Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_M05
(652 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P55809|SCOT_HUMAN Succinyl-CoA:3-ketoacid-coenzyme A tra... 122 6e-28
sp|Q29551|SCOT_PIG Succinyl-CoA:3-ketoacid-coenzyme A trans... 121 2e-27
sp|Q9D0K2|SCOT_MOUSE Succinyl-CoA:3-ketoacid-coenzyme A tra... 120 2e-27
sp|P63651|SCOB_MYCBO Probable succinyl-CoA:3-ketoacid-coenz... 117 2e-26
sp|Q9BYC2|SCOT2_HUMAN Succinyl-CoA:3-ketoacid-coenzyme A tr... 114 3e-25
sp|O34263|SCOB_XANCP Succinyl-CoA:3-ketoacid-coenzyme A tra... 112 1e-24
sp|P56007|SCOB_HELPY Succinyl-CoA:3-ketoacid-coenzyme A tra... 112 1e-24
sp|P42316|SCOB_BACSU Probable succinyl-CoA:3-ketoacid-coenz... 111 1e-24
sp|Q9ZLE4|SCOB_HELPJ Succinyl-CoA:3-ketoacid-coenzyme A tra... 111 2e-24
sp|Q09450|SCOT_CAEEL Probable succinyl-CoA:3-ketoacid-coenz... 108 2e-23
>sp|P55809|SCOT_HUMAN Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial
precursor (Somatic-type succinyl CoA:3-oxoacid
CoA-transferase) (Scot-S)
Length = 520
Score = 122 bits (307), Expect = 6e-28
Identities = 55/102 (53%), Positives = 78/102 (76%)
Frame = +2
Query: 248 GKMIKGMGGAMDLVSTSGTKVIIATEHCASDGSPKIVNQCSLPLTGVQCVNTIVTEKCVF 427
GKM+KGMGGAMDLVS++ TKV++ EH A + KI+ +C+LPLTG QCVN I+TEK VF
Sbjct: 417 GKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVF 476
Query: 428 EVKPDVGLVLTEIAEGIDIQEIVETTGCEFQLAEKVLPMQQI 553
+V GL L E+ EG+ + ++ ++TGC+F ++ K++PMQQI
Sbjct: 477 DVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQI 518
Score = 114 bits (284), Expect = 3e-25
Identities = 53/82 (64%), Positives = 65/82 (79%)
Frame = +3
Query: 3 AIELKSGMYVNLGIGMPTQLPQHIPKDLNVTLQSENGILGIGPYPLENQVDADLINAGKE 182
A+E + GMY NLGIG+P I ++ V LQSENG+LG+GPYP +++ DADLINAGKE
Sbjct: 310 ALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEADADLINAGKE 369
Query: 183 TVTLLPGGSYFSSDNSFAMIRG 248
TVT+LPG S+FSSD SFAMIRG
Sbjct: 370 TVTILPGASFFSSDESFAMIRG 391
>sp|Q29551|SCOT_PIG Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial
precursor (Somatic-type succinyl CoA:3-oxoacid
CoA-transferase) (Scot-S)
Length = 520
Score = 121 bits (303), Expect = 2e-27
Identities = 58/82 (70%), Positives = 67/82 (81%)
Frame = +3
Query: 3 AIELKSGMYVNLGIGMPTQLPQHIPKDLNVTLQSENGILGIGPYPLENQVDADLINAGKE 182
A+E + GMY NLGIG+P I ++ V LQSENGILG+GPYPL+N+VDADLINAGKE
Sbjct: 310 ALEFEDGMYANLGIGIPLLASNFISPNMTVHLQSENGILGLGPYPLQNEVDADLINAGKE 369
Query: 183 TVTLLPGGSYFSSDNSFAMIRG 248
TVT+LPG SYFSSD SFAMIRG
Sbjct: 370 TVTVLPGASYFSSDESFAMIRG 391
Score = 121 bits (303), Expect = 2e-27
Identities = 54/102 (52%), Positives = 78/102 (76%)
Frame = +2
Query: 248 GKMIKGMGGAMDLVSTSGTKVIIATEHCASDGSPKIVNQCSLPLTGVQCVNTIVTEKCVF 427
GK++KGMGGAMDLVS++ TKV++ EH A + KI+ +C+LPLTG QCVN I+TEK VF
Sbjct: 417 GKLVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVF 476
Query: 428 EVKPDVGLVLTEIAEGIDIQEIVETTGCEFQLAEKVLPMQQI 553
+V GL L E+ EG+ + +I ++TGC+F ++ K++PMQQ+
Sbjct: 477 DVDRKKGLTLIELWEGLTVDDIKKSTGCDFAVSPKLIPMQQV 518
>sp|Q9D0K2|SCOT_MOUSE Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial
precursor (Somatic-type succinyl CoA:3-oxoacid
CoA-transferase) (Scot-S)
Length = 520
Score = 120 bits (302), Expect = 2e-27
Identities = 56/102 (54%), Positives = 77/102 (75%)
Frame = +2
Query: 248 GKMIKGMGGAMDLVSTSGTKVIIATEHCASDGSPKIVNQCSLPLTGVQCVNTIVTEKCVF 427
GKM+KGMGGAMDLVS+S TKV++ EH A + KI+ +C+LPLTG QCVN I+TEK VF
Sbjct: 417 GKMVKGMGGAMDLVSSSKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKGVF 476
Query: 428 EVKPDVGLVLTEIAEGIDIQEIVETTGCEFQLAEKVLPMQQI 553
+V GL L E+ EG+ + +I ++TGC+F ++ ++PMQQI
Sbjct: 477 DVDKKNGLTLIELWEGLTVDDIKKSTGCDFAVSPNLMPMQQI 518
Score = 115 bits (288), Expect = 1e-25
Identities = 54/82 (65%), Positives = 66/82 (80%)
Frame = +3
Query: 3 AIELKSGMYVNLGIGMPTQLPQHIPKDLNVTLQSENGILGIGPYPLENQVDADLINAGKE 182
A+E + GMY NLGIG+P I ++ V LQSENG+LG+GPYPL+++ DADLINAGKE
Sbjct: 310 ALEFEDGMYANLGIGIPLLASNFISPNMTVHLQSENGVLGLGPYPLKDEADADLINAGKE 369
Query: 183 TVTLLPGGSYFSSDNSFAMIRG 248
TVT+LPG S+FSSD SFAMIRG
Sbjct: 370 TVTVLPGASFFSSDESFAMIRG 391
>sp|P63651|SCOB_MYCBO Probable succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B
(Succinyl CoA:3-oxoacid CoA-transferase) (OXCT B)
sp|P63650|SCOB_MYCTU Probable succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B
(Succinyl CoA:3-oxoacid CoA-transferase) (OXCT B)
Length = 218
Score = 117 bits (294), Expect = 2e-26
Identities = 55/82 (67%), Positives = 63/82 (76%)
Frame = +3
Query: 3 AIELKSGMYVNLGIGMPTQLPQHIPKDLNVTLQSENGILGIGPYPLENQVDADLINAGKE 182
A E + G YVNLGIGMPT +P HIP ++V L SENGILG+GPYP VDADLINAGKE
Sbjct: 16 AAEFEDGQYVNLGIGMPTLIPNHIPDGVHVVLHSENGILGVGPYPRREDVDADLINAGKE 75
Query: 183 TVTLLPGGSYFSSDNSFAMIRG 248
TVT LPG ++FSS SF +IRG
Sbjct: 76 TVTTLPGAAFFSSSTSFGIIRG 97
Score = 92.8 bits (229), Expect = 7e-19
Identities = 49/86 (56%), Positives = 60/86 (69%)
Frame = +2
Query: 248 GKMIKGMGGAMDLVSTSGTKVIIATEHCASDGSPKIVNQCSLPLTGVQCVNTIVTEKCVF 427
GKM+KGMGGAMDLV KVI+ EH A DGSPKI+ +C+LPLTGV CV+ IVTE V
Sbjct: 123 GKMVKGMGGAMDLVH-GARKVIVMMEHTAKDGSPKILERCTLPLTGVGCVDRIVTELAVI 181
Query: 428 EVKPDVGLVLTEIAEGIDIQEIVETT 505
+V D GL L + A G+ + E+V T
Sbjct: 182 DVCAD-GLHLVQTAPGVSVDEVVAKT 206
>sp|Q9BYC2|SCOT2_HUMAN Succinyl-CoA:3-ketoacid-coenzyme A transferase 2, mitochondrial
precursor (Testis-specific succinyl CoA:3-oxoacid
CoA-transferase) (SCOT-t)
Length = 517
Score = 114 bits (284), Expect = 3e-25
Identities = 49/102 (48%), Positives = 74/102 (72%)
Frame = +2
Query: 248 GKMIKGMGGAMDLVSTSGTKVIIATEHCASDGSPKIVNQCSLPLTGVQCVNTIVTEKCVF 427
GK +KGMGGAMDLVS+ T+V++ +HC D +PKI+ +C++PLTG +CV+ I+TEK VF
Sbjct: 414 GKKVKGMGGAMDLVSSQKTRVVVTMQHCTKDNTPKIMEKCTMPLTGKRCVDRIITEKAVF 473
Query: 428 EVKPDVGLVLTEIAEGIDIQEIVETTGCEFQLAEKVLPMQQI 553
+V L L E+ EG+ + +I ++TGC F ++ + PMQQ+
Sbjct: 474 DVHRKKELTLRELWEGLTVDDIKKSTGCAFAVSPNLRPMQQV 515
Score = 111 bits (278), Expect = 1e-24
Identities = 52/82 (63%), Positives = 65/82 (79%)
Frame = +3
Query: 3 AIELKSGMYVNLGIGMPTQLPQHIPKDLNVTLQSENGILGIGPYPLENQVDADLINAGKE 182
A+E + GMY NLGIG+P I + V L SENGILG+GP+P E++VDADLINAGK+
Sbjct: 307 ALEFEDGMYANLGIGIPLLASNFISPSMTVHLHSENGILGLGPFPTEDEVDADLINAGKQ 366
Query: 183 TVTLLPGGSYFSSDNSFAMIRG 248
TVT+LPGG +F+SD+SFAMIRG
Sbjct: 367 TVTVLPGGCFFASDDSFAMIRG 388
>sp|O34263|SCOB_XANCP Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (Succinyl
CoA:3-oxoacid CoA-transferase) (OXCT B)
Length = 213
Score = 112 bits (279), Expect = 1e-24
Identities = 55/82 (67%), Positives = 65/82 (79%)
Frame = +3
Query: 3 AIELKSGMYVNLGIGMPTQLPQHIPKDLNVTLQSENGILGIGPYPLENQVDADLINAGKE 182
A EL G YVNLGIG+PT + HIP ++V LQSENG+LGIGP+P E++VDADLINAGK+
Sbjct: 13 ARELTDGAYVNLGIGLPTLVANHIPDGVDVWLQSENGLLGIGPFPGEDEVDADLINAGKQ 72
Query: 183 TVTLLPGGSYFSSDNSFAMIRG 248
TVT G SYF S +SFAMIRG
Sbjct: 73 TVTARSGASYFGSHDSFAMIRG 94
Score = 90.5 bits (223), Expect = 3e-18
Identities = 50/91 (54%), Positives = 64/91 (70%), Gaps = 1/91 (1%)
Frame = +2
Query: 248 GKMIKGMGGAMDLVSTSGTK-VIIATEHCASDGSPKIVNQCSLPLTGVQCVNTIVTEKCV 424
GKM+KGMGGAMDLV+ G K V++ EH A DG+ KI+ QC LPLTGV V+ I+T+ V
Sbjct: 120 GKMVKGMGGAMDLVA--GVKRVVVLMEHVAKDGTHKILPQCDLPLTGVGVVDRIITDLAV 177
Query: 425 FEVKPDVGLVLTEIAEGIDIQEIVETTGCEF 517
F+V D GLVL E AEG+ ++E+ TG F
Sbjct: 178 FDV-TDGGLVLVEAAEGVGLEELRAKTGVAF 207
>sp|P56007|SCOB_HELPY Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (Succinyl
CoA:3-oxoacid CoA-transferase) (OXCT B)
Length = 207
Score = 112 bits (279), Expect = 1e-24
Identities = 54/82 (65%), Positives = 66/82 (80%)
Frame = +3
Query: 3 AIELKSGMYVNLGIGMPTQLPQHIPKDLNVTLQSENGILGIGPYPLENQVDADLINAGKE 182
A ELK GMYVNLGIG+PT + + +N+ QSENG+LGIG YPLE VDADLINAGKE
Sbjct: 10 AKELKEGMYVNLGIGLPTLVANEV-SGMNIVFQSENGLLGIGAYPLEGSVDADLINAGKE 68
Query: 183 TVTLLPGGSYFSSDNSFAMIRG 248
T+T++PG S+F+S +SFAMIRG
Sbjct: 69 TITVVPGASFFNSADSFAMIRG 90
Score = 78.2 bits (191), Expect = 2e-14
Identities = 40/91 (43%), Positives = 57/91 (62%)
Frame = +2
Query: 251 KMIKGMGGAMDLVSTSGTKVIIATEHCASDGSPKIVNQCSLPLTGVQCVNTIVTEKCVFE 430
K+IKGMGGAMDLV KVI+ EHC G K+ +CSLPLTG V+ ++T+ VFE
Sbjct: 117 KLIKGMGGAMDLVH-GAKKVIVIMEHCNKYGESKVKKECSLPLTGKGVVHQLITDLAVFE 175
Query: 431 VKPDVGLVLTEIAEGIDIQEIVETTGCEFQL 523
+ + L E+ EG+ + ++ E T EF++
Sbjct: 176 FSNN-AMKLVELQEGVSLDQVKEKTEAEFEV 205
>sp|P42316|SCOB_BACSU Probable succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B
(Succinyl CoA:3-oxoacid CoA-transferase) (OXCT B)
Length = 216
Score = 111 bits (278), Expect = 1e-24
Identities = 55/80 (68%), Positives = 62/80 (77%)
Frame = +3
Query: 9 ELKSGMYVNLGIGMPTQLPQHIPKDLNVTLQSENGILGIGPYPLENQVDADLINAGKETV 188
E+K GM VNLGIGMPT + IP ++V LQSENG+LGIGPYPLE DADLINAGKET+
Sbjct: 15 EIKDGMNVNLGIGMPTLVANEIPDGVHVMLQSENGLLGIGPYPLEGTEDADLINAGKETI 74
Query: 189 TLLPGGSYFSSDNSFAMIRG 248
T + G SYF S SFAMIRG
Sbjct: 75 TEVTGASYFDSAESFAMIRG 94
Score = 80.1 bits (196), Expect = 5e-15
Identities = 39/97 (40%), Positives = 63/97 (64%)
Frame = +2
Query: 248 GKMIKGMGGAMDLVSTSGTKVIIATEHCASDGSPKIVNQCSLPLTGVQCVNTIVTEKCVF 427
GKM+KGMGGAMDLV+ ++++ EH G K+ CSLPLTG + V+ ++T+ VF
Sbjct: 120 GKMVKGMGGAMDLVN-GAKRIVVIMEHVNKHGESKVKKTCSLPLTGQKVVHRLITDLAVF 178
Query: 428 EVKPDVGLVLTEIAEGIDIQEIVETTGCEFQLAEKVL 538
+ + + LTE+ +G+ I+E+ E T +F +++ VL
Sbjct: 179 DF-VNGRMTLTELQDGVTIEEVYEKTEADFAVSQSVL 214
>sp|Q9ZLE4|SCOB_HELPJ Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (Succinyl
CoA:3-oxoacid CoA-transferase) (OXCT B)
Length = 207
Score = 111 bits (277), Expect = 2e-24
Identities = 54/82 (65%), Positives = 66/82 (80%)
Frame = +3
Query: 3 AIELKSGMYVNLGIGMPTQLPQHIPKDLNVTLQSENGILGIGPYPLENQVDADLINAGKE 182
A ELK GMYVNLGIG+PT + + +N+ QSENG+LGIG YPLE VDADLINAGKE
Sbjct: 10 AKELKEGMYVNLGIGLPTLVANEV-SGMNIVFQSENGLLGIGAYPLEGGVDADLINAGKE 68
Query: 183 TVTLLPGGSYFSSDNSFAMIRG 248
T+T++PG S+F+S +SFAMIRG
Sbjct: 69 TITVVPGASFFNSADSFAMIRG 90
Score = 78.2 bits (191), Expect = 2e-14
Identities = 40/91 (43%), Positives = 57/91 (62%)
Frame = +2
Query: 251 KMIKGMGGAMDLVSTSGTKVIIATEHCASDGSPKIVNQCSLPLTGVQCVNTIVTEKCVFE 430
K+IKGMGGAMDLV KVI+ EHC G K+ +CSLPLTG V+ ++T+ VFE
Sbjct: 117 KLIKGMGGAMDLVH-GAKKVIVIMEHCNKYGESKVKKECSLPLTGKGVVHQLITDLAVFE 175
Query: 431 VKPDVGLVLTEIAEGIDIQEIVETTGCEFQL 523
+ + L E+ EG+ + ++ E T EF++
Sbjct: 176 FSNN-AMELVELQEGVSLDQVKEKTEAEFEV 205
>sp|Q09450|SCOT_CAEEL Probable succinyl-CoA:3-ketoacid-coenzyme A transferase,
mitochondrial precursor (3-oxoacid CoA-transferase)
Length = 521
Score = 108 bits (269), Expect = 2e-23
Identities = 52/82 (63%), Positives = 59/82 (71%)
Frame = +3
Query: 3 AIELKSGMYVNLGIGMPTQLPQHIPKDLNVTLQSENGILGIGPYPLENQVDADLINAGKE 182
A+E GMY NLGIG+PT P +IP V LQSENGI+G+GPYP + DADLINAGKE
Sbjct: 308 ALEFTDGMYANLGIGIPTLAPNYIPNGFTVHLQSENGIIGVGPYPRKGTEDADLINAGKE 367
Query: 183 TVTLLPGGSYFSSDNSFAMIRG 248
+TLL G S SD SFAMIRG
Sbjct: 368 PITLLKGASIVGSDESFAMIRG 389
Score = 105 bits (262), Expect = 1e-22
Identities = 47/105 (44%), Positives = 70/105 (66%)
Frame = +2
Query: 248 GKMIKGMGGAMDLVSTSGTKVIIATEHCASDGSPKIVNQCSLPLTGVQCVNTIVTEKCVF 427
GK++KGMGGAMDLVS G +VI+ EH + +G PKI+ C LPLTG ++ I+T+ VF
Sbjct: 415 GKLVKGMGGAMDLVSAPGARVIVVMEHVSKNGEPKILEHCELPLTGKGVISRIITDMAVF 474
Query: 428 EVKPDVGLVLTEIAEGIDIQEIVETTGCEFQLAEKVLPMQQIDLN 562
+V GL L E+ + + + +I + T C+F+++E + PM Q LN
Sbjct: 475 DVDTKNGLTLIEVRKDLTVDDIKKLTACKFEISENLKPMGQAPLN 519
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,698,339
Number of Sequences: 369166
Number of extensions: 1472929
Number of successful extensions: 3491
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3383
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3474
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5365037700
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)