Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_P23
(836 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NRZ5|PLCD_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltra... 119 8e-27
sp|Q8K4X7|PLCD_MOUSE 1-acyl-sn-glycerol-3-phosphate acyltra... 116 9e-26
sp|Q924S1|PLCD_RAT 1-acyl-sn-glycerol-3-phosphate acyltrans... 116 9e-26
sp|Q6IWY1|LPAT2_BRAOL 1-acyl-sn-glycerol-3-phosphate acyltr... 105 2e-22
sp|Q9NRZ7|PLCC_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltra... 100 8e-21
sp|Q5RA57|PLCC_PONPY 1-acyl-sn-glycerol-3-phosphate acyltra... 100 8e-21
sp|Q9D517|PLCC_MOUSE 1-acyl-sn-glycerol-3-phosphate acyltra... 99 1e-20
sp|Q9D1E8|PLCE_MOUSE 1-acyl-sn-glycerol-3-phosphate acyltra... 82 1e-15
sp|Q9NUQ2|PLCE_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltra... 75 3e-13
sp|Q12185|YD18_YEAST Hypothetical 45.9 kDa protein in KCS1-... 64 4e-10
>sp|Q9NRZ5|PLCD_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (1-AGP
acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid
acyltransferase-delta) (LPAAT-delta)
(1-acylglycerol-3-phosphate O-acyltransferase 4)
Length = 378
Score = 119 bits (299), Expect = 8e-27
Identities = 65/161 (40%), Positives = 96/161 (59%)
Frame = +2
Query: 14 WIKDKEIIANSLKNFNKTLPGYINLLLIYPEGTRFTQKKLEASNEVARSKGMPELKHCLL 193
W +D++ +A SL++ Y LI+ EGTRFT+KK E S +VAR+KG+P LKH LL
Sbjct: 148 WEQDRKTVATSLQHLRDYPEKYF--FLIHCEGTRFTEKKHEISMQVARAKGLPRLKHHLL 205
Query: 194 PRTKGFVEVVKNLRSQVDWIYDFTVAFPDSVDSSVKEANTSQPPLTMKNILNAKVKEGNM 373
PRTKGF V++LR+ V +YD T+ F N P T+ +LN K ++
Sbjct: 206 PRTKGFAITVRSLRNVVSAVYDCTLNF----------RNNENP--TLLGVLNGKKYHADL 253
Query: 374 TYERISMKDLPEDDEKLSLWLQERFRKKDTLFDKYVNTGKF 496
RI ++D+PEDD++ S WL + +++KD ++Y TG F
Sbjct: 254 YVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTF 294
>sp|Q8K4X7|PLCD_MOUSE 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (1-AGP
acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid
acyltransferase-delta) (LPAAT-delta)
(1-acylglycerol-3-phosphate O-acyltransferase 4)
Length = 378
Score = 116 bits (290), Expect = 9e-26
Identities = 66/161 (40%), Positives = 93/161 (57%)
Frame = +2
Query: 14 WIKDKEIIANSLKNFNKTLPGYINLLLIYPEGTRFTQKKLEASNEVARSKGMPELKHCLL 193
W +D++ +A SL + Y L LI+ EGTRFT+KK + S +VA++KG+P LKH LL
Sbjct: 148 WEQDRQTVAKSLLHLRDYPEKY--LFLIHCEGTRFTEKKHQISMQVAQAKGLPSLKHHLL 205
Query: 194 PRTKGFVEVVKNLRSQVDWIYDFTVAFPDSVDSSVKEANTSQPPLTMKNILNAKVKEGNM 373
PRTKGF VK LR V +YD T+ F N P T+ +LN K +
Sbjct: 206 PRTKGFAITVKCLRDVVPAVYDCTLNF----------RNNENP--TLLGVLNGKKYHADC 253
Query: 374 TYERISMKDLPEDDEKLSLWLQERFRKKDTLFDKYVNTGKF 496
RI M+D+PED++K S WL + +++KD ++Y TG F
Sbjct: 254 YVRRIPMEDIPEDEDKCSAWLHKLYQEKDAFQEEYYRTGVF 294
>sp|Q924S1|PLCD_RAT 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (1-AGP
acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid
acyltransferase-delta) (LPAAT-delta)
(1-acylglycerol-3-phosphate O-acyltransferase 4)
Length = 378
Score = 116 bits (290), Expect = 9e-26
Identities = 66/161 (40%), Positives = 93/161 (57%)
Frame = +2
Query: 14 WIKDKEIIANSLKNFNKTLPGYINLLLIYPEGTRFTQKKLEASNEVARSKGMPELKHCLL 193
W +D++ +A SL + Y L LI+ EGTRFT+KK + S +VA++KG+P LKH LL
Sbjct: 148 WEQDRQTVAKSLLHLRDYPEKY--LFLIHCEGTRFTEKKHQISMQVAQAKGLPSLKHHLL 205
Query: 194 PRTKGFVEVVKNLRSQVDWIYDFTVAFPDSVDSSVKEANTSQPPLTMKNILNAKVKEGNM 373
PRTKGF VK LR V +YD T+ F N P T+ +LN K +
Sbjct: 206 PRTKGFAITVKCLRDVVPAVYDCTLNF----------RNNENP--TLLGVLNGKKYHADC 253
Query: 374 TYERISMKDLPEDDEKLSLWLQERFRKKDTLFDKYVNTGKF 496
RI M+D+PED++K S WL + +++KD ++Y TG F
Sbjct: 254 YVRRIPMEDIPEDEDKCSAWLHKLYQEKDAFQEEYYRTGVF 294
>sp|Q6IWY1|LPAT2_BRAOL 1-acyl-sn-glycerol-3-phosphate acyltransferase 2 (Lysophosphatidyl
acyltransferase 2)
Length = 391
Score = 105 bits (261), Expect = 2e-22
Identities = 58/164 (35%), Positives = 91/164 (55%)
Frame = +2
Query: 11 DWIKDKEIIANSLKNFNKTLPGYINLLLIYPEGTRFTQKKLEASNEVARSKGMPELKHCL 190
+W KD+ + + L+ N + L ++ EGTRFT+ KL+A+ E A + +P ++ L
Sbjct: 143 NWAKDESTLKSGLQRLNDFPRPF--WLALFVEGTRFTEAKLKAAQEYAATSQLPVPRNVL 200
Query: 191 LPRTKGFVEVVKNLRSQVDWIYDFTVAFPDSVDSSVKEANTSQPPLTMKNILNAKVKEGN 370
+PRTKGFV V N+RS V IYD TVA P + PP TM + + +
Sbjct: 201 IPRTKGFVSAVSNMRSFVPAIYDMTVAIP-----------KTSPPPTMLRLFKGQPSVVH 249
Query: 371 MTYERISMKDLPEDDEKLSLWLQERFRKKDTLFDKYVNTGKFDG 502
+ + SMKDLPE +++++ W +++F KD L DK++ F G
Sbjct: 250 VHIKCHSMKDLPESEDEIAQWCRDQFVAKDALLDKHIAADTFPG 293
>sp|Q9NRZ7|PLCC_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (1-AGP
acyltransferase 3) (1-AGPAT 3) (Lysophosphatidic acid
acyltransferase-gamma) (LPAAT-gamma)
(1-acylglycerol-3-phosphate O-acyltransferase 3)
Length = 376
Score = 99.8 bits (247), Expect = 8e-21
Identities = 60/163 (36%), Positives = 89/163 (54%)
Frame = +2
Query: 14 WIKDKEIIANSLKNFNKTLPGYINLLLIYPEGTRFTQKKLEASNEVARSKGMPELKHCLL 193
W +D++ + L+ + P Y+ LL Y EGTRFT+ K S EVA +KG+P LK+ LL
Sbjct: 148 WEEDRDTVVEGLRRLSD-YPEYMWFLL-YCEGTRFTETKHRVSMEVAAAKGLPVLKYHLL 205
Query: 194 PRTKGFVEVVKNLRSQVDWIYDFTVAFPDSVDSSVKEANTSQPPLTMKNILNAKVKEGNM 373
PRTKGF VK LR V +YD T+ F + + S + IL K E +M
Sbjct: 206 PRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPS------------LLGILYGKKYEADM 253
Query: 374 TYERISMKDLPEDDEKLSLWLQERFRKKDTLFDKYVNTGKFDG 502
R ++D+P D+++ + WL + +++KD L + Y G F G
Sbjct: 254 CVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPG 296
>sp|Q5RA57|PLCC_PONPY 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (1-AGP
acyltransferase 3) (1-AGPAT 3) (Lysophosphatidic acid
acyltransferase-gamma) (LPAAT-gamma)
(1-acylglycerol-3-phosphate O-acyltransferase 3)
Length = 376
Score = 99.8 bits (247), Expect = 8e-21
Identities = 60/163 (36%), Positives = 89/163 (54%)
Frame = +2
Query: 14 WIKDKEIIANSLKNFNKTLPGYINLLLIYPEGTRFTQKKLEASNEVARSKGMPELKHCLL 193
W +D++ + L+ + P Y+ LL Y EGTRFT+ K S EVA +KG+P LK+ LL
Sbjct: 148 WEEDRDTVVEGLRRLSD-YPEYMWFLL-YCEGTRFTETKHRVSMEVAAAKGLPVLKYHLL 205
Query: 194 PRTKGFVEVVKNLRSQVDWIYDFTVAFPDSVDSSVKEANTSQPPLTMKNILNAKVKEGNM 373
PRTKGF VK LR V +YD T+ F + + S + IL K E +M
Sbjct: 206 PRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPS------------LLGILYGKKYEADM 253
Query: 374 TYERISMKDLPEDDEKLSLWLQERFRKKDTLFDKYVNTGKFDG 502
R ++D+P D+++ + WL + +++KD L + Y G F G
Sbjct: 254 CVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPG 296
>sp|Q9D517|PLCC_MOUSE 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (1-AGP
acyltransferase 3) (1-AGPAT 3) (Lysophosphatidic acid
acyltransferase-gamma) (LPAAT-gamma)
(1-acylglycerol-3-phosphate O-acyltransferase 3)
Length = 376
Score = 99.0 bits (245), Expect = 1e-20
Identities = 61/163 (37%), Positives = 86/163 (52%)
Frame = +2
Query: 14 WIKDKEIIANSLKNFNKTLPGYINLLLIYPEGTRFTQKKLEASNEVARSKGMPELKHCLL 193
W +D++ + L+ P Y+ LL Y EGTRFT+ K S EVA SKG+P LK+ LL
Sbjct: 148 WEEDRDTVIEGLRRL-ADYPEYMWFLL-YCEGTRFTETKHRISMEVAASKGLPPLKYHLL 205
Query: 194 PRTKGFVEVVKNLRSQVDWIYDFTVAFPDSVDSSVKEANTSQPPLTMKNILNAKVKEGNM 373
PRTKGF V+ LR V IYD T+ F + + S + IL K E +M
Sbjct: 206 PRTKGFTTAVQCLRGTVAAIYDVTLNFRGNKNPS------------LLGILYGKKYEADM 253
Query: 374 TYERISMKDLPEDDEKLSLWLQERFRKKDTLFDKYVNTGKFDG 502
R ++D+P D+ + WL + +++KD L + Y G F G
Sbjct: 254 CVRRFPLEDIPADETSAAQWLHKLYQEKDALQEMYKQKGVFPG 296
>sp|Q9D1E8|PLCE_MOUSE 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (1-AGP
acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid
acyltransferase-epsilon) (LPAAT-epsilon)
(1-acylglycerol-3-phosphate O-acyltransferase 5)
Length = 365
Score = 82.4 bits (202), Expect = 1e-15
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 9/171 (5%)
Frame = +2
Query: 23 DKEIIANSLKNFNKTLPGYINLLLIYPEGTRFTQ---KKLEASNEVARSKGMPELKHCLL 193
DKE+ + N P Y L+I+PEGTR+ K L AS A +G+ LKH L
Sbjct: 149 DKEMRSKLQSYVNAGTPMY---LVIFPEGTRYNATYTKLLSASQAFAAQRGLAVLKHVLT 205
Query: 194 PRTKGFVEVVKNLRSQVDWIYDFTVAFPDSVDSSVKEANTSQPPLTMKNILNAKVKEGNM 373
PR K +++S +D IYD TV + + S K +N P +M L + + ++
Sbjct: 206 PRIKATHVAFDSMKSHLDAIYDVTVVYEGNEKGSGKYSN----PPSMTEFLCKQCPKLHI 261
Query: 374 TYERISMKDLPEDDEKLSLWLQERFRKKDTLFDKYVNT------GKFDGPS 508
++RI ++PE+ E + WL ERF KD L ++ ++ KF G S
Sbjct: 262 HFDRIDRNEVPEEQEHMKKWLHERFEIKDRLLIEFYDSPDPERRNKFPGKS 312
>sp|Q9NUQ2|PLCE_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (1-AGP
acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid
acyltransferase-epsilon) (LPAAT-epsilon)
(1-acylglycerol-3-phosphate O-acyltransferase 5)
Length = 364
Score = 74.7 bits (182), Expect = 3e-13
Identities = 60/206 (29%), Positives = 91/206 (44%), Gaps = 19/206 (9%)
Frame = +2
Query: 50 KNFNKTLPGYINL-----LLIYPEGTRFTQ---KKLEASNEVARSKGMPELKHCLLPRTK 205
K L Y++ L+I+PEGTR+ K L AS A +G+ LKH L PR K
Sbjct: 150 KEMRNKLQSYVDAGTPMYLVIFPEGTRYNPEQTKVLSASQAFAAQRGLAVLKHVLTPRIK 209
Query: 206 GFVEVVKNLRSQVDWIYDFTVAFPDSVDSSVKEANTSQPPLTMKNILNAKVKEGNMTYER 385
+++ +D IYD TV + D + + TM L + + ++ +R
Sbjct: 210 ATHVAFDCMKNYLDAIYDVTVVYEGKDDGGQRRESP-----TMTEFLCKECPKIHIHIDR 264
Query: 386 ISMKDLPEDDEKLSLWLQERFRKKDTLFDKYVNT----------GKFDGPSRIIEPTI-S 532
I KD+PE+ E + WL ERF KD + ++ + GK I+ T+ S
Sbjct: 265 IDKKDVPEEQEHMRRWLHERFEIKDKMLIEFYESPDPERRKRFPGKSVNSKLSIKKTLPS 324
Query: 533 GLIIYCVTFAVLWFVVGSGLAYILWI 610
LI+ +T +L G L WI
Sbjct: 325 MLILSGLTAGMLMTDAGRKLYVNTWI 350
>sp|Q12185|YD18_YEAST Hypothetical 45.9 kDa protein in KCS1-GCV1 intergenic region
Length = 396
Score = 64.3 bits (155), Expect = 4e-10
Identities = 46/185 (24%), Positives = 84/185 (45%), Gaps = 23/185 (12%)
Frame = +2
Query: 11 DWIKDKEIIANSLKNF--------------------NKTLPGYINLLLIYPEGTRFTQKK 130
+W KD++ + NSL + N+++ Y L+++PEGT + K
Sbjct: 168 NWQKDEKALTNSLVSMDLNARCKGPLTNYKSCYSKTNESIAAYN--LIMFPEGTNLSLKT 225
Query: 131 LEASNEVARSKGMP--ELKHCLLPRTKGFVEVVKNLRSQVDWIYDFTVAFPDSVDSSVKE 304
E S + + +L+H LLP +KG V+ L +D IYD T+ + ++ +
Sbjct: 226 REKSEAFCQRAHLDHVQLRHLLLPHSKGLKFAVEKLAPSLDAIYDVTIGYSPALRTEYVG 285
Query: 305 ANTSQPPLTMKNILNAKVKEGNMTYERISMKDLP-EDDEKLSLWLQERFRKKDTLFDKYV 481
+ + + + KV + + ++P +DDE WL +++KD L + Y
Sbjct: 286 TKFTLKKIFLMGVYPEKV---DFYIREFRVNEIPLQDDEVFFNWLLGVWKEKDQLLEDYY 342
Query: 482 NTGKF 496
NTG+F
Sbjct: 343 NTGQF 347
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,849,635
Number of Sequences: 369166
Number of extensions: 1612428
Number of successful extensions: 4038
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3903
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4022
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8148988185
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)