Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_J02
(748 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q13409|DYI2_HUMAN Dynein intermediate chain 2, cytosolic... 228 1e-59
sp|O88487|DYI2_MOUSE Dynein intermediate chain 2, cytosolic... 228 1e-59
sp|Q62871|DYI2_RAT Dynein intermediate chain 2, cytosolic (... 226 7e-59
sp|O14576|DYI1_HUMAN Dynein intermediate chain 1, cytosolic... 225 1e-58
sp|Q63100|DYI1_RAT Dynein intermediate chain 1, cytosolic (... 224 1e-58
sp|O88485|DYI1_MOUSE Dynein intermediate chain 1, cytosolic... 221 1e-57
sp|Q24246|DYIN_DROME Dynein intermediate chain, cytosolic (... 215 9e-56
sp|P54703|DYIN_DICDI Dynein intermediate chain, cytosolic (... 152 1e-36
sp|P27766|DYI3_CHLRE Dynein, 70 kDa intermediate chain, fla... 70 6e-12
sp|Q16959|DYI2_ANTCR Dynein intermediate chain 2, ciliary 65 3e-10
>sp|Q13409|DYI2_HUMAN Dynein intermediate chain 2, cytosolic (DH IC-2) (Cytoplasmic dynein
intermediate chain 2)
Length = 638
Score = 228 bits (582), Expect = 1e-59
Identities = 109/194 (56%), Positives = 133/194 (68%)
Frame = +2
Query: 2 FLSNDVNNFLVGSEDGMVYPGIRHGGKAGLSEGFEGHLGPISGLSSHKVPGAVDFSHLFL 181
F DVNNF+VGSE+G VY RHG KAG+SE FEGH GPI+G+ H GAVDFSHLF+
Sbjct: 439 FPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFV 498
Query: 182 TSSFDWTVKLWSGRDSGSRPLHSFEDNGDYVYDVAWSPVHPAVFASVDGQGLLDIWKLTA 361
TSSFDWTVKLW+ +++ +PL+SFEDN DYVYDV WSP HPA+FA VDG G LD+W L
Sbjct: 499 TSSFDWTVKLWTTKNN--KPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNN 556
Query: 362 DTEVPISRTQVNPMTALNKCSWHKTGAHVAVGDDSGRISIMDVNEQLYQPSSSAWSDLSH 541
DTEVP + V ALN+ W +G +AVGD G+I I DV EQ+ P + W+
Sbjct: 557 DTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGR 616
Query: 542 TLTELQLASADIKE 583
TL E+ AD +E
Sbjct: 617 TLAEINANRADAEE 630
>sp|O88487|DYI2_MOUSE Dynein intermediate chain 2, cytosolic (DH IC-2) (Cytoplasmic
dynein intermediate chain 2)
Length = 612
Score = 228 bits (582), Expect = 1e-59
Identities = 109/194 (56%), Positives = 133/194 (68%)
Frame = +2
Query: 2 FLSNDVNNFLVGSEDGMVYPGIRHGGKAGLSEGFEGHLGPISGLSSHKVPGAVDFSHLFL 181
F DVNNF+VGSE+G VY RHG KAG+SE FEGH GPI+G+ H GAVDFSHLF+
Sbjct: 413 FPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFV 472
Query: 182 TSSFDWTVKLWSGRDSGSRPLHSFEDNGDYVYDVAWSPVHPAVFASVDGQGLLDIWKLTA 361
TSSFDWTVKLW+ +++ +PL+SFEDN DYVYDV WSP HPA+FA VDG G LD+W L
Sbjct: 473 TSSFDWTVKLWTTKNN--KPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWNLNN 530
Query: 362 DTEVPISRTQVNPMTALNKCSWHKTGAHVAVGDDSGRISIMDVNEQLYQPSSSAWSDLSH 541
DTEVP + V ALN+ W +G +AVGD G+I I DV EQ+ P + W+
Sbjct: 531 DTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGR 590
Query: 542 TLTELQLASADIKE 583
TL E+ AD +E
Sbjct: 591 TLAEINANRADAEE 604
>sp|Q62871|DYI2_RAT Dynein intermediate chain 2, cytosolic (DH IC-2) (Cytoplasmic dynein
intermediate chain 2)
Length = 638
Score = 226 bits (575), Expect = 7e-59
Identities = 109/194 (56%), Positives = 133/194 (68%)
Frame = +2
Query: 2 FLSNDVNNFLVGSEDGMVYPGIRHGGKAGLSEGFEGHLGPISGLSSHKVPGAVDFSHLFL 181
F DVNNF+VGSE+G VY RHG KAG+SE FEGH GPI+G+ H GAVDFSHLF+
Sbjct: 439 FPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFV 498
Query: 182 TSSFDWTVKLWSGRDSGSRPLHSFEDNGDYVYDVAWSPVHPAVFASVDGQGLLDIWKLTA 361
TSSFDWTVKLWS +++ +PL+SFEDN DYVYDV SP HPA+FA VDG G LD+W L
Sbjct: 499 TSSFDWTVKLWSTKNN--KPLYSFEDNSDYVYDVIGSPTHPALFACVDGMGRLDLWNLNN 556
Query: 362 DTEVPISRTQVNPMTALNKCSWHKTGAHVAVGDDSGRISIMDVNEQLYQPSSSAWSDLSH 541
DTEVP + V ALN+ W +G +AVGD G+I I DV EQ+ P + W+
Sbjct: 557 DTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGR 616
Query: 542 TLTELQLASADIKE 583
TL E+ + AD +E
Sbjct: 617 TLAEINASRADAEE 630
>sp|O14576|DYI1_HUMAN Dynein intermediate chain 1, cytosolic (DH IC-1) (Cytoplasmic dynein
intermediate chain 1)
Length = 645
Score = 225 bits (573), Expect = 1e-58
Identities = 107/196 (54%), Positives = 136/196 (69%)
Frame = +2
Query: 2 FLSNDVNNFLVGSEDGMVYPGIRHGGKAGLSEGFEGHLGPISGLSSHKVPGAVDFSHLFL 181
F + DVNNF+VGSE+G VY RHG KAG+ E FEGH GP++G++ H G +DFSHLF+
Sbjct: 447 FPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFV 506
Query: 182 TSSFDWTVKLWSGRDSGSRPLHSFEDNGDYVYDVAWSPVHPAVFASVDGQGLLDIWKLTA 361
TSSFDWTVKLW+ + + +PL+SFEDN DYVYDV WSPVHPA+FA VDG G LD+W L
Sbjct: 507 TSSFDWTVKLWTTKHN--KPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNN 564
Query: 362 DTEVPISRTQVNPMTALNKCSWHKTGAHVAVGDDSGRISIMDVNEQLYQPSSSAWSDLSH 541
DTEVP + + +ALN+ W + G VAVGD GRI + DV E L P + W+ +
Sbjct: 565 DTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGE-LAVPHNDEWTRFAR 623
Query: 542 TLTELQLASADIKELG 589
TL E++ AD +E G
Sbjct: 624 TLVEIRANRADSEEEG 639
>sp|Q63100|DYI1_RAT Dynein intermediate chain 1, cytosolic (DH IC-1) (Cytoplasmic dynein
intermediate chain 1)
Length = 643
Score = 224 bits (572), Expect = 1e-58
Identities = 108/196 (55%), Positives = 136/196 (69%)
Frame = +2
Query: 2 FLSNDVNNFLVGSEDGMVYPGIRHGGKAGLSEGFEGHLGPISGLSSHKVPGAVDFSHLFL 181
F + DVNNF+VGSE+G VY RHG KAG+ E FEGH GP++G++ H G +DFSHLF+
Sbjct: 445 FPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFV 504
Query: 182 TSSFDWTVKLWSGRDSGSRPLHSFEDNGDYVYDVAWSPVHPAVFASVDGQGLLDIWKLTA 361
TSSFDWTVKLW+ + + +PL+SFEDN DYVYDV WSPVHPA+FA VDG G LD+W L +
Sbjct: 505 TSSFDWTVKLWTTKHN--KPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNS 562
Query: 362 DTEVPISRTQVNPMTALNKCSWHKTGAHVAVGDDSGRISIMDVNEQLYQPSSSAWSDLSH 541
DTEVP + + ALN+ W + G VAVGD GRI I DV E L P + W+ +
Sbjct: 563 DTEVPTASVAIEGAYALNRVRWAQGGKEVAVGDSEGRIWIYDVGE-LAVPHNDEWTRFAR 621
Query: 542 TLTELQLASADIKELG 589
TL E++ AD +E G
Sbjct: 622 TLVEIRANRADSEEEG 637
>sp|O88485|DYI1_MOUSE Dynein intermediate chain 1, cytosolic (DH IC-1) (Cytoplasmic dynein
intermediate chain 1)
Length = 628
Score = 221 bits (564), Expect = 1e-57
Identities = 106/196 (54%), Positives = 136/196 (69%)
Frame = +2
Query: 2 FLSNDVNNFLVGSEDGMVYPGIRHGGKAGLSEGFEGHLGPISGLSSHKVPGAVDFSHLFL 181
F + DVNNF+VGSE+G VY RHG KAG+ E FEGH GP++G++ H G +DFSHLF+
Sbjct: 430 FPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFV 489
Query: 182 TSSFDWTVKLWSGRDSGSRPLHSFEDNGDYVYDVAWSPVHPAVFASVDGQGLLDIWKLTA 361
TSSFDWTVKLW+ + + +P++S EDN DYVYDV WSPVHPA+FA VDG G LD+W L +
Sbjct: 490 TSSFDWTVKLWTTKHN--KPVYSSEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNS 547
Query: 362 DTEVPISRTQVNPMTALNKCSWHKTGAHVAVGDDSGRISIMDVNEQLYQPSSSAWSDLSH 541
DTEVP + + +ALN+ W + G VAVGD GRI I DV E L P + W+ +
Sbjct: 548 DTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGE-LAVPHNDEWTRFAR 606
Query: 542 TLTELQLASADIKELG 589
TL E++ AD +E G
Sbjct: 607 TLVEIRANRADSEEEG 622
>sp|Q24246|DYIN_DROME Dynein intermediate chain, cytosolic (DH IC) (Cytoplasmic dynein
intermediate chain) (Short wing protein)
Length = 663
Score = 215 bits (548), Expect = 9e-56
Identities = 100/191 (52%), Positives = 138/191 (72%)
Frame = +2
Query: 2 FLSNDVNNFLVGSEDGMVYPGIRHGGKAGLSEGFEGHLGPISGLSSHKVPGAVDFSHLFL 181
F +N++N+ ++GSEDG VY RHG ++G++E +E HLGPI+G+S+H + DF HLFL
Sbjct: 473 FPANEINSLVMGSEDGYVYSASRHGLRSGVNEVYERHLGPITGISTHYNQLSPDFGHLFL 532
Query: 182 TSSFDWTVKLWSGRDSGSRPLHSFEDNGDYVYDVAWSPVHPAVFASVDGQGLLDIWKLTA 361
TSS DWT+KLWS +D+ +PL+SFEDN DYV DVAWSPVHPA+FA+VDG G LD+W L
Sbjct: 533 TSSIDWTIKLWSLKDT--KPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQ 590
Query: 362 DTEVPISRTQVNPMTALNKCSWHKTGAHVAVGDDSGRISIMDVNEQLYQPSSSAWSDLSH 541
DTEVP + V ALN+ SW +G HV +GD++G++ + DV E L QPS WS +
Sbjct: 591 DTEVPTASIVVAGAPALNRVSWTPSGLHVCIGDEAGKLYVYDVAENLAQPSRDEWSRFNT 650
Query: 542 TLTELQLASAD 574
L+E+++ +D
Sbjct: 651 HLSEIKMNQSD 661
>sp|P54703|DYIN_DICDI Dynein intermediate chain, cytosolic (DH IC) (Cytoplasmic dynein
intermediate chain)
Length = 652
Score = 152 bits (383), Expect = 1e-36
Identities = 74/185 (40%), Positives = 113/185 (61%)
Frame = +2
Query: 2 FLSNDVNNFLVGSEDGMVYPGIRHGGKAGLSEGFEGHLGPISGLSSHKVPGAVDFSHLFL 181
F N++N+F +G+E+G++ RHG + ++E ++ LGPI+ + H G DFS FL
Sbjct: 454 FPENELNHFYIGTEEGVICQAGRHGNRIVMNERYK-ELGPITSVDLHPSKGGADFSQYFL 512
Query: 182 TSSFDWTVKLWSGRDSGSRPLHSFEDNGDYVYDVAWSPVHPAVFASVDGQGLLDIWKLTA 361
+SS DWT KLWS + PL+SFED DYVYD WSPVHP++F++ DG G L +W L
Sbjct: 513 SSSTDWTCKLWSSKKE--TPLYSFEDYVDYVYDARWSPVHPSIFSTGDGSGTLSLWDLNQ 570
Query: 362 DTEVPISRTQVNPMTALNKCSWHKTGAHVAVGDDSGRISIMDVNEQLYQPSSSAWSDLSH 541
D E PI R +++ ++N+ +W G + VGD G +S+ D +E P+S +S
Sbjct: 571 DLEGPIFRHKIS-NRSVNRLAWSHDGKRILVGDSGGSLSLFDSSE-FSSPTSEEYSQFED 628
Query: 542 TLTEL 556
+T++
Sbjct: 629 VMTKM 633
>sp|P27766|DYI3_CHLRE Dynein, 70 kDa intermediate chain, flagellar outer arm (IC69)
(IC70)
Length = 567
Score = 70.1 bits (170), Expect = 6e-12
Identities = 46/174 (26%), Positives = 81/174 (46%), Gaps = 2/174 (1%)
Frame = +2
Query: 23 NFLVGSEDGMVYPGIRHGGKA--GLSEGFEGHLGPISGLSSHKVPGAVDFSHLFLTSSFD 196
NF+VG+E G ++ R + GH GPI GL + F+ + S D
Sbjct: 330 NFMVGTEQGQIFSCNRKAKNPVDRVKYVLSGHHGPIYGLRRNP------FNSKYFLSIGD 383
Query: 197 WTVKLWSGRDSGSRPLHSFEDNGDYVYDVAWSPVHPAVFASVDGQGLLDIWKLTADTEVP 376
WT ++W + P+ + + + Y+ WSP P VF ++ G +D+W L P
Sbjct: 384 WTARVWVEDTAVKTPILTTKYHPTYLTGGTWSPSRPGVFFTIKMDGAMDVWDLYYKHNEP 443
Query: 377 ISRTQVNPMTALNKCSWHKTGAHVAVGDDSGRISIMDVNEQLYQPSSSAWSDLS 538
QV+ + AL + ++G VAVG G S++ ++ L + S + ++++
Sbjct: 444 TLTVQVSDL-ALTAFAVQESGGTVAVGTSDGCTSVLQLSTGLSEASPAEKANIN 496
>sp|Q16959|DYI2_ANTCR Dynein intermediate chain 2, ciliary
Length = 702
Score = 64.7 bits (156), Expect = 3e-10
Identities = 54/186 (29%), Positives = 89/186 (47%), Gaps = 3/186 (1%)
Frame = +2
Query: 26 FLVGSEDGMVYPGIRHGGKAGLSEGFEGHLGPISGLSSHKVPGAVDFSHLFLTSSFDWTV 205
FLVG+E+G ++ + L + FE H ++ +KV +F++ S DW+V
Sbjct: 511 FLVGTEEGKIHKCSKAYSSQFL-DTFEAH-----HMAVYKVMWNHFHPKIFISCSADWSV 564
Query: 206 KLWSGRDSGSRPLHSFEDNGDYVYDVAWSPVHPAVFASVDGQGLLDIWKLTADTEVPISR 385
K+W + P+ +F D G V DVAW+P VFA+V G + ++ L + PI
Sbjct: 565 KIWD-HTYRNGPMFTF-DLGSAVGDVAWAPYSSTVFAAVTADGKVHVFDLNLNKYEPICE 622
Query: 386 TQV--NPMTALNKCSWHKTGAHVAVGDDSGRISIMDVNEQLYQ-PSSSAWSDLSHTLTEL 556
V T L +++ V VGDD G +S + ++ L + P + L+H E
Sbjct: 623 QAVVQKKKTKLTHITFNPNFPIVLVGDDRGYVSSLKLSPNLRKVPKDKKGAALNHG-PEA 681
Query: 557 QLASAD 574
++A D
Sbjct: 682 EIAKMD 687
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,816,970
Number of Sequences: 369166
Number of extensions: 2112137
Number of successful extensions: 6141
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5692
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6098
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6776504000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)