Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_B08
(845 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P42694|HELZ_HUMAN Probable helicase with zinc-finger domain 64 4e-10
sp|Q9HCE1|MOV10_HUMAN Putative helicase MOV-10 (Moloney leu... 42 0.002
sp|P23249|MOV10_MOUSE Putative helicase MOV-10 (Moloney leu... 42 0.002
sp|Q9BYK8|PR285_HUMAN Peroxisomal proliferator-activated re... 40 0.011
sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 (Silencing ... 39 0.014
sp|P94461|PRIA_BACSU Primosomal protein N' (ATP-dependent h... 39 0.024
sp|Q99MV5|M10L1_MOUSE Putative helicase Mov10l1 (Moloney le... 37 0.069
sp|P27059|RPOB_ASTLO DNA-directed RNA polymerase beta chain... 36 0.12
sp|Q6J5K9|ARMI_DROME Probable RNA helicase armi (Armitage p... 36 0.15
sp|Q9BXT6|M10L1_HUMAN Putative helicase Mov10l1 (Moloney le... 35 0.26
>sp|P42694|HELZ_HUMAN Probable helicase with zinc-finger domain
Length = 1942
Score = 64.3 bits (155), Expect = 4e-10
Identities = 52/168 (30%), Positives = 84/168 (50%), Gaps = 8/168 (4%)
Frame = +1
Query: 139 YRYKYESRSLESVTLCLSKLTVETMNLKNNQSIKIRVNFNFDRLIFDRRHKSLKNIPKYD 318
Y E ++ E + L LS+ E +NL+ + ++ + F +RL H +L D
Sbjct: 555 YEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCEMHYAL------D 608
Query: 319 RLSYNPLVCPSFTRLPYGDDESKVHFTPKKNLNDEQIKLPRLVLRKLE-----TTEIAL- 480
R+ N ++ P + P + ++P + DEQ+ PRL ++ E TT +A+
Sbjct: 609 RIKDNGVLFPDISMTP------TIPWSPNRQW-DEQLD-PRLNAKQKEAVLAITTPLAIQ 660
Query: 481 --PFILNGAFGTGKTQVFAETVMAILKNDRTSSILICTRSYSAGELYL 618
P ++ G +GTGKT A+ V IL+ T ILICT S SA +LY+
Sbjct: 661 LPPVLIIGPYGTGKTFTLAQAVKHILQQQET-RILICTHSNSAADLYI 707
>sp|Q9HCE1|MOV10_HUMAN Putative helicase MOV-10 (Moloney leukemia virus 10 protein)
Length = 1003
Score = 42.4 bits (98), Expect = 0.002
Identities = 37/143 (25%), Positives = 68/143 (47%)
Frame = +1
Query: 235 IKIRVNFNFDRLIFDRRHKSLKNIPKYDRLSYNPLVCPSFTRLPYGDDESKVHFTPKKNL 414
+ +VNF F+R +H++L+ ++ V P L D + K++ ++
Sbjct: 441 LTFKVNFTFNRQPLRVQHRALELTGRWLLWPMLFPVAPRDVPLLPSDVKLKLYDRSLES- 499
Query: 415 NDEQIKLPRLVLRKLETTEIALPFILNGAFGTGKTQVFAETVMAILKNDRTSSILICTRS 594
N EQ++ R ++ TT A P+I+ G GTGKT E + ++K+ + IL C S
Sbjct: 500 NPEQLQAMRHIVTG--TTRPA-PYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPS 556
Query: 595 YSAGELYLNIFNQYIPEFIKQIV 663
S +L ++P I +++
Sbjct: 557 NSGADLLCQRLRVHLPSSIYRLL 579
>sp|P23249|MOV10_MOUSE Putative helicase MOV-10 (Moloney leukemia virus 10 protein)
Length = 1004
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/147 (26%), Positives = 74/147 (50%), Gaps = 4/147 (2%)
Frame = +1
Query: 235 IKIRVNFNFDRLIFDRRHKSLKNIPKYDRLSYNPLVCPSFTR----LPYGDDESKVHFTP 402
+ +VNF F+R +H++L+ ++ P++ P +R LP D + K++
Sbjct: 442 LTFKVNFTFNRQPLRVQHRALELTGRWVLW---PMLFPVASRGVSLLP-SDVKFKLYDRS 497
Query: 403 KKNLNDEQIKLPRLVLRKLETTEIALPFILNGAFGTGKTQVFAETVMAILKNDRTSSILI 582
++ N EQ++ + ++R TT A P+I+ G GTGKT E + ++K+ + IL
Sbjct: 498 LES-NPEQLQAMKHIVRG--TTRPA-PYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILA 553
Query: 583 CTRSYSAGELYLNIFNQYIPEFIKQIV 663
C S S +L ++P I +++
Sbjct: 554 CAPSNSGADLLCQRLRVHLPSSIYRLL 580
>sp|Q9BYK8|PR285_HUMAN Peroxisomal proliferator-activated receptor A interacting complex
285 kDa protein (PPAR-alpha interacting complex protein
285)
Length = 2649
Score = 39.7 bits (91), Expect = 0.011
Identities = 17/46 (36%), Positives = 28/46 (60%)
Frame = +1
Query: 481 PFILNGAFGTGKTQVFAETVMAILKNDRTSSILICTRSYSAGELYL 618
P ++ G FGTGKT A + +++ T +LICT + SA ++Y+
Sbjct: 539 PLLIYGPFGTGKTYTLAMASLEVIRRPET-KVLICTHTNSAADIYI 583
>sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 (Silencing defective protein 3)
Length = 1002
Score = 39.3 bits (90), Expect = 0.014
Identities = 22/66 (33%), Positives = 35/66 (53%)
Frame = +1
Query: 412 LNDEQIKLPRLVLRKLETTEIALPFILNGAFGTGKTQVFAETVMAILKNDRTSSILICTR 591
LN EQI +VL + A P++++G GTGKT E ++ + R + +L+C
Sbjct: 397 LNAEQICSIEMVLG----CKGAPPYVIHGPPGTGKTMTLVEAIVQLYTTQRNARVLVCAP 452
Query: 592 SYSAGE 609
S SA +
Sbjct: 453 SNSAAD 458
>sp|P94461|PRIA_BACSU Primosomal protein N' (ATP-dependent helicase priA) (Replication
factor Y)
Length = 805
Score = 38.5 bits (88), Expect = 0.024
Identities = 32/126 (25%), Positives = 59/126 (46%)
Frame = +1
Query: 358 RLPYGDDESKVHFTPKKNLNDEQIKLPRLVLRKLETTEIALPFILNGAFGTGKTQVFAET 537
R PY D K T L DEQ + L++ E + F+L+G G+GKT+++ ++
Sbjct: 252 RDPYQDKMFKK--TEPLPLTDEQRAAFEPIRETLDSDEHKV-FLLHGVTGSGKTEIYLQS 308
Query: 538 VMAILKNDRTSSILICTRSYSAGELYLNIFNQYIPEFIKQIVFIKSDHKKGEKSEEKTTL 717
+ +L + + +L+ S L + N++ F Q+ + S GEK +E +
Sbjct: 309 IEKVLAKGKEAIVLVPEIS-----LTPQMVNRFKGRFGSQVAVMHSGLSTGEKYDEWRKI 363
Query: 718 FSDQLR 735
++R
Sbjct: 364 HRKEVR 369
>sp|Q99MV5|M10L1_MOUSE Putative helicase Mov10l1 (Moloney leukemia virus 10-like protein
1) (MOV10-like 1) (Cardiac helicase activated by MEF2
protein) (Cardiac-specific RNA helicase)
Length = 1187
Score = 37.0 bits (84), Expect = 0.069
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Frame = +1
Query: 385 KVHFTPKKNLNDEQIKLPRLVLRKLETTEIA-LPFILNGAFGTGKTQVFAETVMAILKND 561
K F P N N +L +R++ + + LP+IL G GTGKT E V+ +
Sbjct: 740 KEFFNPVLNENQ------KLAVRRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHYAL 793
Query: 562 RTSSILICTRSYSAGELY-LNIFNQYIPE 645
S IL+C S SA +L L + +P+
Sbjct: 794 PDSRILVCAPSNSAADLVCLRLHESKVPK 822
>sp|P27059|RPOB_ASTLO DNA-directed RNA polymerase beta chain (PEP) (Plastid-encoded RNA
polymerase beta subunit) (RNA polymerase beta subunit)
Length = 1076
Score = 36.2 bits (82), Expect = 0.12
Identities = 20/81 (24%), Positives = 39/81 (48%)
Frame = +1
Query: 598 SAGELYLNIFNQYIPEFIKQIVFIKSDHKKGEKSEEKTTLFSDQLRNETFNVNRVFVTTI 777
S GEL N FN I + +I+ + ++ +K EEK ++ + + E +N+ +
Sbjct: 299 SVGELMQNKFNNIIKDIYTKIIEKINKFEQKKKQEEK---YNKEKKEEKIKINKTYFINS 355
Query: 778 ENAVDTLTPFISSLQEKSMFN 840
+N D + FI++ + N
Sbjct: 356 KNLTDNIKKFITTNPLSQLLN 376
>sp|Q6J5K9|ARMI_DROME Probable RNA helicase armi (Armitage protein)
Length = 1274
Score = 35.8 bits (81), Expect = 0.15
Identities = 38/166 (22%), Positives = 74/166 (44%), Gaps = 13/166 (7%)
Frame = +1
Query: 154 ESRSLESVTLCLSKLTVETMNLKNNQSIK-------IRVNFNFDRLIFDRRHKSLKNIPK 312
+S++ +S + K+ + + LK + S + R+ F F R F ++H ++ I
Sbjct: 682 DSQTTKSYEGIIHKVLFDRILLKFHSSFQEKYNGEDYRLEFYFSRYSFRKQHHAISKIVG 741
Query: 313 Y---DRLSYNPLVCPSFTRLP-YGDDESKVHFTPKKNLNDEQIKL--PRLVLRKLETTEI 474
D L + + +L Y D+ + K ++ + R V L
Sbjct: 742 VMGEDFLFPSKVTKRENPQLDVYMKDDDMYLYDSKLEWYNQSLNSIQKRAVFNILRGEAE 801
Query: 475 ALPFILNGAFGTGKTQVFAETVMAILKNDRTSSILICTRSYSAGEL 612
+P++L G G+GKT ET++ +++N + IL+ T S S+ +L
Sbjct: 802 NIPYVLFGPPGSGKTMTLIETLLQLVRNLPGARILVGTPSNSSADL 847
>sp|Q9BXT6|M10L1_HUMAN Putative helicase Mov10l1 (Moloney leukemia virus 10-like protein
1) (MOV10-like 1)
Length = 1211
Score = 35.0 bits (79), Expect = 0.26
Identities = 20/45 (44%), Positives = 25/45 (55%)
Frame = +1
Query: 478 LPFILNGAFGTGKTQVFAETVMAILKNDRTSSILICTRSYSAGEL 612
LP+IL G GTGKT E V+ + S IL+C S SA +L
Sbjct: 764 LPYILFGPPGTGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADL 808
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,698,226
Number of Sequences: 369166
Number of extensions: 1642439
Number of successful extensions: 4397
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4271
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4395
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8293644780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)