Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_E12
(864 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9GKI7|C43BP_BOVIN Goodpasture antigen-binding protein (... 154 3e-37
sp|Q9Y5P4|C43BP_HUMAN Goodpasture antigen-binding protein (... 154 4e-37
sp|Q9EQG9|C43BP_MOUSE Goodpasture antigen-binding protein (... 151 2e-36
sp|P06766|DPOLB_RAT DNA polymerase beta 35 0.35
sp|O57383|DPOLB_XENLA DNA polymerase beta 34 0.60
sp|Q8K409|DPOLB_MOUSE DNA polymerase beta 32 1.8
sp|P06746|DPOLB_HUMAN DNA polymerase beta 32 2.3
>sp|Q9GKI7|C43BP_BOVIN Goodpasture antigen-binding protein (GPBP) (Collagen type IV alpha
3 binding protein) (StAR-related lipid transfer protein
11) (StARD11) (START domain-containing protein 11)
Length = 624
Score = 154 bits (389), Expect = 3e-37
Identities = 80/188 (42%), Positives = 115/188 (61%), Gaps = 3/188 (1%)
Frame = +3
Query: 3 EICNYFWNVKHRMEWEITIDQPPTVLEYCGEDTVVLHQIYKRVWPTTQRDSVFWSHIREI 182
E+CNYFWNV R +WE TI+ V+E ++ ++++Q +KRVWP +QRD ++ S IR+I
Sbjct: 457 EVCNYFWNVDVRNDWETTIENFH-VVETLADNAIIIYQTHKRVWPASQRDVLYLSAIRKI 515
Query: 183 DNEQLASVCSIPPPSAERPYNMWLVMNYSTDYRAPQHTSA---NQLIRLILDVVLICQTI 353
P E W+V N+S D H+SA N+ +R ++V +ICQT+
Sbjct: 516 ------------PALNENDPETWIVCNFSVD-----HSSAPLNNRCVRAKINVAMICQTL 558
Query: 354 IEDEHGNPITSDVDINTVPRDRLKCKLLYASSVNPGGWAPASVLRTVARREYPRFIKRFS 533
+ GN + RD + CK+ Y ++VNPGGWAPASVLR VA+REYP+F+KRF+
Sbjct: 559 VSPPEGN--------QEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFT 610
Query: 534 QYVVEQTA 557
YV E+TA
Sbjct: 611 SYVQEKTA 618
>sp|Q9Y5P4|C43BP_HUMAN Goodpasture antigen-binding protein (GPBP) (Collagen type IV alpha
3 binding protein) (StAR-related lipid transfer protein
11) (StARD11) (START domain-containing protein 11)
Length = 624
Score = 154 bits (388), Expect = 4e-37
Identities = 79/186 (42%), Positives = 115/186 (61%), Gaps = 1/186 (0%)
Frame = +3
Query: 3 EICNYFWNVKHRMEWEITIDQPPTVLEYCGEDTVVLHQIYKRVWPTTQRDSVFWSHIREI 182
E+CNYFWNV R +WE TI+ V+E ++ ++++Q +KRVWP +QRD ++ S IR+I
Sbjct: 457 EVCNYFWNVDVRNDWETTIENFH-VVETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKI 515
Query: 183 DNEQLASVCSIPPPSAERPYNMWLVMNYSTDY-RAPQHTSANQLIRLILDVVLICQTIIE 359
P E W+V N+S D+ AP + N+ +R ++V +ICQT++
Sbjct: 516 ------------PALTENDPETWIVCNFSVDHDSAPLN---NRCVRAKINVAMICQTLVS 560
Query: 360 DEHGNPITSDVDINTVPRDRLKCKLLYASSVNPGGWAPASVLRTVARREYPRFIKRFSQY 539
GN + RD + CK+ Y ++VNPGGWAPASVLR VA+REYP+F+KRF+ Y
Sbjct: 561 PPEGN--------QEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSY 612
Query: 540 VVEQTA 557
V E+TA
Sbjct: 613 VQEKTA 618
>sp|Q9EQG9|C43BP_MOUSE Goodpasture antigen-binding protein (GPBP) (Collagen type IV alpha
3 binding protein) (StAR-related lipid transfer protein
11) (StARD11) (START domain-containing protein 11)
Length = 624
Score = 151 bits (382), Expect = 2e-36
Identities = 77/186 (41%), Positives = 115/186 (61%), Gaps = 1/186 (0%)
Frame = +3
Query: 3 EICNYFWNVKHRMEWEITIDQPPTVLEYCGEDTVVLHQIYKRVWPTTQRDSVFWSHIREI 182
E+CNYFWNV R +WE TI+ V+E ++ ++++Q +KRVWP +QRD ++ S IR+I
Sbjct: 457 EVCNYFWNVDVRNDWETTIENFH-VVETLADNAIIVYQTHKRVWPASQRDVLYLSAIRKI 515
Query: 183 DNEQLASVCSIPPPSAERPYNMWLVMNYSTDY-RAPQHTSANQLIRLILDVVLICQTIIE 359
P E W+V N+S D+ AP + N+ +R +++ +ICQT++
Sbjct: 516 ------------PALTENDPETWIVCNFSVDHDSAPLN---NRCVRAKINIAMICQTLVS 560
Query: 360 DEHGNPITSDVDINTVPRDRLKCKLLYASSVNPGGWAPASVLRTVARREYPRFIKRFSQY 539
G+ + RD + CK+ Y ++VNPGGWAPASVLR VA+REYP+F+KRF+ Y
Sbjct: 561 PPEGD--------QEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSY 612
Query: 540 VVEQTA 557
V E+TA
Sbjct: 613 VQEKTA 618
>sp|P06766|DPOLB_RAT DNA polymerase beta
Length = 335
Score = 34.7 bits (78), Expect = 0.35
Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 16/115 (13%)
Frame = +3
Query: 144 QRDSVFWSHIREIDNEQLASVCSIPPPSAERPYNMWLVMNY----STDYRAPQ--HTSAN 305
Q + + ++++D E +A+VC AE +M +++ + S + P+ H
Sbjct: 157 QMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVE 216
Query: 306 QL--IRLILDVVL--------ICQTIIEDEHGNPITSDVDINTVPRDRLKCKLLY 440
QL +R I D + +CQ E++ +DI +P+D+ C +LY
Sbjct: 217 QLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVLY 271
>sp|O57383|DPOLB_XENLA DNA polymerase beta
Length = 334
Score = 33.9 bits (76), Expect = 0.60
Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 15/114 (13%)
Frame = +3
Query: 144 QRDSVFWSHIREIDNEQLASVCSIPPPSAERPYNMWLVMNYS--TDYRAPQHTSANQLIR 317
Q + + +D E +A+VC AE +M +++ + T A Q +Q+++
Sbjct: 157 QMQEIILDKVNNLDPEYIATVCGSFRRGAESSGDMDILLTHPDFTSESAKQPRLLHQVVQ 216
Query: 318 LILDVVLICQTIIEDEHGN------PITSD-------VDINTVPRDRLKCKLLY 440
+ D I T+++ + P SD +DI +P+D+ C +LY
Sbjct: 217 CLEDCNFITDTLVKGDTKFMGVCQLPCESDQDYPYRRIDIRLIPKDQYYCGVLY 270
>sp|Q8K409|DPOLB_MOUSE DNA polymerase beta
Length = 335
Score = 32.3 bits (72), Expect = 1.8
Identities = 27/115 (23%), Positives = 51/115 (44%), Gaps = 16/115 (13%)
Frame = +3
Query: 144 QRDSVFWSHIREIDNEQLASVCSIPPPSAERPYNMWLVMNY----STDYRAPQ--HTSAN 305
Q + + I+++D+E +A+VC AE +M +++ + S + P+ H
Sbjct: 157 QMQDIVLNEIKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVE 216
Query: 306 QL--IRLILDVVL--------ICQTIIEDEHGNPITSDVDINTVPRDRLKCKLLY 440
QL + I D + +CQ E + +DI +P+D+ C +LY
Sbjct: 217 QLQKVHFITDTLSKGETKFMGVCQLPSEKDGKEYPHRRIDIRLIPKDQYYCGVLY 271
>sp|P06746|DPOLB_HUMAN DNA polymerase beta
Length = 335
Score = 32.0 bits (71), Expect = 2.3
Identities = 25/115 (21%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Frame = +3
Query: 144 QRDSVFWSHIREIDNEQLASVCSIPPPSAERPYNMWLVMNY------STDYRAPQHTSAN 305
Q + + ++++D+E +A+VC AE +M +++ + ST H
Sbjct: 157 QMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVE 216
Query: 306 QL--IRLILDVVL--------ICQTIIEDEHGNPITSDVDINTVPRDRLKCKLLY 440
QL + I D + +CQ +++ +DI +P+D+ C +LY
Sbjct: 217 QLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLY 271
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,283,606
Number of Sequences: 369166
Number of extensions: 1890058
Number of successful extensions: 4458
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4320
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4442
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8582957970
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)