Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_L16
(792 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9D964|GATM_MOUSE Glycine amidinotransferase, mitochondr... 219 5e-57
sp|P50442|GATM_RAT Glycine amidinotransferase, mitochondria... 219 7e-57
sp|P50441|GATM_PIG Glycine amidinotransferase (L-arginine:g... 219 9e-57
sp|P50440|GATM_HUMAN Glycine amidinotransferase, mitochondr... 217 3e-56
sp|P29780|STRB2_STRGR Putative inosamine-phosphate amidinot... 108 1e-23
sp|Q54258|STRB1_STRGA Inosamine-phosphate amidinotransferas... 106 6e-23
sp|P08078|STRB1_STRGR Inosamine-phosphate amidinotransferas... 101 3e-21
sp|Q54264|STRB2_STRGA Putative inosamine-phosphate amidinot... 65 2e-10
sp|P56079|CDSA_DROME Phosphatidate cytidylyltransferase, ph... 34 0.52
sp|Q9UQ07|MOK_HUMAN MAPK/MAK/MRK overlapping kinase (MOK pr... 31 3.4
>sp|Q9D964|GATM_MOUSE Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 219 bits (559), Expect = 5e-57
Identities = 112/227 (49%), Positives = 149/227 (65%), Gaps = 7/227 (3%)
Frame = +3
Query: 129 PVWAWNEWDPLEEVVVGVPDNATLPYPSQEVAATFGPPRLPFFEKHGGKKFSEVMGPEMW 308
PV ++NEWDPLEEV+VG +NA +P + EV A PF++K+GG F + +
Sbjct: 65 PVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQKNGGLYFPK----DHL 120
Query: 309 KKIEDEIXXXXXXXXXXXXXXXQPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEII 488
KK E+ +P+ ID+ ++ TP F STGLY+AMPRD ++VVG+EII
Sbjct: 121 KKAVAEVEEMCNILSMEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEII 180
Query: 489 ESPMAWRCRYFEYEAYRPLIRKYFNEGARWTSAPKCTMEEGLYDMKFDVS--QDKPYV-- 656
E+PMAWR R+FEY AYR +I+ YF+ GA+WT+APK TM + LYD + + +D+ +
Sbjct: 181 EAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDQNYPIHSVEDRHKLAA 240
Query: 657 ---YVTTELEPCFDAADFTRVGRDIFGQRSHVTNKKAIQWLRRHLAP 788
+VTTE EPCFDAADF R GRDIF QRS VTN I+W+RRHLAP
Sbjct: 241 QGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAP 287
>sp|P50442|GATM_RAT Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 219 bits (558), Expect = 7e-57
Identities = 112/227 (49%), Positives = 149/227 (65%), Gaps = 7/227 (3%)
Frame = +3
Query: 129 PVWAWNEWDPLEEVVVGVPDNATLPYPSQEVAATFGPPRLPFFEKHGGKKFSEVMGPEMW 308
PV ++NEWDPLEEV+VG +NA +P + EV A PF++K+GG F + +
Sbjct: 65 PVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQKNGGLYFPK----DHL 120
Query: 309 KKIEDEIXXXXXXXXXXXXXXXQPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEII 488
KK E+ +P+ ID+ ++ TP F STGLY+AMPRD ++VVG+EII
Sbjct: 121 KKAVAEVEEMCNILSMEGVTVKRPDPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEII 180
Query: 489 ESPMAWRCRYFEYEAYRPLIRKYFNEGARWTSAPKCTMEEGLYDMKFDVS--QDKPYV-- 656
E+PMAWR R+FEY AYR +I+ YF+ GA+WT+APK TM + LYD + + +D+ +
Sbjct: 181 EAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDQDYPIHSVEDRHKLAA 240
Query: 657 ---YVTTELEPCFDAADFTRVGRDIFGQRSHVTNKKAIQWLRRHLAP 788
+VTTE EPCFDAADF R GRDIF QRS VTN I+W+RRHLAP
Sbjct: 241 QGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAP 287
>sp|P50441|GATM_PIG Glycine amidinotransferase (L-arginine:glycine amidinotransferase)
(Transamidinase) (AT)
Length = 386
Score = 219 bits (557), Expect = 9e-57
Identities = 112/227 (49%), Positives = 147/227 (64%), Gaps = 7/227 (3%)
Frame = +3
Query: 129 PVWAWNEWDPLEEVVVGVPDNATLPYPSQEVAATFGPPRLPFFEKHGGKKFSEVMGPEMW 308
PV ++NEWDPLEEV+VG +NA +P + EV A PF++K+GG F + +
Sbjct: 28 PVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQKYGGHYFPK----DHL 83
Query: 309 KKIEDEIXXXXXXXXXXXXXXXQPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEII 488
KK EI +P+ ID+ ++ TP F STGLY AMPRD ++VVG+EII
Sbjct: 84 KKAVAEIEEMCNILKMEGVTVRRPDPIDWSVKYKTPDFESTGLYGAMPRDILIVVGNEII 143
Query: 489 ESPMAWRCRYFEYEAYRPLIRKYFNEGARWTSAPKCTMEEGLYDMKFDV--SQDKPYV-- 656
E+PMAWR R+FEY AYR +I+ YF GA+WT+APK TM + LYD + + +D+ +
Sbjct: 144 EAPMAWRARFFEYRAYRSIIKDYFRRGAKWTTAPKPTMADELYDQDYPIYSVEDRHKLAA 203
Query: 657 ---YVTTELEPCFDAADFTRVGRDIFGQRSHVTNKKAIQWLRRHLAP 788
+VTTE EPCFDAADF R GRDIF QRS VTN I+W+R+HLAP
Sbjct: 204 QGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYMGIEWMRKHLAP 250
>sp|P50440|GATM_HUMAN Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 217 bits (553), Expect = 3e-56
Identities = 112/227 (49%), Positives = 148/227 (65%), Gaps = 7/227 (3%)
Frame = +3
Query: 129 PVWAWNEWDPLEEVVVGVPDNATLPYPSQEVAATFGPPRLPFFEKHGGKKFSEVMGPEMW 308
PV ++NEWDPLEEV+VG +NA +P + EV A PF++K GG F + +
Sbjct: 65 PVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPK----DHL 120
Query: 309 KKIEDEIXXXXXXXXXXXXXXXQPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEII 488
KK EI +P+ ID+ ++ TP F STGLY+AMPRD ++VVG+EII
Sbjct: 121 KKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEII 180
Query: 489 ESPMAWRCRYFEYEAYRPLIRKYFNEGARWTSAPKCTMEEGLYDMKFDVS--QDKPYV-- 656
E+PMAWR R+FEY AYR +I+ YF+ GA+WT+APK TM + LY+ + + +D+ +
Sbjct: 181 EAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAA 240
Query: 657 ---YVTTELEPCFDAADFTRVGRDIFGQRSHVTNKKAIQWLRRHLAP 788
+VTTE EPCFDAADF R GRDIF QRS VTN I+W+RRHLAP
Sbjct: 241 QGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAP 287
>sp|P29780|STRB2_STRGR Putative inosamine-phosphate amidinotransferase II (Aminocyclitol
amidinotransferase) (ADT)
Length = 349
Score = 108 bits (271), Expect = 1e-23
Identities = 80/223 (35%), Positives = 107/223 (47%), Gaps = 4/223 (1%)
Frame = +3
Query: 126 SPVWAWNEWDPLEEVVVGVPDNATLPYPSQEVAATFGPPRLPFFEKHGGKKFSEV-MGP- 299
S V NEWDPLEEVVVG P + + A + + E G ++ EV GP
Sbjct: 2 SLVGVHNEWDPLEEVVVGTARRPCAG-PDRSLLA------VEYAEYAGPGRWQEVPTGPY 54
Query: 300 --EMWKKIEDEIXXXXXXXXXXXXXXXQPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVV 473
K+ EDE+ +P A D TP + S G PRD +LVV
Sbjct: 55 PDRALKETEDELEELCEELRGLGVTVRRPGARDSAAPVRTPDWESDGYGDLCPRDGLLVV 114
Query: 474 GDEIIESPMAWRCRYFEYEAYRPLIRKYFNEGARWTSAPKCTMEEGLYDMKFDVSQDKPY 653
GD +IE+PMA R R+ E AY+ L+ +Y G+RW SAPK + EG+Y S P
Sbjct: 115 GDTVIEAPMALRARFLESLAYKELLVEYLAAGSRWISAPKPRLAEGMY------SPSGPS 168
Query: 654 VYVTTELEPCFDAADFTRVGRDIFGQRSHVTNKKAIQWLRRHL 782
+LEP FDAA+ R+G D+ S N+ +WL+ L
Sbjct: 169 GERLRDLEPVFDAANVLRLGTDLLYLVSDSGNELGARWLQSAL 211
>sp|Q54258|STRB1_STRGA Inosamine-phosphate amidinotransferase I (Aminocyclitol
amidinotransferase) (ADT)
Length = 348
Score = 106 bits (265), Expect = 6e-23
Identities = 69/216 (31%), Positives = 104/216 (48%), Gaps = 3/216 (1%)
Frame = +3
Query: 144 NEWDPLEEVVVGVPDNATLPYPSQEVAATFGPPRLPFFEKHGGKKFSEVMGP---EMWKK 314
NEWDPLEE++VG A +P + V A + + +++ + GP + K+
Sbjct: 8 NEWDPLEEIIVGTAVGARVPRADRSVFA------VEYADEYDSQD-QVPAGPYPDRVLKE 60
Query: 315 IEDEIXXXXXXXXXXXXXXXQPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEIIES 494
E+E+ +P D TP + + G + PRD +L VG +IES
Sbjct: 61 TEEELHVLSEELTKLGVTVRRPGQRDNSALVATPDWQTDGFHDYCPRDGLLAVGQTVIES 120
Query: 495 PMAWRCRYFEYEAYRPLIRKYFNEGARWTSAPKCTMEEGLYDMKFDVSQDKPYVYVTTEL 674
PMA R R+ E AY+ ++ +YF GARW SAPK + + +Y+ Q T+L
Sbjct: 121 PMALRARFLESLAYKDILLEYFASGARWLSAPKPRLADEMYEPTAPAGQR------LTDL 174
Query: 675 EPCFDAADFTRVGRDIFGQRSHVTNKKAIQWLRRHL 782
EP FDAA+ R G D+ S N+ +WL+ L
Sbjct: 175 EPVFDAANVLRFGTDLLYLVSDSGNELGAKWLQSAL 210
>sp|P08078|STRB1_STRGR Inosamine-phosphate amidinotransferase I (Aminocyclitol
amidinotransferase) (ADT)
Length = 347
Score = 101 bits (251), Expect = 3e-21
Identities = 69/216 (31%), Positives = 100/216 (46%), Gaps = 6/216 (2%)
Frame = +3
Query: 144 NEWDPLEEVVVGVPDNATLPYPSQEVAATFGPPRLPFFEKHGGKKFSEVMGPE------M 305
NEWDPLEEV+VG A +P + V A ++ G S+ P +
Sbjct: 8 NEWDPLEEVIVGTAVGARVPTADRSVFAV----------EYAGDYESQEQIPSGAYPDRV 57
Query: 306 WKKIEDEIXXXXXXXXXXXXXXXQPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEI 485
K+ E+E+ +P D+ TP + + G + PRD +L VG I
Sbjct: 58 LKETEEELHVLAAELTKLGVTVRRPGPRDHSALIKTPDWETDGFHDYCPRDGLLSVGQTI 117
Query: 486 IESPMAWRCRYFEYEAYRPLIRKYFNEGARWTSAPKCTMEEGLYDMKFDVSQDKPYVYVT 665
IE+PMA R R+ E AY+ L+ +YF G+RW SAPK + + Y + P
Sbjct: 118 IETPMALRSRFLESLAYKDLLLEYFASGSRWLSAPKPRLTDDSY------APQAPAGERL 171
Query: 666 TELEPCFDAADFTRVGRDIFGQRSHVTNKKAIQWLR 773
T+ EP FDAA+ R G D+ S N+ +WL+
Sbjct: 172 TDEEPVFDAANVLRFGTDLLYLVSDSGNELGAKWLQ 207
>sp|Q54264|STRB2_STRGA Putative inosamine-phosphate amidinotransferase II (Aminocyclitol
amidinotransferase) (ADT)
Length = 319
Score = 65.5 bits (158), Expect = 2e-10
Identities = 57/219 (26%), Positives = 81/219 (36%), Gaps = 2/219 (0%)
Frame = +3
Query: 141 WNEWDPLEEVVVGVPDNATLPYPSQEVAATFGPPRLPFFEKHGGKKFSEVMGPE--MWKK 314
+ EWDPLEE+VVG +G E M ++
Sbjct: 7 YTEWDPLEEIVVGT-----------------------------------AVGSENRMVRE 31
Query: 315 IEDEIXXXXXXXXXXXXXXXQPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEIIES 494
EDE+ + D P + A PRD +L VG+ +I++
Sbjct: 32 TEDELDGLCEELRGLGVTVRRLPPQDPASPPAPPDRGADTALAYRPRDGLLTVGETVIQT 91
Query: 495 PMAWRCRYFEYEAYRPLIRKYFNEGARWTSAPKCTMEEGLYDMKFDVSQDKPYVYVTTEL 674
P + A R L+ +YF G+RW SAP + + +YD P EL
Sbjct: 92 PAVPGLPSLQSPACRMLLMEYFTSGSRWISAPPPVLTDVMYD------PTAPAGERLREL 145
Query: 675 EPCFDAADFTRVGRDIFGQRSHVTNKKAIQWLRRHLAPR 791
EP FDA R+G D+ S N +WL+ L R
Sbjct: 146 EPVFDADTVLRIGTDLLYLVSDSGNALGARWLQAALGER 184
>sp|P56079|CDSA_DROME Phosphatidate cytidylyltransferase, photoreceptor-specific
(CDP-diglyceride synthetase) (CDP-diglyceride
pyrophosphorylase) (CDP-diacylglycerol synthase) (CDS)
(CTP:phosphatidate cytidylyltransferase) (CDP-DAG
synthase) (CDP-DG synthetase)
Length = 447
Score = 33.9 bits (76), Expect = 0.52
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 3/48 (6%)
Frame = -3
Query: 646 LSW---LTSNFISYKPSSIVHFGAEVHRAPSLKYFLINGRYASYSKYL 512
LSW LTSN+ Y + + +FG ++R LK+ + R+ S++ Y+
Sbjct: 142 LSWYFLLTSNYFFYGENLVDYFGVVINRVEYLKFLVTYHRFLSFALYI 189
>sp|Q9UQ07|MOK_HUMAN MAPK/MAK/MRK overlapping kinase (MOK protein kinase) (Renal tumor
antigen 1) (RAGE-1)
Length = 419
Score = 31.2 bits (69), Expect = 3.4
Identities = 13/38 (34%), Positives = 18/38 (47%)
Frame = +3
Query: 573 RWTSAPKCTMEEGLYDMKFDVSQDKPYVYVTTELEPCF 686
RW AP+C + +G Y K D+ Y L+P F
Sbjct: 165 RWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLF 202
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,993,609
Number of Sequences: 369166
Number of extensions: 1992366
Number of successful extensions: 4478
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4331
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4463
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7425705210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)