Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_P08
(792 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P67962|KC1A_CHICK Casein kinase I, alpha isoform (CKI-al... 394 e-109
sp|P48729|KC1A_HUMAN Casein kinase I, alpha isoform (CKI-al... 394 e-109
sp|P67829|KC1A_SHEEP Casein kinase I, alpha isoform (CKI-al... 394 e-109
sp|P97633|KC1A_RAT Casein kinase I, alpha isoform (CKI-alph... 393 e-109
sp|P42168|YKL1_CAEEL Putative casein kinase I C03C10.1 in c... 392 e-109
sp|Q8N752|KC1AL_HUMAN Casein kinase I, alpha-like isoform (... 376 e-104
sp|P54367|KC1A_DROME Casein kinase I, alpha isoform (CKI-al... 360 2e-99
sp|P40235|HHP1_SCHPO Casein kinase I homolog hhp1 349 4e-96
sp|P42158|KC1D_ARATH Casein kinase I, delta isoform-like (C... 346 4e-95
sp|Q06486|KC1D_RAT Casein kinase I, delta isoform (CKI-delt... 345 6e-95
>sp|P67962|KC1A_CHICK Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67963|KC1A_XENLA Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 337
Score = 394 bits (1012), Expect = e-109
Identities = 186/238 (78%), Positives = 212/238 (89%)
Frame = +3
Query: 78 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 257
+F+V K++LVRKIGSGSFGDIYL + ++NGEEVAVKLES ARHPQLLYESK+YK LQ
Sbjct: 10 EFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQG 69
Query: 258 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 437
GVGIP IRWYG + YN LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E+
Sbjct: 70 GVGIPHIRWYGQE---KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEY 126
Query: 438 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 617
+H+KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTAR
Sbjct: 127 VHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTAR 186
Query: 618 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTP 791
YASINAH GIEQSRRDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK STP
Sbjct: 187 YASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTP 244
>sp|P48729|KC1A_HUMAN Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|Q8BK63|KC1A_MOUSE Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 337
Score = 394 bits (1012), Expect = e-109
Identities = 186/238 (78%), Positives = 212/238 (89%)
Frame = +3
Query: 78 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 257
+F+V K++LVRKIGSGSFGDIYL + ++NGEEVAVKLES ARHPQLLYESK+YK LQ
Sbjct: 10 EFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQG 69
Query: 258 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 437
GVGIP IRWYG + YN LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E+
Sbjct: 70 GVGIPHIRWYGQE---KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEY 126
Query: 438 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 617
+H+KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTAR
Sbjct: 127 VHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTAR 186
Query: 618 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTP 791
YASINAH GIEQSRRDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK STP
Sbjct: 187 YASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTP 244
>sp|P67829|KC1A_SHEEP Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67828|KC1A_RABIT Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67827|KC1A_BOVIN Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 325
Score = 394 bits (1012), Expect = e-109
Identities = 186/238 (78%), Positives = 212/238 (89%)
Frame = +3
Query: 78 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 257
+F+V K++LVRKIGSGSFGDIYL + ++NGEEVAVKLES ARHPQLLYESK+YK LQ
Sbjct: 10 EFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQG 69
Query: 258 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 437
GVGIP IRWYG + YN LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E+
Sbjct: 70 GVGIPHIRWYGQE---KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEY 126
Query: 438 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 617
+H+KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTAR
Sbjct: 127 VHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTAR 186
Query: 618 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTP 791
YASINAH GIEQSRRDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK STP
Sbjct: 187 YASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTP 244
>sp|P97633|KC1A_RAT Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 325
Score = 393 bits (1009), Expect = e-109
Identities = 186/238 (78%), Positives = 211/238 (88%)
Frame = +3
Query: 78 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 257
+F+V K++LVRKIGSGSFGDIYL + ++NGEEVAVKLES ARHPQLLYESK+YK LQ
Sbjct: 10 EFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQG 69
Query: 258 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 437
GVGIP IRWYG YN LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E+
Sbjct: 70 GVGIPHIRWYGQG---KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEY 126
Query: 438 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 617
+H+KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTAR
Sbjct: 127 VHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTAR 186
Query: 618 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTP 791
YASINAH GIEQSRRDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK STP
Sbjct: 187 YASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTP 244
>sp|P42168|YKL1_CAEEL Putative casein kinase I C03C10.1 in chromosome III
Length = 341
Score = 392 bits (1008), Expect = e-109
Identities = 185/237 (78%), Positives = 211/237 (89%)
Frame = +3
Query: 78 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 257
DF+VA K++L+RKIGSGSFGDIY+ + V+NGEEVA+KLES ARHPQLLYESKVY+ LQ
Sbjct: 9 DFIVATKYKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQG 68
Query: 258 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 437
GVGIP IRWYG + +YN LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM+ R+E+
Sbjct: 69 GVGIPHIRWYG---TEREYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIGRIEY 125
Query: 438 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 617
+H KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D++T+ HIPYREDKNLTGTAR
Sbjct: 126 VHVKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTAR 185
Query: 618 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRST 788
YASINAH GIEQSRRDDMES+GYV MYF R TLPWQGLKA KKQKYE+I EKK +T
Sbjct: 186 YASINAHLGIEQSRRDDMESLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTT 242
>sp|Q8N752|KC1AL_HUMAN Casein kinase I, alpha-like isoform (CKI-alpha-like) (CK1)
Length = 337
Score = 376 bits (965), Expect = e-104
Identities = 176/238 (73%), Positives = 205/238 (86%)
Frame = +3
Query: 78 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 257
+ VV K++LVRKIGSGSFGD+YLG+ +NGEEVAVKLES +HPQLLYESK+Y LQ
Sbjct: 10 ELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYESKLYTILQG 69
Query: 258 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 437
GVGIP + WYG + N LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E+
Sbjct: 70 GVGIPHMHWYGQE---KDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEY 126
Query: 438 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 617
+H+KNF+HRDIKPDNFLMG GRHCNKLF++DFGL+KKY+D +T+ HIPYREDK+L GT R
Sbjct: 127 VHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVR 186
Query: 618 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTP 791
YASINAH GIEQSRRDDMES+GYVFMYF R++LPWQGLKA KKQKYE+I EKK STP
Sbjct: 187 YASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKKMSTP 244
>sp|P54367|KC1A_DROME Casein kinase I, alpha isoform (CKI-alpha) (DmCK1)
Length = 337
Score = 360 bits (925), Expect = 2e-99
Identities = 170/238 (71%), Positives = 203/238 (85%)
Frame = +3
Query: 78 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 257
+ +V K+R++RKIGSGSFGDIYLG+++ +GEEVA+K+ES +ARHPQLLYE+K+Y+ L
Sbjct: 13 EIIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSG 72
Query: 258 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 437
GVG PRIR +G + +N LVMDLLGPSLEDLFNFC R FT+KTVLML +QM+ R+E+
Sbjct: 73 GVGFPRIRHHGKE---KNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEY 129
Query: 438 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 617
IH K FIHRDIKPDNFLMGIGRHCNKLF++DFGL+KK++D T+ HI YREDKNLTGTAR
Sbjct: 130 IHLKCFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTAR 189
Query: 618 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTP 791
YASINAH GIEQSRRDDMES+GYV MYF R LPWQG+KAN K+QKYE+I EKK STP
Sbjct: 190 YASINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTP 247
>sp|P40235|HHP1_SCHPO Casein kinase I homolog hhp1
Length = 365
Score = 349 bits (896), Expect = 4e-96
Identities = 165/238 (69%), Positives = 201/238 (84%)
Frame = +3
Query: 78 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 257
D + K+R+ RKIGSGSFGDIYLG V +GEEVA+KLES A+HPQL YE +VY+ L
Sbjct: 4 DLRIGNKYRIGRKIGSGSFGDIYLGTNVVSGEEVAIKLESTRAKHPQLEYEYRVYRILSG 63
Query: 258 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 437
GVGIP +RW+G V+ YNA+VMDLLGPSLEDLFNFC R+F++KTVL+LA+Q+++R+EF
Sbjct: 64 GVGIPFVRWFG---VECDYNAMVMDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEF 120
Query: 438 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 617
IHSK+F+HRDIKPDNFLMGIG+ N++ ++DFGL+KKY+D KT HIPYRE+KNLTGTAR
Sbjct: 121 IHSKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKYRDHKTHLHIPYRENKNLTGTAR 180
Query: 618 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTP 791
YASIN H GIEQSRRDD+ES+GYV +YF R +LPWQGLKA KKQKYE+I EKK STP
Sbjct: 181 YASINTHLGIEQSRRDDLESLGYVLVYFCRGSLPWQGLKATTKKQKYEKIMEKKISTP 238
>sp|P42158|KC1D_ARATH Casein kinase I, delta isoform-like (CKI-delta)
Length = 450
Score = 346 bits (888), Expect = 4e-95
Identities = 158/234 (67%), Positives = 197/234 (84%)
Frame = +3
Query: 87 VAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQDGVG 266
V K+RL RKIGSGSFG+IYLG + EE+A+KLE+V +HPQLLYESK+Y+ LQ G G
Sbjct: 5 VGNKFRLGRKIGSGSFGEIYLGTNIHTNEELAIKLENVKTKHPQLLYESKLYRILQGGTG 64
Query: 267 IPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHS 446
+P ++W+G +G YN LVMDLLGPSLEDLFNFC R+ ++K+VLMLA+QM+ RVEF HS
Sbjct: 65 VPNVKWFGVEG---DYNVLVMDLLGPSLEDLFNFCSRKLSLKSVLMLADQMINRVEFFHS 121
Query: 447 KNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYAS 626
K+F+HRD+KPDNFLMG+GR N+++++DFGL+KKY+D+ T HIPYRE+KNLTGTARYAS
Sbjct: 122 KSFLHRDLKPDNFLMGLGRRANQVYIIDFGLAKKYRDSTTHQHIPYRENKNLTGTARYAS 181
Query: 627 INAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRST 788
+N H GIEQSRRDD+ES+GY+ MYFL+ +LPWQGLKA KKQKYERI EKK ST
Sbjct: 182 MNTHLGIEQSRRDDLESLGYILMYFLKGSLPWQGLKAGTKKQKYERISEKKVST 235
>sp|Q06486|KC1D_RAT Casein kinase I, delta isoform (CKI-delta)
sp|Q9DC28|KC1D_MOUSE Casein kinase I, delta isoform (CKI-delta) (CKId)
Length = 415
Score = 345 bits (886), Expect = 6e-95
Identities = 162/235 (68%), Positives = 197/235 (83%)
Frame = +3
Query: 87 VAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQDGVG 266
V ++RL RKIGSGSFGDIYLG ++ GEEVA+KLE V +HPQL ESK+YK +Q GVG
Sbjct: 5 VGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVG 64
Query: 267 IPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHS 446
IP IRW G +G YN +VM+LLGPSLEDLFNFC R+F++KTVL+LA+QM++R+E+IHS
Sbjct: 65 IPTIRWCGAEG---DYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
Query: 447 KNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYAS 626
KNFIHRD+KPDNFLMG+G+ N ++++DFGL+KKY+D +T HIPYRE+KNLTGTARYAS
Sbjct: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYAS 181
Query: 627 INAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTP 791
IN H GIEQSRRDD+ES+GYV MYF +LPWQGLKA K+QKYERI EKK STP
Sbjct: 182 INTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTP 236
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,304,167
Number of Sequences: 369166
Number of extensions: 1631840
Number of successful extensions: 7268
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6079
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6551
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7425705210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)