Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_C17
(589 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P25037|UBP1_YEAST Ubiquitin carboxyl-terminal hydrolase ... 35 0.18
sp|P40214|YM22_YEAST Hypothetical 38.6 kDa protein in RPS16... 34 0.31
sp|P26884|FKBP3_BOVIN FK506-binding protein 3 (Peptidyl-pro... 33 0.69
sp|Q00688|FKBP3_HUMAN FK506-binding protein 3 (Peptidyl-pro... 32 0.90
sp|P06778|RAD52_YEAST DNA repair and recombination protein ... 32 0.90
sp|Q10328|YD73_SCHPO Hypothetical protein C32A11.03c in chr... 32 0.90
sp|P05184|CP3A3_HUMAN Cytochrome P450 3A3 (CYPIIIA3) (HLp) 32 1.2
sp|P47134|BIR1_YEAST Protein BIR1 32 1.2
sp|O46638|FKBP3_RABIT FK506-binding protein 3 (Peptidyl-pro... 32 1.5
sp|Q62446|FKBP3_MOUSE FK506-binding protein 3 (Peptidyl-pro... 31 2.6
>sp|P25037|UBP1_YEAST Ubiquitin carboxyl-terminal hydrolase 1 (Ubiquitin thiolesterase 1)
(Ubiquitin-specific processing protease 1)
(Deubiquitinating enzyme 1)
Length = 809
Score = 34.7 bits (78), Expect = 0.18
Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 16/126 (12%)
Frame = +1
Query: 70 DKPTWKKSECTRTITSSILKAIKKMPESSV---------REYFKNKKEIIKRISNHKPEN 222
DKP +K T+S+LKA+ K P ++ +E+F+N I+ + ++
Sbjct: 217 DKPYFK--------TNSLLKAMSKSPRKNILLGYDQEDAQEFFQN---ILAELESNVKSL 265
Query: 223 EMEILKAILNIASELNKDTLTLIYDL-------LFTEGIISNTVLKTYLNDKSLQSESNF 381
E L SEL D L +L + TE I N++L +DKS+Q+ + F
Sbjct: 266 NTEKLDTTPVAKSELPDDALVGQLNLGEVGTVYIPTEQIDPNSIL----HDKSIQNFTPF 321
Query: 382 KLTSPI 399
KL +P+
Sbjct: 322 KLMTPL 327
>sp|P40214|YM22_YEAST Hypothetical 38.6 kDa protein in RPS16A-TIF34 intergenic region
Length = 342
Score = 33.9 bits (76), Expect = 0.31
Identities = 35/152 (23%), Positives = 71/152 (46%), Gaps = 9/152 (5%)
Frame = +1
Query: 13 MLSSNSSNENIFDFLENHVDKPTWKKSECTRTITSSILKAIKKMPESSVREYF-----KN 177
+L+SN +N +E+++ K +++ +C + LK + E+ + +Y KN
Sbjct: 144 ILTSNENNIQSRHEVEDNLQKQQFERMKCQFLLERQSLKDQLRKRENKIVKYKQKIIEKN 203
Query: 178 KK--EIIKRISNHKPENEMEILKAILNIASELNKDTLT--LIYDLLFTEGIISNTVLKTY 345
KK + K ++ H + +I ++ + T + D+L T GI++ VLK
Sbjct: 204 KKLNNLAKVLNQHAISDTSQIDSFSSSVKKTPSSTTTPQEMKSDMLNTLGILATHVLKDE 263
Query: 346 LNDKSLQSESNFKLTSPILSNMCVIR*LNYFC 441
++D S +++ +L + +SN C L C
Sbjct: 264 IDDDS-GNQTILQLAAGSISNDCNTTELEITC 294
>sp|P26884|FKBP3_BOVIN FK506-binding protein 3 (Peptidyl-prolyl cis-trans isomerase)
(PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25)
(Rapamycin-selective 25 kDa immunophilin)
Length = 224
Score = 32.7 bits (73), Expect = 0.69
Identities = 28/79 (35%), Positives = 41/79 (51%), Gaps = 13/79 (16%)
Frame = +1
Query: 178 KKEIIKRISNHKPEN---EMEILKAILNIASELNKDTLTLIYDLLF-------TEGI--I 321
KK+IIK + +H ++ E ++L I N+A NKD L Y+ LF TE I +
Sbjct: 22 KKDIIKFLQDHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFESKRFKGTESISKV 81
Query: 322 SNTVLKTYLN-DKSLQSES 375
S V LN DK +++S
Sbjct: 82 SEQVKNVKLNEDKPKETKS 100
>sp|Q00688|FKBP3_HUMAN FK506-binding protein 3 (Peptidyl-prolyl cis-trans isomerase)
(PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25)
(Rapamycin-selective 25 kDa immunophilin)
Length = 224
Score = 32.3 bits (72), Expect = 0.90
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 13/79 (16%)
Frame = +1
Query: 178 KKEIIKRISNHKPEN---EMEILKAILNIASELNKDTLTLIYDLLF-------TEGI--I 321
KK+IIK + H ++ E ++L I N+A NKD L Y+ LF TE I +
Sbjct: 22 KKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFETKRFKGTESISKV 81
Query: 322 SNTVLKTYLN-DKSLQSES 375
S V LN DK +++S
Sbjct: 82 SEQVKNVKLNEDKPKETKS 100
>sp|P06778|RAD52_YEAST DNA repair and recombination protein RAD52
Length = 504
Score = 32.3 bits (72), Expect = 0.90
Identities = 17/64 (26%), Positives = 36/64 (56%)
Frame = +1
Query: 49 DFLENHVDKPTWKKSECTRTITSSILKAIKKMPESSVREYFKNKKEIIKRISNHKPENEM 228
DF EN++ +PT + SE +RT T + E+ ++ + NK+ + +++N P++
Sbjct: 199 DFDENNLFRPTDEISESSRTNT---------LHENQEQQQYPNKRRQLTKVTNTNPDSTK 249
Query: 229 EILK 240
++K
Sbjct: 250 NLVK 253
>sp|Q10328|YD73_SCHPO Hypothetical protein C32A11.03c in chromosome I
Length = 942
Score = 32.3 bits (72), Expect = 0.90
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Frame = +1
Query: 142 MPESSVREYFKNKKEIIKRISNHKPENEMEILKAILNIASELNKDTLTLIYDLLFTE--- 312
+PE SV +F+N++ K IS + E IL+ + S K + +++L T
Sbjct: 205 IPERSVTIWFQNRRAKSKLISRRQEEERQRILREQRELDSLNQKVSQAFAHEVLSTSPTS 264
Query: 313 ----GIISNTVLKTYLNDKSLQSESNFKLTS-PILSNM 411
GI +N L K + NF + S P+ S+M
Sbjct: 265 PYVGGIAANRQYANTLLPKPTRKTGNFYMKSGPMQSSM 302
>sp|P05184|CP3A3_HUMAN Cytochrome P450 3A3 (CYPIIIA3) (HLp)
Length = 504
Score = 32.0 bits (71), Expect = 1.2
Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Frame = +1
Query: 103 RTITSSILKAIKKMPESSVREYFKNKKEIIK-RISNHKPENEMEILKAILNIASELNKDT 279
R +T+ + KA+K+M ES + + K++ + ++ I +HK E E KA+ ++ EL +
Sbjct: 243 REVTNFLRKAVKRMKESRLEDTQKHRVDFLQLMIDSHKNSKETESHKALSDL--ELVAQS 300
Query: 280 LTLIY 294
+ I+
Sbjct: 301 IIFIF 305
>sp|P47134|BIR1_YEAST Protein BIR1
Length = 954
Score = 32.0 bits (71), Expect = 1.2
Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 5/55 (9%)
Frame = +1
Query: 124 LKAIKKMPESSVREYFKNKKEIIK-----RISNHKPENEMEILKAILNIASELNK 273
L +KK E+ +YF NK+E IK + N P NEM + + IAS+ NK
Sbjct: 703 LSGLKK--ETDDGKYFTNKQETIKILEDVSVKNETPNNEMLLFETGTPIASQENK 755
>sp|O46638|FKBP3_RABIT FK506-binding protein 3 (Peptidyl-prolyl cis-trans isomerase)
(PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25)
(Rapamycin-selective 25 kDa immunophilin)
Length = 223
Score = 31.6 bits (70), Expect = 1.5
Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 3/46 (6%)
Frame = +1
Query: 178 KKEIIKRISNHKPEN---EMEILKAILNIASELNKDTLTLIYDLLF 306
KK+IIK + +H ++ E ++L I N+A NKD L Y+ LF
Sbjct: 21 KKDIIKFLQDHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLF 66
>sp|Q62446|FKBP3_MOUSE FK506-binding protein 3 (Peptidyl-prolyl cis-trans isomerase)
(PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25)
(Rapamycin-selective 25 kDa immunophilin)
Length = 224
Score = 30.8 bits (68), Expect = 2.6
Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 3/46 (6%)
Frame = +1
Query: 178 KKEIIKRISNHKPEN---EMEILKAILNIASELNKDTLTLIYDLLF 306
KK+IIK + +H ++ E ++L I N+A NKD L Y+ LF
Sbjct: 22 KKDIIKFLQDHGSDSFLAEHKLLGNIKNVAKTANKDHLVNAYNHLF 67
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,908,119
Number of Sequences: 369166
Number of extensions: 990279
Number of successful extensions: 3189
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3118
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3186
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4406202450
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)