Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_I24
(629 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P06198|MYSP_SCHMA Paramyosin 126 5e-29
sp|Q05870|MYSP_SCHJA Paramyosin (Antigen Sj97) 126 5e-29
sp|P35417|MYSP_ECHGR Paramyosin 124 2e-28
sp|P35418|MYSP_TAESO Paramyosin (Antigen B) (AgB) 123 3e-28
sp|Q8T305|MYSP_TAESA Paramyosin 121 2e-27
sp|O96064|MYSP_MYTGA Paramyosin 112 8e-25
sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscle 108 1e-23
sp|P05661|MYSA_DROME Myosin heavy chain, muscle 102 6e-22
sp|P13535|MYH8_HUMAN Myosin-8 (Myosin heavy chain, skeletal... 102 1e-21
sp|P12882|MYH1_HUMAN Myosin-1 (Myosin heavy chain, skeletal... 100 3e-21
>sp|P06198|MYSP_SCHMA Paramyosin
Length = 866
Score = 126 bits (316), Expect = 5e-29
Identities = 65/136 (47%), Positives = 91/136 (66%)
Frame = +3
Query: 3 QEQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENER 182
QEQ N+K E RK L E+REI +LE E+S ++E ++ Q Q R+R+LE+E + E
Sbjct: 688 QEQGNYKHAEALRKQLEIEIREITVKLEEAEASATREGRRMVQKLQARVRELESEFDGES 747
Query: 183 VRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESAST 362
R KD RK ER +E+Q QA+DDRR V++LQ LLD K+K+YKRQL+E+E S
Sbjct: 748 RRCKDALAQARKFERQYKELQTQAEDDRRMVLELQDLLDKTQMKMKAYKRQLEEMEEVSQ 807
Query: 363 ENLNKYKRAQKLIDEA 410
+NKY++AQ+ I+EA
Sbjct: 808 ITMNKYRKAQQQIEEA 823
Score = 40.8 bits (94), Expect = 0.003
Identities = 26/135 (19%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = +3
Query: 9 QENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVR 188
+E ++ E+ RK + E+ + E E+ + + ++ I DLE +L+
Sbjct: 493 RERDEELESLRKSTTRTIEELTVTITEMEVKYKSELSRLKKRYESNIADLEIQLDTANKA 552
Query: 189 SKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTEN 368
+ ++ + + +++++ D++RR + L K +++E+ S + EN
Sbjct: 553 NANLMKENKNLSQRVKDLETFLDEERRLREAAENNLQITEHKRLQLANEIEEIRS-TLEN 611
Query: 369 LNKY-KRAQKLIDEA 410
L + K A+ ++EA
Sbjct: 612 LERLRKHAETELEEA 626
Score = 30.8 bits (68), Expect = 3.0
Identities = 30/152 (19%), Positives = 62/152 (40%), Gaps = 27/152 (17%)
Frame = +3
Query: 30 ETARKGLFSELREIKTRLESRESSTSKEIQKNTQI------FQERIRDLETE-------- 167
E + L E++++++ +ES S+ I++ Q R+ +L E
Sbjct: 331 EKLKTKLTLEIKDLQSEIESLSLENSELIRRAKAAESLASDLQRRVDELTIEVNTLTSQN 390
Query: 168 --LENERVRSKDVQNAI-----------RKQERSIREIQQQADDDRRTVIDLQQLLDAAN 308
LE+E +R K + N + R+ ++E++ D R + DL+ L
Sbjct: 391 SQLESENLRLKSLVNDLTDKNNLLERENRQMNDQVKELKSSLRDANRRLTDLEALRSQLE 450
Query: 309 GKIKSYKRQLDELESASTENLNKYKRAQKLID 404
+ + L + E A + KY+ +Q ++
Sbjct: 451 AERDNLASALHDAEEALHDMDQKYQASQAALN 482
Score = 29.3 bits (64), Expect = 8.7
Identities = 24/128 (18%), Positives = 59/128 (46%)
Frame = +3
Query: 30 ETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVRSKDVQNA 209
E ++ + E++ E RE + ++K I+DL++E+E+ + + ++
Sbjct: 303 EEMKRKFTMRITELEDTAE-RERLKAVSLEKLKTKLTLEIKDLQSEIESLSLENSELIRR 361
Query: 210 IRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTENLNKYKRA 389
+ E ++Q++ D+ V L + N +++S +L L + T+ N +R
Sbjct: 362 AKAAESLASDLQRRVDELTIEV----NTLTSQNSQLESENLRLKSLVNDLTDKNNLLERE 417
Query: 390 QKLIDEAV 413
+ +++ V
Sbjct: 418 NRQMNDQV 425
>sp|Q05870|MYSP_SCHJA Paramyosin (Antigen Sj97)
Length = 866
Score = 126 bits (316), Expect = 5e-29
Identities = 65/136 (47%), Positives = 90/136 (66%)
Frame = +3
Query: 3 QEQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENER 182
QEQEN+K E RK L E+REI +LE E+ ++E ++ Q Q R+R+LE E + E
Sbjct: 688 QEQENYKHAEALRKQLEIEIREITVKLEEAEAFATREGRRMVQKLQARVRELEAEFDGES 747
Query: 183 VRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESAST 362
R KD RK ER +E+Q QA+DDRR V++LQ LLD K+K+YKRQL+E+E S
Sbjct: 748 RRCKDALAQARKFERQYKELQTQAEDDRRMVLELQDLLDKTQMKMKAYKRQLEEMEEVSQ 807
Query: 363 ENLNKYKRAQKLIDEA 410
+NKY++AQ+ I+EA
Sbjct: 808 ITMNKYRKAQQQIEEA 823
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/126 (19%), Positives = 57/126 (45%)
Frame = +3
Query: 9 QENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVR 188
+E ++ E+ RK + E+ + E E+ + + ++ I DLE +L+
Sbjct: 493 RERDEELESLRKSTTRTIEELTVTITEMEVKYKSELSRLKKRYESSIADLEIQLDATNKA 552
Query: 189 SKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTEN 368
+ ++ + + +++++ DD+RR + L K +++EL SA EN
Sbjct: 553 NANLMKENKNLAQRVKDLETFLDDERRLREAAENNLQITEHKRIQLANEVEELRSA-MEN 611
Query: 369 LNKYKR 386
L + ++
Sbjct: 612 LERLRK 617
Score = 34.7 bits (78), Expect = 0.21
Identities = 33/142 (23%), Positives = 62/142 (43%), Gaps = 14/142 (9%)
Frame = +3
Query: 21 KKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETE---LENERVRS 191
K ++ + L E E+ R +S ES S E+Q+ + L ++ LE+E +R
Sbjct: 342 KDLQSEIESLSLENGELIRRAKSAESLAS-ELQRRVDELTIEVNTLTSQNNQLESENMRL 400
Query: 192 K-------DVQNAIRKQERS----IREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQL 338
K D NA+ ++ R ++E++ D R + DL+ L + + L
Sbjct: 401 KSLVNDLTDKNNALERENRQMNDQVKELKSSLRDANRRLTDLEALRSQLEAERDNLASAL 460
Query: 339 DELESASTENLNKYKRAQKLID 404
+ E A + KY+ +Q ++
Sbjct: 461 HDAEEALRDMDQKYQASQAALN 482
Score = 32.0 bits (71), Expect = 1.3
Identities = 31/137 (22%), Positives = 63/137 (45%)
Frame = +3
Query: 3 QEQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENER 182
+E E K+ T R +EL ++ R + S K K T I+DL++E+E+
Sbjct: 300 EEFEEMKRKLTMR---ITELEDVAERERLKAVSLEKLKTKLTL----EIKDLQSEIESLS 352
Query: 183 VRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESAST 362
+ + ++ + E E+Q++ D+ V L + N +++S +L L + T
Sbjct: 353 LENGELIRRAKSAESLASELQRRVDELTIEV----NTLTSQNNQLESENMRLKSLVNDLT 408
Query: 363 ENLNKYKRAQKLIDEAV 413
+ N +R + +++ V
Sbjct: 409 DKNNALERENRQMNDQV 425
>sp|P35417|MYSP_ECHGR Paramyosin
Length = 863
Score = 124 bits (312), Expect = 2e-28
Identities = 62/136 (45%), Positives = 94/136 (69%)
Frame = +3
Query: 3 QEQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENER 182
QEQEN+K+ ET RK L E+REI +LE E+ ++E ++ Q Q R+R+LE EL+ E
Sbjct: 684 QEQENYKRAETLRKQLEIEIREITVKLEEAEAFATREGRRMVQKLQNRVRELEAELDGEI 743
Query: 183 VRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESAST 362
R+K+ + RK ER +E+Q Q++DD+R +++LQ LLD K+K+YKRQL+E E S
Sbjct: 744 RRAKEAFASARKYERQFKELQTQSEDDKRMILELQDLLDKTQIKMKAYKRQLEEQEEVSQ 803
Query: 363 ENLNKYKRAQKLIDEA 410
++KY++AQ+ I+EA
Sbjct: 804 LTMSKYRKAQQQIEEA 819
Score = 36.6 bits (83), Expect = 0.054
Identities = 23/134 (17%), Positives = 59/134 (44%)
Frame = +3
Query: 9 QENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVR 188
+E ++ E RK + E+ T + E ++ + + ++ I +LE +L+
Sbjct: 489 REKDEELENLRKSTTRTIEELTTTISEMEVRFKSDMSRLKKKYEATISELEVQLDVANKA 548
Query: 189 SKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTEN 368
+ + + + ++E+Q +D+RR + L + K + +++E+ S +
Sbjct: 549 NASLNRENKALAQRVQELQTALEDERRAREAAESNLQVSERKRIALTSEVEEIRSQLELS 608
Query: 369 LNKYKRAQKLIDEA 410
K A+ +++A
Sbjct: 609 DRARKNAESELNDA 622
Score = 35.4 bits (80), Expect = 0.12
Identities = 23/98 (23%), Positives = 48/98 (48%)
Frame = +3
Query: 54 SELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVRSKDVQNAIRKQERSI 233
+++ +KTRLE + ++E ++ + RI +LE E+ER R+ +++ K I
Sbjct: 278 ADMAALKTRLERELMAKTEEFEELKRKLTVRITELEDIAEHERTRANNLEKTKVKLTIEI 337
Query: 234 REIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDEL 347
+++Q + + L A NG++ +Q + L
Sbjct: 338 KDLQAE-----------NEALAAENGELTHRAKQAENL 364
>sp|P35418|MYSP_TAESO Paramyosin (Antigen B) (AgB)
Length = 863
Score = 123 bits (309), Expect = 3e-28
Identities = 62/136 (45%), Positives = 93/136 (68%)
Frame = +3
Query: 3 QEQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENER 182
QEQEN+K+ ET RK L E+REI +LE E+ ++E ++ Q Q R+R+LE EL+ E
Sbjct: 684 QEQENYKRAETLRKQLEIEIREITVKLEEAEAFATREGRRMVQKLQNRVRELEAELDGEI 743
Query: 183 VRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESAST 362
R+K+ RK ER +E+Q Q++DD+R +++LQ LLD K+K+YKRQL+E E S
Sbjct: 744 RRAKEAFANARKYERQFKELQTQSEDDKRMILELQDLLDKTQIKMKAYKRQLEEQEEVSQ 803
Query: 363 ENLNKYKRAQKLIDEA 410
++KY++AQ+ I+EA
Sbjct: 804 LTMSKYRKAQQQIEEA 819
Score = 36.6 bits (83), Expect = 0.054
Identities = 23/134 (17%), Positives = 60/134 (44%)
Frame = +3
Query: 9 QENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVR 188
+E ++ E RK + E+ T + E ++ + + ++ I +LE +L+
Sbjct: 489 REKDEELENLRKSTTRTIEELTTTISEMEVRFKSDMSRLKKKYEATISELEVQLDVANKA 548
Query: 189 SKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTEN 368
+ ++ + + ++E+Q +D+RR + L + K + +++E+ S +
Sbjct: 549 NVNLNRENKTLAQRVQELQAALEDERRAREAAESNLQVSERKRIALASEVEEIRSQLELS 608
Query: 369 LNKYKRAQKLIDEA 410
K A+ +++A
Sbjct: 609 DRARKNAESELNDA 622
Score = 36.2 bits (82), Expect = 0.071
Identities = 23/98 (23%), Positives = 48/98 (48%)
Frame = +3
Query: 54 SELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVRSKDVQNAIRKQERSI 233
+++ +KTRLE + ++E ++ + RI +LE E+ER R+ +++ K I
Sbjct: 278 ADMAALKTRLERELMAKTEEFEELKRKLTVRITELEDMAEHERTRANNLEKTKVKLTLEI 337
Query: 234 REIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDEL 347
+++Q + + L A NG++ +Q + L
Sbjct: 338 KDLQAE-----------NEALAAENGELTHRAKQAENL 364
>sp|Q8T305|MYSP_TAESA Paramyosin
Length = 863
Score = 121 bits (303), Expect = 2e-27
Identities = 61/136 (44%), Positives = 92/136 (67%)
Frame = +3
Query: 3 QEQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENER 182
QEQEN+ + ET RK L E+REI +LE E+ ++E ++ Q Q R+R+LE EL+ E
Sbjct: 684 QEQENYXRAETLRKQLEIEIREITVKLEEAEAFATREGRRMVQKLQNRVRELEAELDGEI 743
Query: 183 VRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESAST 362
R+K+ RK ER +E+Q Q++DD+R +++LQ LLD K+K+YKRQL+E E S
Sbjct: 744 RRAKEAFANARKYERQFKELQTQSEDDKRMILELQDLLDKTQIKMKAYKRQLEEQEEVSQ 803
Query: 363 ENLNKYKRAQKLIDEA 410
++KY++AQ+ I+EA
Sbjct: 804 LTMSKYRKAQQQIEEA 819
Score = 37.0 bits (84), Expect = 0.042
Identities = 22/98 (22%), Positives = 49/98 (50%)
Frame = +3
Query: 54 SELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVRSKDVQNAIRKQERSI 233
+++ +KTRLE + ++E ++ + RI +LE E+ER R+ +++ K I
Sbjct: 278 ADMAALKTRLERELMAKTEEFEELKRKLTVRITELEDMAEHERTRANNLEKTKVKLTLEI 337
Query: 234 REIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDEL 347
+++Q + + +L + A +R++DE+
Sbjct: 338 KDLQAENEALAAENGELTHRVKQAENLANELQRRIDEM 375
Score = 37.0 bits (84), Expect = 0.042
Identities = 23/134 (17%), Positives = 60/134 (44%)
Frame = +3
Query: 9 QENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVR 188
+E ++ E RK + E+ T + E ++ + + ++ I +LE +L+
Sbjct: 489 REKDEELENLRKSTTRTIEELTTTISEMEVRFKSDMSRLKKKYEATISELEVQLDVANKA 548
Query: 189 SKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTEN 368
+ ++ + + ++E+Q +D+RR + L + K + +++E+ S +
Sbjct: 549 NANLNRENKTLAQRVQELQAALEDERRAREAAESNLQVSERKRIALASEVEEIRSQLELS 608
Query: 369 LNKYKRAQKLIDEA 410
K A+ +++A
Sbjct: 609 DRARKNAESELNDA 622
Score = 30.0 bits (66), Expect = 5.1
Identities = 24/117 (20%), Positives = 53/117 (45%), Gaps = 4/117 (3%)
Frame = +3
Query: 30 ETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVRSKDVQNA 209
E ++ L + E++ E E + + ++K I+DL+ E E + ++ +
Sbjct: 299 EELKRKLTVRITELEDMAE-HERTRANNLEKTKVKLTLEIKDLQAENEALAAENGELTHR 357
Query: 210 IRKQERSIREIQQQADD---DRRTVIDLQQLLDAANGKIKSYKRQL-DELESASTEN 368
+++ E E+Q++ D+ + T+ L+A N ++K L D + + EN
Sbjct: 358 VKQAENLANELQRRIDEMTVEINTLNSANSALEADNMRLKGQVGDLTDRIANLDREN 414
>sp|O96064|MYSP_MYTGA Paramyosin
Length = 864
Score = 112 bits (280), Expect = 8e-25
Identities = 59/136 (43%), Positives = 85/136 (62%)
Frame = +3
Query: 3 QEQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENER 182
QEQ+N+K E+ RK L E+REI RLE E+ +E ++ Q RIRDLE ELE ++
Sbjct: 697 QEQDNYKNAESLRKQLEIEIREITVRLEEAEAFAQREGKRQIAKLQARIRDLENELEADQ 756
Query: 183 VRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESAST 362
R ++ + RK ER +E Q +D+DRR V +L + D K K+YKR ++E E ++
Sbjct: 757 RRLREAAASARKFERQWKETVQASDEDRRQVAELTSITDQLTMKCKTYKRMIEEAEDVAS 816
Query: 363 ENLNKYKRAQKLIDEA 410
+NKY++AQ LIDEA
Sbjct: 817 ITMNKYRKAQSLIDEA 832
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/133 (20%), Positives = 61/133 (45%)
Frame = +3
Query: 9 QENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVR 188
+E ++ ++ RK + E++ L E+ EI + + ++ IR+LE L+N
Sbjct: 502 REKDEEIDSIRKSSARAIDELQRTLVEVETRYKTEISRIKKKYETDIRELEGALDNANRA 561
Query: 189 SKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTEN 368
+ + I+ + RE++ Q ++ R + D + L + K + +++L++ S
Sbjct: 562 NAEYLKQIKSLQNRNRELELQLEEATRQLDDTRNQLSVSERKRITIQQELEDARSLLEHA 621
Query: 369 LNKYKRAQKLIDE 407
K A+ + E
Sbjct: 622 ERARKNAENELGE 634
Score = 35.0 bits (79), Expect = 0.16
Identities = 24/125 (19%), Positives = 55/125 (44%)
Frame = +3
Query: 3 QEQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENER 182
+E EN L + +KT+ + + +E+++ + +I++LE E R
Sbjct: 274 EESENASSLRAQLSSLSATYAALKTKYDKELMAKQEELEEIRRRLSIKIQELEDTCEQLR 333
Query: 183 VRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESAST 362
R ++ K IREI + ++ + V DL + + + +++ D+L + +
Sbjct: 334 TRCNTLEKTKNKLTVEIREITIELENTQIIVQDLTKRNRQLENENAALQKRCDDLSAENG 393
Query: 363 ENLNK 377
+ N+
Sbjct: 394 QLRNE 398
>sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscle
Length = 1938
Score = 108 bits (270), Expect = 1e-23
Identities = 54/135 (40%), Positives = 89/135 (65%)
Frame = +3
Query: 6 EQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERV 185
EQ++ + E RK L S+++E + RL+ E+S+ K +K Q + R+ +LE EL+NE+
Sbjct: 1769 EQDHSNQVEKVRKNLESQVKEFQIRLDEAEASSLKGGKKMIQKLESRVHELEAELDNEQR 1828
Query: 186 RSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTE 365
R + Q +RK +R ++E+ QAD+DR+ LQ+L+D N KIK++KRQ++E E +
Sbjct: 1829 RHAETQKNMRKADRRLKELAFQADEDRKNQERLQELIDKLNAKIKTFKRQVEEAEEIAAI 1888
Query: 366 NLNKYKRAQKLIDEA 410
NL KY++AQ ++EA
Sbjct: 1889 NLAKYRKAQHELEEA 1903
Score = 49.7 bits (117), Expect = 6e-06
Identities = 33/139 (23%), Positives = 71/139 (51%), Gaps = 11/139 (7%)
Frame = +3
Query: 3 QEQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQ----------KNTQIFQERIR 152
Q + + + E +++ + +EL+ K+RL++ S +++++ K ++
Sbjct: 1252 QMSDLNARLEDSQRSI-NELQSQKSRLQAENSDLTRQLEDAEHRVSVLSKEKSQLSSQLE 1310
Query: 153 DLETELENE-RVRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYK 329
D LE E R RSK +QN +R + I++Q ++++ + D+Q+ L AN +I+ ++
Sbjct: 1311 DARRSLEEETRARSK-LQNEVRNMHADMDAIREQLEEEQESKSDVQRQLSKANNEIQQWR 1369
Query: 330 RQLDELESASTENLNKYKR 386
+ + + TE L KR
Sbjct: 1370 SKFESEGANRTEELEDQKR 1388
Score = 46.2 bits (108), Expect = 7e-05
Identities = 35/134 (26%), Positives = 65/134 (48%)
Frame = +3
Query: 6 EQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERV 185
E+ K E R L EL E+ RL+ +TS +I+ N + E ++ + +LE +
Sbjct: 1122 ERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELLK-IRRDLEEASL 1180
Query: 186 RSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTE 365
+ + +A+RK+ Q A++ V LQ++ K KR++D+LES T
Sbjct: 1181 QHEAQISALRKKH------QDAANEMADQVDQLQKVKSKLEKDKKDLKREMDDLESQMTH 1234
Query: 366 NLNKYKRAQKLIDE 407
N+ ++K++ +
Sbjct: 1235 NMKNKGCSEKVMKQ 1248
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/133 (23%), Positives = 64/133 (48%), Gaps = 4/133 (3%)
Frame = +3
Query: 9 QENHKKCETARK---GLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELEN- 176
Q KC K L L E++ LE RE +++K + ++ ++ + +E+
Sbjct: 1008 QAEEDKCNHLNKLKAKLEQALDELEDNLE-REKKVRGDVEKAKRKVEQDLKSTQENVEDL 1066
Query: 177 ERVRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESA 356
ERV+ ++++ +R++E I + + +D++ V LQ+ KIK + +++ELE
Sbjct: 1067 ERVK-RELEENVRRKEAEISSLNSKLEDEQNLVSQLQR-------KIKELQARIEELEEE 1118
Query: 357 STENLNKYKRAQK 395
N + +K
Sbjct: 1119 LEAERNARAKVEK 1131
Score = 35.8 bits (81), Expect = 0.093
Identities = 35/142 (24%), Positives = 70/142 (49%), Gaps = 17/142 (11%)
Frame = +3
Query: 21 KKCETARKGLFSELREIKTRLESRESSTSK---EIQKNTQIFQERIRDLETELENERVRS 191
++ E ++ L + L E + LE E+ + EI +RI++ E E +N R
Sbjct: 1528 RRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTR--- 1584
Query: 192 KDVQNAIRKQERSIR-EIQQQADDDR------RTVIDLQQLLDAAN-GK------IKSYK 329
++ Q A+ + S+ E + +AD R + + +L+ LDA+N GK +K Y+
Sbjct: 1585 RNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQ 1644
Query: 330 RQLDELESASTENLNKYKRAQK 395
+Q+ E++++ E + A++
Sbjct: 1645 QQIREMQTSIEEEQRQRDEARE 1666
>sp|P05661|MYSA_DROME Myosin heavy chain, muscle
Length = 1962
Score = 102 bits (255), Expect = 6e-22
Identities = 50/135 (37%), Positives = 88/135 (65%)
Frame = +3
Query: 6 EQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERV 185
EQ++ + E RK L +++E++ RL+ E++ K +K Q ++R+R+LE EL+ E+
Sbjct: 1771 EQDHAQTQEKLRKALEQQIKELQVRLDEAEANALKGGKKAIQKLEQRVRELENELDGEQR 1830
Query: 186 RSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTE 365
R D Q +RK ER ++E+ Q+++DR+ +Q L+D KIK+YKRQ++E E +
Sbjct: 1831 RHADAQKNLRKSERRVKELSFQSEEDRKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAAL 1890
Query: 366 NLNKYKRAQKLIDEA 410
NL K+++AQ+ ++EA
Sbjct: 1891 NLAKFRKAQQELEEA 1905
>sp|P13535|MYH8_HUMAN Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)
(MyHC-perinatal)
Length = 1937
Score = 102 bits (253), Expect = 1e-21
Identities = 49/136 (36%), Positives = 83/136 (61%)
Frame = +3
Query: 3 QEQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENER 182
+EQ+ E +K L +++++ RL+ E K +K Q + R+R+LE E+ENE+
Sbjct: 1774 KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQ 1833
Query: 183 VRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESAST 362
R+ + +RK ER ++E+ Q ++DR+ V+ LQ L+D K+KSYKRQ +E E S
Sbjct: 1834 KRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1893
Query: 363 ENLNKYKRAQKLIDEA 410
NL+K+++ Q ++EA
Sbjct: 1894 ANLSKFRKLQHELEEA 1909
Score = 37.4 bits (85), Expect = 0.032
Identities = 32/145 (22%), Positives = 67/145 (46%), Gaps = 14/145 (9%)
Frame = +3
Query: 21 KKCETARKGLFSELREIKTRLESRES------STSKEIQKNTQIFQERIRDLETELENER 182
++ E +RK EL + R++ + +T K+++ + Q + ++ E N
Sbjct: 1696 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAE 1755
Query: 183 VRSKD-------VQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANG-KIKSYKRQL 338
++K + ++K++ + +++ + +TV DLQ LD A +K K+Q+
Sbjct: 1756 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQI 1815
Query: 339 DELESASTENLNKYKRAQKLIDEAV 413
+LE+ E + + QK EAV
Sbjct: 1816 QKLEARVRELEGEVENEQKRNAEAV 1840
Score = 35.0 bits (79), Expect = 0.16
Identities = 41/184 (22%), Positives = 70/184 (38%), Gaps = 56/184 (30%)
Frame = +3
Query: 6 EQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQI---FQERIRDLET---- 164
E+ + K E R L EL EI RLE +TS +++ N + FQ+ RDLE
Sbjct: 1128 ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQ 1187
Query: 165 ---------------------ELEN-ERVRSK---------------------------D 197
+++N +RV+ K +
Sbjct: 1188 HEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGN 1247
Query: 198 VQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTENLNK 377
++ R E + E++ + ++ +R + DL + Y RQLDE + A L++
Sbjct: 1248 LEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDE-KDALVSQLSR 1306
Query: 378 YKRA 389
K+A
Sbjct: 1307 SKQA 1310
Score = 32.3 bits (72), Expect = 1.0
Identities = 31/150 (20%), Positives = 63/150 (42%), Gaps = 14/150 (9%)
Frame = +3
Query: 3 QEQENH-----KKC---ETARKGLFSELREIKTRLESRESSTS------KEIQKNTQIFQ 140
QE E H KC E ++ L +E+ ++ +E ++ + + K ++
Sbjct: 1401 QEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWK 1460
Query: 141 ERIRDLETELENERVRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIK 320
++ + + ELE + S+ + + K + E Q + RR +LQQ + +I
Sbjct: 1461 QKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIA 1520
Query: 321 SYKRQLDELESASTENLNKYKRAQKLIDEA 410
+Q+ ELE + + Q ++EA
Sbjct: 1521 EGGKQIHELEKIKKQVEQEKCEIQAALEEA 1550
Score = 31.6 bits (70), Expect = 1.7
Identities = 20/96 (20%), Positives = 42/96 (43%)
Frame = +3
Query: 57 ELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVRSKDVQNAIRKQERSIR 236
E+ + +++E E + ++QK + Q RI +L E+E ER + R +
Sbjct: 1089 EISNLISKIED-EQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELE 1147
Query: 237 EIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDE 344
EI ++ ++ +L + + +R L+E
Sbjct: 1148 EISERLEEAGGATSAQVELNKKREAEFQKLRRDLEE 1183
>sp|P12882|MYH1_HUMAN Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy
chain IIx/d) (MyHC-IIx/d)
Length = 1939
Score = 100 bits (249), Expect = 3e-21
Identities = 48/136 (35%), Positives = 83/136 (61%)
Frame = +3
Query: 3 QEQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENER 182
+EQ+ E +K L +++++ RL+ E K +K Q + R+R+LE E+E+E+
Sbjct: 1775 KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1834
Query: 183 VRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESAST 362
R+ + +RK ER ++E+ Q ++DR+ ++ LQ L+D K+KSYKRQ +E E S
Sbjct: 1835 KRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1894
Query: 363 ENLNKYKRAQKLIDEA 410
NL+K++R Q ++EA
Sbjct: 1895 VNLSKFRRIQHELEEA 1910
Score = 36.2 bits (82), Expect = 0.071
Identities = 30/136 (22%), Positives = 56/136 (41%), Gaps = 2/136 (1%)
Frame = +3
Query: 3 QEQENHKKCETARKGLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENER 182
Q E KK E GL S++ + E + ++QK + Q RI +LE E+E ER
Sbjct: 1079 QLDEKLKKKEFEMSGLQSKIED--------EQALGMQLQKKIKELQARIEELEEEIEAER 1130
Query: 183 VRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDE--LESA 356
+ R + EI ++ ++ ++ + + +R L+E L+
Sbjct: 1131 ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHE 1190
Query: 357 STENLNKYKRAQKLID 404
+T + K A + +
Sbjct: 1191 ATAATLRKKHADSVAE 1206
Score = 34.7 bits (78), Expect = 0.21
Identities = 26/110 (23%), Positives = 50/110 (45%)
Frame = +3
Query: 60 LREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVRSKDVQNAIRKQERSIRE 239
L+ +K +LE +S EI DL + +E +++ R E + E
Sbjct: 1214 LQRVKQKLEKEKSEMKMEID-----------DLASNMETVSKAKGNLEKMCRALEDQLSE 1262
Query: 240 IQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTENLNKYKRA 389
I+ + ++ +R + DL + Y RQLDE ++ ++ L++ K+A
Sbjct: 1263 IKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQ-LSRGKQA 1311
Score = 30.8 bits (68), Expect = 3.0
Identities = 30/130 (23%), Positives = 62/130 (47%), Gaps = 10/130 (7%)
Frame = +3
Query: 36 ARKGLFSELREIKTRLESR--ESSTSKEIQKNTQIFQERI-RDLETELENERVRSKDVQN 206
A + + L + K +LE + + S E +K ++ ER R LE +L+ + + D++N
Sbjct: 1016 AEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIEN 1075
Query: 207 -------AIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELESASTE 365
++K+E + +Q + +D++ + LQ+ KIK + +++ELE
Sbjct: 1076 DKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQK-------KIKELQARIEELEEEIEA 1128
Query: 366 NLNKYKRAQK 395
+A+K
Sbjct: 1129 ERASRAKAEK 1138
Score = 29.6 bits (65), Expect = 6.6
Identities = 24/119 (20%), Positives = 50/119 (42%), Gaps = 9/119 (7%)
Frame = +3
Query: 21 KKCETARK--GLFSELREIKTRLESRESSTSKEIQKNTQIFQERIRDLETELENERVRSK 194
K ET ++ + E + K L E+ + +K + QE+ DL+ +++ E
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEK-NDLQLQVQAEADSLA 903
Query: 195 DVQNAIRKQ-------ERSIREIQQQADDDRRTVIDLQQLLDAANGKIKSYKRQLDELE 350
D + + E I+E+ ++A+D+ +L + K+ +D+LE
Sbjct: 904 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Score = 29.3 bits (64), Expect = 8.7
Identities = 28/150 (18%), Positives = 63/150 (42%), Gaps = 14/150 (9%)
Frame = +3
Query: 3 QEQENH-----KKC---ETARKGLFSELREIKTRLESRESSTS------KEIQKNTQIFQ 140
Q+ E H KC E ++ L +E+ ++ +E ++ + + K ++
Sbjct: 1402 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWK 1461
Query: 141 ERIRDLETELENERVRSKDVQNAIRKQERSIREIQQQADDDRRTVIDLQQLLDAANGKIK 320
++ + ELE + S+ + + K + + E Q + +R +LQQ + +I
Sbjct: 1462 QKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1521
Query: 321 SYKRQLDELESASTENLNKYKRAQKLIDEA 410
+++ ELE + + Q ++EA
Sbjct: 1522 EGGKRIHELEKIKKQVEQEKSELQAALEEA 1551
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,520,885
Number of Sequences: 369166
Number of extensions: 940842
Number of successful extensions: 4935
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4017
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4795
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5023626210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)