Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_K04
(852 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q27655|ENO_FASHE Enolase (2-phosphoglycerate dehydratase... 316 5e-86
sp|P33676|ENO_SCHJA Enolase (2-phosphoglycerate dehydratase... 314 2e-85
sp|Q27527|ENO_CAEEL Enolase (2-phosphoglycerate dehydratase... 309 7e-84
sp|O02654|ENO_LOLPE Enolase (2-phosphoglycerate dehydratase... 306 6e-83
sp|P09104|ENOG_HUMAN Gamma-enolase (2-phospho-D-glycerate h... 305 8e-83
sp|P17183|ENOG_MOUSE Gamma-enolase (2-phospho-D-glycerate h... 305 1e-82
sp|O57391|ENOG_CHICK Gamma-enolase (2-phospho-D-glycerate h... 304 2e-82
sp|P07323|ENOG_RAT Gamma-enolase (2-phospho-D-glycerate hyd... 303 3e-82
sp|Q27877|ENO_SCHMA Enolase (2-phosphoglycerate dehydratase... 302 9e-82
sp|Q9PVK2|ENOA_ALLMI Alpha-enolase (2-phospho-D-glycerate h... 301 2e-81
>sp|Q27655|ENO_FASHE Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate
hydro-lyase)
Length = 431
Score = 316 bits (810), Expect = 5e-86
Identities = 154/203 (75%), Positives = 169/203 (83%)
Frame = -2
Query: 701 AIESAGYCGKVLIGMDVAASEFYKDGRYDLDFKNPKSSPNKWLTSDQLGEVYNSMCRKYP 522
AI+ AGY GKV I MD AASEFYK+G+YDLDFKNPKS + W+TSD + +VY M YP
Sbjct: 229 AIDKAGYTGKVXIAMDCAASEFYKEGKYDLDFKNPKSQASSWITSDAMADVYKKMMSTYP 288
Query: 521 IVTIEDPFDQDDWDAWIKFNGNSKIQIVGDDLLVTNPKRVQRAIDCGACNALLLKVNQIG 342
IV+IEDPFDQDDW AW K G KIQIVGDDL VTNP RVQ+AID ACN LLLKVNQIG
Sbjct: 289 IVSIEDPFDQDDWPAWTKLTGECKIQIVGDDLTVTNPLRVQKAIDQKACNCLLLKVNQIG 348
Query: 341 TVTESIEACRMAQRAGWGVMVSHRSGETEDTTIADLVVGLRTGQIKTGAPCRSERLAKYN 162
+V+ESI+AC+MAQ AGWGVMVSHRSGETED IADLVVGLRTGQIKTGAPCRSERLAKYN
Sbjct: 349 SVSESIKACKMAQEAGWGVMVSHRSGETEDNFIADLVVGLRTGQIKTGAPCRSERLAKYN 408
Query: 161 QLLRIEEELGIFAKYAGASFHNP 93
QLLRIEE+LG AKYAG +F P
Sbjct: 409 QLLRIEEDLGGAAKYAGENFRRP 431
>sp|P33676|ENO_SCHJA Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate
hydro-lyase)
Length = 434
Score = 314 bits (805), Expect = 2e-85
Identities = 151/204 (74%), Positives = 173/204 (84%)
Frame = -2
Query: 704 QAIESAGYCGKVLIGMDVAASEFYKDGRYDLDFKNPKSSPNKWLTSDQLGEVYNSMCRKY 525
+AI+ AGY GKV IGMD AASE+YK G+YDLDFKNP+S+ + WL+ D++ VY M +KY
Sbjct: 229 EAIKIAGYTGKVEIGMDCAASEYYKKGKYDLDFKNPQSAESHWLSPDEMANVYKEMIQKY 288
Query: 524 PIVTIEDPFDQDDWDAWIKFNGNSKIQIVGDDLLVTNPKRVQRAIDCGACNALLLKVNQI 345
PIV+IEDPFDQDDWDAW K ++ IQIVGDDL VTNPKR+++AI ACN LLLKVNQI
Sbjct: 289 PIVSIEDPFDQDDWDAWPKLTASTNIQIVGDDLTVTNPKRIEKAIKVKACNCLLLKVNQI 348
Query: 344 GTVTESIEACRMAQRAGWGVMVSHRSGETEDTTIADLVVGLRTGQIKTGAPCRSERLAKY 165
G++TESIEAC+MAQ+AGWGVMVSHRSGETED IADLVVGL TGQIKTGAPCRSERLAKY
Sbjct: 349 GSITESIEACKMAQKAGWGVMVSHRSGETEDNFIADLVVGLCTGQIKTGAPCRSERLAKY 408
Query: 164 NQLLRIEEELGIFAKYAGASFHNP 93
NQLLRIEEELG AKYAG F +P
Sbjct: 409 NQLLRIEEELGSTAKYAGKHFRHP 432
>sp|Q27527|ENO_CAEEL Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate
hydro-lyase)
Length = 434
Score = 309 bits (791), Expect = 7e-84
Identities = 149/203 (73%), Positives = 172/203 (84%)
Frame = -2
Query: 701 AIESAGYCGKVLIGMDVAASEFYKDGRYDLDFKNPKSSPNKWLTSDQLGEVYNSMCRKYP 522
AI+ AGY GK+ IGMDVAASEF+KDG+YDLDFKNP S +KWL+ +QL E+Y S ++YP
Sbjct: 230 AIDKAGYTGKISIGMDVAASEFFKDGKYDLDFKNPASDSSKWLSGEQLTELYQSFIKEYP 289
Query: 521 IVTIEDPFDQDDWDAWIKFNGNSKIQIVGDDLLVTNPKRVQRAIDCGACNALLLKVNQIG 342
+V+IED FDQDDWD W KF+G + IQ+VGDDL VTNPKR+Q AID +CN LLLKVNQIG
Sbjct: 290 VVSIEDAFDQDDWDNWGKFHGATSIQLVGDDLTVTNPKRIQTAIDKKSCNCLLLKVNQIG 349
Query: 341 TVTESIEACRMAQRAGWGVMVSHRSGETEDTTIADLVVGLRTGQIKTGAPCRSERLAKYN 162
+VTESIEA ++++ GWGVMVSHRSGETEDT IADLVVGL TGQIKTGAPCRSERLAKYN
Sbjct: 350 SVTESIEAAKLSRANGWGVMVSHRSGETEDTFIADLVVGLATGQIKTGAPCRSERLAKYN 409
Query: 161 QLLRIEEELGIFAKYAGASFHNP 93
QLLRIEEELG A YAG +F NP
Sbjct: 410 QLLRIEEELGADAVYAGHNFRNP 432
>sp|O02654|ENO_LOLPE Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate
hydro-lyase)
Length = 434
Score = 306 bits (783), Expect = 6e-83
Identities = 151/205 (73%), Positives = 171/205 (83%)
Frame = -2
Query: 701 AIESAGYCGKVLIGMDVAASEFYKDGRYDLDFKNPKSSPNKWLTSDQLGEVYNSMCRKYP 522
AI +AGY ++ IGMDVAASEF K+ +YDLDFKNP S+PN WLTSDQL +VY + YP
Sbjct: 230 AIANAGYTAEIEIGMDVAASEFCKEKKYDLDFKNPDSNPNDWLTSDQLADVYKDFVKNYP 289
Query: 521 IVTIEDPFDQDDWDAWIKFNGNSKIQIVGDDLLVTNPKRVQRAIDCGACNALLLKVNQIG 342
+V+IEDPFDQDDW+A+ K + IQIVGDDLLVTNPKRVQ+ ID A NALLLKVNQIG
Sbjct: 290 VVSIEDPFDQDDWEAYTKMTKDMDIQIVGDDLLVTNPKRVQKGIDLKAANALLLKVNQIG 349
Query: 341 TVTESIEACRMAQRAGWGVMVSHRSGETEDTTIADLVVGLRTGQIKTGAPCRSERLAKYN 162
+VTESI+AC+M+Q AGWGVMVSHRSGETEDT IADLVVGL TGQIKTGAPCRSERLAKYN
Sbjct: 350 SVTESIQACKMSQDAGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYN 409
Query: 161 QLLRIEEELGIFAKYAGASFHNP*K 87
Q+LRIEEELG A +AG F NP K
Sbjct: 410 QILRIEEELGDKAVFAGKKFRNPLK 434
>sp|P09104|ENOG_HUMAN Gamma-enolase (2-phospho-D-glycerate hydro-lyase) (Neural enolase)
(Neuron-specific enolase) (NSE) (Enolase 2)
Length = 434
Score = 305 bits (782), Expect = 8e-83
Identities = 146/204 (71%), Positives = 174/204 (85%)
Frame = -2
Query: 704 QAIESAGYCGKVLIGMDVAASEFYKDGRYDLDFKNPKSSPNKWLTSDQLGEVYNSMCRKY 525
+AI+ AGY K++IGMDVAASEFY+DG+YDLDFK+P + P++++T DQLG +Y R Y
Sbjct: 229 EAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSP-TDPSRYITGDQLGALYQDFVRDY 287
Query: 524 PIVTIEDPFDQDDWDAWIKFNGNSKIQIVGDDLLVTNPKRVQRAIDCGACNALLLKVNQI 345
P+V+IEDPFDQDDW AW KF N IQIVGDDL VTNPKR++RA++ ACN LLLKVNQI
Sbjct: 288 PVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQI 347
Query: 344 GTVTESIEACRMAQRAGWGVMVSHRSGETEDTTIADLVVGLRTGQIKTGAPCRSERLAKY 165
G+VTE+I+AC++AQ GWGVMVSHRSGETEDT IADLVVGL TGQIKTGAPCRSERLAKY
Sbjct: 348 GSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKY 407
Query: 164 NQLLRIEEELGIFAKYAGASFHNP 93
NQL+RIEEELG A++AG +F NP
Sbjct: 408 NQLMRIEEELGDEARFAGHNFRNP 431
>sp|P17183|ENOG_MOUSE Gamma-enolase (2-phospho-D-glycerate hydro-lyase) (Neural enolase)
(Neuron-specific enolase) (NSE) (Enolase 2)
Length = 434
Score = 305 bits (781), Expect = 1e-82
Identities = 146/204 (71%), Positives = 174/204 (85%)
Frame = -2
Query: 704 QAIESAGYCGKVLIGMDVAASEFYKDGRYDLDFKNPKSSPNKWLTSDQLGEVYNSMCRKY 525
+AI+ AGY K++IGMDVAASEFY+DG+YDLDFK+P + P++++T DQLG +Y R Y
Sbjct: 229 EAIDKAGYTEKMVIGMDVAASEFYRDGKYDLDFKSP-ADPSRYITGDQLGALYQDFVRNY 287
Query: 524 PIVTIEDPFDQDDWDAWIKFNGNSKIQIVGDDLLVTNPKRVQRAIDCGACNALLLKVNQI 345
P+V+IEDPFDQDDW AW KF N IQIVGDDL VTNPKR++RA++ ACN LLLKVNQI
Sbjct: 288 PVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQI 347
Query: 344 GTVTESIEACRMAQRAGWGVMVSHRSGETEDTTIADLVVGLRTGQIKTGAPCRSERLAKY 165
G+VTE+I+AC++AQ GWGVMVSHRSGETEDT IADLVVGL TGQIKTGAPCRSERLAKY
Sbjct: 348 GSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKY 407
Query: 164 NQLLRIEEELGIFAKYAGASFHNP 93
NQL+RIEEELG A++AG +F NP
Sbjct: 408 NQLMRIEEELGDEARFAGHNFRNP 431
>sp|O57391|ENOG_CHICK Gamma-enolase (2-phospho-D-glycerate hydro-lyase) (Neural enolase)
(NSE)
Length = 434
Score = 304 bits (778), Expect = 2e-82
Identities = 143/204 (70%), Positives = 176/204 (86%)
Frame = -2
Query: 704 QAIESAGYCGKVLIGMDVAASEFYKDGRYDLDFKNPKSSPNKWLTSDQLGEVYNSMCRKY 525
+AI+ AGY K++IGMDVAASEFY+DG+YDLDFK+P P++++++D+LG++Y S R Y
Sbjct: 229 EAIDKAGYTDKIVIGMDVAASEFYRDGKYDLDFKSP-DDPSRYISADELGDLYQSFVRAY 287
Query: 524 PIVTIEDPFDQDDWDAWIKFNGNSKIQIVGDDLLVTNPKRVQRAIDCGACNALLLKVNQI 345
P+++IEDPFDQDDW+AW KF N IQIVGDDL VTNPKR++RA++ ACN LLLKVNQI
Sbjct: 288 PVLSIEDPFDQDDWEAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQI 347
Query: 344 GTVTESIEACRMAQRAGWGVMVSHRSGETEDTTIADLVVGLRTGQIKTGAPCRSERLAKY 165
G+VTE+I+AC++AQ GWGVMVSHRSGETEDT IADLVV L TGQIKTGAPCRSERLAKY
Sbjct: 348 GSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVALCTGQIKTGAPCRSERLAKY 407
Query: 164 NQLLRIEEELGIFAKYAGASFHNP 93
NQL+RIEEELG A++AG +F NP
Sbjct: 408 NQLMRIEEELGDEARFAGHNFRNP 431
>sp|P07323|ENOG_RAT Gamma-enolase (2-phospho-D-glycerate hydro-lyase) (Neural enolase)
(Neuron-specific enolase) (NSE) (Enolase 2)
Length = 434
Score = 303 bits (777), Expect = 3e-82
Identities = 146/204 (71%), Positives = 173/204 (84%)
Frame = -2
Query: 704 QAIESAGYCGKVLIGMDVAASEFYKDGRYDLDFKNPKSSPNKWLTSDQLGEVYNSMCRKY 525
+AI+ AGY K++IGMDVAASEFY+DG+YDLDFK+P + P++ +T DQLG +Y R Y
Sbjct: 229 EAIDKAGYTEKMVIGMDVAASEFYRDGKYDLDFKSP-ADPSRCITGDQLGALYQDFVRNY 287
Query: 524 PIVTIEDPFDQDDWDAWIKFNGNSKIQIVGDDLLVTNPKRVQRAIDCGACNALLLKVNQI 345
P+V+IEDPFDQDDW AW KF N IQIVGDDL VTNPKR++RA++ ACN LLLKVNQI
Sbjct: 288 PVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQI 347
Query: 344 GTVTESIEACRMAQRAGWGVMVSHRSGETEDTTIADLVVGLRTGQIKTGAPCRSERLAKY 165
G+VTE+I+AC++AQ GWGVMVSHRSGETEDT IADLVVGL TGQIKTGAPCRSERLAKY
Sbjct: 348 GSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKY 407
Query: 164 NQLLRIEEELGIFAKYAGASFHNP 93
NQL+RIEEELG A++AG +F NP
Sbjct: 408 NQLMRIEEELGEEARFAGHNFRNP 431
>sp|Q27877|ENO_SCHMA Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate
hydro-lyase)
Length = 434
Score = 302 bits (773), Expect = 9e-82
Identities = 145/204 (71%), Positives = 171/204 (83%)
Frame = -2
Query: 704 QAIESAGYCGKVLIGMDVAASEFYKDGRYDLDFKNPKSSPNKWLTSDQLGEVYNSMCRKY 525
+AI+ AGY GKV IGMD AASEF+K+G+YDLDFKNP S+ + WL+ D + +Y M K+
Sbjct: 229 EAIKIAGYTGKVEIGMDCAASEFHKNGKYDLDFKNPHSAESTWLSPDAMANMYKQMISKF 288
Query: 524 PIVTIEDPFDQDDWDAWIKFNGNSKIQIVGDDLLVTNPKRVQRAIDCGACNALLLKVNQI 345
PIV+IEDPFDQDDW+ W K ++ IQIVGDDL VTNPKR+++AI ACN LLLKVNQI
Sbjct: 289 PIVSIEDPFDQDDWETWPKLTSSTNIQIVGDDLTVTNPKRIKQAIASKACNCLLLKVNQI 348
Query: 344 GTVTESIEACRMAQRAGWGVMVSHRSGETEDTTIADLVVGLRTGQIKTGAPCRSERLAKY 165
G++TESIEAC++AQ +GWGVMVSHRSGETEDT IADLVVGL TGQIKTGAPCRS+RLAKY
Sbjct: 349 GSLTESIEACKLAQDSGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSDRLAKY 408
Query: 164 NQLLRIEEELGIFAKYAGASFHNP 93
NQLLRIEEELG AKYAG +F +P
Sbjct: 409 NQLLRIEEELGTAAKYAGKNFRHP 432
>sp|Q9PVK2|ENOA_ALLMI Alpha-enolase (2-phospho-D-glycerate hydro-lyase) (Phosphopyruvate
hydratase)
Length = 434
Score = 301 bits (770), Expect = 2e-81
Identities = 143/203 (70%), Positives = 171/203 (84%)
Frame = -2
Query: 701 AIESAGYCGKVLIGMDVAASEFYKDGRYDLDFKNPKSSPNKWLTSDQLGEVYNSMCRKYP 522
AI AGY K++IGMDVAASEFY+DG+YDLDFK+P P++++T DQL ++Y S + YP
Sbjct: 230 AINKAGYSDKIVIGMDVAASEFYRDGKYDLDFKSP-DDPSRYITPDQLADLYKSFVKNYP 288
Query: 521 IVTIEDPFDQDDWDAWIKFNGNSKIQIVGDDLLVTNPKRVQRAIDCGACNALLLKVNQIG 342
+V+IEDPFDQDDW AW KF + IQ+VGDDL VTNPKR+ +A+D ACN LLLKVNQIG
Sbjct: 289 VVSIEDPFDQDDWAAWKKFTASVGIQVVGDDLTVTNPKRIAKAVDDKACNCLLLKVNQIG 348
Query: 341 TVTESIEACRMAQRAGWGVMVSHRSGETEDTTIADLVVGLRTGQIKTGAPCRSERLAKYN 162
+VTES++AC++AQ GWGVMVSHRSGETEDT IADLVVGL TGQIKTGAPCRSERLAKYN
Sbjct: 349 SVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYN 408
Query: 161 QLLRIEEELGIFAKYAGASFHNP 93
Q+LRIEEELG A++AG +F NP
Sbjct: 409 QILRIEEELGSKARFAGRNFRNP 431
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,028,470
Number of Sequences: 369166
Number of extensions: 1830362
Number of successful extensions: 5188
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4691
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4795
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8390082510
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)