Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_C19
(243 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P02566|MYO4_CAEEL Myosin-4 (Myosin heavy chain B) (MHC B... 43 3e-04
sp|P12845|MYO2_CAEEL Myosin-2 (Myosin heavy chain C) (MHC C) 41 8e-04
sp|P12844|MYO3_CAEEL Myosin-3 (Myosin heavy chain A) (MHC A) 41 8e-04
sp|Q8VDD5|MYH9_MOUSE Myosin-9 (Myosin heavy chain, nonmuscl... 40 0.001
sp|Q62812|MYH9_RAT Myosin-9 (Myosin heavy chain, nonmuscle ... 40 0.002
sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscl... 40 0.002
sp|P33420|NIP80_YEAST Protein NIP80 (Protein NIP100) 39 0.005
sp|P05661|MYSA_DROME Myosin heavy chain, muscle 39 0.005
sp|P12847|MYH3_RAT Myosin heavy chain, fast skeletal muscle... 38 0.006
sp|Q59037|SMC_METJA Chromosome partition protein smc homolog 38 0.006
>sp|P02566|MYO4_CAEEL Myosin-4 (Myosin heavy chain B) (MHC B) (Uncoordinated protein 54)
Length = 1966
Score = 42.7 bits (99), Expect = 3e-04
Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 7/79 (8%)
Frame = +3
Query: 9 SKQIENLEDEL-------ECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREV 167
S++I++L D+L K I++L+ EK+EL+ L+ L E + ++ EV
Sbjct: 1518 SQEIKDLTDQLGEGGRSVHEMQKIIRRLEIEKEELQHALDEAEAALEAEESKVLRAQVEV 1577
Query: 168 SELRDEYQIRIRKKLDEYE 224
S++R E + RI++K +E+E
Sbjct: 1578 SQIRSEIEKRIQEKEEEFE 1596
Score = 34.3 bits (77), Expect = 0.092
Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 7/69 (10%)
Frame = +3
Query: 6 ASKQIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQH-------LNRAEDQACKSARE 164
ASKQ+ L D+L + + +Q K ++EA++E L++ L +AE + +
Sbjct: 927 ASKQLSELNDQLADNEDRTADVQRAKKKIEAEVEALKKQIQDLEMSLRKAESEKQSKDHQ 986
Query: 165 VSELRDEYQ 191
+ L+DE Q
Sbjct: 987 IRSLQDEMQ 995
Score = 28.1 bits (61), Expect = 6.6
Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 7/82 (8%)
Frame = +3
Query: 15 QIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQA-------CKSAREVSE 173
QI +L+DE++ + I +L EK E L + L ED+ K + + +
Sbjct: 986 QIRSLQDEMQQQDEAIAKLNKEKKHQEEINRKLMEDLQSEEDKGNHQNKVKAKLEQTLDD 1045
Query: 174 LRDEYQIRIRKKLDEYELDKER 239
L D + R+K +LDK++
Sbjct: 1046 LEDSLE---REKRARADLDKQK 1064
Score = 27.7 bits (60), Expect = 8.6
Identities = 13/49 (26%), Positives = 26/49 (53%)
Frame = +3
Query: 12 KQIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSA 158
KQ+E E+ +L+K KQL + ++ E + + L++ ++ SA
Sbjct: 1892 KQVEEAEELANLNLQKYKQLTHQLEDAEERADQAENSLSKMRSKSRASA 1940
>sp|P12845|MYO2_CAEEL Myosin-2 (Myosin heavy chain C) (MHC C)
Length = 1947
Score = 41.2 bits (95), Expect = 8e-04
Identities = 20/57 (35%), Positives = 35/57 (61%)
Frame = +3
Query: 54 KKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRDEYQIRIRKKLDEYE 224
K +++L+ EK+EL+ L+ L E +A + EVS++R E + RI +K +E+E
Sbjct: 1544 KNLRRLEMEKEELQRGLDEAEAALESEESKALRCQIEVSQIRAEIEKRIAEKEEEFE 1600
Score = 34.7 bits (78), Expect = 0.070
Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +3
Query: 15 QIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKS----AREVSELRD 182
QI L+DE+ + I +L E+ E Q + L + L AE+Q + A+ + L D
Sbjct: 990 QIRALQDEMRQQDENISKLNKERKNQEEQNKKLTEDLQAAEEQNLAANKLKAKLMQSLED 1049
Query: 183 EYQIRIRKKLDEYELDKER 239
Q R+K + ++DK +
Sbjct: 1050 SEQTMEREKRNRADMDKNK 1068
>sp|P12844|MYO3_CAEEL Myosin-3 (Myosin heavy chain A) (MHC A)
Length = 1969
Score = 41.2 bits (95), Expect = 8e-04
Identities = 24/79 (30%), Positives = 48/79 (60%), Gaps = 7/79 (8%)
Frame = +3
Query: 9 SKQIENLEDELE------CSLKKI-KQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREV 167
++++++L D+L L+KI ++L+ EK+EL+ L+ L E + ++ EV
Sbjct: 1519 AQEVKDLTDQLGEGGRSVAELQKIVRKLEVEKEELQKALDEAEAALEAEEAKVLRAQIEV 1578
Query: 168 SELRDEYQIRIRKKLDEYE 224
S++R E + RI++K +E+E
Sbjct: 1579 SQIRSEIEKRIQEKEEEFE 1597
>sp|Q8VDD5|MYH9_MOUSE Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1960
Score = 40.4 bits (93), Expect = 0.001
Identities = 26/77 (33%), Positives = 38/77 (49%)
Frame = +3
Query: 3 KASKQIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRD 182
K + I+ LE++LE ++LQ EK EA+L+ L + EDQ CK A+E L D
Sbjct: 940 KMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLED 999
Query: 183 EYQIRIRKKLDEYELDK 233
++E E K
Sbjct: 1000 RVAEFTTNLMEEEEKSK 1016
Score = 35.8 bits (81), Expect = 0.032
Identities = 22/78 (28%), Positives = 38/78 (48%)
Frame = +3
Query: 6 ASKQIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRDE 185
A ++E + +LKKI++L+ + EL+ LE R N+AE Q E+ L+ E
Sbjct: 1088 ALARVEEEAAQKNMALKKIRELETQISELQEDLESERASRNKAEKQKRDLGEELEALKTE 1147
Query: 186 YQIRIRKKLDEYELDKER 239
+ + + EL +R
Sbjct: 1148 LEDTLDSTAAQQELRSKR 1165
Score = 30.0 bits (66), Expect = 1.7
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 10/77 (12%)
Frame = +3
Query: 15 QIENLEDELECS----LKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREV-SELR 179
Q+E LEDEL+ + L+ LQ K + E L+ + + Q + RE+ +EL
Sbjct: 1540 QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELE 1599
Query: 180 DEYQIR-----IRKKLD 215
DE + R RKKL+
Sbjct: 1600 DERKQRSMAMAARKKLE 1616
Score = 28.5 bits (62), Expect = 5.0
Identities = 18/74 (24%), Positives = 38/74 (51%)
Frame = +3
Query: 12 KQIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRDEYQ 191
+++E L+ ELE +L Q + + E ++ L++ L ED+A ++ E+R ++
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVSILKKTL---EDEAKTHEAQIQEMRQKHS 1195
Query: 192 IRIRKKLDEYELDK 233
+ + D+ E K
Sbjct: 1196 QAVEELADQLEQTK 1209
>sp|Q62812|MYH9_RAT Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1961
Score = 40.0 bits (92), Expect = 0.002
Identities = 26/77 (33%), Positives = 38/77 (49%)
Frame = +3
Query: 3 KASKQIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRD 182
K + I+ LE++LE ++LQ EK EA+L+ L + EDQ CK A+E L D
Sbjct: 940 KMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLED 999
Query: 183 EYQIRIRKKLDEYELDK 233
++E E K
Sbjct: 1000 RVAEFTTDLMEEEEKSK 1016
Score = 35.0 bits (79), Expect = 0.054
Identities = 22/78 (28%), Positives = 38/78 (48%)
Frame = +3
Query: 6 ASKQIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRDE 185
A ++E + +LKKI++L+ + EL+ LE R N+AE Q E+ L+ E
Sbjct: 1088 ALARVEEEAAQKNMALKKIRELETQISELQEDLESERACRNKAEKQKRDLGEELEALKTE 1147
Query: 186 YQIRIRKKLDEYELDKER 239
+ + + EL +R
Sbjct: 1148 LEDTLDSTAAQQELRSKR 1165
Score = 30.0 bits (66), Expect = 1.7
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 10/77 (12%)
Frame = +3
Query: 15 QIENLEDELECS----LKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREV-SELR 179
Q+E LEDEL+ + L+ LQ K + E L+ + + Q + RE+ +EL
Sbjct: 1541 QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELE 1600
Query: 180 DEYQIR-----IRKKLD 215
DE + R RKKL+
Sbjct: 1601 DERKQRSIAMAARKKLE 1617
>sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1960
Score = 39.7 bits (91), Expect = 0.002
Identities = 23/60 (38%), Positives = 33/60 (55%)
Frame = +3
Query: 3 KASKQIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRD 182
K + I+ LE++LE ++LQ EK EA+L+ L + EDQ CK A+E L D
Sbjct: 940 KMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLED 999
Score = 35.8 bits (81), Expect = 0.032
Identities = 22/78 (28%), Positives = 38/78 (48%)
Frame = +3
Query: 6 ASKQIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRDE 185
A ++E + +LKKI++L+ + EL+ LE R N+AE Q E+ L+ E
Sbjct: 1088 ALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTE 1147
Query: 186 YQIRIRKKLDEYELDKER 239
+ + + EL +R
Sbjct: 1148 LEDTLDSTAAQQELRSKR 1165
Score = 30.0 bits (66), Expect = 1.7
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 10/77 (12%)
Frame = +3
Query: 15 QIENLEDELECS----LKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREV-SELR 179
Q+E LEDEL+ + L+ LQ K + E L+ + + Q + RE+ +EL
Sbjct: 1540 QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELE 1599
Query: 180 DEYQ-----IRIRKKLD 215
DE + + RKKL+
Sbjct: 1600 DERKQRSMAVAARKKLE 1616
>sp|P33420|NIP80_YEAST Protein NIP80 (Protein NIP100)
Length = 868
Score = 38.5 bits (88), Expect = 0.005
Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 15/91 (16%)
Frame = +3
Query: 15 QIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRDE--- 185
Q EN+ ELE +K I E+ LE ++ L+ LN ++ C +++L++E
Sbjct: 664 QKENMLTELETKIKIIIGRDLERKTLEENIKTLKVELNNKNEENCGKTEILNKLKEENFN 723
Query: 186 ------------YQIRIRKKLDEYELDKERV 242
YQI+ L++ LD+E+V
Sbjct: 724 LVNRLKNMELKLYQIKDNNTLNKIYLDREKV 754
>sp|P05661|MYSA_DROME Myosin heavy chain, muscle
Length = 1962
Score = 38.5 bits (88), Expect = 0.005
Identities = 28/74 (37%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Frame = +3
Query: 27 LEDELECSLK---KIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRDEYQIR 197
LEDE LK +IK+LQ +ELE ++E RQ +AE Q ARE+ EL + +
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEELGERLEEA 1152
Query: 198 IRKKLDEYELDKER 239
+ EL+K+R
Sbjct: 1153 GGATSAQIELNKKR 1166
>sp|P12847|MYH3_RAT Myosin heavy chain, fast skeletal muscle, embryonic
Length = 1940
Score = 38.1 bits (87), Expect = 0.006
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Frame = +3
Query: 27 LEDELECSL---KKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRDEYQIR 197
+EDE SL KKIK+LQ +ELE ++E R + E Q ARE+ EL + +
Sbjct: 1095 VEDEQTLSLQLQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEA 1154
Query: 198 IRKKLDEYELDKER 239
+ EL+K+R
Sbjct: 1155 GGVTSTQIELNKKR 1168
>sp|Q59037|SMC_METJA Chromosome partition protein smc homolog
Length = 1169
Score = 38.1 bits (87), Expect = 0.006
Identities = 22/61 (36%), Positives = 38/61 (62%)
Frame = +3
Query: 15 QIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRDEYQI 194
++ENL E+E S + IK+L+ +K EL+A+L+ L + E+ K+ +E+ EL + I
Sbjct: 456 ELENLNVEIEFSKRGIKELEEKKKELQAKLDELHAEYVK-ENARIKALKEMEELSMDRAI 514
Query: 195 R 197
R
Sbjct: 515 R 515
Score = 30.8 bits (68), Expect = 1.0
Identities = 19/76 (25%), Positives = 44/76 (57%)
Frame = +3
Query: 15 QIENLEDELECSLKKIKQLQFEKDELEAQLEHLRQHLNRAEDQACKSAREVSELRDEYQI 194
++ +++E+E K +K+ +K E+E LE ++++ R + A K+ ++ EL + +
Sbjct: 691 ELRKIKEEIERLSKIVKRSSAKKMEIENTLEIIKKNEMRKREIAEKNTIKIKELELKNK- 749
Query: 195 RIRKKLDEYELDKERV 242
I ++L+E L +E +
Sbjct: 750 DILEELEELNLKREEI 765
Score = 28.9 bits (63), Expect = 3.9
Identities = 18/59 (30%), Positives = 33/59 (55%), Gaps = 7/59 (11%)
Frame = +3
Query: 30 EDELECSLKKIKQLQFEKDELE---AQLEHLRQHLNRAE----DQACKSAREVSELRDE 185
E +++ +KIK L +EK+ L+ A+ E + +HL +E D+ K+ E+ L+ E
Sbjct: 355 EQQIKEIEEKIKNLNYEKERLKEAIAESESIIKHLKESEMEIADEIAKNQNELYRLKKE 413
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,400,250
Number of Sequences: 369166
Number of extensions: 178997
Number of successful extensions: 3534
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2919
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3495
length of database: 68,354,980
effective HSP length: 51
effective length of database: 58,933,495
effective search space used: 1709071355
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)