Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_I04
(835 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P48060|GLIP1_HUMAN Glioma pathogenesis-related protein 1... 138 2e-32
sp|P60623|CRVP_TRIST Cysteine-rich secretory protein precur... 132 1e-30
sp|Q9CWG1|GLIP1_MOUSE Glioma pathogenesis-related protein 1... 129 1e-29
sp|O19010|CRIS3_HORSE Cysteine-rich secretory protein 3 pre... 127 4e-29
sp|Q8JI39|CRVP_TRIFL Triflin precursor 124 4e-28
sp|Q7ZZN9|CRVP_TRIJE Cysteine-rich venom protein precursor ... 123 7e-28
sp|Q8JGT9|CRVP_RHATT Tigrin precursor 122 2e-27
sp|Q8JI40|CRVP_AGKHA Ablomin precursor 122 2e-27
sp|Q8AVA4|CRVP_PSEAU Pseudechetoxin precursor (PsTx) 121 2e-27
sp|P79845|CRVP_TRIMU Cysteine-rich venom protein precursor ... 120 6e-27
>sp|P48060|GLIP1_HUMAN Glioma pathogenesis-related protein 1 precursor (GliPR 1) (RTVP-1
protein)
Length = 266
Score = 138 bits (348), Expect = 2e-32
Identities = 80/204 (39%), Positives = 113/204 (55%), Gaps = 14/204 (6%)
Frame = +2
Query: 17 IVSFIS-IALTFSTPP--EYKDFL---LKAHNDLRRDVALGKTPNQPGAANMIEMVWDDA 178
+VSF+S + T + P E +DF+ ++ HN R +V +P A++M+ M WD A
Sbjct: 11 MVSFVSNYSHTANILPDIENEDFIKDCVRIHNKFRSEV-------KPTASDMLYMTWDPA 63
Query: 179 LAGKAEEWAGKCIAGHDTY---DDRQLDKFMFVGQNMFAGS----NYKEVVQGWYDEYKD 337
LA A+ WA C H+T + F +G+N++ GS + + WYDE +D
Sbjct: 64 LAQIAKAWASNCQFSHNTRLKPPHKLHPNFTSLGENIWTGSVPIFSVSSAITNWYDEIQD 123
Query: 338 YTYEGKGCSAVCGHYTQVAWAKSYAVGCAAVNCKEKTG-GSFAYGWLFICNYGPAGNFND 514
Y ++ + C VCGHYTQV WA SY VGCA C + +G + + G FICNYGP GN+
Sbjct: 124 YDFKTRICKKVCGHYTQVVWADSYKVGCAVQFCPKVSGFDALSNGAHFICNYGPGGNY-P 182
Query: 515 EAPYEVGAACSKCPKGTSCKNNLC 586
PY+ GA CS CP C +NLC
Sbjct: 183 TWPYKRGATCSACPNNDKCLDNLC 206
>sp|P60623|CRVP_TRIST Cysteine-rich secretory protein precursor (Stecrisp)
Length = 233
Score = 132 bits (332), Expect = 1e-30
Identities = 71/184 (38%), Positives = 97/184 (52%), Gaps = 8/184 (4%)
Frame = +2
Query: 59 PEYKDFLLKAHNDLRRDVALGKTPNQPGAANMIEMVWDDALAGKAEEWAGKCIAGHDTYD 238
PE ++ ++ HN LRR V P A+NM+ M W A AE WA +CI H +Y+
Sbjct: 24 PEIQNEIVDLHNSLRRSV-------NPTASNMLRMEWYPEAADNAERWAYRCIESHSSYE 76
Query: 239 DRQLDKFMFVGQNMFAGS---NYKEVVQGWYDEYKDYTYEGKGC---SAVCGHYTQVAWA 400
R ++ G+N++ + +++ W+DEYKD+ Y G G +AV GHYTQ+ W
Sbjct: 77 SRVIEGIK-CGENIYMSPYPMKWTDIIHAWHDEYKDFKY-GVGADPPNAVTGHYTQIVWY 134
Query: 401 KSYAVGCAAVNCKEKTGGSFAYGWLFICNYGPAGNF--NDEAPYEVGAACSKCPKGTSCK 574
KSY +GCAA C S Y + F+C Y PAGNF PY G C CP + C
Sbjct: 135 KSYRIGCAAAYCP-----SSPYSYFFVCQYCPAGNFIGKTATPYTSGTPCGDCP--SDCD 187
Query: 575 NNLC 586
N LC
Sbjct: 188 NGLC 191
>sp|Q9CWG1|GLIP1_MOUSE Glioma pathogenesis-related protein 1 precursor (GliPR 1)
Length = 255
Score = 129 bits (323), Expect = 1e-29
Identities = 77/198 (38%), Positives = 101/198 (51%), Gaps = 10/198 (5%)
Frame = +2
Query: 23 SFISIALTFSTPPEY--KDFL---LKAHNDLRRDVALGKTPNQPGAANMIEMVWDDALAG 187
S S + T ST P+ +DF+ ++ HN LR V+ P A NM+ M WD LA
Sbjct: 14 SVSSSSFTASTLPDITNEDFIKECVQVHNQLRSKVS-------PPARNMLYMSWDPKLAQ 66
Query: 188 KAEEWAGKCIAGHDTY-DDRQLDKFMFVGQNMFAGS----NYKEVVQGWYDEYKDYTYEG 352
A+ W C H+ R F +G+N++ GS + + WY+E K Y +
Sbjct: 67 IAKAWTKSCEFKHNPQLHSRIHPNFTALGENIWLGSLSIFSVSSAISAWYEEIKHYDFST 126
Query: 353 KGCSAVCGHYTQVAWAKSYAVGCAAVNCKEKTGGSFAYGWLFICNYGPAGNFNDEAPYEV 532
+ C VCGHYTQV WA SY +GCA C G FIC+YGPAGN+ PY+
Sbjct: 127 RKCRHVCGHYTQVVWADSYKLGCAVQLCPN--------GANFICDYGPAGNY-PTWPYKQ 177
Query: 533 GAACSKCPKGTSCKNNLC 586
GA CS CPK C N+LC
Sbjct: 178 GATCSDCPKDDKCLNSLC 195
>sp|O19010|CRIS3_HORSE Cysteine-rich secretory protein 3 precursor (CRISP-3)
Length = 245
Score = 127 bits (319), Expect = 4e-29
Identities = 71/185 (38%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Frame = +2
Query: 53 TPPEYKDFLLKAHNDLRRDVALGKTPNQPGAANMIEMVWDDALAGKAEEWAGKCIAGHDT 232
T E + ++ HNDLRR V+ P A+NM++M WD A A+ WA KC+ H
Sbjct: 33 TKSEVQKEIVNKHNDLRRTVS-------PLASNMLKMQWDSKTATNAQNWANKCLLQHSK 85
Query: 233 YDDRQLDKFMFVGQNMFAGS---NYKEVVQGWYDEYKDYTY--EGKGCSAVCGHYTQVAW 397
+DR + M G+N+F S ++ + +Q W+DE D+ Y K +AV GHYTQV W
Sbjct: 86 AEDRAVGT-MKCGENLFMSSIPNSWSDAIQNWHDEVHDFKYGVGPKTPNAVVGHYTQVVW 144
Query: 398 AKSYAVGCAAVNCKEKTGGSFAYGWLFICNYGPAGNFNDE--APYEVGAACSKCPKGTSC 571
SY VGC C ++ G+ Y ++C Y PAGN+ ++ PYE G C++CP +C
Sbjct: 145 YSSYRVGCGIAYCPKQ--GTLKY--YYVCQYCPAGNYVNKINTPYEQGTPCARCP--GNC 198
Query: 572 KNNLC 586
N LC
Sbjct: 199 DNGLC 203
>sp|Q8JI39|CRVP_TRIFL Triflin precursor
Length = 240
Score = 124 bits (310), Expect = 4e-28
Identities = 68/184 (36%), Positives = 94/184 (51%), Gaps = 8/184 (4%)
Frame = +2
Query: 59 PEYKDFLLKAHNDLRRDVALGKTPNQPGAANMIEMVWDDALAGKAEEWAGKCIAGHDTYD 238
PE ++ ++ HN LRR V P A+NM++M W A AE WA +CI H + D
Sbjct: 31 PEIQNEIIDLHNSLRRSV-------NPTASNMLKMEWYPEAAANAERWAYRCIESHSSRD 83
Query: 239 DRQLDKFMFVGQNMFAGS---NYKEVVQGWYDEYKDYTYEGKGC---SAVCGHYTQVAWA 400
R + G+N++ + + +++ W+ EYKD+ Y G G AV GHYTQ+ W
Sbjct: 84 SRVIGGIK-CGENIYMATYPAKWTDIIHAWHGEYKDFKY-GVGAVPSDAVIGHYTQIVWY 141
Query: 401 KSYAVGCAAVNCKEKTGGSFAYGWLFICNYGPAGNF--NDEAPYEVGAACSKCPKGTSCK 574
KSY GCAA C S Y + ++C Y PAGN PY+ G C CP + C
Sbjct: 142 KSYRAGCAAAYCP-----SSKYSYFYVCQYCPAGNIIGKTATPYKSGPPCGDCP--SDCD 194
Query: 575 NNLC 586
N LC
Sbjct: 195 NGLC 198
>sp|Q7ZZN9|CRVP_TRIJE Cysteine-rich venom protein precursor (TJ-CRVP)
Length = 240
Score = 123 bits (308), Expect = 7e-28
Identities = 68/184 (36%), Positives = 93/184 (50%), Gaps = 8/184 (4%)
Frame = +2
Query: 59 PEYKDFLLKAHNDLRRDVALGKTPNQPGAANMIEMVWDDALAGKAEEWAGKCIAGHDTYD 238
PE ++ ++ HN LRR V P A+NM++M W A AE WA CI H + D
Sbjct: 31 PEIQNEIIDLHNSLRRSV-------NPTASNMLKMEWYPEAAANAERWAYGCIESHSSRD 83
Query: 239 DRQLDKFMFVGQNMFAGS---NYKEVVQGWYDEYKDYTYEGKGC---SAVCGHYTQVAWA 400
R ++ G+N++ + +++ W+ EYKD+ Y G G AV GHYTQ+ W
Sbjct: 84 SRVIEGIK-CGENIYMSPYPMKWTDIIHAWHGEYKDFKY-GVGAVPSDAVVGHYTQIVWY 141
Query: 401 KSYAVGCAAVNCKEKTGGSFAYGWLFICNYGPAGNF--NDEAPYEVGAACSKCPKGTSCK 574
KSY +GCAA C S Y + ++C Y PAGN PY G C CP + C
Sbjct: 142 KSYRIGCAAAYCP-----SAEYSYFYVCQYCPAGNMIGKTATPYTSGPPCGDCP--SDCD 194
Query: 575 NNLC 586
N LC
Sbjct: 195 NGLC 198
>sp|Q8JGT9|CRVP_RHATT Tigrin precursor
Length = 237
Score = 122 bits (305), Expect = 2e-27
Identities = 71/198 (35%), Positives = 101/198 (51%), Gaps = 10/198 (5%)
Frame = +2
Query: 23 SFISIALTFSTP--PEYKDFLLKAHNDLRRDVALGKTPNQPGAANMIEMVWDDALAGKAE 196
SF ++ +P P + ++ HN RR V +P A NM++M W A AE
Sbjct: 16 SFGNVDFNSESPRNPGKQQEIVNIHNSFRRSV-------RPTARNMLKMEWYSEAASNAE 68
Query: 197 EWAGKCIAGHDTYDDRQLDKFMFVGQNMFAGSN---YKEVVQGWYDEYKDYTYEGKGCS- 364
WA +C H R L+ G+N+F S+ + ++Q WYDEY+++ Y G G +
Sbjct: 69 RWAYQCAYDHSPRSSRILNGIQ-CGENIFMASDPWAWTSIIQDWYDEYRNFVY-GVGANP 126
Query: 365 --AVCGHYTQVAWAKSYAVGCAAVNCKEKTGGSFAYGWLFICNYGPAGNF--NDEAPYEV 532
+V GHYTQ+ W KSY VGCAA C S Y + ++C Y PAGN + PY
Sbjct: 127 PDSVTGHYTQIVWYKSYLVGCAAAYCP-----SSLYNYFYVCQYCPAGNIQGSTSTPYAS 181
Query: 533 GAACSKCPKGTSCKNNLC 586
G C+ CP ++C N LC
Sbjct: 182 GPTCADCP--SNCDNGLC 197
>sp|Q8JI40|CRVP_AGKHA Ablomin precursor
Length = 240
Score = 122 bits (305), Expect = 2e-27
Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 8/184 (4%)
Frame = +2
Query: 59 PEYKDFLLKAHNDLRRDVALGKTPNQPGAANMIEMVWDDALAGKAEEWAGKCIAGHDTYD 238
PE ++ ++ HN LRR V P A+NM++M W A AE WA +CI H + D
Sbjct: 31 PEIQNEIVDLHNSLRRSV-------NPTASNMLKMEWYPEAAANAERWAYRCIEDHSSPD 83
Query: 239 DRQLDKFMFVGQNMFAGS---NYKEVVQGWYDEYKDYTYEGKGC---SAVCGHYTQVAWA 400
R L+ G+N++ + +++ W+DEYK++ Y G G +AV GH+TQ+ W
Sbjct: 84 SRVLEGIK-CGENIYMSPIPMKWTDIIHIWHDEYKNFKY-GIGADPPNAVSGHFTQIVWY 141
Query: 401 KSYAVGCAAVNCKEKTGGSFAYGWLFICNYGPAGNFNDE--APYEVGAACSKCPKGTSCK 574
KSY GCAA C S Y + ++C Y PAGN + PY G C CP ++C
Sbjct: 142 KSYRAGCAAAYCP-----SSEYSYFYVCQYCPAGNMRGKTATPYTSGPPCGDCP--SACD 194
Query: 575 NNLC 586
N LC
Sbjct: 195 NGLC 198
>sp|Q8AVA4|CRVP_PSEAU Pseudechetoxin precursor (PsTx)
Length = 238
Score = 121 bits (304), Expect = 2e-27
Identities = 68/186 (36%), Positives = 94/186 (50%), Gaps = 7/186 (3%)
Frame = +2
Query: 50 STPPEYKDFLLKAHNDLRRDVALGKTPNQPGAANMIEMVWDDALAGKAEEWAGKCIAGHD 229
S Y+ ++ HN LRR V +P A NM++M W+ A A+ WA +C H
Sbjct: 28 SNKKNYQKEIVDKHNALRRSV-------KPTARNMLQMKWNSRAAQNAKRWANRCTFAHS 80
Query: 230 TYDDRQLDKFMFVGQNMFAGSN---YKEVVQGWYDEYKDYTYE--GKGCSAVCGHYTQVA 394
+ R + K G+N+F S + VVQ WYDE K++ Y K +V GHYTQV
Sbjct: 81 PPNKRTVGKLR-CGENIFMSSQPFPWSGVVQAWYDEIKNFVYGIGAKPPGSVIGHYTQVV 139
Query: 395 WAKSYAVGCAAVNCKEKTGGSFAYGWLFICNYGPAGNFNDE--APYEVGAACSKCPKGTS 568
W KSY +GCA+ C +L++C Y PAGN PY+ G C+ CP ++
Sbjct: 140 WYKSYLIGCASAKCSSSK-------YLYVCQYCPAGNIRGSIATPYKSGPPCADCP--SA 190
Query: 569 CKNNLC 586
C N LC
Sbjct: 191 CVNKLC 196
>sp|P79845|CRVP_TRIMU Cysteine-rich venom protein precursor (TM-CRVP)
Length = 240
Score = 120 bits (300), Expect = 6e-27
Identities = 67/184 (36%), Positives = 93/184 (50%), Gaps = 8/184 (4%)
Frame = +2
Query: 59 PEYKDFLLKAHNDLRRDVALGKTPNQPGAANMIEMVWDDALAGKAEEWAGKCIAGHDTYD 238
PE ++ ++ HN LRR V P A+NM++M W A AE WA +CI H + D
Sbjct: 31 PEIQNEIIDLHNSLRRSV-------NPTASNMLKMEWYPEAAANAERWAYRCIESHSSRD 83
Query: 239 DRQLDKFMFVGQNMFAG---SNYKEVVQGWYDEYKDYTYEGKGC---SAVCGHYTQVAWA 400
R + G+N++ + + +++ W+ EYKD+ Y G G +A GHYTQ+ W
Sbjct: 84 SRVIGGIK-CGENIYMSPYPAKWTDIIHAWHGEYKDFKY-GVGAVPSNAATGHYTQIVWY 141
Query: 401 KSYAVGCAAVNCKEKTGGSFAYGWLFICNYGPAGNF--NDEAPYEVGAACSKCPKGTSCK 574
KSY GCAA C S Y + ++C Y PAGN PY G C CP + C
Sbjct: 142 KSYRGGCAAAYCP-----SSKYRYFYVCQYCPAGNMIGKTATPYTSGPPCGDCP--SDCD 194
Query: 575 NNLC 586
N LC
Sbjct: 195 NGLC 198
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,695,803
Number of Sequences: 369166
Number of extensions: 1872519
Number of successful extensions: 6051
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5673
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5843
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8100769320
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)