Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_K11-2
(464 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9H7F4|FA11B_HUMAN Protein FAM11B 49 4e-06
sp|Q8R3R5|FA11B_MOUSE Protein FAM11B 47 2e-05
sp|Q8K174|TM60_MOUSE Transmembrane protein 60 47 3e-05
sp|Q9H2L4|TM60_HUMAN Transmembrane protein 60 47 3e-05
sp|Q8NFB2|FA11A_HUMAN Protein FAM11A 45 8e-05
sp|Q5R8H8|FA11A_PONPY Protein FAM11A 45 8e-05
sp|P24877|NU2M_ASCSU NADH-ubiquinone oxidoreductase chain 2... 40 0.003
sp|Q7SYC7|FA11L_BRARE Protein FAM11-like 36 0.037
sp|Q85PQ0|NU2M_PARHE NADH-ubiquinone oxidoreductase chain 2... 31 1.2
sp|P75462|Y319_MYCPN Hypothetical protein MG226 homolog (F1... 31 1.6
>sp|Q9H7F4|FA11B_HUMAN Protein FAM11B
Length = 350
Score = 49.3 bits (116), Expect = 4e-06
Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 8/101 (7%)
Frame = +2
Query: 107 ILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNL------ILYFRRLSVI--RMTT 262
IL I +LK+D+ + W VF PL++ + L L +L+ R L V+ + T
Sbjct: 150 ILQFIFIALKLDRIIHWPWLVVFVPLWILMSFLCLVVLYYIVWSLLFLRSLDVVAEQRRT 209
Query: 263 ALWQLIKSLLFIMTLLIFKLFLCPKLEGTNAFSYTVITMPL 385
+ I + ++ LL F++ L +L+G N FSY I +PL
Sbjct: 210 HVTMAISWITIVVPLLTFEVLLVHRLDGHNTFSYVSIFVPL 250
Score = 30.8 bits (68), Expect = 1.6
Identities = 24/99 (24%), Positives = 50/99 (50%), Gaps = 6/99 (6%)
Frame = +2
Query: 107 ILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNLI---LYFRRLSVIRMTTALWQL 277
+LF +L L++D S+W VFAP+++ ++V + ++ R A +
Sbjct: 22 LLFSVLLPLRLDGIIQWSYWAVFAPIWLWKLLVVAGASVGAGVWARNPRYRTEGEACVEF 81
Query: 278 IKSLLFI---MTLLIFKLFLCPKLEGTNAFSYTVITMPL 385
L+ + + LL+F++ +C ++E F + ++ MPL
Sbjct: 82 KAMLIAVGIHLLLLMFEVLVCDRVERGTHF-WLLVFMPL 119
>sp|Q8R3R5|FA11B_MOUSE Protein FAM11B
Length = 350
Score = 47.0 bits (110), Expect = 2e-05
Identities = 31/101 (30%), Positives = 52/101 (51%), Gaps = 8/101 (7%)
Frame = +2
Query: 107 ILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNL------ILYFRRLSVI--RMTT 262
IL I +L++D+ + W VF PL++ + L L +L+ R L V+ + T
Sbjct: 150 ILQFIFIALRLDRIIHWPWLVVFVPLWILMSFLCLVVLYYIVWSLLFLRSLDVVAEQRRT 209
Query: 263 ALWQLIKSLLFIMTLLIFKLFLCPKLEGTNAFSYTVITMPL 385
+ I + ++ LLIF++ L +L+ N FSY I +PL
Sbjct: 210 HVTMAISWITIVVPLLIFEVLLVHRLDDHNTFSYISIFIPL 250
Score = 31.2 bits (69), Expect = 1.2
Identities = 23/99 (23%), Positives = 50/99 (50%), Gaps = 6/99 (6%)
Frame = +2
Query: 107 ILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNLI---LYFRRLSVIRMTTALWQL 277
+LF +L L++D S+W VFAP+++ +++ + ++ R A +
Sbjct: 22 LLFSVLLPLRLDGIIQWSYWAVFAPIWLWKLLVIVGASVGAGVWARNPRYRTEGEACVEF 81
Query: 278 IKSLLFI---MTLLIFKLFLCPKLEGTNAFSYTVITMPL 385
L+ + + LL+F++ +C ++E F + ++ MPL
Sbjct: 82 KAMLIAVGIHLLLLMFEILVCDRVERGTHF-WLLVFMPL 119
>sp|Q8K174|TM60_MOUSE Transmembrane protein 60
Length = 133
Score = 46.6 bits (109), Expect = 3e-05
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
Frame = +2
Query: 107 ILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNLIL--------YFRRLSVIRMTT 262
+LFLI+ LK+D+ A +W+ +F P+++ DTIL+ ++ + R +
Sbjct: 17 LLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVMLIVKMAGRCKSGFDPRHGSHNIKK 76
Query: 263 ALWQLIKSLLFIMTLLIFKLFLCPKLEGTNAFSYTVITMPLITLL 397
W LI LL L F L LC KLE + + + +PL LL
Sbjct: 77 KAWYLIAMLL----KLAFCLALCAKLEQFTTMNLSYVFIPLWALL 117
>sp|Q9H2L4|TM60_HUMAN Transmembrane protein 60
Length = 133
Score = 46.6 bits (109), Expect = 3e-05
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
Frame = +2
Query: 107 ILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNLIL--------YFRRLSVIRMTT 262
+LFLI+ LK+D+ A +W+ +F P+++ DTIL+ ++ + R +
Sbjct: 17 LLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVLLIVKMAGRCKSGFDPRHGSHNIKK 76
Query: 263 ALWQLIKSLLFIMTLLIFKLFLCPKLEGTNAFSYTVITMPLITLL 397
W LI LL L F L LC KLE + + + +PL LL
Sbjct: 77 KAWYLIAMLL----KLAFCLALCAKLEQFTTMNLSYVFIPLWALL 117
>sp|Q8NFB2|FA11A_HUMAN Protein FAM11A
Length = 350
Score = 45.1 bits (105), Expect = 8e-05
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 8/101 (7%)
Frame = +2
Query: 107 ILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNL------ILYFRRLSVI--RMTT 262
IL I +L++DK + W V PL++ + L L +L+ R + VI + T
Sbjct: 150 ILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRT 209
Query: 263 ALWQLIKSLLFIMTLLIFKLFLCPKLEGTNAFSYTVITMPL 385
+ + + ++ LL F++ L KL+G NAFS I +PL
Sbjct: 210 HITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPL 250
Score = 32.0 bits (71), Expect = 0.70
Identities = 24/99 (24%), Positives = 51/99 (51%), Gaps = 6/99 (6%)
Frame = +2
Query: 107 ILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNLI--LYFRRLSVIRMTTALWQLI 280
+LF +L +L++D S+W VFAP+++ +++ + + R R
Sbjct: 22 LLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEF 81
Query: 281 KSLLFI----MTLLIFKLFLCPKLEGTNAFSYTVITMPL 385
K++L + LL+F++ +C ++E + F + ++ MPL
Sbjct: 82 KAMLIAVGIHLLLLMFEVLVCDRIERGSHF-WLLVFMPL 119
>sp|Q5R8H8|FA11A_PONPY Protein FAM11A
Length = 350
Score = 45.1 bits (105), Expect = 8e-05
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 8/101 (7%)
Frame = +2
Query: 107 ILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNL------ILYFRRLSVI--RMTT 262
IL I +L++DK + W V PL++ + L L +L+ R + VI + T
Sbjct: 150 ILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRT 209
Query: 263 ALWQLIKSLLFIMTLLIFKLFLCPKLEGTNAFSYTVITMPL 385
+ + + ++ LL F++ L KL+G NAFS I +PL
Sbjct: 210 HITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPL 250
Score = 32.0 bits (71), Expect = 0.70
Identities = 24/99 (24%), Positives = 51/99 (51%), Gaps = 6/99 (6%)
Frame = +2
Query: 107 ILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNLI--LYFRRLSVIRMTTALWQLI 280
+LF +L +L++D S+W VFAP+++ +++ + + R R
Sbjct: 22 LLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEF 81
Query: 281 KSLLFI----MTLLIFKLFLCPKLEGTNAFSYTVITMPL 385
K++L + LL+F++ +C ++E + F + ++ MPL
Sbjct: 82 KAMLIAVGIHLLLLMFEVLVCDRIERGSHF-WLLVFMPL 119
>sp|P24877|NU2M_ASCSU NADH-ubiquinone oxidoreductase chain 2 (NADH dehydrogenase subunit
2)
Length = 300
Score = 39.7 bits (91), Expect = 0.003
Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 12/146 (8%)
Frame = +2
Query: 14 YKSYMVLLSFAEITYWIEITCFELTAHII------TFILFLILASLKVDKFANISWWYVF 175
YKS MV+ S E W+ +TCF ++I ++ ++ + V F ++W +
Sbjct: 145 YKSMMVISS-TESFNWVVLTCFLSVVNVIYLFFYYVVLMAFLMPNFNVKDFNFVNWEVLL 203
Query: 176 APLFVSDTILVYFNLILYFRRLSVIRMTTALWQLIKSLLFIMTLLIFKLFLC------PK 337
L V ++ + + + LS + L+ L L+ +++L F L+L K
Sbjct: 204 VFLNVPFSVSFFIKIFV----LSEVFKLDGLFLLFLLLMMFLSMLCFSLWLVNMSVKNMK 259
Query: 338 LEGTNAFSYTVITMPLITLLQIYMFS 415
+ G N + P++ IY FS
Sbjct: 260 MLGDNFKVLFFLVFPMMVFSVIYYFS 285
>sp|Q7SYC7|FA11L_BRARE Protein FAM11-like
Length = 351
Score = 36.2 bits (82), Expect = 0.037
Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 8/101 (7%)
Frame = +2
Query: 107 ILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNL------ILYFRRLSVI--RMTT 262
IL I +LK+D + W V PL++ + L L +L+ R + VI + T
Sbjct: 151 ILQFIFIALKLDGIISWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRT 210
Query: 263 ALWQLIKSLLFIMTLLIFKLFLCPKLEGTNAFSYTVITMPL 385
+ I + ++ LL F++ L KL+ + +Y + +PL
Sbjct: 211 HITMAISWMTIVVPLLTFEILLVHKLDNHYSPNYVPVFVPL 251
Score = 31.2 bits (69), Expect = 1.2
Identities = 23/99 (23%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Frame = +2
Query: 107 ILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNLI--LYFRRLSVIRMTTALWQLI 280
+LF +L SL++D S+W VFAP+++ +++ + + R
Sbjct: 22 LLFSVLLSLRLDGIIQWSYWAVFAPIWLWKLMVIIGASVGTGVWAHNPQYRAEGETCVEF 81
Query: 281 KSLLFI----MTLLIFKLFLCPKLEGTNAFSYTVITMPL 385
K++L + LL F++ +C ++E + + ++ MPL
Sbjct: 82 KAMLIAVGIHLLLLTFEVLVCERVERASIPYWLLVFMPL 120
Score = 29.3 bits (64), Expect = 4.5
Identities = 28/121 (23%), Positives = 51/121 (42%), Gaps = 12/121 (9%)
Frame = +2
Query: 71 TCFELTAHIIT------FILFLILASLKVDKFANISWWYVFAPLFVSDTILVYFNLILYF 232
TC E A +I + F +L +V++ + W VF PLF
Sbjct: 77 TCVEFKAMLIAVGIHLLLLTFEVLVCERVERASIPYWLLVFMPLFF-------------- 122
Query: 233 RRLSVIRMTTALW------QLIKSLLFIMTLLIFKLFLCPKLEGTNAFSYTVITMPLITL 394
+S + + +W L +L + +L F +F+ KL+G ++ + V+ +PL L
Sbjct: 123 --VSPVSVAACVWGFRHDRSLELEILCSVNILQF-IFIALKLDGIISWPWLVVCVPLWIL 179
Query: 395 L 397
+
Sbjct: 180 M 180
>sp|Q85PQ0|NU2M_PARHE NADH-ubiquinone oxidoreductase chain 2 (NADH dehydrogenase subunit
2)
Length = 347
Score = 31.2 bits (69), Expect = 1.2
Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Frame = +2
Query: 203 LVYFNLILYFRRLSVIRMTTALWQLIKSLLFIM-TLLIFKLFLCPKLEGTNAFSYTVITM 379
++ ++ I + +S I + L+ +++IM TL F LF+ T A S T M
Sbjct: 178 ILAYSSIAHMGWMSTILIYNPTMMLLNLIIYIMMTLSTFMLFMHNSTTTTLALSQTWNKM 237
Query: 380 PLITLLQIYMFSLCIG 427
PLIT L I M L +G
Sbjct: 238 PLITSL-ILMLMLSLG 252
>sp|P75462|Y319_MYCPN Hypothetical protein MG226 homolog (F10_orf503)
Length = 503
Score = 30.8 bits (68), Expect = 1.6
Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 7/70 (10%)
Frame = +2
Query: 32 LLSFAEITYWIEITC-----FELTAHIITFILFLILASLKVDKFANISWWYV--FAPLFV 190
L+ F I+ +E+ L + IT+I F ++ + K + A++SWW + + F
Sbjct: 389 LVMFDAISVLVEVAIELAVLISLIQYFITYIFFFMILAKK-EGSASVSWWEIASYGVSFA 447
Query: 191 SDTILVYFNL 220
T+L++ NL
Sbjct: 448 IITVLLFVNL 457
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,148,555
Number of Sequences: 369166
Number of extensions: 798501
Number of successful extensions: 1820
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1770
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1812
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2633927485
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)