Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_G22
(569 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8INK6|PGPLB_DROME Peptidoglycan-recognition protein-LB ... 156 4e-38
sp|Q96PD5|PGRP2_HUMAN N-acetylmuramoyl-L-alanine amidase pr... 148 8e-36
sp|Q8VCS0|PGRP2_MOUSE N-acetylmuramoyl-L-alanine amidase pr... 147 2e-35
sp|Q866Y3|PGRP2_PIG N-acetylmuramoyl-L-alanine amidase prec... 140 3e-33
sp|Q70PY2|PGSB1_DROME Peptidoglycan-recognition protein-SB1... 137 2e-32
sp|Q96LB9|PGRP3_HUMAN Peptidoglycan recognition protein I-a... 135 7e-32
sp|Q70PU1|PGSC2_DROSI Peptidoglycan-recognition protein-SC2... 132 8e-31
sp|Q70PU2|PGSC1_DROSI Peptidoglycan-recognition protein-SC1... 130 2e-30
sp|Q9VYX7|PGPSA_DROME Peptidoglycan-recognition protein-SA ... 130 3e-30
sp|Q8SPP7|PGRP_BOVIN Peptidoglycan recognition protein prec... 127 2e-29
>sp|Q8INK6|PGPLB_DROME Peptidoglycan-recognition protein-LB precursor
Length = 232
Score = 156 bits (394), Expect = 4e-38
Identities = 72/161 (44%), Positives = 95/161 (59%)
Frame = +1
Query: 58 IINREQWGARDSKSIEILNSLPKYIFIHHTSTPGACYDLNQCMKAMRDIQKFHMDDRKWD 237
+++R WGAR KS+E Y+ IHH+ P CY CMK+MRD+Q FH +R W+
Sbjct: 32 LLSRSDWGARLPKSVEHFQGPAPYVIIHHSYMPAVCYSTPDCMKSMRDMQDFHQLERGWN 91
Query: 238 DIGYSFAIGSDGRVYEGRGWDRVGAHTLGYNSVGLGFVVIGNYETSPPNDLAINMLIKLI 417
DIGYSF IG DG +Y GRG++ +GAH YN +G V+IG++ T P ++ LI
Sbjct: 92 DIGYSFGIGGDGMIYTGRGFNVIGAHAPKYNDKSVGIVLIGDWRTELPPKQMLDAAKNLI 151
Query: 418 EYAVENEKIDKDYILRGHRDVRPTSCPGQSLYDIIQKWPHY 540
+ V ID Y L GHR VR T CPG L+ I WPH+
Sbjct: 152 AFGVFKGYIDPAYKLLGHRQVRDTECPGGRLFAEISSWPHF 192
>sp|Q96PD5|PGRP2_HUMAN N-acetylmuramoyl-L-alanine amidase precursor (Peptidoglycan
recognition protein long) (PGRP-L) (Peptidoglycan
recognition protein 2)
Length = 576
Score = 148 bits (374), Expect = 8e-36
Identities = 71/161 (44%), Positives = 98/161 (60%), Gaps = 3/161 (1%)
Frame = +1
Query: 67 REQWGARDSKSIEILNSLPK-YIFIHHTSTPGA-CYDLNQCMKAMRDIQKFHMDDRKWDD 240
R +WGA + L LP ++++HHT P C D +C MR +Q++H D + W D
Sbjct: 385 RCRWGAAPYRGRPKLLQLPLGFLYVHHTYVPAPPCTDFTRCAANMRSMQRYHQDTQGWGD 444
Query: 241 IGYSFAIGSDGRVYEGRGWDRVGAHTLGYNSVGLGFVVIGNYETSPPNDLAINML-IKLI 417
IGYSF +GSDG VYEGRGW VGAHTLG+NS G G ++GNY + P + A+ + L
Sbjct: 445 IGYSFVVGSDGYVYEGRGWHWVGAHTLGHNSRGFGVAIVGNYTAALPTEAALRTVRDTLP 504
Query: 418 EYAVENEKIDKDYILRGHRDVRPTSCPGQSLYDIIQKWPHY 540
AV + DY L GHR + T CPG +L+D+++ WPH+
Sbjct: 505 SCAVRAGLLRPDYALLGHRQLVRTDCPGDALFDLLRTWPHF 545
>sp|Q8VCS0|PGRP2_MOUSE N-acetylmuramoyl-L-alanine amidase precursor (Peptidoglycan
recognition protein long) (PGRP-L) (Peptidoglycan
recognition protein 2) (TagL)
Length = 530
Score = 147 bits (371), Expect = 2e-35
Identities = 72/161 (44%), Positives = 97/161 (60%), Gaps = 3/161 (1%)
Frame = +1
Query: 67 REQWGARDSKSIEILNSLPK-YIFIHHTSTPGA-CYDLNQCMKAMRDIQKFHMDDRKWDD 240
R +WGA + LP ++++HHT P C C MR +Q+FH D RKWDD
Sbjct: 365 RCRWGAAPYRGHPTPLRLPLGFLYVHHTYVPAPPCTTFQSCAADMRSMQRFHQDVRKWDD 424
Query: 241 IGYSFAIGSDGRVYEGRGWDRVGAHTLGYNSVGLGFVVIGNYETSPPNDLAINML-IKLI 417
IGYSF +GSDG +Y+GRGW VGAHT GYNS G G +GNY S PN+ A+N + L
Sbjct: 425 IGYSFVVGSDGYLYQGRGWHWVGAHTRGYNSRGFGVAFVGNYTGSLPNEAALNTVRDALP 484
Query: 418 EYAVENEKIDKDYILRGHRDVRPTSCPGQSLYDIIQKWPHY 540
A+ + DY L GHR + T CPG +L+++++ WPH+
Sbjct: 485 SCAIRAGLLRPDYKLLGHRQLVLTHCPGNALFNLLRTWPHF 525
>sp|Q866Y3|PGRP2_PIG N-acetylmuramoyl-L-alanine amidase precursor (Peptidoglycan
recognition protein long) (PGRP-L) (Peptidoglycan
recognition protein 2)
Length = 598
Score = 140 bits (352), Expect = 3e-33
Identities = 70/161 (43%), Positives = 96/161 (59%), Gaps = 3/161 (1%)
Frame = +1
Query: 67 REQWGARDSKSIEILNSLPK-YIFIHHTSTPGA-CYDLNQCMKAMRDIQKFHMDDRKWDD 240
R +WGA + LP +++IHHT P C D C MR +Q+FH+D + WDD
Sbjct: 407 RCRWGAAPYRGSPKPLKLPLGFLYIHHTYVPARPCTDFALCAANMRSMQRFHLDTQGWDD 466
Query: 241 IGYSFAIGSDGRVYEGRGWDRVGAHTLGYNSVGLGFVVIGNYETSPPNDLAINML-IKLI 417
IGYSF +GSDG VYEGRGW VGAHT +NS G G +IGNY P++ A+ + +L
Sbjct: 467 IGYSFVVGSDGYVYEGRGWHWVGAHTRDHNSRGFGVALIGNYTAELPSEAALRAVRDELP 526
Query: 418 EYAVENEKIDKDYILRGHRDVRPTSCPGQSLYDIIQKWPHY 540
AV + DY L GHR + T CPG +L+++++ WP +
Sbjct: 527 HCAVRAGLLQPDYALLGHRQLVRTDCPGDALFNMLRTWPRF 567
>sp|Q70PY2|PGSB1_DROME Peptidoglycan-recognition protein-SB1 precursor
Length = 190
Score = 137 bits (345), Expect = 2e-32
Identities = 62/158 (39%), Positives = 91/158 (57%)
Frame = +1
Query: 67 REQWGARDSKSIEILNSLPKYIFIHHTSTPGACYDLNQCMKAMRDIQKFHMDDRKWDDIG 246
R WGA ++S ++ Y+ IHH+ P C QC + +++IQ H R + DIG
Sbjct: 30 RSSWGAVSARSPSRISGAVDYVIIHHSDNPNGCSTSEQCKRMIKNIQSDHKGRRNFSDIG 89
Query: 247 YSFAIGSDGRVYEGRGWDRVGAHTLGYNSVGLGFVVIGNYETSPPNDLAINMLIKLIEYA 426
Y+F + DG+VYEGRG+ G+H+ YN +G V IGN+E S P+ + LIE A
Sbjct: 90 YNFIVAGDGKVYEGRGFGLQGSHSPNYNRKSIGIVFIGNFERSAPSAQMLQNAKDLIELA 149
Query: 427 VENEKIDKDYILRGHRDVRPTSCPGQSLYDIIQKWPHY 540
+ + +Y L GHR + TSCPG +LY+ I+ WPH+
Sbjct: 150 KQRGYLKDNYTLFGHRQTKATSCPGDALYNEIKTWPHW 187
>sp|Q96LB9|PGRP3_HUMAN Peptidoglycan recognition protein I-alpha precursor (Peptidoglycan
recognition protein intermediate alpha) (PGRP-I-alpha)
(PGLYRPIalpha) (Peptidoglycan recognition protein 3)
Length = 341
Score = 135 bits (340), Expect = 7e-32
Identities = 69/162 (42%), Positives = 93/162 (57%)
Frame = +1
Query: 55 DIINREQWGARDSKSIEILNSLPKYIFIHHTSTPGACYDLNQCMKAMRDIQKFHMDDRKW 234
+II R W AR++ + +N KY+ I HT+ +C C +R+IQ FHMD R +
Sbjct: 180 NIIKRSAWEARETHCPK-MNLPAKYVIIIHTAGT-SCTVSTDCQTVVRNIQSFHMDTRNF 237
Query: 235 DDIGYSFAIGSDGRVYEGRGWDRVGAHTLGYNSVGLGFVVIGNYETSPPNDLAINMLIKL 414
DIGY F +G DG VYEG GW G+HT G+N + LG IG + PPN A+ L
Sbjct: 238 CDIGYHFLVGQDGGVYEGVGWHIQGSHTYGFNDIALGIAFIGYFVEKPPNAAALEAAQDL 297
Query: 415 IEYAVENEKIDKDYILRGHRDVRPTSCPGQSLYDIIQKWPHY 540
I+ AV + +Y+L GH DV PGQ+LY+II WPH+
Sbjct: 298 IQCAVVEGYLTPNYLLMGHSDVVNILSPGQALYNIISTWPHF 339
Score = 90.5 bits (223), Expect = 3e-18
Identities = 48/135 (35%), Positives = 70/135 (51%), Gaps = 1/135 (0%)
Frame = +1
Query: 58 IINREQWGARDSKSIEILNSLPKYIFIHHTSTPGA-CYDLNQCMKAMRDIQKFHMDDRKW 234
I++R++WGAR +L YI PG C + C + +R +Q + W
Sbjct: 23 IVSRKEWGARPLACRALLTLPVAYIITDQL--PGMQCQQQSVCSQMLRGLQSHSVYTIGW 80
Query: 235 DDIGYSFAIGSDGRVYEGRGWDRVGAHTLGYNSVGLGFVVIGNYETSPPNDLAINMLIKL 414
D+ Y+F +G DGRVYEG GW+ G HT GYN++ LG GN S P+ A++ L
Sbjct: 81 CDVAYNFLVGDDGRVYEGVGWNIQGLHTQGYNNISLGIAFFGNKIGSSPSPAALSAAEGL 140
Query: 415 IEYAVENEKIDKDYI 459
I YA++ + YI
Sbjct: 141 ISYAIQKGHLSPRYI 155
>sp|Q70PU1|PGSC2_DROSI Peptidoglycan-recognition protein-SC2 precursor
Length = 184
Score = 132 bits (331), Expect = 8e-31
Identities = 64/161 (39%), Positives = 91/161 (56%)
Frame = +1
Query: 58 IINREQWGARDSKSIEILNSLPKYIFIHHTSTPGACYDLNQCMKAMRDIQKFHMDDRKWD 237
I+++ +WG R + S L S Y IHHT+ C C+ +++IQ +HMD W
Sbjct: 23 IVSKSEWGGRSATSKTSLASYLSYAVIHHTAG-NYCSTKAACITQLKNIQAYHMDSLGWA 81
Query: 238 DIGYSFAIGSDGRVYEGRGWDRVGAHTLGYNSVGLGFVVIGNYETSPPNDLAINMLIKLI 417
DIGY+F IG DG VYEGRGW+ +GAH +NS +G +GNY T+ I L+
Sbjct: 82 DIGYNFLIGGDGNVYEGRGWNVMGAHATNWNSKSIGISFLGNYNTNTLTSAQITAAKGLL 141
Query: 418 EYAVENEKIDKDYILRGHRDVRPTSCPGQSLYDIIQKWPHY 540
AV +I YIL GHR V T CPG ++++ I+ W ++
Sbjct: 142 SDAVSRGQIVSGYILYGHRQVGSTECPGTNIWNEIRTWSNW 182
>sp|Q70PU2|PGSC1_DROSI Peptidoglycan-recognition protein-SC1a/b precursor
Length = 185
Score = 130 bits (328), Expect = 2e-30
Identities = 63/163 (38%), Positives = 92/163 (56%), Gaps = 2/163 (1%)
Frame = +1
Query: 58 IINREQWGARDSKSIEILNSLPKYIFIHHTSTPGACYDLNQCMKAMRDIQKFHMDDRKWD 237
++++ +WG R +K L + Y IHHT+ C QC ++ +Q +HMD W
Sbjct: 24 VVSKAEWGGRGAKWTVALGNYLSYAIIHHTAG-SYCETRAQCNAVLQSVQAYHMDSLGWP 82
Query: 238 DIGYSFAIGSDGRVYEGRGWDRVGAHTLGYNSVGLGFVVIGNY--ETSPPNDLAINMLIK 411
DIGY+F IG DG VYEGRGW+ +GAH +N +G +GNY +T PN I+ +
Sbjct: 83 DIGYNFLIGGDGNVYEGRGWNNMGAHAAEWNPYSIGISFLGNYNWDTLEPN--MISAAQQ 140
Query: 412 LIEYAVENEKIDKDYILRGHRDVRPTSCPGQSLYDIIQKWPHY 540
L+ AV ++ YIL GHR V T CPG +++ I+ W H+
Sbjct: 141 LLNDAVNRGQLSSGYILYGHRQVSATECPGTHIWNEIRGWSHW 183
>sp|Q9VYX7|PGPSA_DROME Peptidoglycan-recognition protein-SA precursor (Protein semmelweis)
Length = 203
Score = 130 bits (326), Expect = 3e-30
Identities = 61/158 (38%), Positives = 93/158 (58%)
Frame = +1
Query: 67 REQWGARDSKSIEILNSLPKYIFIHHTSTPGACYDLNQCMKAMRDIQKFHMDDRKWDDIG 246
+ QWG + S + +Y+ IHHT T G C L +C + ++++Q +H ++ ++DI
Sbjct: 43 KRQWGGKPSLGLHYQVRPIRYVVIHHTVT-GECSGLLKCAEILQNMQAYHQNELDFNDIS 101
Query: 247 YSFAIGSDGRVYEGRGWDRVGAHTLGYNSVGLGFVVIGNYETSPPNDLAINMLIKLIEYA 426
Y+F IG+DG VYEG GW GAHT GYN++G G IGN+ P+D A+ L+
Sbjct: 102 YNFLIGNDGIVYEGTGWGLRGAHTYGYNAIGTGIAFIGNFVDKLPSDAALQAAKDLLACG 161
Query: 427 VENEKIDKDYILRGHRDVRPTSCPGQSLYDIIQKWPHY 540
V+ ++ +DY L V T PG +LY+ IQ+WPH+
Sbjct: 162 VQQGELSEDYALIAGSQVISTQSPGLTLYNEIQEWPHW 199
>sp|Q8SPP7|PGRP_BOVIN Peptidoglycan recognition protein precursor (Peptidoglycan
recognition protein short) (PGRP-S)
(Oligosaccharide-binding protein) (OBP)
Length = 190
Score = 127 bits (319), Expect = 2e-29
Identities = 61/162 (37%), Positives = 93/162 (57%), Gaps = 1/162 (0%)
Frame = +1
Query: 58 IINREQWGARDSKSIEILNSLPKYIFIHHTSTPGACYDLNQCMKAMRDIQKFHMDDRKWD 237
I++R +WGA SK + L +Y+ + HT+ C C + +++Q +H+ +R W
Sbjct: 27 IVSRGKWGALASKCSQRLRQPVRYVVVSHTAG-SVCNTPASCQRQAQNVQYYHVRERGWC 85
Query: 238 DIGYSFAIGSDGRVYEGRGWDRVGAHT-LGYNSVGLGFVVIGNYETSPPNDLAINMLIKL 414
D+GY+F IG DG VYEGRGW+ +GAH+ +N + +G +GNY P A+ L
Sbjct: 86 DVGYNFLIGEDGLVYEGRGWNTLGAHSGPTWNPIAIGISFMGNYMHRVPPASALRAAQSL 145
Query: 415 IEYAVENEKIDKDYILRGHRDVRPTSCPGQSLYDIIQKWPHY 540
+ + +Y ++GHRDV+ T PG LY IIQ+WPHY
Sbjct: 146 LACGAARGYLTPNYEVKGHRDVQQTLSPGDELYKIIQQWPHY 187
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,083,761
Number of Sequences: 369166
Number of extensions: 1468186
Number of successful extensions: 4036
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3885
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4012
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4177115900
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)