Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_N22
(683 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P46926|GNPI_HUMAN Glucosamine-6-phosphate isomerase (Glu... 308 7e-84
sp|Q64422|GNPI_MESAU Glucosamine-6-phosphate isomerase (Glu... 308 9e-84
sp|Q5R8T8|GNPI_PONPY Glucosamine-6-phosphate isomerase (Glu... 306 3e-83
sp|O88958|GNPI_MOUSE Glucosamine-6-phosphate isomerase (Glu... 304 2e-82
sp|Q9XVJ2|GNPI_CAEEL Probable glucosamine-6-phosphate isome... 274 2e-73
sp|O30564|NAGB_BORBU Glucosamine-6-phosphate deaminase (Glu... 261 9e-70
sp|Q8REG1|NAGB_FUSNN Glucosamine-6-phosphate deaminase (Glu... 250 2e-66
sp|Q8FJX7|NAGB_ECOL6 Glucosamine-6-phosphate deaminase (Glu... 250 3e-66
sp|P0A759|NAGB_ECOLI Glucosamine-6-phosphate deaminase (Glu... 249 5e-66
sp|P59688|NAGB_SHIFL Glucosamine-6-phosphate deaminase (Glu... 248 8e-66
>sp|P46926|GNPI_HUMAN Glucosamine-6-phosphate isomerase (Glucosamine-6-phosphate
deaminase) (GNPDA) (GlcN6P deaminase) (Oscillin)
Length = 289
Score = 308 bits (790), Expect = 7e-84
Identities = 150/207 (72%), Positives = 176/207 (85%), Gaps = 1/207 (0%)
Frame = +2
Query: 47 KEFIEYYKAGQISFKYVVTFNMDEYVDLPRNHPQSYHSFMFNNFFKHIDINPNNCYILNG 226
K+ IEYYK G +SFKYV TFNMDEYV LPR+HP+SYHSFM+NNFFKHIDI+P N +IL+G
Sbjct: 50 KKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDG 109
Query: 227 NATNLQVECEQFEKLISQHGGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLAQETIQA 406
NA +LQ EC+ FE+ I GGIELFVGGIGPDGH+AFNEPGSSLVSRTRVKTLA +TI A
Sbjct: 110 NAVDLQAECDAFEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILA 169
Query: 407 NSRFFENDLSKVPTKALTVGVGTVMEAREVLILITGSTKALALHKAIEEGVNHMWTVSAF 586
N+RFF+ +L+KVPT ALTVGVGTVM+AREV+ILITG+ KA AL+KAIEEGVNHMWTVSAF
Sbjct: 170 NARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAF 229
Query: 587 QQHPKTIFVVMR-CNLRIKNEDCQIFK 664
QQHP+T+FV L +K + + FK
Sbjct: 230 QQHPRTVFVCDEDATLELKVKTVKYFK 256
>sp|Q64422|GNPI_MESAU Glucosamine-6-phosphate isomerase (Glucosamine-6-phosphate
deaminase) (GNPDA) (GlcN6P deaminase) (Oscillin)
Length = 289
Score = 308 bits (789), Expect = 9e-84
Identities = 151/207 (72%), Positives = 175/207 (84%), Gaps = 1/207 (0%)
Frame = +2
Query: 47 KEFIEYYKAGQISFKYVVTFNMDEYVDLPRNHPQSYHSFMFNNFFKHIDINPNNCYILNG 226
++ IEYYK G +SFKYV TFNMDEYV LPR HP+SYHSFM+NNFFKHIDI+P N +IL+G
Sbjct: 50 QKLIEYYKNGDLSFKYVKTFNMDEYVGLpreHPESYHSFMWNNFFKHIDIHPENTHILDG 109
Query: 227 NATNLQVECEQFEKLISQHGGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLAQETIQA 406
NA +LQ EC+ FE+ I GGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLA +TI A
Sbjct: 110 NAADLQAECDAFEEKIRAAGGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLAMDTILA 169
Query: 407 NSRFFENDLSKVPTKALTVGVGTVMEAREVLILITGSTKALALHKAIEEGVNHMWTVSAF 586
N+RFF+ DL+KVPT ALTVGVGTVM+AREV+ILITG+ KA AL+KAIEEGVNHMWTVSAF
Sbjct: 170 NARFFDGDLAKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAF 229
Query: 587 QQHPKTIFVVMR-CNLRIKNEDCQIFK 664
QQHP+T+FV L +K + + FK
Sbjct: 230 QQHPRTVFVCDEDATLELKVKTVKYFK 256
>sp|Q5R8T8|GNPI_PONPY Glucosamine-6-phosphate isomerase (Glucosamine-6-phosphate
deaminase) (GNPDA) (GlcN6P deaminase) (Oscillin)
Length = 289
Score = 306 bits (785), Expect = 3e-83
Identities = 149/207 (71%), Positives = 175/207 (84%), Gaps = 1/207 (0%)
Frame = +2
Query: 47 KEFIEYYKAGQISFKYVVTFNMDEYVDLPRNHPQSYHSFMFNNFFKHIDINPNNCYILNG 226
K+ IEYYK G + FKYV TFNMDEYV LPR+HP+SYHSFM+NNFFKHIDI+P N +IL+G
Sbjct: 50 KKLIEYYKNGDLPFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDG 109
Query: 227 NATNLQVECEQFEKLISQHGGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLAQETIQA 406
NA +LQ EC+ FE+ I GGIELFVGGIGPDGH+AFNEPGSSLVSRTRVKTLA +TI A
Sbjct: 110 NAVDLQAECDAFEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILA 169
Query: 407 NSRFFENDLSKVPTKALTVGVGTVMEAREVLILITGSTKALALHKAIEEGVNHMWTVSAF 586
N+RFF+ +L+KVPT ALTVGVGTVM+AREV+ILITG+ KA AL+KAIEEGVNHMWTVSAF
Sbjct: 170 NARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAF 229
Query: 587 QQHPKTIFVVMR-CNLRIKNEDCQIFK 664
QQHP+T+FV L +K + + FK
Sbjct: 230 QQHPRTVFVCDEDATLELKVKTVKYFK 256
>sp|O88958|GNPI_MOUSE Glucosamine-6-phosphate isomerase (Glucosamine-6-phosphate
deaminase) (GNPDA) (GlcN6P deaminase) (Oscillin)
Length = 289
Score = 304 bits (778), Expect = 2e-82
Identities = 147/207 (71%), Positives = 176/207 (85%), Gaps = 1/207 (0%)
Frame = +2
Query: 47 KEFIEYYKAGQISFKYVVTFNMDEYVDLPRNHPQSYHSFMFNNFFKHIDINPNNCYILNG 226
++ IEYYK G +SF+YV TFNMDEYV LPR+HP+SYHSFM++NFFKHIDI+P N +IL+G
Sbjct: 50 QKLIEYYKNGDLSFQYVKTFNMDEYVGLPRDHPESYHSFMWDNFFKHIDIHPENTHILDG 109
Query: 227 NATNLQVECEQFEKLISQHGGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLAQETIQA 406
NA +LQ EC+ FE+ I GGIELFVGGIGPDGH+AFNEPGSSLVSRTRVKTLA +TI A
Sbjct: 110 NAADLQAECDAFEEKIQAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILA 169
Query: 407 NSRFFENDLSKVPTKALTVGVGTVMEAREVLILITGSTKALALHKAIEEGVNHMWTVSAF 586
N+RFF+ DL+KVPT ALTVGVGTVM+A+EV+ILITG+ KA AL+KAIEEGVNHMWTVSAF
Sbjct: 170 NARFFDGDLAKVPTMALTVGVGTVMDAKEVMILITGAHKAFALYKAIEEGVNHMWTVSAF 229
Query: 587 QQHPKTIFVVMR-CNLRIKNEDCQIFK 664
QQHP+T+FV L +K + + FK
Sbjct: 230 QQHPRTVFVCDEDATLELKVKTVKYFK 256
>sp|Q9XVJ2|GNPI_CAEEL Probable glucosamine-6-phosphate isomerase (Glucosamine-6-phosphate
deaminase) (GNPDA) (GlcN6P deaminase)
Length = 267
Score = 274 bits (700), Expect = 2e-73
Identities = 134/207 (64%), Positives = 168/207 (81%), Gaps = 1/207 (0%)
Frame = +2
Query: 47 KEFIEYYKAGQISFKYVVTFNMDEYVDLPRNHPQSYHSFMFNNFFKHIDINPNNCYILNG 226
K+ IE+Y AG ISF+ V TFNMDEYVDLPR+H +SYHSFMF+NFF+HIDINP N +IL+G
Sbjct: 49 KKLIEFYNAGVISFEKVKTFNMDEYVDLPRDHTESYHSFMFDNFFRHIDINPANIHILDG 108
Query: 227 NATNLQVECEQFEKLISQHGGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLAQETIQA 406
N ++ + ECE++E+ I + GGI+LFVGGIGPDGH+AFNEPGSSL SRTR+KTL ++TIQA
Sbjct: 109 NTSDHEKECEEYERKIKESGGIDLFVGGIGPDGHIAFNEPGSSLASRTRIKTLNEDTIQA 168
Query: 407 NSRFFENDLSKVPTKALTVGVGTVMEAREVLILITGSTKALALHKAIEEGVNHMWTVSAF 586
N+RFF D++KVPT+ALTVGV TVM+AREV+ILITGS KALALH+AIE G++HM TVSA
Sbjct: 169 NARFFGGDITKVPTQALTVGVQTVMDAREVMILITGSHKALALHQAIECGISHMCTVSAM 228
Query: 587 QQHPKTIFVVMR-CNLRIKNEDCQIFK 664
Q H F+ L +K + + FK
Sbjct: 229 QMHRCATFIADEDATLELKVKTVKYFK 255
>sp|O30564|NAGB_BORBU Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate
isomerase) (GNPDA) (GlcN6P deaminase)
Length = 268
Score = 261 bits (668), Expect = 9e-70
Identities = 124/189 (65%), Positives = 149/189 (78%)
Frame = +2
Query: 47 KEFIEYYKAGQISFKYVVTFNMDEYVDLPRNHPQSYHSFMFNNFFKHIDINPNNCYILNG 226
K IE K +ISF+ V+TFNMDEY+ + NHP+SYHSFM+NNFF HIDI N ILNG
Sbjct: 50 KNLIELNKNKKISFQNVITFNMDEYIGIEENHPESYHSFMWNNFFSHIDIKKENINILNG 109
Query: 227 NATNLQVECEQFEKLISQHGGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLAQETIQA 406
NA+NL+ ECE++EK I GGI LFVGGIGPDGH+AFNEPGSSL SRTR+KTL Q+TI A
Sbjct: 110 NASNLKKECEEYEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIKTLTQDTIIA 169
Query: 407 NSRFFENDLSKVPTKALTVGVGTVMEAREVLILITGSTKALALHKAIEEGVNHMWTVSAF 586
NSRFFE D++KVP ALTVG+GT+M+++EVLI++ G KA AL AIE+GVNHMWT+SA
Sbjct: 170 NSRFFEGDVNKVPKNALTVGIGTIMDSQEVLIIVNGHNKARALKHAIEKGVNHMWTISAL 229
Query: 587 QQHPKTIFV 613
Q H I V
Sbjct: 230 QLHKNAIIV 238
>sp|Q8REG1|NAGB_FUSNN Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate
isomerase) (GNPDA) (GlcN6P deaminase)
Length = 274
Score = 250 bits (639), Expect = 2e-66
Identities = 121/210 (57%), Positives = 151/210 (71%)
Frame = +2
Query: 47 KEFIEYYKAGQISFKYVVTFNMDEYVDLPRNHPQSYHSFMFNNFFKHIDINPNNCYILNG 226
K I++ K G ISFK V+TFNMDEYV LP+ HPQSYH +M+NNFF HIDI+ N ILNG
Sbjct: 49 KRLIQFNKEGIISFKNVITFNMDEYVGLPKTHPQSYHYYMYNNFFNHIDIDKENVNILNG 108
Query: 227 NATNLQVECEQFEKLISQHGGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLAQETIQA 406
A N + EC ++E+ I + GGI+LF+GG+G DGH+AFNEPGSS SRTR K L ++TI
Sbjct: 109 MAKNYKEECRKYEEKILEVGGIDLFLGGVGVDGHIAFNEPGSSFKSRTREKQLTEDTIIV 168
Query: 407 NSRFFENDLSKVPTKALTVGVGTVMEAREVLILITGSTKALALHKAIEEGVNHMWTVSAF 586
NSRFF ND++KVP ALTVGV T+M+A+EVLI++ G+ KA ALH IEEG+NHMWT+SA
Sbjct: 169 NSRFFNNDITKVPQSALTVGVSTIMDAKEVLIMVEGNNKARALHMGIEEGINHMWTISAL 228
Query: 587 QQHPKTIFVVMRCNLRIKNEDCQIFKVSMY 676
Q H K I V + C KV+ Y
Sbjct: 229 QLHEKAIIVA-------DEDACAELKVATY 251
>sp|Q8FJX7|NAGB_ECOL6 Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate
isomerase) (GNPDA) (GlcN6P deaminase)
Length = 266
Score = 250 bits (638), Expect = 3e-66
Identities = 116/189 (61%), Positives = 147/189 (77%)
Frame = +2
Query: 47 KEFIEYYKAGQISFKYVVTFNMDEYVDLPRNHPQSYHSFMFNNFFKHIDINPNNCYILNG 226
K +E +KAGQ+SFK+VVTFNMDEYV LP+ HP+SY+SFM NFF H+DI N +LNG
Sbjct: 50 KALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNG 109
Query: 227 NATNLQVECEQFEKLISQHGGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLAQETIQA 406
NA +++ EC Q+E+ I +G I LF+GG+G DGH+AFNEP SSL SRTR+KTL +T A
Sbjct: 110 NAPDIEAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVA 169
Query: 407 NSRFFENDLSKVPTKALTVGVGTVMEAREVLILITGSTKALALHKAIEEGVNHMWTVSAF 586
NSRFF+ND+++VP ALTVGVGT+++A EV+IL+ GS KALAL A+E VNHMWT+S
Sbjct: 170 NSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEGCVNHMWTISCL 229
Query: 587 QQHPKTIFV 613
Q HPK I V
Sbjct: 230 QLHPKAIMV 238
>sp|P0A759|NAGB_ECOLI Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate
isomerase) (GNPDA) (GlcN6P deaminase)
sp|P0A760|NAGB_ECO57 Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate
isomerase) (GNPDA) (GlcN6P deaminase)
Length = 266
Score = 249 bits (636), Expect = 5e-66
Identities = 116/189 (61%), Positives = 146/189 (77%)
Frame = +2
Query: 47 KEFIEYYKAGQISFKYVVTFNMDEYVDLPRNHPQSYHSFMFNNFFKHIDINPNNCYILNG 226
K +E +KAGQ+SFK+VVTFNMDEYV LP+ HP+SY+SFM NFF H+DI N +LNG
Sbjct: 50 KALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNG 109
Query: 227 NATNLQVECEQFEKLISQHGGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLAQETIQA 406
NA ++ EC Q+E+ I +G I LF+GG+G DGH+AFNEP SSL SRTR+KTL +T A
Sbjct: 110 NAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVA 169
Query: 407 NSRFFENDLSKVPTKALTVGVGTVMEAREVLILITGSTKALALHKAIEEGVNHMWTVSAF 586
NSRFF+ND+++VP ALTVGVGT+++A EV+IL+ GS KALAL A+E VNHMWT+S
Sbjct: 170 NSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEGCVNHMWTISCL 229
Query: 587 QQHPKTIFV 613
Q HPK I V
Sbjct: 230 QLHPKAIMV 238
>sp|P59688|NAGB_SHIFL Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate
isomerase) (GNPDA) (GlcN6P deaminase)
Length = 266
Score = 248 bits (634), Expect = 8e-66
Identities = 115/189 (60%), Positives = 146/189 (77%)
Frame = +2
Query: 47 KEFIEYYKAGQISFKYVVTFNMDEYVDLPRNHPQSYHSFMFNNFFKHIDINPNNCYILNG 226
K +E +KAGQ+SFK+VVTFNMDEYV LP+ HP+SY+SFM NFF H+DI N +LNG
Sbjct: 50 KALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNG 109
Query: 227 NATNLQVECEQFEKLISQHGGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLAQETIQA 406
NA ++ EC Q+E+ I +G I LF+GG+G DGH+AFNEP SSL SRTR+KTL +T A
Sbjct: 110 NAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVA 169
Query: 407 NSRFFENDLSKVPTKALTVGVGTVMEAREVLILITGSTKALALHKAIEEGVNHMWTVSAF 586
NSRFF+ND+++VP ALTVGVGT+++A EV+I++ GS KALAL A+E VNHMWT+S
Sbjct: 170 NSRFFDNDVNQVPKYALTVGVGTLLDAEEVMIMVLGSQKALALQAAVEGCVNHMWTISCL 229
Query: 587 QQHPKTIFV 613
Q HPK I V
Sbjct: 230 QLHPKAIMV 238
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,525,928
Number of Sequences: 369166
Number of extensions: 1434573
Number of successful extensions: 4281
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4043
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4230
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5830600200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)