Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_B03
(844 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9JHS1|EPAS1_RAT Endothelial PAS domain protein 1 (EPAS-... 32 2.9
sp|P18563|ITB6_CAVPO Integrin beta-6 31 3.7
sp|P34545|CBP1_CAEEL Protein cbp-1 31 3.7
sp|P04540|NU5M_TRYBB NADH-ubiquinone oxidoreductase chain 5... 30 6.4
sp|Q9Z0T9|ITB6_MOUSE Integrin beta-6 precursor 30 8.3
sp|Q80X19|COEA1_MOUSE Collagen alpha 1(XIV) chain precursor 30 8.3
sp|P18564|ITB6_HUMAN Integrin beta-6 precursor 30 8.3
>sp|Q9JHS1|EPAS1_RAT Endothelial PAS domain protein 1 (EPAS-1) (Hypoxia-inducible factor
2 alpha) (HIF-2 alpha) (HIF2 alpha)
Length = 874
Score = 31.6 bits (70), Expect = 2.9
Identities = 19/49 (38%), Positives = 22/49 (44%)
Frame = +2
Query: 26 PVCMGQVFSMPLGSSSFRMGPPWPPGSEMGLMDTSASASQSQSGNDISP 172
P C GQ S PL S R PWPP + L T S +QS + P
Sbjct: 617 PPCCGQA-STPLSSMGGRSNTPWPPDPPLHLGPTKWSVG-NQSAEPLGP 663
>sp|P18563|ITB6_CAVPO Integrin beta-6
Length = 577
Score = 31.2 bits (69), Expect = 3.7
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Frame = -2
Query: 282 HYLSGDSGSLMAN-SVTSLASKSRFQLISAVTGS*DPFGLMSLPDCDCDALAEVSINPIS 106
H G++ S S+ + KSR +I V G D ++ P+C CD EV +N
Sbjct: 267 HMKVGETASFNVTVSIPNCERKSRHVIIKPV-GLGDTLEILVSPECSCDCQKEVEVNSSK 325
Query: 105 DPGGQG 88
G G
Sbjct: 326 CHNGNG 331
>sp|P34545|CBP1_CAEEL Protein cbp-1
Length = 2056
Score = 31.2 bits (69), Expect = 3.7
Identities = 14/38 (36%), Positives = 18/38 (47%)
Frame = -2
Query: 129 EVSINPISDPGGQGGPIRKDDDPKGMENT*PIQTGGFS 16
+V NP + GG GGP P+G P GGF+
Sbjct: 39 DVDNNPSTSAGGSGGPSGSTPHPQGTPQPAPSNNGGFN 76
>sp|P04540|NU5M_TRYBB NADH-ubiquinone oxidoreductase chain 5 (NADH dehydrogenase subunit
5)
Length = 590
Score = 30.4 bits (67), Expect = 6.4
Identities = 21/88 (23%), Positives = 40/88 (45%), Gaps = 19/88 (21%)
Frame = +1
Query: 319 NYFMLYAFMYV----CV--CKYHILMYPRVMMSACVRMRVCTMHIYSPIPII-------- 456
NYF+L+ M+V C+ C + + Y ++ + + +C + I+ I +
Sbjct: 426 NYFLLFFLMFVFKCFCLVDCLFLLFDYECCLVYCLISLYMCILSIFFIIDFVCIFVFSSY 485
Query: 457 -----YFLRFYYFSNIDFLYIIIFVILT 525
+FL FY F D ++F+IL+
Sbjct: 486 CVFWSFFLNFYNF--FDIAIFVVFLILS 511
Score = 30.0 bits (66), Expect = 8.3
Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Frame = +1
Query: 334 YAFMYVCVCKYHILMYPRVMMSACVRMRVCTMHIYSPIPIIYFLRFYYFSNIDFLYI-II 510
Y FMY C C L+ ++++C +C + + + L +Y + I+FL+I II
Sbjct: 359 YFFMYFCGCVLARLLLIFAILNSCSIWFLCGFYCKDMLLALLMLLSFY-NIIEFLFISII 417
Query: 511 FVILT 525
F+ T
Sbjct: 418 FIFFT 422
>sp|Q9Z0T9|ITB6_MOUSE Integrin beta-6 precursor
Length = 787
Score = 30.0 bits (66), Expect = 8.3
Identities = 18/65 (27%), Positives = 23/65 (35%)
Frame = -2
Query: 282 HYLSGDSGSLMANSVTSLASKSRFQLISAVTGS*DPFGLMSLPDCDCDALAEVSINPISD 103
H GD+ S S K LI G D ++ +CDCD E+ N
Sbjct: 408 HMKVGDTASFNVTVSVSNCEKRSRNLIIKPVGLGDTLEILVSAECDCDCQREIETNSSKC 467
Query: 102 PGGQG 88
G G
Sbjct: 468 HNGNG 472
>sp|Q80X19|COEA1_MOUSE Collagen alpha 1(XIV) chain precursor
Length = 1797
Score = 30.0 bits (66), Expect = 8.3
Identities = 25/68 (36%), Positives = 30/68 (44%), Gaps = 5/68 (7%)
Frame = -2
Query: 237 TSLASKSRFQLISAVTGS*DPFGLMSLP-DCDCDALAEVSINPISDPGGQG--GP--IRK 73
TS ASK R + G D LP C C EV++ P PGG G GP +
Sbjct: 1425 TSWASKDR---CCELPGLRDEESCPDLPRSCSCSETNEVALGPAGPPGGPGLRGPKGQQG 1481
Query: 72 DDDPKGME 49
+ PKG E
Sbjct: 1482 EQGPKGPE 1489
>sp|P18564|ITB6_HUMAN Integrin beta-6 precursor
Length = 788
Score = 30.0 bits (66), Expect = 8.3
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Frame = -2
Query: 282 HYLSGDSGSLMAN-SVTSLASKSRFQLISAVTGS*DPFGLMSLPDCDCDALAEVSINPIS 106
H GD+ S ++ +SR +I V G D L+ P+C+CD EV +N
Sbjct: 408 HMKVGDTASFSVTVNIPHCERRSRHIIIKPV-GLGDALELLVSPECNCDCQKEVEVNSSK 466
Query: 105 DPGGQG 88
G G
Sbjct: 467 CHHGNG 472
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,299,255
Number of Sequences: 369166
Number of extensions: 1607307
Number of successful extensions: 4259
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3931
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4248
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8245425915
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)