Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_F02
(821 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99832|TCPH_HUMAN T-complex protein 1, eta subunit (TCP-... 381 e-105
sp|Q5R5C8|TCPH_PONPY T-complex protein 1, eta subunit (TCP-... 381 e-105
sp|P80313|TCPH_MOUSE T-complex protein 1, eta subunit (TCP-... 379 e-105
sp|P87153|TCPH_SCHPO Probable T-complex protein 1, eta subu... 337 2e-92
sp|P42943|TCPH_YEAST T-complex protein 1, eta subunit (TCP-... 308 2e-83
sp|P54409|TCPH_TETPY T-complex protein 1, eta subunit (TCP-... 281 2e-75
sp|O77323|TCPH_PLAF7 T-complex protein 1, eta subunit (TCP-... 271 1e-72
sp|P50016|THS_METKA Thermosome subunit (Chaperonin-like com... 184 3e-46
sp|O28045|THSA_ARCFU Thermosome alpha subunit (Thermosome s... 183 4e-46
sp|P48424|THSA_THEAC Thermosome alpha subunit (Thermosome s... 175 1e-43
>sp|Q99832|TCPH_HUMAN T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta) (HIV-1 Nef
interacting protein)
Length = 543
Score = 381 bits (979), Expect = e-105
Identities = 182/237 (76%), Positives = 211/237 (89%)
Frame = +2
Query: 2 VLSKLPIGDVATQYFADRDMFCAGRVTEEDLKRTMAACGGAIQTTVKDITDDTLGKCESF 181
VLSKLPIGDVATQYFADRDMFCAGRV EEDLKRTM ACGG+IQT+V ++ D LG+C+ F
Sbjct: 289 VLSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVF 348
Query: 182 EEVQIGGERFNIFVGCPEAKTCTIILRGGSEQFMEETERSLHDAIMIVRRAMKNDAVVAG 361
EE QIGGER+N F GCP+AKTCT ILRGG+EQFMEETERSLHDAIMIVRRA+KND+VVAG
Sbjct: 349 EETQIGGERYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAG 408
Query: 362 GGAIDMEISKYLRDYSRNIHGRDQQFIGAMARAFEVIPRQLCENAGFDATNILNKLRQKH 541
GGAI+ME+SKYLRDYSR I G+ Q IGA A+A E+IPRQLC+NAGFDATNILNKLR +H
Sbjct: 409 GGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARH 468
Query: 542 AQGKIWCGVDIMNEDIADNFEACVWEPALVKSNAITAATEAACMVLTLDETIRNAKS 712
AQG W GVDI NEDIADNFEA VWEPA+V+ NA+TAA+EAAC+++++DETI+N +S
Sbjct: 469 AQGGTWYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRS 525
>sp|Q5R5C8|TCPH_PONPY T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta)
Length = 543
Score = 381 bits (979), Expect = e-105
Identities = 182/237 (76%), Positives = 211/237 (89%)
Frame = +2
Query: 2 VLSKLPIGDVATQYFADRDMFCAGRVTEEDLKRTMAACGGAIQTTVKDITDDTLGKCESF 181
VLSKLPIGDVATQYFADRDMFCAGRV EEDLKRTM ACGG+IQT+V ++ D LG+C+ F
Sbjct: 289 VLSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVF 348
Query: 182 EEVQIGGERFNIFVGCPEAKTCTIILRGGSEQFMEETERSLHDAIMIVRRAMKNDAVVAG 361
EE QIGGER+N F GCP+AKTCT ILRGG+EQFMEETERSLHDAIMIVRRA+KND+VVAG
Sbjct: 349 EETQIGGERYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAG 408
Query: 362 GGAIDMEISKYLRDYSRNIHGRDQQFIGAMARAFEVIPRQLCENAGFDATNILNKLRQKH 541
GGAI+ME+SKYLRDYSR I G+ Q IGA A+A E+IPRQLC+NAGFDATNILNKLR +H
Sbjct: 409 GGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARH 468
Query: 542 AQGKIWCGVDIMNEDIADNFEACVWEPALVKSNAITAATEAACMVLTLDETIRNAKS 712
AQG W GVDI NEDIADNFEA VWEPA+V+ NA+TAA+EAAC+++++DETI+N +S
Sbjct: 469 AQGGTWYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRS 525
>sp|P80313|TCPH_MOUSE T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta)
Length = 544
Score = 379 bits (973), Expect = e-105
Identities = 180/237 (75%), Positives = 211/237 (89%)
Frame = +2
Query: 2 VLSKLPIGDVATQYFADRDMFCAGRVTEEDLKRTMAACGGAIQTTVKDITDDTLGKCESF 181
+LSKLPIGDVATQYFADRDMFCAGRV EEDLKRTM ACGG+IQT+V + D LG C+ F
Sbjct: 289 ILSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALVPDVLGHCQVF 348
Query: 182 EEVQIGGERFNIFVGCPEAKTCTIILRGGSEQFMEETERSLHDAIMIVRRAMKNDAVVAG 361
EE QIGGER+N F GCP+AKTCTIILRGG+EQFMEETERSLHDAIMIVRRA+KND+VVAG
Sbjct: 349 EETQIGGERYNFFTGCPKAKTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAG 408
Query: 362 GGAIDMEISKYLRDYSRNIHGRDQQFIGAMARAFEVIPRQLCENAGFDATNILNKLRQKH 541
GGAI+ME+SKYLRDYSR I G+ Q IGA A+A E+IPRQLC+NAGFDATNILNKLR +H
Sbjct: 409 GGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARH 468
Query: 542 AQGKIWCGVDIMNEDIADNFEACVWEPALVKSNAITAATEAACMVLTLDETIRNAKS 712
AQG +W GVDI NE+IADNF+A VWEPA+V+ NA+TAA+EAAC+++++DETI+N +S
Sbjct: 469 AQGGMWYGVDINNENIADNFQAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRS 525
>sp|P87153|TCPH_SCHPO Probable T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta)
Length = 558
Score = 337 bits (865), Expect = 2e-92
Identities = 159/241 (65%), Positives = 202/241 (83%)
Frame = +2
Query: 2 VLSKLPIGDVATQYFADRDMFCAGRVTEEDLKRTMAACGGAIQTTVKDITDDTLGKCESF 181
VLSKLPIGD+ATQYFADRD+FCAGRV +DL R + A GG+IQ+T +I + LG C++F
Sbjct: 294 VLSKLPIGDLATQYFADRDIFCAGRVAADDLNRVVQAVGGSIQSTCSNIEEKHLGTCDTF 353
Query: 182 EEVQIGGERFNIFVGCPEAKTCTIILRGGSEQFMEETERSLHDAIMIVRRAMKNDAVVAG 361
EE QIGG+RFN+F GCP+AKTCT+ILRGG++QF+ E ERSLHDAIMIV+ A+KN+ VVAG
Sbjct: 354 EERQIGGDRFNLFEGCPKAKTCTLILRGGADQFIAEVERSLHDAIMIVKHALKNNLVVAG 413
Query: 362 GGAIDMEISKYLRDYSRNIHGRDQQFIGAMARAFEVIPRQLCENAGFDATNILNKLRQKH 541
GGA +ME+SKYLRDYS I G+ Q FI A AR+ EVIPRQLC+NAGFD+TNILNKLR +H
Sbjct: 414 GGACEMELSKYLRDYSLTISGKQQNFIAAFARSLEVIPRQLCDNAGFDSTNILNKLRMQH 473
Query: 542 AQGKIWCGVDIMNEDIADNFEACVWEPALVKSNAITAATEAACMVLTLDETIRNAKSKTP 721
A+G++W GVD+ +E +A+NFE VWEP+ VKSNAI +ATEAA ++L++DETI+N S+ P
Sbjct: 474 AKGEMWAGVDMDSEGVANNFEKFVWEPSTVKSNAILSATEAATLILSVDETIKNEPSQQP 533
Query: 722 E 724
+
Sbjct: 534 Q 534
>sp|P42943|TCPH_YEAST T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta)
Length = 550
Score = 308 bits (788), Expect = 2e-83
Identities = 148/239 (61%), Positives = 188/239 (78%)
Frame = +2
Query: 2 VLSKLPIGDVATQYFADRDMFCAGRVTEEDLKRTMAACGGAIQTTVKDITDDTLGKCESF 181
VLSKLPIGD+ATQ+FADR++FCAGRV+ +D+ R + A GG+IQ+T DI + LG C F
Sbjct: 293 VLSKLPIGDLATQFFADRNIFCAGRVSADDMNRVIQAVGGSIQSTTSDIKPEHLGTCALF 352
Query: 182 EEVQIGGERFNIFVGCPEAKTCTIILRGGSEQFMEETERSLHDAIMIVRRAMKNDAVVAG 361
EE+QIG ER+N+F GCP+AKTCT++LRGG+EQ + E ERSLHDAIMIV+RA++N +VAG
Sbjct: 353 EEMQIGSERYNLFQGCPQAKTCTLLLRGGAEQVIAEVERSLHDAIMIVKRALQNKLIVAG 412
Query: 362 GGAIDMEISKYLRDYSRNIHGRDQQFIGAMARAFEVIPRQLCENAGFDATNILNKLRQKH 541
GGA +ME+SK LRDYS+ I G+ Q I A A+A EVIPRQLCENAGFDA ILNKLR H
Sbjct: 413 GGATEMEVSKCLRDYSKTIAGKQQMIINAFAKALEVIPRQLCENAGFDAIEILNKLRLAH 472
Query: 542 AQGKIWCGVDIMNEDIADNFEACVWEPALVKSNAITAATEAACMVLTLDETIRNAKSKT 718
++G+ W GV E+I DNF VWEPALVK NA+ +ATEA ++L++DETI N S++
Sbjct: 473 SKGEKWYGVVFETENIGDNFAKFVWEPALVKINALNSATEATNLILSVDETITNKGSES 531
>sp|P54409|TCPH_TETPY T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta)
Length = 558
Score = 281 bits (719), Expect = 2e-75
Identities = 145/246 (58%), Positives = 183/246 (74%), Gaps = 5/246 (2%)
Frame = +2
Query: 2 VLSKLPIGDVATQYFADRDMFCAGRVTEEDLKRTMAACGGAIQTTVKDITDDTLGKCESF 181
VLSKLPIGD+ATQYFADR++FCAGRV ED+KR A G +QTTV ++ D LG C F
Sbjct: 289 VLSKLPIGDLATQYFADRNIFCAGRVDAEDIKRVQKATGSIVQTTVNGLSQDVLGTCGMF 348
Query: 182 EEVQIGGERFNIFVGCPEAKTCTIILRGGSEQFMEETERSLHDAIMIVRRAMKNDAVVAG 361
EE QIG ER+N+F CP +K+ TIILRGG+EQF+ E ERSL+DAIMIVRR MK + +V G
Sbjct: 349 EEQQIGAERYNLFQDCPHSKSATIILRGGAEQFIAEAERSLNDAIMIVRRCMKANKIVPG 408
Query: 362 GGAIDMEISKYLRDYSRNIHGRDQQFIGAMARAFEVIPRQLCENAGFDATNILNKLRQKH 541
GGAI++EIS+ LR +SR G+ Q I A A+A EVIP+ + +NAG D+ +LNKLRQKH
Sbjct: 409 GGAIELEISRLLRLHSRKTEGKVQLVINAFAKALEVIPKTIADNAGHDSIQVLNKLRQKH 468
Query: 542 A----QGKIWCGVDIMNED-IADNFEACVWEPALVKSNAITAATEAACMVLTLDETIRNA 706
A Q K + GVDI D I +NFE VWEP +V+ NA +AATEAAC +L++DET+RN
Sbjct: 469 ALESDQSKNF-GVDINAVDGIGNNFENFVWEPIIVRKNAFSAATEAACTILSIDETVRNP 527
Query: 707 KSKTPE 724
KS+ P+
Sbjct: 528 KSEQPK 533
>sp|O77323|TCPH_PLAF7 T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta)
Length = 539
Score = 271 bits (694), Expect = 1e-72
Identities = 133/239 (55%), Positives = 180/239 (75%), Gaps = 2/239 (0%)
Frame = +2
Query: 2 VLSKLPIGDVATQYFADRDMFCAGRVTEEDLKRTMAACGGAIQTTVKDITDDTLGKCESF 181
VLSKLPIGD+ATQ+FAD D+FCAGRV + DLKRT A G +QT++ ++ DD LG C F
Sbjct: 291 VLSKLPIGDIATQFFADHDIFCAGRVEDADLKRTANATGALVQTSLFNLNDDVLGTCGVF 350
Query: 182 EEVQIGGERFNIFVGCPEAKTCTIILRGGSEQFMEETERSLHDAIMIVRRAMKNDAVVAG 361
EEVQIG ER+NIF C + K+ TIILRGG++QF+EE ERS++DAIMIV R + N +V G
Sbjct: 351 EEVQIGNERYNIFKECLKTKSVTIILRGGAKQFIEEVERSINDAIMIVLRCITNSEIVPG 410
Query: 362 GGAIDMEISKYLRDYSRNIHGRDQQFIGAMARAFEVIPRQLCENAGFDATNILNKLRQKH 541
G+I+M++SKYLR YSR+I ++Q + + A+A E IPR L NAG+D+T+ILNKLR+KH
Sbjct: 411 AGSIEMQLSKYLRIYSRSICNKEQIVLFSFAKALESIPRHLSHNAGYDSTDILNKLRKKH 470
Query: 542 AQ--GKIWCGVDIMNEDIADNFEACVWEPALVKSNAITAATEAACMVLTLDETIRNAKS 712
++ IW GVD M DI + ++ C++E +K N I +ATEAAC++L++DETI+N S
Sbjct: 471 SEQTSDIWYGVDCMEGDIINAYDNCIFEVTKIKRNVIYSATEAACLILSIDETIKNPSS 529
>sp|P50016|THS_METKA Thermosome subunit (Chaperonin-like complex) (CLIC)
Length = 545
Score = 184 bits (466), Expect = 3e-46
Identities = 88/226 (38%), Positives = 144/226 (63%)
Frame = +2
Query: 20 IGDVATQYFADRDMFCAGRVTEEDLKRTMAACGGAIQTTVKDITDDTLGKCESFEEVQIG 199
I D+A Y A + + RV + D+++ A G I T + D++++ LG+ E EE ++
Sbjct: 299 IDDLAQHYLAKKGILAVRRVKKSDMQKLARATGARIVTNIDDLSEEDLGEAEVVEEKKVA 358
Query: 200 GERFNIFVGCPEAKTCTIILRGGSEQFMEETERSLHDAIMIVRRAMKNDAVVAGGGAIDM 379
G++ GC + K TI++RGG+E ++E ER++ DAI +V A+++ VVAGGGA ++
Sbjct: 359 GDKMIFVEGCKDPKAVTILIRGGTEHVVDEAERAIEDAIGVVAAALEDGKVVAGGGAPEV 418
Query: 380 EISKYLRDYSRNIHGRDQQFIGAMARAFEVIPRQLCENAGFDATNILNKLRQKHAQGKIW 559
E+++ LRD++ + GR+Q + A A A E+IPR L EN+G D ++L +LR KH G++
Sbjct: 419 EVARQLRDFADGVEGREQLAVEAFADALEIIPRTLAENSGLDPIDVLVQLRAKHEDGQVT 478
Query: 560 CGVDIMNEDIADNFEACVWEPALVKSNAITAATEAACMVLTLDETI 697
G+D+ + D+ D E V EP VK+ A+ +ATEAA M+L +D+ I
Sbjct: 479 AGIDVYDGDVKDMLEEGVVEPLRVKTQALASATEAAEMILRIDDVI 524
>sp|O28045|THSA_ARCFU Thermosome alpha subunit (Thermosome subunit 1) (Chaperonin alpha
subunit)
Length = 545
Score = 183 bits (465), Expect = 4e-46
Identities = 100/238 (42%), Positives = 145/238 (60%), Gaps = 3/238 (1%)
Frame = +2
Query: 20 IGDVATQYFADRDMFCAGRVTEEDLKRTMAACGGAIQTTVKDITDDTLGKCESFEEVQIG 199
I D+A Y A + RV + D+++ ACG I T +++IT LG+ E EE ++G
Sbjct: 297 IDDLAQYYLAKAGILAVRRVKQSDIEKIAKACGAKIITDLREITSADLGEAELVEERKVG 356
Query: 200 GERFNIFVGCPEAKTCTIILRGGSEQFMEETERSLHDAIMIVRRAMKNDAVVAGGGAIDM 379
E+ GC K TI++RGGSE ++E ERSL DAI +V+ A+++ VVAGGGA ++
Sbjct: 357 DEKMVFIEGCKNPKAVTILIRGGSEHVVDEVERSLQDAIKVVKTALESGKVVAGGGAPEI 416
Query: 380 EISKYLRDYSRNIHGRDQQFIGAMARAFEVIPRQLCENAGFDATNILNKLRQKHAQGKIW 559
E++ +RD++ + GR+Q A A A EVIPR L EN+G D +IL +LR+ H +GK
Sbjct: 417 EVALKIRDWAPTLGGREQLAAEAFASALEVIPRALAENSGLDPIDILVELRKAHEEGKTT 476
Query: 560 CGVDIMNEDIADNFEACVWEPALVKSNAITAATEAACMVLTLDETIRN---AKSKTPE 724
GVD+ + ++A E V EP VK+ AIT+ATE A M+L +D+ I K K PE
Sbjct: 477 YGVDVFSGEVACMKERGVLEPLKVKTQAITSATEVAIMILRIDDVIAAKGLEKEKGPE 534
>sp|P48424|THSA_THEAC Thermosome alpha subunit (Thermosome subunit 1) (Chaperonin alpha
subunit)
Length = 545
Score = 175 bits (444), Expect = 1e-43
Identities = 91/240 (37%), Positives = 142/240 (59%)
Frame = +2
Query: 2 VLSKLPIGDVATQYFADRDMFCAGRVTEEDLKRTMAACGGAIQTTVKDITDDTLGKCESF 181
VL + I DVA Y A ++ RV + D+++ A G I T + D+T LG+ E+
Sbjct: 288 VLCQKGIDDVAQHYLAKEGIYAVRRVKKSDMEKLAKATGAKIVTDLDDLTPSVLGEAETV 347
Query: 182 EEVQIGGERFNIFVGCPEAKTCTIILRGGSEQFMEETERSLHDAIMIVRRAMKNDAVVAG 361
EE +IG +R +GC K +I++RGG++ + E ER+L+DAI +V ++ + G
Sbjct: 348 EERKIGDDRMTFVMGCKNPKAVSILIRGGTDHVVSEVERALNDAIRVVAITKEDGKFLWG 407
Query: 362 GGAIDMEISKYLRDYSRNIHGRDQQFIGAMARAFEVIPRQLCENAGFDATNILNKLRQKH 541
GGA++ E++ L Y+ ++ GR+Q I A A+A E+IPR L ENAG D N L KL+ +H
Sbjct: 408 GGAVEAELAMRLAKYANSVGGREQLAIEAFAKALEIIPRTLAENAGIDPINTLIKLKAEH 467
Query: 542 AQGKIWCGVDIMNEDIADNFEACVWEPALVKSNAITAATEAACMVLTLDETIRNAKSKTP 721
+G+I GVD+ N + D V +P VK++A+ +A E A M+L +D+ I + KS P
Sbjct: 468 EKGRISVGVDLDNNGVGDMKAKGVVDPLRVKTHALESAVEVATMILRIDDVIASKKSTPP 527
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,051,354
Number of Sequences: 369166
Number of extensions: 1795236
Number of successful extensions: 5789
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5224
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5441
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7907893860
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)