Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_E03
(758 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8WW22|DNJA4_HUMAN DnaJ homolog subfamily A member 4 151 2e-36
sp|Q9JMC3|DNJA4_MOUSE DnaJ homolog subfamily A member 4 (Mm... 149 8e-36
sp|P31689|DNJA1_HUMAN DnaJ homolog subfamily A member 1 (He... 148 2e-35
sp|P63036|DNJA1_RAT DnaJ homolog subfamily A member 1 (DnaJ... 148 2e-35
sp|P42824|DNJH2_ALLPO DnaJ protein homolog 2 135 9e-32
sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (DNAJ-1) 132 1e-30
sp|O60884|DNJA2_HUMAN DnaJ homolog subfamily A member 2 (HI... 130 3e-30
sp|Q9QYJ0|DNJA2_MOUSE DnaJ homolog subfamily A member 2 (mDj3) 129 7e-30
sp|Q94AW8|DNAJ3_ARATH Chaperone protein dnaJ 3 (AtJ3) (AtDjA3) 128 2e-29
sp|O35824|DNJA2_RAT DnaJ homolog subfamily A member 2 (RDJ2) 127 2e-29
>sp|Q8WW22|DNJA4_HUMAN DnaJ homolog subfamily A member 4
Length = 397
Score = 151 bits (382), Expect = 2e-36
Identities = 81/175 (46%), Positives = 114/175 (65%)
Frame = +1
Query: 1 PGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKP 180
P LEPGD+ IVL++K H+VF R+ DLI MK+ L ++LCGFK+TI TLDNRILV+ +K
Sbjct: 233 PELEPGDVIIVLDQKDHSVFQRRGHDLIMKMKIQLSEALCGFKKTIKTLDNRILVITSKA 292
Query: 181 GEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQF 360
GEVIK+ + R + +EGMP YK+P E+G LIIQF V+FPE ++L +KL +L ++LPP Q
Sbjct: 293 GEVIKHGDLRCVRDEGMPIYKAPLEKGILIIQFLVIFPEKHWLSLEKLPQLEALLPPRQK 352
Query: 361 SSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQC 525
D+M + E L + P+ N + + Y+ D++G G VQC
Sbjct: 353 VRITDDMDQVE---LKEFCPNEQN------WRQHREAYEEDEDGPQAG----VQC 394
>sp|Q9JMC3|DNJA4_MOUSE DnaJ homolog subfamily A member 4 (MmDjA4)
Length = 397
Score = 149 bits (376), Expect = 8e-36
Identities = 79/175 (45%), Positives = 113/175 (64%)
Frame = +1
Query: 1 PGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKP 180
P L+PGD+ IVL++K H+VF R+ DLI MK+ L ++LCGFK+TI TLD+R+LV+ +K
Sbjct: 233 PELDPGDVIIVLDQKDHSVFQRRGQDLIMKMKIQLSEALCGFKKTIKTLDDRVLVISSKS 292
Query: 181 GEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQF 360
GEVIK+ + + I NEGMP YK+P E+G +IIQF VVFPE +L +KL +L ++LPP Q
Sbjct: 293 GEVIKHGDLKCIRNEGMPIYKAPLEKGVMIIQFLVVFPEKQWLSQEKLPQLEALLPPRQK 352
Query: 361 SSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQC 525
D+M + E L ++P ++ + + Y+ DDE G VQC
Sbjct: 353 VRITDDMDQVE---LKEFNP------NEQSWRQHREAYEEDDEEPRAG----VQC 394
>sp|P31689|DNJA1_HUMAN DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4)
(DnaJ protein homolog 2) (HSJ-2) (HSDJ)
Length = 397
Score = 148 bits (373), Expect = 2e-35
Identities = 78/171 (45%), Positives = 109/171 (63%)
Frame = +1
Query: 1 PGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKP 180
PGLEPGDI IVL++K H VFTR+ DL M + LV++LCGF++ I+TLDNR +V+ + P
Sbjct: 232 PGLEPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHP 291
Query: 181 GEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQF 360
G+++K+ + + + NEGMP Y+ P+E+GRLII+F V FPEN FL DKL+ L +LP +
Sbjct: 292 GQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKE 351
Query: 361 SSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQ 513
D M + E L +DP+ + R H Y+ DDE GG Q
Sbjct: 352 VEETDEMDQVE---LVDFDPN-----QERRRHYNGEAYE-DDEHHPRGGVQ 393
>sp|P63036|DNJA1_RAT DnaJ homolog subfamily A member 1 (DnaJ-like protein 1)
sp|P63037|DNJA1_MOUSE DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4)
(DnaJ protein homolog 2) (HSJ-2)
Length = 397
Score = 148 bits (373), Expect = 2e-35
Identities = 78/171 (45%), Positives = 109/171 (63%)
Frame = +1
Query: 1 PGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKP 180
PGLEPGDI IVL++K H VFTR+ DL M + LV++LCGF++ I+TLDNR +V+ + P
Sbjct: 232 PGLEPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHP 291
Query: 181 GEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQF 360
G+++K+ + + + NEGMP Y+ P+E+GRLII+F V FPEN FL DKL+ L +LP +
Sbjct: 292 GQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKE 351
Query: 361 SSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQ 513
D M + E L +DP+ + R H Y+ DDE GG Q
Sbjct: 352 VEETDEMDQVE---LVDFDPN-----QERRRHYNGEAYE-DDEHHPRGGVQ 393
>sp|P42824|DNJH2_ALLPO DnaJ protein homolog 2
Length = 418
Score = 135 bits (341), Expect = 9e-32
Identities = 77/178 (43%), Positives = 110/178 (61%), Gaps = 2/178 (1%)
Frame = +1
Query: 1 PGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKP 180
P GDI VL++K H F RK DL Y L L ++LCGF+ +T LDNR L++++ P
Sbjct: 246 PDTVTGDIVFVLQQKEHPKFKRKGDDLFYEHSLSLTEALCGFQFVLTHLDNRQLLIKSNP 305
Query: 181 GEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQF 360
GEVIK +++ I++EGMP Y+ PF +G+L I F V FP++ L D+ L S+L PS+
Sbjct: 306 GEVIKPDQFKGINDEGMPMYQRPFMRGKLYIHFSVDFPDS--LTPDQCKALESVL-PSRN 362
Query: 361 SSSLDNMK--EAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQCA 528
+S L +M+ E EE +H D ++ + ++ + YD DDEG GGAQRVQCA
Sbjct: 363 ASRLTDMEIDECEETTMH--DVNIEEEMRRKQHQQAQEAYDEDDEG--HGGAQRVQCA 416
>sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (DNAJ-1)
Length = 397
Score = 132 bits (332), Expect = 1e-30
Identities = 74/177 (41%), Positives = 105/177 (59%), Gaps = 1/177 (0%)
Frame = +1
Query: 1 PGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKP 180
P GDI VL++K H F RK DL Y L L ++LCGF+ +T LD R L++++ P
Sbjct: 225 PDTVTGDIVFVLQQKEHPKFQRKGDDLFYKHTLSLTEALCGFQFVLTHLDGRQLLIKSNP 284
Query: 181 GEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQF 360
GEV+K +++AI++EGMP Y+ PF +G+L IQF V FP++ L D+ + S+LP S
Sbjct: 285 GEVVKPDQFKAINDEGMPMYQRPFMRGKLYIQFLVDFPDS--LTPDQCKVIESVLPRSAS 342
Query: 361 SSSLD-NMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQCA 528
S D + E EE +H D ++ + ++ YD DDEG GG QRVQCA
Sbjct: 343 SQLTDMEIDECEETTMH--DVNIEEEMRRKQHQHAQEAYDEDDEG--HGGGQRVQCA 395
>sp|O60884|DNJA2_HUMAN DnaJ homolog subfamily A member 2 (HIRA interacting protein 4)
(Cell cycle progression restoration gene 3 protein)
(Dnj3)
Length = 412
Score = 130 bits (328), Expect = 3e-30
Identities = 74/176 (42%), Positives = 103/176 (58%)
Frame = +1
Query: 1 PGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKP 180
PG+EPGDI ++L+EK H VF R DL K+ LV++LCGF+ T LD R +VV+ P
Sbjct: 241 PGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDGRQIVVKYPP 300
Query: 181 GEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQF 360
G+VI+ R + EGMP+Y++PFE+G L I+FDV FPENN++ DKL++L +LP
Sbjct: 301 GKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPE 360
Query: 361 SSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQCA 528
++ + E EE L +D + + Q R DS DE VQCA
Sbjct: 361 VPNI--IGETEEVELQEFDSTRGSGGGQ----RREAYNDSSDEESSSHHGPGVQCA 410
>sp|Q9QYJ0|DNJA2_MOUSE DnaJ homolog subfamily A member 2 (mDj3)
Length = 412
Score = 129 bits (325), Expect = 7e-30
Identities = 74/176 (42%), Positives = 103/176 (58%)
Frame = +1
Query: 1 PGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKP 180
PG+EPGDI ++L+EK H VF R DL K+ LV++LCGF+ T LD R +VV+ P
Sbjct: 241 PGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDARQIVVKYPP 300
Query: 181 GEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQF 360
G+VI+ R + EGMP+Y++PFE+G L I+FDV FPENN++ DKL++L +LP
Sbjct: 301 GKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPE 360
Query: 361 SSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQCA 528
++ + E EE L +D + + Q R DS DE VQCA
Sbjct: 361 VPNV--IGETEEVELQEFDSTRGSGGGQ----RREAYNDSSDEESSSHHGPGVQCA 410
>sp|Q94AW8|DNAJ3_ARATH Chaperone protein dnaJ 3 (AtJ3) (AtDjA3)
Length = 420
Score = 128 bits (321), Expect = 2e-29
Identities = 73/177 (41%), Positives = 102/177 (57%), Gaps = 1/177 (0%)
Frame = +1
Query: 1 PGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKP 180
P GDI VL++K H F RK DL L L ++LCGF+ +T LD R L++++ P
Sbjct: 246 PDTVTGDIVFVLQQKEHPKFKRKGEDLFVEHTLSLTEALCGFQFVLTHLDGRSLLIKSNP 305
Query: 181 GEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILP-PSQ 357
GEV+K Y+AI +EGMP Y+ PF +G+L I F V FP++ L D+ L ++LP PS
Sbjct: 306 GEVVKPDSYKAISDEGMPIYQRPFMKGKLYIHFTVEFPDS--LSPDQTKALEAVLPKPST 363
Query: 358 FSSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQCA 528
S + E EE LH D ++ + + +R D D++ PGGAQRVQCA
Sbjct: 364 AQLSDMEIDECEETTLH--DVNIEDEMRRKAQAQREAYDDDDEDDDHPGGAQRVQCA 418
>sp|O35824|DNJA2_RAT DnaJ homolog subfamily A member 2 (RDJ2)
Length = 412
Score = 127 bits (320), Expect = 2e-29
Identities = 73/176 (41%), Positives = 102/176 (57%)
Frame = +1
Query: 1 PGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKP 180
PG+EPGDI + ++EK H VF R DL K+ LV++LCGF+ T LD R +VV+ P
Sbjct: 241 PGVEPGDIVLFVQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDARQIVVKYPP 300
Query: 181 GEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQF 360
G+VI+ R + EGMP+Y++PFE+G L I+FDV FPENN++ DKL++L +LP
Sbjct: 301 GKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPE 360
Query: 361 SSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQCA 528
++ + E EE L +D + + Q R DS DE VQCA
Sbjct: 361 VPNV--IGETEEVELQEFDSTRGSGGGQ----RREAYNDSSDEESSSHHGPGVQCA 410
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,221,170
Number of Sequences: 369166
Number of extensions: 1512113
Number of successful extensions: 4352
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4195
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4325
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6970118400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)