Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_027_F05 (356 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 (RalDH2) (RAL... 135 4e-32 sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 (RalDH2) (RALDH... 135 4e-32 sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial... 132 2e-31 sp|O94788|AL1A2_HUMAN Retinal dehydrogenase 2 (RalDH2) (RAL... 132 2e-31 sp|P81178|ALDH2_MESAU Aldehyde dehydrogenase, mitochondrial... 132 2e-31 sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial... 132 2e-31 sp|P11884|ALDH2_RAT Aldehyde dehydrogenase, mitochondrial p... 132 2e-31 sp|P20000|ALDH2_BOVIN Aldehyde dehydrogenase, mitochondrial... 132 3e-31 sp|P27463|AL1A1_CHICK Retinal dehydrogenase 1 (RalDH1) (RAL... 131 4e-31 sp|P47738|ALDH2_MOUSE Aldehyde dehydrogenase, mitochondrial... 130 9e-31
>sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II)) (Retinaldehyde-specific dehydrogenase type 2) (Aldehyde dehydrogenase family 1 member A2) Length = 499 Score = 135 bits (339), Expect = 4e-32 Identities = 62/98 (63%), Positives = 79/98 (80%) Frame = +2 Query: 2 PVQSVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVT 181 PVQ + +F TM+EVIERANNSD+GL A VFT+DINKA+M++ A++AG+VW+NCY+ Sbjct: 402 PVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQ 461 Query: 182 APFGGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQKNS 295 +PFGGFK SG GRE+G +GL Y EVK VT+ IPQKNS Sbjct: 462 SPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS 499
>sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II)) (Retinaldehyde-specific dehydrogenase type 2) (Aldehyde dehydrogenase family 1 member A2) Length = 499 Score = 135 bits (339), Expect = 4e-32 Identities = 62/98 (63%), Positives = 79/98 (80%) Frame = +2 Query: 2 PVQSVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVT 181 PVQ + +F TM+EVIERANNSD+GL A VFT+DINKA+M++ A++AG+VW+NCY+ Sbjct: 402 PVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQ 461 Query: 182 APFGGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQKNS 295 +PFGGFK SG GRE+G +GL Y EVK VT+ IPQKNS Sbjct: 462 SPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS 499
>sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2) (ALDHI) (ALDH-E2) Length = 517 Score = 132 bits (333), Expect = 2e-31 Identities = 62/98 (63%), Positives = 76/98 (77%) Frame = +2 Query: 2 PVQSVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVT 181 PV + KF T+EEV+ RANNS YGL A VFT D++KA ++QAL+AG+VWVNCYDV Sbjct: 420 PVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQ 479 Query: 182 APFGGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQKNS 295 +PFGG+K SG GRELG YGL+ Y EVK VT+ +PQKNS Sbjct: 480 SPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS 517
>sp|O94788|AL1A2_HUMAN Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II)) (Retinaldehyde-specific dehydrogenase type 2) (Aldehyde dehydrogenase family 1 member A2) Length = 499 Score = 132 bits (333), Expect = 2e-31 Identities = 61/98 (62%), Positives = 78/98 (79%) Frame = +2 Query: 2 PVQSVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVT 181 PVQ + +F TM+EVIERANNSD+GL A VFT+DINKA+ ++ A++AG+VW+NCY+ Sbjct: 402 PVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQ 461 Query: 182 APFGGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQKNS 295 +PFGGFK SG GRE+G +GL Y EVK VT+ IPQKNS Sbjct: 462 SPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS 499
>sp|P81178|ALDH2_MESAU Aldehyde dehydrogenase, mitochondrial (ALDH class 2) (ALDH1) (ALDH-E2) Length = 500 Score = 132 bits (333), Expect = 2e-31 Identities = 62/98 (63%), Positives = 76/98 (77%) Frame = +2 Query: 2 PVQSVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVT 181 PV + KF T+EEV+ RANNS YGL A VFT D++KA ++QAL+AG+VW+NCYDV Sbjct: 403 PVMQILKFKTIEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQ 462 Query: 182 APFGGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQKNS 295 +PFGG+K SG GRELG YGL+ Y EVK VTI +PQKNS Sbjct: 463 SPFGGYKMSGSGRELGEYGLQAYTEVKTVTIKVPQKNS 500
>sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial (ALDH class 2) (ALDHI) (ALDH-E2) Length = 500 Score = 132 bits (332), Expect = 2e-31 Identities = 62/98 (63%), Positives = 76/98 (77%) Frame = +2 Query: 2 PVQSVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVT 181 PV + KF T+EEV+ RANNS YGL A VFT D++KA ++QAL+AG+VW+NCYDV Sbjct: 403 PVMQILKFKTIEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQ 462 Query: 182 APFGGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQKNS 295 +PFGG+K SG GRELG YGL+ Y EVK VTI +PQKNS Sbjct: 463 SPFGGYKMSGNGRELGEYGLQAYTEVKTVTIKVPQKNS 500
>sp|P11884|ALDH2_RAT Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2) (ALDH1) (ALDH-E2) Length = 519 Score = 132 bits (332), Expect = 2e-31 Identities = 61/98 (62%), Positives = 76/98 (77%) Frame = +2 Query: 2 PVQSVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVT 181 PV + KF T+EEV+ RANNS YGL A VFT D++KA ++QAL+AG+VW+NCYDV Sbjct: 422 PVMQILKFKTIEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQ 481 Query: 182 APFGGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQKNS 295 +PFGG+K SG GRELG YGL+ Y EVK VT+ +PQKNS Sbjct: 482 SPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS 519
>sp|P20000|ALDH2_BOVIN Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2) (ALDHI) (ALDH-E2) Length = 520 Score = 132 bits (331), Expect = 3e-31 Identities = 62/98 (63%), Positives = 76/98 (77%) Frame = +2 Query: 2 PVQSVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVT 181 PV + KF +MEEV+ RANNS YGL A VFT D++KA ++QAL+AG+VWVNCYDV Sbjct: 423 PVMQILKFKSMEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQ 482 Query: 182 APFGGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQKNS 295 +PFGG+K SG GRELG YGL+ Y EVK VT+ +PQKNS Sbjct: 483 SPFGGYKLSGSGRELGEYGLQAYTEVKTVTVRVPQKNS 520
>sp|P27463|AL1A1_CHICK Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) Length = 509 Score = 131 bits (330), Expect = 4e-31 Identities = 63/98 (64%), Positives = 73/98 (74%) Frame = +2 Query: 2 PVQSVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVT 181 PVQ + KF T++EVI+RANN+ YGL A VFT DI+KA+ AL+AG+VWVNCY Sbjct: 412 PVQQIMKFKTIDEVIKRANNTTYGLAAAVFTKDIDKALTFASALQAGTVWVNCYSAFSAQ 471 Query: 182 APFGGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQKNS 295 PFGGFK SG GRELG YGL+ Y EVK VTI IPQKNS Sbjct: 472 CPFGGFKMSGNGRELGEYGLQEYTEVKTVTIKIPQKNS 509
>sp|P47738|ALDH2_MOUSE Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2) (AHD-M1) (ALDHI) (ALDH-E2) Length = 519 Score = 130 bits (327), Expect = 9e-31 Identities = 60/98 (61%), Positives = 76/98 (77%) Frame = +2 Query: 2 PVQSVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVT 181 PV + KF T+EEV+ RAN+S YGL A VFT D++KA ++QAL+AG+VW+NCYDV Sbjct: 422 PVMQILKFKTIEEVVGRANDSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQ 481 Query: 182 APFGGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQKNS 295 +PFGG+K SG GRELG YGL+ Y EVK VT+ +PQKNS Sbjct: 482 SPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS 519
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,106,410 Number of Sequences: 369166 Number of extensions: 600955 Number of successful extensions: 1457 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1423 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1433 length of database: 68,354,980 effective HSP length: 86 effective length of database: 52,467,770 effective search space used: 1678968640 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)