Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_O13
(490 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O18404|HCD2_DROME 3-hydroxyacyl-CoA dehydrogenase type I... 94 2e-19
sp|O02691|HCD2_BOVIN 3-hydroxyacyl-CoA dehydrogenase type I... 93 4e-19
sp|Q99714|HCD2_HUMAN 3-hydroxyacyl-CoA dehydrogenase type I... 91 1e-18
sp|O70351|HCD2_RAT 3-hydroxyacyl-CoA dehydrogenase type II ... 90 3e-18
sp|O08756|HCD2_MOUSE 3-hydroxyacyl-CoA dehydrogenase type I... 88 9e-18
sp|P66781|YD50_MYCTU Putative oxidoreductase Rv1350/MT1393 ... 57 2e-08
sp|P17611|NODG_AZOBR Nodulation protein G 54 3e-07
sp|Q9X248|FABG_THEMA 3-oxoacyl-[acyl-carrier-protein] reduc... 53 3e-07
sp|Q9KQH7|FABG_VIBCH 3-oxoacyl-[acyl-carrier-protein] reduc... 52 7e-07
sp|P73574|FABG1_SYNY3 3-oxoacyl-[acyl-carrier-protein] redu... 52 1e-06
>sp|O18404|HCD2_DROME 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH) (Scully
protein)
Length = 255
Score = 93.6 bits (231), Expect = 2e-19
Identities = 41/62 (66%), Positives = 54/62 (87%)
Frame = +2
Query: 14 SNVPNEFDQRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIA 193
+N PN+ QRG+++NT+S+AAFDGQ GQ+AYSASKAA+ GMTLP+ARDL+ G+R+ TIA
Sbjct: 132 ANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICTIA 191
Query: 194 PG 199
PG
Sbjct: 192 PG 193
Score = 77.8 bits (190), Expect = 1e-14
Identities = 35/51 (68%), Positives = 41/51 (80%)
Frame = +1
Query: 274 PNNVQAHLSTTVPFPSRLGHPDEFAHLVQTIIENPMLNGEVIRIDGALRMM 426
P V+ L+ ++PFP RLG P E+AHLVQ I ENP+LNGEVIRIDGALRMM
Sbjct: 204 PEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLLNGEVIRIDGALRMM 254
>sp|O02691|HCD2_BOVIN 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH)
Length = 261
Score = 92.8 bits (229), Expect = 4e-19
Identities = 43/61 (70%), Positives = 53/61 (86%)
Frame = +2
Query: 17 NVPNEFDQRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAP 196
N P++ QRG++INT+S+AAF+GQ GQ+AYSASK I GMTLP+ARDLA MG+RVMTIAP
Sbjct: 139 NEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPMGIRVMTIAP 198
Query: 197 G 199
G
Sbjct: 199 G 199
Score = 72.8 bits (177), Expect = 4e-13
Identities = 34/50 (68%), Positives = 41/50 (82%)
Frame = +1
Query: 274 PNNVQAHLSTTVPFPSRLGHPDEFAHLVQTIIENPMLNGEVIRIDGALRM 423
P+ V+ L++ VPFPSRLG P E+AHLVQ IIEN LNGEVIR+DGA+RM
Sbjct: 210 PDKVRNFLASQVPFPSRLGDPAEYAHLVQAIIENSFLNGEVIRLDGAIRM 259
>sp|Q99714|HCD2_HUMAN 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH) (Endoplasmic
reticulum-associated amyloid beta-peptide binding
protein) (Short-chain type dehydrogenase/reductase
XH98G2)
Length = 261
Score = 91.3 bits (225), Expect = 1e-18
Identities = 42/61 (68%), Positives = 53/61 (86%)
Frame = +2
Query: 17 NVPNEFDQRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAP 196
N P++ QRG++INT+S+AAF+GQ GQ+AYSASK I GMTLP+ARDLA +G+RVMTIAP
Sbjct: 139 NEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAP 198
Query: 197 G 199
G
Sbjct: 199 G 199
Score = 73.9 bits (180), Expect = 2e-13
Identities = 35/50 (70%), Positives = 40/50 (80%)
Frame = +1
Query: 274 PNNVQAHLSTTVPFPSRLGHPDEFAHLVQTIIENPMLNGEVIRIDGALRM 423
P V L++ VPFPSRLG P E+AHLVQ IIENP LNGEVIR+DGA+RM
Sbjct: 210 PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVIRLDGAIRM 259
>sp|O70351|HCD2_RAT 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH) (Endoplasmic
reticulum-associated amyloid beta-peptide binding
protein)
Length = 261
Score = 89.7 bits (221), Expect = 3e-18
Identities = 41/61 (67%), Positives = 53/61 (86%)
Frame = +2
Query: 17 NVPNEFDQRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAP 196
N P++ QRG++INT+S+AAF+GQ GQ+AYSASK I GMTLP+ARDLA +G+RV+TIAP
Sbjct: 139 NEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAP 198
Query: 197 G 199
G
Sbjct: 199 G 199
Score = 75.1 bits (183), Expect = 8e-14
Identities = 34/50 (68%), Positives = 42/50 (84%)
Frame = +1
Query: 274 PNNVQAHLSTTVPFPSRLGHPDEFAHLVQTIIENPMLNGEVIRIDGALRM 423
P+ V+ L++ VPFPSRLG P E+AHLVQ +IENP LNGEVIR+DGA+RM
Sbjct: 210 PDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFLNGEVIRLDGAIRM 259
>sp|O08756|HCD2_MOUSE 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH) (Endoplasmic
reticulum-associated amyloid beta-peptide binding
protein)
Length = 261
Score = 88.2 bits (217), Expect = 9e-18
Identities = 41/61 (67%), Positives = 52/61 (85%)
Frame = +2
Query: 17 NVPNEFDQRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAP 196
N P++ QRG++INT+S+AAF+GQ GQ+AYSASK I GMTLP+ARDLA G+RV+TIAP
Sbjct: 139 NEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIDGMTLPIARDLAPTGIRVVTIAP 198
Query: 197 G 199
G
Sbjct: 199 G 199
Score = 77.4 bits (189), Expect = 2e-14
Identities = 36/50 (72%), Positives = 42/50 (84%)
Frame = +1
Query: 274 PNNVQAHLSTTVPFPSRLGHPDEFAHLVQTIIENPMLNGEVIRIDGALRM 423
P V+ L++ VPFPSRLG P E+AHLVQTIIENP LNGEVIR+DGA+RM
Sbjct: 210 PEKVRNFLASQVPFPSRLGDPAEYAHLVQTIIENPFLNGEVIRLDGAIRM 259
>sp|P66781|YD50_MYCTU Putative oxidoreductase Rv1350/MT1393
sp|P66782|YD85_MYCBO Putative oxidoreductase Mb1385
Length = 247
Score = 57.0 bits (136), Expect = 2e-08
Identities = 27/54 (50%), Positives = 38/54 (70%)
Frame = +2
Query: 38 QRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAPG 199
+RG ++N SS++ G GQ+ YSA+KA I GMT A++LA +G+RV IAPG
Sbjct: 133 KRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAPG 186
>sp|P17611|NODG_AZOBR Nodulation protein G
Length = 246
Score = 53.5 bits (127), Expect = 3e-07
Identities = 27/52 (51%), Positives = 34/52 (65%)
Frame = +2
Query: 44 GIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAPG 199
G +IN SS+ GQ+GQ+ YSA+KA + G T LA +LA GV V IAPG
Sbjct: 133 GRIINISSVNGVKGQAGQTNYSAAKAGVIGFTKALAAELATKGVTVNAIAPG 184
>sp|Q9X248|FABG_THEMA 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
protein reductase)
Length = 246
Score = 53.1 bits (126), Expect = 3e-07
Identities = 27/61 (44%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Frame = +2
Query: 20 VPNEFDQR-GIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAP 196
VP QR G ++N SS+ G GQ+ Y+ASKA + GMT A++LA +RV +AP
Sbjct: 125 VPYMIKQRNGSIVNVSSVVGIYGNPGQTNYAASKAGVIGMTKTWAKELAGRNIRVNAVAP 184
Query: 197 G 199
G
Sbjct: 185 G 185
>sp|Q9KQH7|FABG_VIBCH 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
protein reductase)
Length = 244
Score = 52.0 bits (123), Expect = 7e-07
Identities = 23/54 (42%), Positives = 37/54 (68%)
Frame = +2
Query: 38 QRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAPG 199
++G +IN S+ G +GQ+ Y+A+KA + G T +AR++A+ GV V T+APG
Sbjct: 129 RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNTVAPG 182
>sp|P73574|FABG1_SYNY3 3-oxoacyl-[acyl-carrier-protein] reductase 1 (3-ketoacyl-acyl
carrier protein reductase 1)
Length = 247
Score = 51.6 bits (122), Expect = 1e-06
Identities = 24/52 (46%), Positives = 35/52 (67%)
Frame = +2
Query: 44 GIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAPG 199
G +IN +S+A G GQ+ YSA+KA + G T +A++LA+ GV V +APG
Sbjct: 136 GRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNAVAPG 187
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,299,026
Number of Sequences: 369166
Number of extensions: 1015903
Number of successful extensions: 2942
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2876
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2939
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 2970720600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)