Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_O16
(259 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q96T51|RUFY1_HUMAN RUN and FYVE domain containing protei... 79 4e-15
sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (Endosome-ass... 63 2e-10
sp|Q8BL66|EEA1_MOUSE Early endosome antigen 1 63 2e-10
sp|P40343|VPS27_YEAST Vacuolar protein sorting-associated p... 56 2e-08
sp|Q9P2R3|ANFY1_HUMAN Ankyrin repeat and FYVE domain protei... 52 3e-07
sp|Q810B6|ANFY1_MOUSE Ankyrin repeat and FYVE domain protei... 52 3e-07
sp|Q22712|YW91_CAEEL Hypothetical protein T24A11.1 in chrom... 51 7e-07
sp|P34657|YOTB_CAEEL Hypothetical protein ZK632.12 in chrom... 50 2e-06
sp|Q99LI8|HGS_MOUSE Hepatocyte growth factor-regulated tyro... 50 2e-06
sp|Q9HCC9|ZFY28_HUMAN Zinc finger FYVE domain-containing pr... 50 2e-06
>sp|Q96T51|RUFY1_HUMAN RUN and FYVE domain containing protein 1 (FYVE-finger protein EIP1)
(Zinc finger FYVE domain containing protein 12)
Length = 600
Score = 78.6 bits (192), Expect = 4e-15
Identities = 31/59 (52%), Positives = 43/59 (72%)
Frame = +1
Query: 4 QCAKQFNVGRRKHLCRRCGGVFCHECSSNRMSLASSSKPMRVCDTCHNTLIKNYTSMTS 180
QC K+F++ RRKH CR CG +FC+ CSSN ++L S KP+RVCD+CH L++ +S S
Sbjct: 542 QCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSTAS 600
>sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (Endosome-associated protein p162) (Zinc
finger FYVE domain-containing protein 2)
Length = 1411
Score = 63.2 bits (152), Expect = 2e-10
Identities = 26/49 (53%), Positives = 32/49 (65%)
Frame = +1
Query: 7 CAKQFNVGRRKHLCRRCGGVFCHECSSNRMSLASSSKPMRVCDTCHNTL 153
C K F+V R+H CR+CG +FC ECS+ SS KP+RVCD C N L
Sbjct: 1361 CGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDACFNDL 1409
>sp|Q8BL66|EEA1_MOUSE Early endosome antigen 1
Length = 1411
Score = 63.2 bits (152), Expect = 2e-10
Identities = 26/51 (50%), Positives = 33/51 (64%)
Frame = +1
Query: 1 IQCAKQFNVGRRKHLCRRCGGVFCHECSSNRMSLASSSKPMRVCDTCHNTL 153
+ C K F+V R+H CR+CG +FC ECS+ SS KP+RVCD C N L
Sbjct: 1359 MSCGKCFSVTVRRHHCRQCGNIFCAECSTKNALTPSSKKPVRVCDACFNDL 1409
>sp|P40343|VPS27_YEAST Vacuolar protein sorting-associated protein VPS27
Length = 622
Score = 56.2 bits (134), Expect = 2e-08
Identities = 25/47 (53%), Positives = 33/47 (70%), Gaps = 2/47 (4%)
Frame = +1
Query: 7 CAKQFNVGRRKHLCRRCGGVFCHECSSNRMSLASSS--KPMRVCDTC 141
C+K+F++ RKH CR CGGVFC E SSN + L +P+RVCD+C
Sbjct: 179 CSKKFSLLNRKHHCRSCGGVFCQEHSSNSIPLPDLGIYEPVRVCDSC 225
>sp|Q9P2R3|ANFY1_HUMAN Ankyrin repeat and FYVE domain protein 1 (Ankyrin repeats hooked to a
zinc finger motif)
Length = 1169
Score = 52.4 bits (124), Expect = 3e-07
Identities = 21/52 (40%), Positives = 32/52 (61%), Gaps = 2/52 (3%)
Frame = +1
Query: 4 QCAKQFNVGRRKHLCRRCGGVFCHECSSNRMSLA--SSSKPMRVCDTCHNTL 153
+C +F V RKH CR CG + CH+CS+ + + +KP+RVC+ C + L
Sbjct: 1112 ECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVL 1163
>sp|Q810B6|ANFY1_MOUSE Ankyrin repeat and FYVE domain protein 1 (Ankyrin repeats hooked to a
zinc finger motif)
Length = 1169
Score = 52.4 bits (124), Expect = 3e-07
Identities = 21/52 (40%), Positives = 32/52 (61%), Gaps = 2/52 (3%)
Frame = +1
Query: 4 QCAKQFNVGRRKHLCRRCGGVFCHECSSNRMSLA--SSSKPMRVCDTCHNTL 153
+C +F V RKH CR CG + CH+CS+ + + +KP+RVC+ C + L
Sbjct: 1112 ECTAKFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVL 1163
>sp|Q22712|YW91_CAEEL Hypothetical protein T24A11.1 in chromosome III
Length = 938
Score = 51.2 bits (121), Expect = 7e-07
Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 7/79 (8%)
Frame = +1
Query: 7 CAKQFN-----VGRRKHLCRRCGGVFCHECSSNRMSLASSSKPM--RVCDTCHNTLIKNY 165
C K+FN V R+H CR CG V C +CS NR S+ K + R CD+C++++ +
Sbjct: 800 CKKEFNKLSVYVEDRQHHCRNCGRVVCEDCSKNRFSVIEEGKSVQKRACDSCYDSMHETD 859
Query: 166 TSMTSKRDSDASLR*FDTY 222
+ S+ S + + FD++
Sbjct: 860 LKL-SRATSLSEMSSFDSF 877
>sp|P34657|YOTB_CAEEL Hypothetical protein ZK632.12 in chromosome III
Length = 266
Score = 50.1 bits (118), Expect = 2e-06
Identities = 24/51 (47%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = +1
Query: 7 CAK-QFNVGRRKHLCRRCGGVFCHECSSNRMSLAS-SSKPMRVCDTCHNTL 153
C K QFN+ +R+H CR CG V C CSS + + KP+RVCD C ++L
Sbjct: 161 CGKTQFNLVQRRHHCRNCGRVVCGACSSRTFRIDNVHKKPVRVCDHCFDSL 211
>sp|Q99LI8|HGS_MOUSE Hepatocyte growth factor-regulated tyrosine kinase substrate
Length = 775
Score = 49.7 bits (117), Expect = 2e-06
Identities = 23/54 (42%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Frame = +1
Query: 4 QCAKQFNVGRRKHLCRRCGGVFCHECSSNRMSLA--SSSKPMRVCDTCHNTLIK 159
+C QF V RKH CR CG +FC +CSS ++ K +RVC+ C+ L K
Sbjct: 168 RCRVQFGVVTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNK 221
>sp|Q9HCC9|ZFY28_HUMAN Zinc finger FYVE domain-containing protein 28
Length = 887
Score = 49.7 bits (117), Expect = 2e-06
Identities = 23/48 (47%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Frame = +1
Query: 7 CAKQFNVGRRKHLCRRCGGVFCHECSSNRMSLA--SSSKPMRVCDTCH 144
C F V RRKH CR CG +FC CSS+ L KP+RVC C+
Sbjct: 826 CKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,485,705
Number of Sequences: 369166
Number of extensions: 519695
Number of successful extensions: 2520
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2066
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2484
length of database: 68,354,980
effective HSP length: 56
effective length of database: 58,009,820
effective search space used: 1682284780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)