Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_P13-1
(414 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q61830|MANR1_MOUSE Macrophage mannose receptor 1 precurs... 59 5e-09
sp|P23805|CONG_BOVIN Conglutinin precursor 58 9e-09
sp|Q28343|PGCA_CANFA Aggrecan core protein precursor (Carti... 57 1e-08
sp|P13611|CSPG2_HUMAN Versican core protein precursor (Larg... 57 2e-08
sp|P81282|CSPG2_BOVIN Versican core protein precursor (Larg... 57 2e-08
sp||Q9ERB4_2 [Segment 2 of 2] Versican core protein precurs... 57 2e-08
sp|Q62059|CSPG2_MOUSE Versican core protein precursor (Larg... 57 2e-08
sp|Q90953|CSPG2_CHICK Versican core protein precursor (Larg... 56 3e-08
sp|P22897|MANR1_HUMAN Macrophage mannose receptor precursor... 56 3e-08
sp|O75596|CLC3A_HUMAN C-type lectin domain family 3 member ... 56 3e-08
>sp|Q61830|MANR1_MOUSE Macrophage mannose receptor 1 precursor (MMR)
Length = 1456
Score = 58.5 bits (140), Expect = 5e-09
Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
Frame = -3
Query: 370 EDSGYQFTKDRMNHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGSYWINGNDIG 191
+D Y F+K++ D+A ++C+ L TI +++ K ++ K G S + G I
Sbjct: 808 KDYQYYFSKEKETMDNARRFCKKNFGDLATIKSESEKKFLWKYINKNGGQSPYFIGMLIS 867
Query: 190 YESDWKNTDGELIKFKPWHQVEPN-GGRGENCIHGLFYPNGIWNDVSCASTQAVICQ 23
+ + DG + F W EPN ENC+ ++ +G WND++C ICQ
Sbjct: 868 MDKKFIWMDGSKVDFVAWATGEPNFANDDENCVT-MYTNSGFWNDINCGYPNNFICQ 923
Score = 37.0 bits (84), Expect = 0.016
Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 9/117 (7%)
Frame = -3
Query: 346 KDRMNHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGSYWINGNDIGYESDWKNT 167
+++ + DA + C+ L +I+N A + ++ + W NDI E + T
Sbjct: 964 EEKKSWQDARQACKGLKGNLVSIEN-AQEQAFVTYHMRDSTFNAWTGLNDINAEHMFLWT 1022
Query: 166 DGELIKFKPWHQVEPNGGRGE------NC---IHGLFYPNGIWNDVSCASTQAVICQ 23
G+ + + W + P G R +C I G G W D +C S Q ICQ
Sbjct: 1023 AGQGVHYTNWGKGYPGGRRSSLSYEDADCVVVIGGNSREAGTWMDDTCDSKQGYICQ 1079
Score = 36.2 bits (82), Expect = 0.027
Identities = 23/110 (20%), Positives = 44/110 (40%), Gaps = 1/110 (0%)
Frame = -3
Query: 349 TKDRMNHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGS-YWINGNDIGYESDWK 173
+K + A C+ +N L ++ ++ +Y + L S WI N + S W+
Sbjct: 234 SKSALTWHQARASCKQQNADLLSVTE--IHEQMYLTGLTSSLSSGLWIGLNSLSVRSGWQ 291
Query: 172 NTDGELIKFKPWHQVEPNGGRGENCIHGLFYPNGIWNDVSCASTQAVICQ 23
G ++ W P+ G++C+ N W ++ C IC+
Sbjct: 292 WAGGSPFRYLNWLPGSPSSEPGKSCVSLNPGKNAKWENLECVQKLGYICK 341
Score = 35.8 bits (81), Expect = 0.035
Identities = 18/66 (27%), Positives = 33/66 (50%)
Frame = -3
Query: 220 SYWINGNDIGYESDWKNTDGELIKFKPWHQVEPNGGRGENCIHGLFYPNGIWNDVSCAST 41
++WI G E W + + F W +P+G R + + L +G+WN++ C+S
Sbjct: 1293 NFWI-GMFRNVEGKWLWLNDNPVSFVNWKTGDPSGERNDCVV--LASSSGLWNNIHCSSY 1349
Query: 40 QAVICQ 23
+ IC+
Sbjct: 1350 KGFICK 1355
Score = 34.3 bits (77), Expect = 0.10
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Frame = -3
Query: 214 WINGNDIGYESDWKNTDGELIKFKPWHQVEPN--GGRGENCIHGLFYPNGIWNDVSCAST 41
WI NDI + ++ +DG + F W EP+ R E+C+ + +G W D +C
Sbjct: 423 WIGLNDIKIQMYFEWSDGTPVTFTKWLPGEPSHENNRQEDCV-VMKGKDGYWADRACEQP 481
Query: 40 QAVICQ 23
IC+
Sbjct: 482 LGYICK 487
Score = 34.3 bits (77), Expect = 0.10
Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 6/103 (5%)
Frame = -3
Query: 313 YCRAKNMKLPTIDNDATNKVVYDIAVKYGLGS--YWINGNDIGYESD---WKNTDGELIK 149
+C+A +L +I + +V++ + G +W+ G G S+ W +DG +
Sbjct: 679 FCKAIGGELASIKSKDEQQVIWRLITSSGSYHELFWL-GLTYGSPSEGFTW--SDGSPVS 735
Query: 148 FKPWHQVEPNGGRG-ENCIHGLFYPNGIWNDVSCASTQAVICQ 23
++ W EPN + E C P WND++C ICQ
Sbjct: 736 YENWAYGEPNNYQNVEYCGELKGDPGMSWNDINCEHLNNWICQ 778
>sp|P23805|CONG_BOVIN Conglutinin precursor
Length = 371
Score = 57.8 bits (138), Expect = 9e-09
Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Frame = -3
Query: 334 NHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGSYWINGNDIGYESDWKNTDGEL 155
++ DA + CR +L + + A N+ V + +Y ++ NDI E + GE+
Sbjct: 267 SYSDAEQLCREAKGQLASPRSSAENEAVTQMVRAQEKNAY-LSMNDISTEGRFTYPTGEI 325
Query: 154 IKFKPWHQVEPNG---GRGENCIHGLFYPNGIWNDVSCASTQAVICQ 23
+ + W EPN G+ ENC+ +P+G WNDV C+ VIC+
Sbjct: 326 LVYSNWADGEPNNSDEGQPENCVE--IFPDGKWNDVPCSKQLLVICE 370
>sp|Q28343|PGCA_CANFA Aggrecan core protein precursor (Cartilage-specific proteoglycan core
protein) (CSPCP)
Length = 2333
Score = 57.0 bits (136), Expect = 1e-08
Identities = 33/105 (31%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = -3
Query: 358 YQFTKDRMNHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGSYWINGNDIGYESD 179
Y++ DR + DA CRA+ L +I + V + A Y WI ND E D
Sbjct: 2135 YRYFPDRESWVDAESRCRAQQSHLSSIVTPEEQEFVNNNAQDY----QWIGLNDRTIEGD 2190
Query: 178 WKNTDGELIKFKPWHQVEPNG--GRGENCIHGLFYPNGIWNDVSC 50
++ +DG ++F+ W +P+ GE+C+ +++ G WNDV C
Sbjct: 2191 FRWSDGHSLQFENWRPNQPDNFFVSGEDCVVMIWHEKGEWNDVPC 2235
>sp|P13611|CSPG2_HUMAN Versican core protein precursor (Large fibroblast proteoglycan)
(Chondroitin sulfate proteoglycan core protein 2) (PG-M)
(Glial hyaluronate-binding protein) (GHAP)
Length = 3396
Score = 56.6 bits (135), Expect = 2e-08
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = -3
Query: 358 YQFTKDRMNHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGSYWINGNDIGYESD 179
Y++ R D A + CR + L +I + V + Y WI ND +E D
Sbjct: 3181 YKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDY----QWIGLNDKMFEHD 3236
Query: 178 WKNTDGELIKFKPWHQVEPNG--GRGENCIHGLFYPNGIWNDVSC 50
++ TDG ++++ W +P+ GE+C+ +++ NG WNDV C
Sbjct: 3237 FRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPC 3281
>sp|P81282|CSPG2_BOVIN Versican core protein precursor (Large fibroblast proteoglycan)
(Chondroitin sulfate proteoglycan core protein 2) (PG-M)
(Glial hyaluronate-binding protein) (GHAP)
Length = 3381
Score = 56.6 bits (135), Expect = 2e-08
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = -3
Query: 358 YQFTKDRMNHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGSYWINGNDIGYESD 179
Y++ R D A + CR + L +I + V + Y WI ND +E D
Sbjct: 3166 YKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDY----QWIGLNDKMFEHD 3221
Query: 178 WKNTDGELIKFKPWHQVEPNG--GRGENCIHGLFYPNGIWNDVSC 50
++ TDG ++++ W +P+ GE+C+ +++ NG WNDV C
Sbjct: 3222 FRWTDGSTLQYENWRPNQPDSFFSTGEDCVVIIWHENGQWNDVPC 3266
>sp||Q9ERB4_2 [Segment 2 of 2] Versican core protein precursor (Large fibroblast
proteoglycan) (Chondroitin sulfate proteoglycan core
protein 2) (PG-M) (Glial hyaluronate-binding protein)
(GHAP)
Length = 2390
Score = 56.6 bits (135), Expect = 2e-08
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = -3
Query: 358 YQFTKDRMNHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGSYWINGNDIGYESD 179
Y++ R D A + CR + L +I + V + Y WI ND +E D
Sbjct: 2175 YKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDY----QWIGLNDKMFEHD 2230
Query: 178 WKNTDGELIKFKPWHQVEPNG--GRGENCIHGLFYPNGIWNDVSC 50
++ TDG ++++ W +P+ GE+C+ +++ NG WNDV C
Sbjct: 2231 FRWTDGSALQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPC 2275
>sp|Q62059|CSPG2_MOUSE Versican core protein precursor (Large fibroblast proteoglycan)
(Chondroitin sulfate proteoglycan core protein 2) (PG-M)
Length = 3358
Score = 56.6 bits (135), Expect = 2e-08
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = -3
Query: 358 YQFTKDRMNHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGSYWINGNDIGYESD 179
Y++ R D A + CR + L +I + V + Y WI ND +E D
Sbjct: 3144 YKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDY----QWIGLNDKMFEHD 3199
Query: 178 WKNTDGELIKFKPWHQVEPNG--GRGENCIHGLFYPNGIWNDVSC 50
++ TDG ++++ W +P+ GE+C+ +++ NG WNDV C
Sbjct: 3200 FRWTDGSALQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPC 3244
>sp|Q90953|CSPG2_CHICK Versican core protein precursor (Large fibroblast proteoglycan)
(Chondroitin sulfate proteoglycan core protein 2) (PG-M)
Length = 3562
Score = 56.2 bits (134), Expect = 3e-08
Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = -3
Query: 358 YQFTKDRMNHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGSYWINGNDIGYESD 179
Y++ R D A + CR + L +I + V I Y WI ND +E D
Sbjct: 3346 YKYFAHRRTWDTAERECRLQGAHLTSILSHEEQVFVNRIGHDY----QWIGLNDKMFERD 3401
Query: 178 WKNTDGELIKFKPWHQVEPNG--GRGENCIHGLFYPNGIWNDVSC 50
++ TDG ++++ W +P+ GE+C+ +++ NG WNDV C
Sbjct: 3402 FRWTDGSPLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPC 3446
>sp|P22897|MANR1_HUMAN Macrophage mannose receptor precursor (MMR) (CD206 antigen)
Length = 1456
Score = 56.2 bits (134), Expect = 3e-08
Identities = 31/117 (26%), Positives = 56/117 (47%), Gaps = 1/117 (0%)
Frame = -3
Query: 370 EDSGYQFTKDRMNHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGSYWINGNDIG 191
+D Y F+K++ D+A +C+ L +I +++ K ++ + S + G I
Sbjct: 808 KDYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLIS 867
Query: 190 YESDWKNTDGELIKFKPWHQVEPN-GGRGENCIHGLFYPNGIWNDVSCASTQAVICQ 23
+ + DG + + W EPN ENC+ ++ +G WND++C A ICQ
Sbjct: 868 LDKKFAWMDGSKVDYVSWATGEPNFANEDENCVT-MYSNSGFWNDINCGYPNAFICQ 923
Score = 39.7 bits (91), Expect = 0.002
Identities = 25/110 (22%), Positives = 47/110 (42%), Gaps = 1/110 (0%)
Frame = -3
Query: 349 TKDRMNHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGS-YWINGNDIGYESDWK 173
+K + A K C+ +N +L +I ++ Y + L S WI N + + S W+
Sbjct: 234 SKSALTWHQARKSCQQQNAELLSITE--IHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQ 291
Query: 172 NTDGELIKFKPWHQVEPNGGRGENCIHGLFYPNGIWNDVSCASTQAVICQ 23
+D ++ W P+ G++C+ N W ++ C IC+
Sbjct: 292 WSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICK 341
Score = 39.7 bits (91), Expect = 0.002
Identities = 32/117 (27%), Positives = 47/117 (40%), Gaps = 9/117 (7%)
Frame = -3
Query: 346 KDRMNHDDAVKYCRAKNMKLPTIDNDATNKVVYDIAVKYGLGSYWINGNDIGYESDWKNT 167
++R N +A K C L +I N+ + +K S W ND+ E + T
Sbjct: 965 EERKNWQEARKACIGFGGNLVSIQNEK-EQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWT 1023
Query: 166 DGELIKFKPWHQVEPNGGRGE------NC---IHGLFYPNGIWNDVSCASTQAVICQ 23
DG + + W + P G R +C I G G W D +C S + ICQ
Sbjct: 1024 DGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQ 1080
Score = 36.2 bits (82), Expect = 0.027
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 6/103 (5%)
Frame = -3
Query: 313 YCRAKNMKLPTIDNDATNKVVYDIAVKYGLGS--YWINGNDIGYESD---WKNTDGELIK 149
+CRA L +I+N + ++ + G +W+ G G S+ W +DG +
Sbjct: 679 FCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWL-GLTYGSPSEGFTW--SDGSPVS 735
Query: 148 FKPWHQVEPNGGRG-ENCIHGLFYPNGIWNDVSCASTQAVICQ 23
++ W EPN + E C P WND++C ICQ
Sbjct: 736 YENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQ 778
Score = 35.8 bits (81), Expect = 0.035
Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Frame = -3
Query: 334 NHDDAVKYCRAKNMKLPTIDNDATNKVV-YDIAVKYGLGSYWINGNDIGYESDWKNTDGE 158
N A C L +I++ A + + Y + ++WI G E W +
Sbjct: 1255 NWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWI-GLFRNVEGTWLWINNS 1313
Query: 157 LIKFKPWHQVEPNGGRGENCIHGLFYPNGIWNDVSCASTQAVICQ 23
+ F W+ +P+G R + C+ L +G W+++ C+S + IC+
Sbjct: 1314 PVSFVNWNTGDPSGERND-CV-ALHASSGFWSNIHCSSYKGYICK 1356
Score = 33.5 bits (75), Expect = 0.17
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Frame = -3
Query: 214 WINGNDIGYESDWKNTDGELIKFKPWHQVEPN--GGRGENCIHGLFYPNGIWNDVSCAST 41
WI NDI + ++ +DG + F W + EP+ R E+C+ + +G W D C
Sbjct: 423 WIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCV-VMKGKDGYWADRGCEWP 481
Query: 40 QAVICQ 23
IC+
Sbjct: 482 LGYICK 487
>sp|O75596|CLC3A_HUMAN C-type lectin domain family 3 member A precursor (C-type lectin
superfamily member 1) (Cartilage-derived C-type lectin)
Length = 197
Score = 56.2 bits (134), Expect = 3e-08
Identities = 23/69 (33%), Positives = 39/69 (56%)
Frame = -3
Query: 229 GLGSYWINGNDIGYESDWKNTDGELIKFKPWHQVEPNGGRGENCIHGLFYPNGIWNDVSC 50
G+ +W+ ND+ E + + +G I F W + +PNGG+ ENC+ G W+D +C
Sbjct: 124 GVNDFWLGINDMVTEGKFVDVNGIAISFLNWDRAQPNGGKRENCVLFSQSAQGKWSDEAC 183
Query: 49 ASTQAVICQ 23
S++ IC+
Sbjct: 184 RSSKRYICE 192
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,032,591
Number of Sequences: 369166
Number of extensions: 1030939
Number of successful extensions: 3164
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2869
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3089
length of database: 68,354,980
effective HSP length: 99
effective length of database: 50,066,215
effective search space used: 1902516170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)