Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_H11
(617 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P20338|RAB4A_HUMAN Ras-related protein Rab-4A 110 3e-24
sp|Q6PHI9|RAB4A_BRARE Ras-related protein Rab-4A 110 4e-24
sp|Q68EK7|RAB4B_BRARE Ras-related protein Rab-4B 109 5e-24
sp|P05714|RAB4A_RAT Ras-related protein Rab-4A 109 6e-24
sp|P56371|RAB4A_MOUSE Ras-related protein Rab-4A 109 6e-24
sp|Q9GP33|RAB4A_ECHMU Probable Ras-related protein Rab-4A 106 4e-23
sp|P51146|RAB4B_RAT Ras-related protein Rab-4B >gi|46577105... 104 2e-22
sp|P61018|RAB4B_HUMAN Ras-related protein Rab-4B >gi|465776... 103 4e-22
sp|Q91V41|RAB14_MOUSE Ras-related protein Rab-14 93 5e-19
sp|P61107|RAB14_RAT Ras-related protein Rab-14 >gi|46577643... 93 5e-19
>sp|P20338|RAB4A_HUMAN Ras-related protein Rab-4A
Length = 213
Score = 110 bits (275), Expect = 3e-24
Identities = 64/144 (44%), Positives = 92/144 (63%), Gaps = 1/144 (0%)
Frame = +1
Query: 1 ALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFS 180
AL+VYDIT+R+++NA+ NWL+DA+ LA N+ IL GNKKDL A REV++ EA F+
Sbjct: 84 ALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDL---DADREVTFLEASRFA 140
Query: 181 KENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDLSDNIAQNSSSQNSGDIRKRWNR 360
+ENE+ F ETSA+ GE++++ F++CAR +++K ES +L + S GD R R
Sbjct: 141 QENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPE--RMGSGIQYGDAALRQLR 198
Query: 361 LSGSPAGGIRLSRARA-NSSNCQC 429
SP RA+A N+ C C
Sbjct: 199 ---SP------RRAQAPNAQECGC 213
>sp|Q6PHI9|RAB4A_BRARE Ras-related protein Rab-4A
Length = 213
Score = 110 bits (274), Expect = 4e-24
Identities = 51/98 (52%), Positives = 76/98 (77%)
Frame = +1
Query: 1 ALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFS 180
AL+VYDIT+R+++NA+ NWL+DA+ LA N+ IL GNKKDL A REV++ EA F+
Sbjct: 84 ALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDL---DADREVTFLEASRFA 140
Query: 181 KENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDL 294
+ENE+ F ETSA+ GE++++ F++CAR +++K ES +L
Sbjct: 141 QENELMFLETSALTGENVEEAFVQCARKILNKIESGEL 178
>sp|Q68EK7|RAB4B_BRARE Ras-related protein Rab-4B
Length = 213
Score = 109 bits (273), Expect = 5e-24
Identities = 51/98 (52%), Positives = 77/98 (78%)
Frame = +1
Query: 1 ALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFS 180
AL+VYDIT+R+++NA+ NWL+DA++LA N+ IL GNKKDL A REV++ EA F+
Sbjct: 84 ALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKDL---DADREVTFLEASRFA 140
Query: 181 KENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDL 294
+ENE+ F ETSA+ GE++++ F++CAR++ +K ES +L
Sbjct: 141 QENELMFLETSALTGENVEEAFLKCARSIPNKIESGEL 178
>sp|P05714|RAB4A_RAT Ras-related protein Rab-4A
Length = 213
Score = 109 bits (272), Expect = 6e-24
Identities = 51/98 (52%), Positives = 76/98 (77%)
Frame = +1
Query: 1 ALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFS 180
AL+VYDIT+R+++NA+ NWL+DA+ LA N+ IL GNKKDL A REV++ EA F+
Sbjct: 84 ALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDL---DADREVTFLEASRFA 140
Query: 181 KENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDL 294
+ENE+ F ETSA+ GE++++ F++CAR +++K ES +L
Sbjct: 141 QENELMFLETSALTGENVEEAFMQCARKILNKIESGEL 178
>sp|P56371|RAB4A_MOUSE Ras-related protein Rab-4A
Length = 213
Score = 109 bits (272), Expect = 6e-24
Identities = 51/98 (52%), Positives = 76/98 (77%)
Frame = +1
Query: 1 ALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFS 180
AL+VYDIT+R+++NA+ NWL+DA+ LA N+ IL GNKKDL A REV++ EA F+
Sbjct: 84 ALLVYDITSRETYNALTNWLTDARMLASQNIVLILCGNKKDL---DADREVTFLEASRFA 140
Query: 181 KENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDL 294
+ENE+ F ETSA+ GE++++ F++CAR +++K ES +L
Sbjct: 141 QENELMFLETSALTGENVEEAFMQCARKILNKIESGEL 178
>sp|Q9GP33|RAB4A_ECHMU Probable Ras-related protein Rab-4A
Length = 223
Score = 106 bits (265), Expect = 4e-23
Identities = 62/143 (43%), Positives = 85/143 (59%), Gaps = 1/143 (0%)
Frame = +1
Query: 4 LVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFSK 183
L+VYDITNR SF AV WL DA+ LA + ILVGNKKDL D +V++ EA F++
Sbjct: 86 LLVYDITNRTSFGAVEQWLGDARHLATPGVVVILVGNKKDLRD--TDGQVTHWEANTFAQ 143
Query: 184 ENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDL-SDNIAQNSSSQNSGDIRKRWNR 360
EN +QF ETSA+ GE+IDD F C R ++SK +S +L +D + S+ Q+ +
Sbjct: 144 ENGLQFIETSALTGENIDDAFTSCVRVLLSKVKSGELGADRLLVGSNKQHLQAVNL---T 200
Query: 361 LSGSPAGGIRLSRARANSSNCQC 429
S + + S A A+S C C
Sbjct: 201 ASATSVSASQSSAATAHSDTCLC 223
>sp|P51146|RAB4B_RAT Ras-related protein Rab-4B
sp|Q91ZR1|RAB4B_MOUSE Ras-related protein Rab-4B
Length = 213
Score = 104 bits (259), Expect = 2e-22
Identities = 52/117 (44%), Positives = 81/117 (69%)
Frame = +1
Query: 1 ALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFS 180
AL+VYDIT+R+++N++ WL+DA++LA N+ IL GNKKDL REV++ EA F+
Sbjct: 84 ALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDL---DPEREVTFLEASRFA 140
Query: 181 KENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDLSDNIAQNSSSQNSGDIRKR 351
+ENE+ F ETSA+ GE++++ F++CAR +++K +S +L + S GDI R
Sbjct: 141 QENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPE--RMGSGIQYGDISLR 195
>sp|P61018|RAB4B_HUMAN Ras-related protein Rab-4B
sp|P61017|RAB4B_CANFA Ras-related protein Rab-4B
Length = 213
Score = 103 bits (257), Expect = 4e-22
Identities = 47/98 (47%), Positives = 75/98 (76%)
Frame = +1
Query: 1 ALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFS 180
AL+VYDIT+R+++N++ WL+DA++LA N+ IL GNKKDL REV++ EA F+
Sbjct: 84 ALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDL---DPEREVTFLEASRFA 140
Query: 181 KENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDL 294
+ENE+ F ETSA+ GE++++ F++CAR +++K +S +L
Sbjct: 141 QENELMFLETSALTGENVEEAFLKCARTILNKIDSGEL 178
>sp|Q91V41|RAB14_MOUSE Ras-related protein Rab-14
Length = 215
Score = 93.2 bits (230), Expect = 5e-19
Identities = 50/143 (34%), Positives = 77/143 (53%)
Frame = +1
Query: 1 ALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFS 180
AL+VYDIT R ++N + +WL+DA++L N IL+GNK DL +A R+V+Y EA+ F+
Sbjct: 87 ALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADL---EAQRDVTYEEAKQFA 143
Query: 181 KENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDLSDNIAQNSSSQNSGDIRKRWNR 360
+EN + F E SA GE+++D F+E A+ + + L N A++
Sbjct: 144 EENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHK---------- 193
Query: 361 LSGSPAGGIRLSRARANSSNCQC 429
+P GG S + C C
Sbjct: 194 -PSAPQGGRLTSEPQPQREGCGC 215
>sp|P61107|RAB14_RAT Ras-related protein Rab-14
sp|P61106|RAB14_HUMAN Ras-related protein Rab-14
Length = 215
Score = 93.2 bits (230), Expect = 5e-19
Identities = 50/143 (34%), Positives = 77/143 (53%)
Frame = +1
Query: 1 ALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFS 180
AL+VYDIT R ++N + +WL+DA++L N IL+GNK DL +A R+V+Y EA+ F+
Sbjct: 87 ALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADL---EAQRDVTYEEAKQFA 143
Query: 181 KENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDLSDNIAQNSSSQNSGDIRKRWNR 360
+EN + F E SA GE+++D F+E A+ + + L N A++
Sbjct: 144 EENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHK---------- 193
Query: 361 LSGSPAGGIRLSRARANSSNCQC 429
+P GG S + C C
Sbjct: 194 -PSAPQGGRLTSEPQPQREGCGC 215
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,916,835
Number of Sequences: 369166
Number of extensions: 1352713
Number of successful extensions: 3857
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3683
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3751
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4895780500
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)