Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_028_C01 (337 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P35034|TRYP_PLEPL Trypsin precursor 65 5e-11 sp|P32038|CFAD_RAT Complement factor D precursor (C3 conver... 60 1e-09 sp|P32822|TRYB_RAT Trypsin V-B precursor 60 1e-09 sp|P32821|TRYA_RAT Trypsin V-A precursor 60 1e-09 sp|P03953|CFAD_MOUSE Complement factor D precursor (C3 conv... 60 2e-09 sp|P51779|CFAD_PIG Complement factor D precursor (C3 conver... 60 2e-09 sp|P47796|CTRA_GADMO Chymotrypsin A precursor 58 6e-09 sp|P40313|CTRL_HUMAN Chymotrypsin-like protease CTRL-1 prec... 57 1e-08 sp|P80646|CTRB_GADMO Chymotrypsin B [Contains: Chymotrypsin... 57 1e-08 sp|Q29463|TRY2_BOVIN Anionic trypsin precursor 57 1e-08
>sp|P35034|TRYP_PLEPL Trypsin precursor Length = 250 Score = 65.1 bits (157), Expect = 5e-11 Identities = 34/93 (36%), Positives = 50/93 (53%) Frame = +3 Query: 48 KIINGSQAIMHEYPQMVSIKVQGNHFCGGTLLNGNTVLTAAHCVWDMRNWDVNTFKYYQM 227 +II G + H P M S+ G HFCGG L+N VL+ AHC W + Y M Sbjct: 22 RIIGGHECAAHSRPFMASLNY-GYHFCGGVLINNQWVLSVAHC-W---------YNPYAM 70 Query: 228 KVYMGEYDLYRMYGVEKIFQVTKTIIHPSYRHE 326 +V +GE+DL + G E++ + I HP+Y ++ Sbjct: 71 QVMLGEHDLRKFEGTEQLMKTDTIIWHPNYDYQ 103
>sp|P32038|CFAD_RAT Complement factor D precursor (C3 convertase activator) (Properdin factor D) (Adipsin) (Endogenous vascular elastase) Length = 263 Score = 60.5 bits (145), Expect = 1e-09 Identities = 30/98 (30%), Positives = 51/98 (52%) Frame = +3 Query: 27 CAVTSGWKIINGSQAIMHEYPQMVSIKVQGNHFCGGTLLNGNTVLTAAHCVWDMRNWDVN 206 C +I+ G +A+ H P M S++V G H CGGTL++ VL+AAHC+ + +V Sbjct: 18 CVAQPRGRILGGQEAMAHARPYMASVQVNGTHVCGGTLVDEQWVLSAAHCMDGVTKDEV- 76 Query: 207 TFKYYQMKVYMGEYDLYRMYGVEKIFQVTKTIIHPSYR 320 ++V +G + L + ++ V ++HP R Sbjct: 77 ------VQVLLGAHSLSSPEPYKHLYDVQSVVLHPGSR 108
>sp|P32822|TRYB_RAT Trypsin V-B precursor Length = 246 Score = 60.5 bits (145), Expect = 1e-09 Identities = 30/90 (33%), Positives = 47/90 (52%) Frame = +3 Query: 48 KIINGSQAIMHEYPQMVSIKVQGNHFCGGTLLNGNTVLTAAHCVWDMRNWDVNTFKYYQM 227 +I+ G H P VS+ G+H CGG+L+ VL+AAHC + Q+ Sbjct: 24 RIVGGYTCQEHSVPYQVSLNA-GSHICGGSLITDQWVLSAAHCY------------HPQL 70 Query: 228 KVYMGEYDLYRMYGVEKIFQVTKTIIHPSY 317 +V +GE+++Y + G E+ K I+HP Y Sbjct: 71 QVRLGEHNIYEIEGAEQFIDAAKMILHPDY 100
>sp|P32821|TRYA_RAT Trypsin V-A precursor Length = 246 Score = 60.5 bits (145), Expect = 1e-09 Identities = 30/90 (33%), Positives = 47/90 (52%) Frame = +3 Query: 48 KIINGSQAIMHEYPQMVSIKVQGNHFCGGTLLNGNTVLTAAHCVWDMRNWDVNTFKYYQM 227 +I+ G H P VS+ G+H CGG+L+ VL+AAHC + Q+ Sbjct: 24 RIVGGYTCQEHSVPYQVSLNA-GSHICGGSLITDQWVLSAAHCY------------HPQL 70 Query: 228 KVYMGEYDLYRMYGVEKIFQVTKTIIHPSY 317 +V +GE+++Y + G E+ K I+HP Y Sbjct: 71 QVRLGEHNIYEIEGAEQFIDAAKMILHPDY 100
>sp|P03953|CFAD_MOUSE Complement factor D precursor (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa protein, adipocyte) Length = 259 Score = 60.1 bits (144), Expect = 2e-09 Identities = 32/98 (32%), Positives = 50/98 (51%) Frame = +3 Query: 27 CAVTSGWKIINGSQAIMHEYPQMVSIKVQGNHFCGGTLLNGNTVLTAAHCVWDMRNWDVN 206 CA +I+ G +A H P M S++V G H CGGTLL+ VL+AAHC+ + + D Sbjct: 18 CAAQPRGRILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDD-- 75 Query: 207 TFKYYQMKVYMGEYDLYRMYGVEKIFQVTKTIIHPSYR 320 ++V +G + L ++ + V + HP R Sbjct: 76 -----SVQVLLGAHSLSAPEPYKRWYDVQSVVPHPGSR 108
>sp|P51779|CFAD_PIG Complement factor D precursor (C3 convertase activator) (Properdin factor D) (Adipsin) Length = 259 Score = 59.7 bits (143), Expect = 2e-09 Identities = 29/95 (30%), Positives = 51/95 (53%) Frame = +3 Query: 27 CAVTSGWKIINGSQAIMHEYPQMVSIKVQGNHFCGGTLLNGNTVLTAAHCVWDMRNWDVN 206 C +I+ G +A HE P M S++V G H CGG L++ VL+AAHC+ D+ Sbjct: 19 CVAQPRGRILGGQEAKSHERPYMASVQVNGKHVCGGFLVSEQWVLSAAHCLEDVAEG--- 75 Query: 207 TFKYYQMKVYMGEYDLYRMYGVEKIFQVTKTIIHP 311 +++V +G + L + ++++ V + + HP Sbjct: 76 -----KLQVLLGAHSLSQPEPSKRLYDVLRAVPHP 105
>sp|P47796|CTRA_GADMO Chymotrypsin A precursor Length = 263 Score = 58.2 bits (139), Expect = 6e-09 Identities = 34/96 (35%), Positives = 52/96 (54%), Gaps = 1/96 (1%) Frame = +3 Query: 33 VTSGWKIINGSQAIMHEYPQMVSIKVQ-GNHFCGGTLLNGNTVLTAAHCVWDMRNWDVNT 209 +T +I+NG +A+ H + VS++ Q G HFCGG+L+N N V+TAAHC N Sbjct: 28 ITGYSRIVNGEEAVPHSWSWQVSLQDQTGFHFCGGSLINENWVVTAAHC---------NV 78 Query: 210 FKYYQMKVYMGEYDLYRMYGVEKIFQVTKTIIHPSY 317 Y+ +V +GE+D ++ V + HP Y Sbjct: 79 KNYH--RVVLGEHDRSSNSEGVQVMTVGQVFKHPRY 112
>sp|P40313|CTRL_HUMAN Chymotrypsin-like protease CTRL-1 precursor Length = 264 Score = 57.4 bits (137), Expect = 1e-08 Identities = 32/97 (32%), Positives = 57/97 (58%), Gaps = 1/97 (1%) Frame = +3 Query: 30 AVTSGWKIINGSQAIMHEYPQMVSIK-VQGNHFCGGTLLNGNTVLTAAHCVWDMRNWDVN 206 A++ +I+NG A++ +P VS++ G HFCGG+L++ + V+TAAHC +V+ Sbjct: 27 ALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHC-------NVS 79 Query: 207 TFKYYQMKVYMGEYDLYRMYGVEKIFQVTKTIIHPSY 317 +++ V +GEYD ++ V++ I HPS+ Sbjct: 80 PGRHF---VVLGEYDRSSNAEPLQVLSVSRAITHPSW 113
>sp|P80646|CTRB_GADMO Chymotrypsin B [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B] Length = 245 Score = 57.4 bits (137), Expect = 1e-08 Identities = 34/96 (35%), Positives = 54/96 (56%), Gaps = 1/96 (1%) Frame = +3 Query: 33 VTSGWKIINGSQAIMHEYPQMVSIKVQ-GNHFCGGTLLNGNTVLTAAHCVWDMRNWDVNT 209 VT +I+NG +A+ H +P VS++ G HFCGG+L+N N V+TAAHC +V T Sbjct: 10 VTGYARIVNGEEAVPHSWPWQVSLQQSNGFHFCGGSLINENWVVTAAHC-------NVRT 62 Query: 210 FKYYQMKVYMGEYDLYRMYGVEKIFQVTKTIIHPSY 317 + +V +GE+D ++ I + + HP + Sbjct: 63 YH----RVIVGEHDKASDENIQ-ILKPSMVFTHPKW 93
>sp|Q29463|TRY2_BOVIN Anionic trypsin precursor Length = 247 Score = 57.0 bits (136), Expect = 1e-08 Identities = 31/90 (34%), Positives = 46/90 (51%) Frame = +3 Query: 48 KIINGSQAIMHEYPQMVSIKVQGNHFCGGTLLNGNTVLTAAHCVWDMRNWDVNTFKYYQM 227 KI+ G + P VS+ G HFCGG+L+N V++AAHC Y + Sbjct: 23 KIVGGYTCAENSVPYQVSLNA-GYHFCGGSLINDQWVVSAAHCY------------QYHI 69 Query: 228 KVYMGEYDLYRMYGVEKIFQVTKTIIHPSY 317 +V +GEY++ + G E+ +K I HP Y Sbjct: 70 QVRLGEYNIDVLEGGEQFIDASKIIRHPKY 99
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 44,162,773 Number of Sequences: 369166 Number of extensions: 877567 Number of successful extensions: 2366 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2257 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2288 length of database: 68,354,980 effective HSP length: 79 effective length of database: 53,760,915 effective search space used: 1720349280 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)