Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_C07
(748 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9W734|SMAD6_CHICK Mothers against decapentaplegic homol... 41 0.004
sp|O43541|SMAD6_HUMAN Mothers against decapentaplegic homol... 40 0.009
sp|O35182|SMAD6_MOUSE Mothers against decapentaplegic homol... 40 0.009
sp|O35253|SMAD7_MOUSE Mothers against decapentaplegic homol... 39 0.015
sp|O15105|SMAD7_HUMAN Mothers against decapentaplegic homol... 39 0.015
sp|O88406|SMAD7_RAT Mothers against decapentaplegic homolog... 39 0.015
sp|Q9JIW5|SMAD9_MOUSE Mothers against decapentaplegic homol... 36 0.13
sp|O15198|SMAD9_HUMAN Mothers against decapentaplegic homol... 36 0.13
sp|Q15796|SMAD2_HUMAN Mothers against decapentaplegic homol... 34 0.36
sp|P84022|SMAD3_HUMAN Mothers against decapentaplegic homol... 34 0.36
>sp|Q9W734|SMAD6_CHICK Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against
DPP homolog 6) (Smad6)
Length = 431
Score = 40.8 bits (94), Expect = 0.004
Identities = 34/96 (35%), Positives = 45/96 (46%)
Frame = +1
Query: 232 HNKESKPVFISSATLQEDAFSSGKWPVVRVAAGQSILAFNTKLFANLLQSETETRPGQLP 411
+N+ P+F++S TL D + V +V G SI F+ + LLQ E P
Sbjct: 337 YNRSEHPIFVNSPTL--DIPNCRTLIVRKVMPGYSIKVFDYEKSC-LLQHTAELDYADGP 393
Query: 412 LLRSAVIHISPQKGWGPGYKRVQFIQCPIRYEIWLS 519
++V IS KGWGP Y R CP EI LS
Sbjct: 394 YDPNSV-RISFAKGWGPCYSRQFITSCPCWLEILLS 428
>sp|O43541|SMAD6_HUMAN Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against
DPP homolog 6) (Smad6) (hSMAD6)
Length = 496
Score = 39.7 bits (91), Expect = 0.009
Identities = 33/96 (34%), Positives = 44/96 (45%)
Frame = +1
Query: 232 HNKESKPVFISSATLQEDAFSSGKWPVVRVAAGQSILAFNTKLFANLLQSETETRPGQLP 411
+N+ P+F++S TL DA V +V G SI F+ + LQ E P
Sbjct: 403 YNRGEHPIFVNSPTL--DAPGGRALVVRKVPPGYSIKVFDFERSG--LQHAPEPDAADGP 458
Query: 412 LLRSAVIHISPQKGWGPGYKRVQFIQCPIRYEIWLS 519
++V IS KGWGP Y R CP EI L+
Sbjct: 459 YDPNSV-RISFAKGWGPCYSRQFITSCPCWLEILLN 493
>sp|O35182|SMAD6_MOUSE Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against
DPP homolog 6) (Smad6) (Mad homolog 7)
Length = 495
Score = 39.7 bits (91), Expect = 0.009
Identities = 31/96 (32%), Positives = 43/96 (44%)
Frame = +1
Query: 232 HNKESKPVFISSATLQEDAFSSGKWPVVRVAAGQSILAFNTKLFANLLQSETETRPGQLP 411
+N+ P+F++S TL DA V +V G SI F+ + L ++ P
Sbjct: 404 YNRGEHPIFVNSPTL--DAPGGRALVVRKVPPGYSIKVFDFERSGLLQHADAAHGPYDPH 461
Query: 412 LLRSAVIHISPQKGWGPGYKRVQFIQCPIRYEIWLS 519
+R IS KGWGP Y R CP EI L+
Sbjct: 462 SVR-----ISFAKGWGPCYSRQFITSCPCWLEILLN 492
>sp|O35253|SMAD7_MOUSE Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against
DPP homolog 7) (Smad7) (Madh8)
Length = 426
Score = 38.9 bits (89), Expect = 0.015
Identities = 37/104 (35%), Positives = 49/104 (47%)
Frame = +1
Query: 199 LELELSGNILLHNKESKPVFISSATLQEDAFSSGKWPVVRVAAGQSILAFNTKLFANLLQ 378
L E+ G + ++N+ S P+FI SATL D S V +V G SI AF+ + A LQ
Sbjct: 323 LTREVDG-VWVYNRSSYPIFIKSATL--DNPDSRTLLVHKVFPGFSIKAFDYEK-AYSLQ 378
Query: 379 SETETRPGQLPLLRSAVIHISPQKGWGPGYKRVQFIQCPIRYEI 510
+ Q P + IS KGWG Y R CP E+
Sbjct: 379 RPNDHEFMQQPWT-GFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
>sp|O15105|SMAD7_HUMAN Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against
DPP homolog 7) (Smad7) (hSMAD7)
Length = 426
Score = 38.9 bits (89), Expect = 0.015
Identities = 37/104 (35%), Positives = 49/104 (47%)
Frame = +1
Query: 199 LELELSGNILLHNKESKPVFISSATLQEDAFSSGKWPVVRVAAGQSILAFNTKLFANLLQ 378
L E+ G + ++N+ S P+FI SATL D S V +V G SI AF+ + A LQ
Sbjct: 323 LTREVDG-VWVYNRSSYPIFIKSATL--DNPDSRTLLVHKVFPGFSIKAFDYEK-AYSLQ 378
Query: 379 SETETRPGQLPLLRSAVIHISPQKGWGPGYKRVQFIQCPIRYEI 510
+ Q P + IS KGWG Y R CP E+
Sbjct: 379 RPNDHEFMQQPWT-GFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
>sp|O88406|SMAD7_RAT Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against
DPP homolog 7) (Smad7)
Length = 426
Score = 38.9 bits (89), Expect = 0.015
Identities = 37/104 (35%), Positives = 49/104 (47%)
Frame = +1
Query: 199 LELELSGNILLHNKESKPVFISSATLQEDAFSSGKWPVVRVAAGQSILAFNTKLFANLLQ 378
L E+ G + ++N+ S P+FI SATL D S V +V G SI AF+ + A LQ
Sbjct: 323 LTREVDG-VWVYNRSSYPIFIKSATL--DNPDSRTLLVHKVFPGFSIKAFDYEK-AYSLQ 378
Query: 379 SETETRPGQLPLLRSAVIHISPQKGWGPGYKRVQFIQCPIRYEI 510
+ Q P + IS KGWG Y R CP E+
Sbjct: 379 RPNDHEFMQQPWT-GFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
>sp|Q9JIW5|SMAD9_MOUSE Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against
DPP homolog 9) (Smad9) (Smad8)
Length = 430
Score = 35.8 bits (81), Expect = 0.13
Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 1/70 (1%)
Frame = +1
Query: 310 VVRVAAGQSILAFNTKLFANLL-QSETETRPGQLPLLRSAVIHISPQKGWGPGYKRVQFI 486
V ++ +G S+ FN +LFA LL QS L + I +S KGWG Y R
Sbjct: 336 VCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVT 395
Query: 487 QCPIRYEIWL 516
P EI L
Sbjct: 396 STPCWIEIHL 405
>sp|O15198|SMAD9_HUMAN Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against
DPP homolog 9) (Smad9) (Madh6)
Length = 467
Score = 35.8 bits (81), Expect = 0.13
Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 1/70 (1%)
Frame = +1
Query: 310 VVRVAAGQSILAFNTKLFANLL-QSETETRPGQLPLLRSAVIHISPQKGWGPGYKRVQFI 486
V ++ +G S+ FN +LFA LL QS L + I +S KGWG Y R
Sbjct: 373 VCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVT 432
Query: 487 QCPIRYEIWL 516
P EI L
Sbjct: 433 STPCWIEIHL 442
>sp|Q15796|SMAD2_HUMAN Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against
DPP homolog 2) (Mad-related protein 2) (hMAD-2) (JV18-1)
(hSMAD2)
Length = 467
Score = 34.3 bits (77), Expect = 0.36
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Frame = +1
Query: 310 VVRVAAGQSILAFNTKLFANLL-QSETETRPGQLPLLRSAVIHISPQKGWGPGYKRVQFI 486
V ++ G ++ FN + FA LL QS + L R I +S KGWG Y+R
Sbjct: 373 VCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVT 432
Query: 487 QCPIRYEIWLS 519
P E+ L+
Sbjct: 433 STPCWIELHLN 443
>sp|P84022|SMAD3_HUMAN Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against
DPP homolog 3) (Mad3) (hMAD-3) (JV15-2) (hSMAD3)
sp|P84025|SMAD3_RAT Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against
DPP homolog 3) (Mad3)
sp|P84024|SMAD3_PIG Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against
DPP homolog 3) (Mad3)
sp|Q8BUN5|SMAD3_MOUSE Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against
DPP homolog 3) (Mad3) (mMad3)
Length = 425
Score = 34.3 bits (77), Expect = 0.36
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Frame = +1
Query: 310 VVRVAAGQSILAFNTKLFANLL-QSETETRPGQLPLLRSAVIHISPQKGWGPGYKRVQFI 486
V ++ G ++ FN + FA LL QS + L R I +S KGWG Y+R
Sbjct: 331 VCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVT 390
Query: 487 QCPIRYEIWLS 519
P E+ L+
Sbjct: 391 STPCWIELHLN 401
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,494,244
Number of Sequences: 369166
Number of extensions: 1800157
Number of successful extensions: 4597
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4474
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4593
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6776504000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)