Query: 411 -SSKNPQWRQNHHRSQSDCDQTNGTNNQSKPAA 506 +S N Q +Q+HH + + N NN + ++ Sbjct: 240 STSSNHQQQQHHHHHHHNHNNNNNNNNNNSSSS 272
>sp|P51612|XPC_MOUSE DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C complementing protein homolog) (p125) Length = 930 Score = 35.4 bits (80), Expect = 0.12 Identities = 36/155 (23%), Positives = 60/155 (38%) Frame = +3 Query: 129 KPFQQNNDSDEESNQSGLASQLRQAKLKSRGGPVEPDVSSNQNKNVTSSATLGRAGGDSM 308 KP +EE+ G + K +RG S Q + + S G+ Sbjct: 355 KPTTSRRIKEEETLSEG------RGKATARGKRGTGTAGSRQRRKPSCSE------GEEA 402 Query: 309 MSEMQRVLAARKKAKEVVKPTGSECTDNGGSGDNSSKNPQWRQNHHRSQSDCDQTNGTNN 488 ++Q ARK+ + K + E +++ G+G S P + H S DC+ G Sbjct: 403 EQKVQGRPHARKR-RVAAKVSYKEESESDGAGSGSDFEPSSGEGQHSSDEDCEP--GPRK 459 Query: 489 QSKPAADAAKSTSMQCATLGRRGSLQPDSQQPVSS 593 Q + +A + A+ +RGS S P +S Sbjct: 460 QKRASAPQRTKAGSKSASKTQRGSQCEPSSFPEAS 494
>sp|P32583|SRP40_YEAST Suppressor protein SRP40 Length = 406 Score = 35.0 bits (79), Expect = 0.15 Identities = 26/140 (18%), Positives = 65/140 (46%), Gaps = 1/140 (0%) Frame = +3 Query: 111 STITMAKPFQQNNDSDEESNQSGLASQLRQ-AKLKSRGGPVEPDVSSNQNKNVTSSATLG 287 S+ + + + +++SD +S+ S +S + S + D SS+ + + + S + Sbjct: 179 SSSSSSSDSESDSESDSQSSSSSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDS 238 Query: 288 RAGGDSMMSEMQRVLAARKKAKEVVKPTGSECTDNGGSGDNSSKNPQWRQNHHRSQSDCD 467 + DS S ++ + + + T S+ +D+ D+ S + + +S + Sbjct: 239 DSSSDSDSSGSSDSSSSSDSSSD--ESTSSDSSDSDSDSDSGSSSELETKEATADESKAE 296 Query: 468 QTNGTNNQSKPAADAAKSTS 527 +T ++N+S P+A ++ S + Sbjct: 297 ETPASSNESTPSASSSSSAN 316
>sp|P22810|HMOC_DROME Homeotic protein ocelliless (Orthodenticle protein) Length = 671 Score = 34.7 bits (78), Expect = 0.20 Identities = 26/114 (22%), Positives = 42/114 (36%) Frame = +3 Query: 198 QAKLKSRGGPVEPDVSSNQNKNVTSSATLGRAGGDSMMSEMQRVLAARKKAKEVVKPTGS 377 Q K+R + Q N SS+ GG +A ++ + S Sbjct: 118 QVWFKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSS---SANSRSNSNNNGSSS 174 Query: 378 ECTDNGGSGDNSSKNPQWRQNHHRSQSDCDQTNGTNNQSKPAADAAKSTSMQCA 539 G+NS+K+ Q + N SQ + G N+ + AA AA + + A Sbjct: 175 NNNTQSSGGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNNNSAAAAASAAAAVAA 228
>sp|P74934|ENO_TREPA Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase) Length = 432 Score = 34.3 bits (77), Expect = 0.26 Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 1/112 (0%) Frame = +3 Query: 207 LKSRGGP-VEPDVSSNQNKNVTSSATLGRAGGDSMMSEMQRVLAARKKAKEVVKPTGSEC 383 + SRG P VE DVS + + G + G+ EM+ R K V+K G+ Sbjct: 13 IDSRGNPTVEVDVSLSDGSFGRACVPSGASTGEFEALEMRDGDKERYNGKGVLKAVGTVN 72 Query: 384 TDNGGSGDNSSKNPQWRQNHHRSQSDCDQTNGTNNQSKPAADAAKSTSMQCA 539 T + + Q +H D GT+N+SK A+A SM CA Sbjct: 73 TLIADTLEGMDALNQGEIDHAMRNLD-----GTDNKSKLGANAMLGVSMACA 119
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 64,303,207 Number of Sequences: 369166 Number of extensions: 1255050 Number of successful extensions: 4168 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3930 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4133 length of database: 68,354,980 effective HSP length: 105 effective length of database: 48,957,805 effective search space used: 4797864890 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)